Abstract:
:This study explores the presence of homogeneous subgroups among 156 normal elderly subjects based on their performance on a battery of neuropsychological tests. Subjects ranged in age between 57 and 85 years and included 62 males and 94 females with a mean age 70.7 years, mean education 14.1 years, and mean Full Scale IQ of 117.2. Six clusters were extracted, three of which are likely to represent preclinical stages of the dementing process with distinct patterns of cognitive deficits. The results are discussed in light of different models of cognitive deterioration in DAT.
journal_name
J Clin Exp Neuropsycholjournal_title
Journal of clinical and experimental neuropsychologyauthors
Mitrushina M,Uchiyama C,Satz Pdoi
10.1080/01688639508405130subject
Has Abstractpub_date
1995-05-01 00:00:00pages
374-82issue
3eissn
1380-3395issn
1744-411Xjournal_volume
17pub_type
杂志文章abstract::A Monozygotic twin pair had febrile seizures, only one was treated with phenobarbital from 17-30 months of age. Standard intellectual and behavioral assessments were conducted during Treatment (30 months of age), and Post-Treatment (32, 41, 48, 66 months of age). Both twins showed normal global intelligence at all ass...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章
doi:10.1080/01688638708405059
更新日期:1987-08-01 00:00:00
abstract:INTRODUCTION:Reactive oxygen species are involved in the functional changes necessary for synaptic plasticity, memory, and cognitive function. It is far from clear whether the increased excitability, and which forms of neuronal excitability, should be considered a part of the learning process or, rather, cellular manif...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章
doi:10.1080/13803395.2015.1007118
更新日期:2015-01-01 00:00:00
abstract::Neuropsychological assessment batteries, which traditionally require lengthy administration times, may be composed of multiple tests which measure essentially the same performance attributes. Test redundancies of this nature compromise the adequacy of a test battery from a cost containment perspective. The present stu...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章
doi:10.1080/01688638508401269
更新日期:1985-08-01 00:00:00
abstract::Ten men (ages 18-39) with clear histories of Infantile autism and approximately average verbal and nonverbal intelligence were studied with a comprehensive battery of neuropsychological tests. Comparisons with 10 matched normal controls showed no significant differences in many visuoperceptual or memory skills or in s...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章
doi:10.1080/01688638808408236
更新日期:1988-03-01 00:00:00
abstract::This article reports on the development and validation of a novel, objective test of judgment for use with older adults. The Test of Practical Judgment (TOP-J) is an open-ended measure that evaluates judgment related to safety, medical, social/ethical, and financial issues. Psychometric features were examined in a sam...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章
doi:10.1080/13825580601025908
更新日期:2007-10-01 00:00:00
abstract::A sample of 278 men and 353 elderly women who resided in the community received the Repeatable Battery for the Assessment of Neuropsychological Status (RBANS) as part of a study of health in mature adult Oklahomans. Females attained significantly higher scores on the Immediate and Delayed Memory and the Language Index...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章
doi:10.1076/jcen.25.8.1065.16732
更新日期:2003-12-01 00:00:00
abstract::Factor structure of the Halstead Category Test was evaluated in patients with schizophrenia, heterogeneous forms of brain damage, and patient controls using confirmatory factor analysis. Analyses were performed including and excluding subtests 1 and 2. In the first analysis, a three-factor model was optimal, with subt...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章
doi:10.1076/jcen.21.2.237.926
更新日期:1999-04-01 00:00:00
abstract:INTRODUCTION:The purpose of this study was to examine the relation between white matter integrity of the brain and postconcussion symptom reporting following mild traumatic brain injury (MTBI). METHOD:Participants were 109 U.S. military service members (91.7% male) who had sustained a MTBI (n = 88) or orthopedic injur...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章
doi:10.1080/13803395.2019.1585518
更新日期:2019-07-01 00:00:00
abstract::Huntington disease (HD) is a neurodegenerative condition with prominent motor (including oculomotor), cognitive, and psychiatric effects. While neuropsychological deficits are present in HD, motor impairments may impact performance on neuropsychological measures, especially those requiring a speeded response, as has b...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章
