Do subgroups of patients with Alzheimer's disease exhibit asymmetric deficits on memory tests?

Abstract:

:Several studies have reported asymmetric cognitive profiles in patients with Alzheimer's disease (AD), but these results have almost exclusively been found using non-memory cognitive instruments. The present study investigated whether AD patients who display lateralized profiles on non-memory cognitive instruments also exhibit asymmetric deficits on verbal versus spatial memory tests. Sixty-eight AD patients participated in the study: 36 with a "High Verbal" cognitive profile, and 32 with a "High Spatial" profile. The results indicated that the High Verbal AD patients performed significantly better than the High Spatial AD patients on verbal memory tests, but the two subgroups failed to differ on spatial memory tests. Implications of these findings for understanding the heterogeneous nature of cognitive profiles in AD patients are discussed.

authors

Demadura T,Delis DC,Jacobson M,Salmon D

doi

10.1076/jcen.23.2.164.1207

subject

Has Abstract

pub_date

2001-04-01 00:00:00

pages

164-71

issue

2

eissn

1380-3395

issn

1744-411X

journal_volume

23

pub_type

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