The impact of oculomotor functioning on neuropsychological performance in Huntington disease.

Abstract:

:Huntington disease (HD) is a neurodegenerative condition with prominent motor (including oculomotor), cognitive, and psychiatric effects. While neuropsychological deficits are present in HD, motor impairments may impact performance on neuropsychological measures, especially those requiring a speeded response, as has been demonstrated in multiple sclerosis and schizophrenia. The current study is the first to explore associations between oculomotor functions and neuropsychological performance in HD. Participants with impaired oculomotor functioning performed worse than those with normal oculomotor functioning on cognitive tasks requiring oculomotor involvement, particularly on psychomotor speed tasks, controlling for covariates. Consideration of oculomotor dysfunction on neuropsychological performance is critical, particularly for populations with motor deficits.

authors

Carvalho JO,Long JD,Westervelt HJ,Smith MM,Bruce JM,Kim JI,Mills JA,Paulsen JS,PREDICT-HD Investigators And Coordinators Of The Huntington Study Group.

doi

10.1080/13803395.2015.1101054

subject

Has Abstract

pub_date

2016-01-01 00:00:00

pages

217-26

issue

2

eissn

1380-3395

issn

1744-411X

journal_volume

38

pub_type

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