Abstract:
:Several studies have reported asymmetric cognitive profiles in patients with Alzheimer's disease (AD), but these results have almost exclusively been found using non-memory cognitive instruments. The present study investigated whether AD patients who display lateralized profiles on non-memory cognitive instruments also exhibit asymmetric deficits on verbal versus spatial memory tests. Sixty-eight AD patients participated in the study: 36 with a "High Verbal" cognitive profile, and 32 with a "High Spatial" profile. The results indicated that the High Verbal AD patients performed significantly better than the High Spatial AD patients on verbal memory tests, but the two subgroups failed to differ on spatial memory tests. Implications of these findings for understanding the heterogeneous nature of cognitive profiles in AD patients are discussed.
journal_name
J Clin Exp Neuropsycholjournal_title
Journal of clinical and experimental neuropsychologyauthors
Demadura T,Delis DC,Jacobson M,Salmon Ddoi
10.1076/jcen.23.2.164.1207subject
Has Abstractpub_date
2001-04-01 00:00:00pages
164-71issue
2eissn
1380-3395issn
1744-411Xjournal_volume
23pub_type
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