doi:10.1080/13803395.2015.1101054
更新日期:2016-01-01 00:00:00
abstract::Visuospatial memory was investigated in two groups of patients suffering from senile dementias of the Alzheimer (SDAT) or Lewy body (SDLT) types; a, third, age-matched, healthy control group was also included. The two patient groups were mildly demented and could not be distinguished from each other by traditional tes...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章
doi:10.1080/13803399508406579
更新日期:1995-02-01 00:00:00
abstract:INTRODUCTION:Visuospatial processing and task switching are impaired in individuals with mood disorders. It is unknown whether early deficits are present before mood symptom on set or are related to risk for a specific type of mood disorder. To investigate, we compared visual attention and task switching during sequenc...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章
doi:10.1080/13803395.2017.1401597
更新日期:2018-08-01 00:00:00
abstract::Objective methods for determining clinically relevant neurocognitive change are useful for clinicians and researchers, but the utility of such methods requires validation studies in order to assess their accuracy among target populations. We examined the generalizability of regression equations and reliable change ind...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章
doi:10.1080/13803390600920471
更新日期:2007-08-01 00:00:00
abstract::We examined the Trail Making Test (TMT) in a sample of 767 participants with prodromal Huntington disease (prodromal HD) and 217 healthy comparisons to determine the contributions of motor, psychiatric, and cognitive changes to TMT scores. Eight traditional and derived TMT scores were also evaluated for their ability ...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章
doi:10.1080/13803395.2010.541228
更新日期:2011-06-01 00:00:00
abstract::Previous studies have attributed poor memory for words after left temporal lobectomy (LTL) to a verbal memory deficit and poor memory for abstract designs after right temporal lobectomy (RTL) to a difficulty in remembering nonverbal/visual stimuli. In this investigation, the contribution of stimulus novelty to lateral...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章
doi:10.1076/jcen.25.1.36.13625
更新日期:2003-02-01 00:00:00
abstract:INTRODUCTION:Comparative efficacy and safety are important issues for appropriate drug selection for attention-deficit hyperactivity disorder (ADHD) treatment. Therefore we conducted a meta-analysis, where we compared atomoxetine (ATX) and methylphenidate (MPH) for ADHD treatment in children and adolescents. METHOD:Li...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章,meta分析
doi:10.1080/13803395.2016.1273320
更新日期:2017-11-01 00:00:00
abstract::Introduction: Although there are plenty of studies on affective or cognitive theory of mind (ToM) in Alzheimer's Disease (AD), few have investigated both these dimensions and even fewer have examined the ability to identify an emotion from context in relation to the executive function deficit. Thus, the purpose of thi...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章
doi:10.1080/13803395.2020.1726293
更新日期:2020-05-01 00:00:00
abstract::After a review of Arthur Benton's conceptual and methodological contributions to the understanding of normal and pathological development, we discuss agenesis of the corpus callosum (CC), criteria for potential neuroanatomical compensatory mechanisms in CC agenesis, and the results of an examination of magnetic resona...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章
doi:10.1080/13803390802209954
更新日期:2009-02-01 00:00:00
abstract::The clinical literature in Huntington's disease (HD) suggests that unawareness of deficits is prevalent among HD patients. However, few studies have characterized unawareness of different types of impairment within this neuropsychiatric disorder. The purpose of the current study was to examine self-awareness of functi...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章
doi:10.1080/13803390600718958
更新日期:2007-05-01 00:00:00
abstract::The primary goal of this study was to establish the stability of the Wide Range Achievement Test (WRAT-3) Reading score across two annual assessments of aging individuals. Participants were classified as controls (n = 200), mild cognitive impairment (MCI; n = 137), or possible or probable Alzheimer's disease (AD; n = ...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章
doi:10.1080/13803390802375557
更新日期:2009-07-01 00:00:00
