"Vascular depression" predicts verbal fluency in older adults.

Abstract:

:Past research has found links among cerebrovascular risk factors (CVRFs), depression, and cognition in older adults. This study investigated how well baseline cerebrovascular burden and depression predicted verbal fluency three and six months later. Participants were 139 medical rehabilitation patients, age 60 and above. The Geriatric Depression Scale, Charlson Co-Morbidity Index, and Dementia Rating Scale were administered at baseline, and verbal fluency was measured three and six months later. Structural equation modeling found that depression significantly predicted verbal fluency at both time points, independently of demographic variables, baseline cognition, or medical burden. CVRFs correlated with depressive symptoms but did not independently predict verbal fluency. Findings suggest that vascular depression may be a possible signal of impaired brain integrity, consistent with Alexopoulos and colleague's (2000) conceptual framework.

authors

Yochim BP,MacNeill SE,Lichtenberg PA

doi

10.1080/13803390590949322

subject

Has Abstract

pub_date

2006-05-01 00:00:00

pages

495-508

issue

4

eissn

1380-3395

issn

1744-411X

pii

K3478W5KV2X12342

journal_volume

28

pub_type

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