Abstract:
:The relationships between intermediate visual processes, involving object and space perception, and regional brain activity using positron emission tomography and single photon emission tomography were investigated in 16 patients with Alzheimer's disease. Significant region specific correlations were found between unfamiliar face matching and cerebral activity in the left occipito-temporal region and middle/inferior temporal regions bilaterally. Letter-word identification correlated significantly with brain activity in the angular gyri and occipital association cortices bilaterally, as well as a broad region of activation in the left hemisphere temporal, parietal and occipital lobes. Additionally, a significant correlation was found between ratings of performance of instrumental activities of daily living and brain activity in occipito-temporal and middle/inferior temporal regions. The present study demonstrates that the neuropathological distribution typically seen in Alzheimer's disease corresponds to impairments in specific aspects of intermediate visual perceptual processing, and it is related to the daily living skills of patients with Alzheimer's disease.
journal_name
J Clin Exp Neuropsycholjournal_title
Journal of clinical and experimental neuropsychologyauthors
van Rhijn SJ,Glosser G,de Vries JJ,Clark CM,Newberg AB,Alavi Adoi
10.1076/jcen.26.1.11.23931subject
Has Abstractpub_date
2004-02-01 00:00:00pages
11-23issue
1eissn
1380-3395issn
1744-411Xjournal_volume
26pub_type
杂志文章abstract:INTRODUCTION:Drowning is a serious and frequently neglected public health threat. Primary respiratory impairment after submersion often leads to brain dysfunction. Depending on the period of global hypoxia (respiratory failure), clinical aspects of neurological dysfunction are evident on the first evaluation after the ...
journal_title:Journal of clinical and experimental neuropsychology
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abstract:INTRODUCTION:Attention-deficit/hyperactivity disorder (ADHD) and anxiety are frequently comorbid disorders associated with different types of abnormal performance on neuropsychological tests. Although some studies have shown that comorbid anxiety alters ADHD test performance, results inconsistently show both improvemen...
journal_title:Journal of clinical and experimental neuropsychology
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abstract::The relationships between hemispheric function and components of the imagery process were examined in patients with unilateral right and left brain damage and in intact adult subjects. In the image generation condition, subjects were required to mentally generate Katakana letters corresponding to Hiragana letters disp...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章
doi:10.1080/01688639408402669
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abstract::The aim of this study was to validate the CogState Brief Battery, which assesses psychomotor, attentional, working memory, and visual learning functions, in healthy older people and in patients with mild cognitive impairment (MCI) and Alzheimer's disease (AD), enrolled in the Australian Imaging, Biomarkers and Lifesty...
journal_title:Journal of clinical and experimental neuropsychology
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journal_title:Journal of clinical and experimental neuropsychology
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doi:10.1076/jcen.25.1.36.13625
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abstract::The clinical literature in Huntington's disease (HD) suggests that unawareness of deficits is prevalent among HD patients. However, few studies have characterized unawareness of different types of impairment within this neuropsychiatric disorder. The purpose of the current study was to examine self-awareness of functi...
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journal_title:Journal of clinical and experimental neuropsychology
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journal_title:Journal of clinical and experimental neuropsychology
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journal_title:Journal of clinical and experimental neuropsychology
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journal_title:Journal of clinical and experimental neuropsychology
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journal_title:Journal of clinical and experimental neuropsychology
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