abstract::This pilot study characterizes memory functioning of 11 men with occupational chronic solvent encephalopathy (CSE). Pattern (PRM) and spatial recognition (SRM), spatial span (SSP), spatial working memory (SWM), and paired associate learning (PAL) from Cambridge Neuropsychological Test Automated Battery were performed ...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章
doi:10.1080/13803390500477515
更新日期:2006-11-01 00:00:00
abstract::Fifty-one children who has sustained head injuries were divided into mildly, moderately and severely injured groups according to neurological criteria. The groups were matched for age, sex, and injury-test interval. Approximately 1 year after their injuries, patients were tested on speeded and nonspeeded measures of m...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章
doi:10.1080/01688638508401241
更新日期:1985-02-01 00:00:00
abstract::Visual field deficits in patients have long been considered to be nontreatable, but in previous studies we have found an enlargement of the intact visual field following vision restoration therapy (VRT). In the present pilot study, we wished to determine whether a double-stimulation approach would facilitate visual fi...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 临床试验,杂志文章
doi:10.1080/13803390600878919
更新日期:2007-08-01 00:00:00
abstract::Impulsivity is considered a core feature of problem gambling; however, self-reported impulsivity and inhibitory control may reflect disparate constructs. We examined self-reported impulsivity and inhibitory control in 39 treatment-seeking problem gamblers and 41 matched controls using a range of self-report questionna...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章
doi:10.1080/13803395.2013.873773
更新日期:2014-01-01 00:00:00
abstract::To examine the progression of neuropsychologic and metabolic changes in the early stages of dementia of the Alzheimer type (DAT), we studied 11 midly demented patients longitudinally. Three aspects of neuropsychological function were measured: memory, attention to complex sets and abstract reasoning, and lateralized f...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章
doi:10.1080/01688638808402796
更新日期:1988-10-01 00:00:00
abstract::A battery of psychoeducational tests was administered to samples of high-functioning (IQ > 70) autistic subjects and normal controls. A previous psychoeducational study indicated the presence of preserved procedural and mechanical academic skills accompanied by impaired comprehension and interpretive skills in high-fu...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章
doi:10.1080/01688639408402680
更新日期:1994-10-01 00:00:00
abstract::Attentional lapses are usually defined as temporary and often brief shifts of attention away from some primary task to unrelated internal information processing. This study addressed the incidence of attention lapses and differences in attentional functioning in 30 children with attention-deficit/hyperactivity disorde...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章
doi:10.1080/13803395.2016.1249828
更新日期:2017-08-01 00:00:00
abstract::Declarative and procedural learning were assessed in patients with probable Alzheimer's Disease (AD) and major depression, patients with AD and no depression, patients with major depression but no dementia, and a group of age-comparable nondemented and nondepressed normal controls. AD patients showed significant defic...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章
doi:10.1080/01688639508402433
更新日期:1995-12-01 00:00:00
abstract::The Modified Mini-Mental State Examination (3MS) is an expanded and modified version of the Mini-Mental Status Exam (MMSE). Although the MMSE has achieved widespread clinical use as a brief cognitive screen, the utility of the measure to ascertain cognitive impairment is constrained by a limited set of abilities sampl...
journal_title:Journal of clinical and experimental neuropsychology
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更新日期:2003-04-01 00:00:00
abstract::Indices from the Minnesota Multiphasic Personality Inventory-2 (MMPI-2; Butcher, Dahlstrom, Graham, Tellegen, & Kaemmer, 1989) representing cognitive and emotional disturbance as well as incomplete effort on the Recognition Memory Test (RMT; Warrington, 1984) were examined as predictors of performance on the Halstead-...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章
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更新日期:2006-01-01 00:00:00
abstract:INTRODUCTION:Emotion dysregulation (ED) has long been recognized in clinical descriptions of attention-deficit hyperactivity disorder (ADHD), but a renewed interest in ED has advanced research on the overlap between the two entities. Autonomic reactivity (AR) is a neurobiological correlate of emotion regulation; howeve...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章
doi:10.1080/13803395.2017.1353952
更新日期:2018-05-01 00:00:00