Relationship between the apolipoprotein E gene and headache following sports-related concussion.

Abstract:

INTRODUCTION:Headache is one of the most commonly reported and longest lasting symptoms that concussed athletes report, yet the etiology of headache symptoms following concussion is not entirely clear. The purpose of this study was to determine whether the e4 allele of the apolipoprotein E (APOE) gene influences the presence and severity of postconcussion headache. METHOD:Participants were composed of 45 concussed athletes and 43 healthy/nonconcussed athletes who were involved in a clinically based sports concussion management program. All athletes completed the Post-Concussion Symptom Scale (PCSS). The "headache" symptom from the PCSS was the primary outcome variable. Buccal samples were collected and analyzed to determine APOE genotype. RESULTS:A significantly greater proportion of concussed e4+ athletes than e4- athletes endorsed headache. Furthermore, concussed e4+ athletes endorsed more severe headaches than e4- athletes. When examining the healthy/nonconcussed sample (i.e., athletes at baseline), results showed no differences between e4 allele groups with respect to the presence and severity of headache. CONCLUSIONS:These findings show that when compared to concussed e4- athletes, e4+ athletes are more likely to (a) endorse postconcussion headache and (b) report more severe headache symptoms following concussion. Conversely, it appears that the e4 allele does not influence baseline reports of headache. Thus, results suggest that those with the e4 genotype may be at a higher risk for experiencing headache-related difficulties only after a concussion is sustained.

authors

Merritt VC,Ukueberuwa DM,Arnett PA

doi

10.1080/13803395.2016.1177491

subject

Has Abstract

pub_date

2016-11-01 00:00:00

pages

941-9

issue

9

eissn

1380-3395

issn

1744-411X

journal_volume

38

pub_type

杂志文章
  • Prediction of psychosocial recovery after head injury with cognitive tests and neurobehavioral ratings.

    abstract::A series of 53 patients was studied using a battery of tests and a neurobehavioral rating scale on average 4 months after closed-head injury (CHI). Social outcome was assessed 1 year after injury by interviewing a family member. The results supported the hypothesis that tests of flexibility and programming rather than...

    journal_title:Journal of clinical and experimental neuropsychology

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1080/01688639408402643

    authors: Vilkki J,Ahola K,Holst P,Ohman J,Servo A,Heiskanen O

    更新日期:1994-06-01 00:00:00

  • Deterioration of generic knowledge in patients with Alzheimer's disease: evidence from the Number Information Test.

    abstract::Semantic memory for generic knowledge was assessed in patients with probable Alzheimer's disease (AD; n = 142) and elderly normal control (NC; n = 78) subjects using the Number Information Test (NIT), a test that consists of 24 general knowledge questions that require a single number for an answer (e.g., "How many day...

    journal_title:Journal of clinical and experimental neuropsychology

    pub_type: 临床试验,杂志文章

    doi:10.1080/01688639708403766

    authors: Norton LE,Bondi MW,Salmon DP,Goodglass H

    更新日期:1997-12-01 00:00:00

  • Exploring cognitive reserve in multiple sclerosis: New findings from a cross-sectional study.

    abstract:INTRODUCTION:The cognitive reserve (CR) hypothesis attempts to explain the discrepancy between brain damage and clinical manifestations in neurodegenerative diseases. Recently the concept of CR was applied to the multiple sclerosis (MS) model. Our aim is to investigate the impact of demographic and clinical variables o...

    journal_title:Journal of clinical and experimental neuropsychology

    pub_type: 杂志文章

    doi:10.1080/13803395.2016.1200538

    authors: Nunnari D,De Cola MC,Costa A,Rifici C,Bramanti P,Marino S

    更新日期:2016-12-01 00:00:00

  • Examining Rey Complex Figure Test organization in healthy adults.

    abstract:INTRODUCTION:The Rey Complex Figure Test (RCFT) is a popular measure of visuospatial and executive functioning. Clinical interpretations of RCFT performance are partly based on how an individual approaches the task with piecemeal organization often considered indicative of impairment. This is despite little previous re...

    journal_title:Journal of clinical and experimental neuropsychology

    pub_type: 杂志文章

    doi:10.1080/13803395.2015.1075473

    authors: Wilson NA,Batchelor J

    更新日期:2015-01-01 00:00:00

  • Different cortical source activation patterns in children with attention deficit hyperactivity disorder during a time reproduction task.

    abstract::Several neurocognitive studies have indicated that children with attention-deficit/hyperactivity disorder (ADHD) exhibit cognitive deficits in perceptual timing functions; however, only a few electroencephalographic studies have investigated their time reproduction abilities. In the present research, 15 children with ...

