Abstract:
:Huntington disease (HD) is a neurodegenerative condition with prominent motor (including oculomotor), cognitive, and psychiatric effects. While neuropsychological deficits are present in HD, motor impairments may impact performance on neuropsychological measures, especially those requiring a speeded response, as has been demonstrated in multiple sclerosis and schizophrenia. The current study is the first to explore associations between oculomotor functions and neuropsychological performance in HD. Participants with impaired oculomotor functioning performed worse than those with normal oculomotor functioning on cognitive tasks requiring oculomotor involvement, particularly on psychomotor speed tasks, controlling for covariates. Consideration of oculomotor dysfunction on neuropsychological performance is critical, particularly for populations with motor deficits.
journal_name
J Clin Exp Neuropsycholjournal_title
Journal of clinical and experimental neuropsychologyauthors
Carvalho JO,Long JD,Westervelt HJ,Smith MM,Bruce JM,Kim JI,Mills JA,Paulsen JS,PREDICT-HD Investigators And Coordinators Of The Huntington Study Group.doi
10.1080/13803395.2015.1101054subject
Has Abstractpub_date
2016-01-01 00:00:00pages
217-26issue
2eissn
1380-3395issn
1744-411Xjournal_volume
38pub_type
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