    journal_title:Journal of clinical and experimental neuropsychology

    pub_type: 杂志文章

    doi:10.1080/13803395.2017.1406897

    authors: Khoshnoud S,Shamsi M,Nazari MA,Makeig S

    更新日期:2018-09-01 00:00:00

  • Use of the CogState Brief Battery in the assessment of Alzheimer's disease related cognitive impairment in the Australian Imaging, Biomarkers and Lifestyle (AIBL) study.

    abstract::The aim of this study was to validate the CogState Brief Battery, which assesses psychomotor, attentional, working memory, and visual learning functions, in healthy older people and in patients with mild cognitive impairment (MCI) and Alzheimer's disease (AD), enrolled in the Australian Imaging, Biomarkers and Lifesty...

    journal_title:Journal of clinical and experimental neuropsychology

    pub_type: 杂志文章

    doi:10.1080/13803395.2011.643227

    authors: Lim YY,Ellis KA,Harrington K,Ames D,Martins RN,Masters CL,Rowe C,Savage G,Szoeke C,Darby D,Maruff P,The Aibl Research Group

    更新日期:2012-01-01 00:00:00

  • Cognitive impairment following chemotherapy for breast cancer: The impact of practice effect on results.

    abstract::Chemotherapy-Related Cognitive Impairment (CRCI) can be an adverse effect in women treated for breast cancer. Some longitudinal studies reported deficits in attention, memory, and executive function following treatment, but other studies did not find cognitive changes. It is known that practice effects (PE) on repeate...

    journal_title:Journal of clinical and experimental neuropsychology

    pub_type: 杂志文章

    doi:10.1080/13803395.2018.1546381

    authors: Cerulla N,Arcusa À,Navarro JB,de la Osa N,Garolera M,Enero C,Chico G,Fernández-Morales L

    更新日期:2019-04-01 00:00:00

  • Wisconsin Card Sorting Test performance as a measure of frontal lobe damage.

    abstract::We examined the sensitivity and specificity of the Wisconsin Card Sorting Test (WCST) as a measure of frontal lobe damage in 91 subjects with stable focal brain lesions. Anatomical information about the location and extent of brain damage was obtained from MR and CT transparencies. No significant differences in WCST p...

    journal_title:Journal of clinical and experimental neuropsychology

    pub_type: 杂志文章

    doi:10.1080/01688639108405107

    authors: Anderson SW,Damasio H,Jones RD,Tranel D

    更新日期:1991-11-01 00:00:00

  • About the power for detecting severe impairment in older adults with the Faces test from Wechsler Memory Scale-III: simply guess and save face.

    abstract::The Faces test from Wechsler Memory Scale-III is a widely used instrument for detecting impairment in visual memory. However, the degree to which this test actually achieves its purpose may be seriously hampered by error due to guessing. This problem becomes all the more pronounced among elderly clients, where impairm...

    journal_title:Journal of clinical and experimental neuropsychology

    pub_type: 杂志文章

    doi:10.1076/jcen.25.3.376.13804

    authors: Boaz L

    更新日期:2003-05-01 00:00:00

  • Patients with Huntington's disease have impaired awareness of cognitive, emotional, and functional abilities.

    abstract::The clinical literature in Huntington's disease (HD) suggests that unawareness of deficits is prevalent among HD patients. However, few studies have characterized unawareness of different types of impairment within this neuropsychiatric disorder. The purpose of the current study was to examine self-awareness of functi...

    journal_title:Journal of clinical and experimental neuropsychology

    pub_type: 杂志文章

    doi:10.1080/13803390600718958

    authors: Hoth KF,Paulsen JS,Moser DJ,Tranel D,Clark LA,Bechara A

    更新日期:2007-05-01 00:00:00

  • Neuropsychology of chronic fatigue syndrome: a critical review.

    abstract::This article provides a comprehensive and critical review of the neuropsychological and related literature on chronic fatigue syndrome (CFS). Despite the methodological limitations observed in several studies, some consistent findings are noted. The most consistently documented neuropsychological impairments are in th...

    journal_title:Journal of clinical and experimental neuropsychology

    pub_type: 杂志文章,评审

    doi:10.1080/01688639708403744

    authors: Tiersky LA,Johnson SK,Lange G,Natelson BH,DeLuca J

    更新日期:1997-08-01 00:00:00

  • Some analyses of forgetting of pictorial material in amnesic and demented patients.

    abstract::Three experiments evaluating the rate of forgetting of pictorial stimuli in amnesic, demented, and normal control subjects are reported. When prolonged exposures of pictorial material were used to equate recognition performance after a 10-min delay, alcoholic Korsakoff (AK) patients and patients with Huntington's Dise...

    journal_title:Journal of clinical and experimental neuropsychology

    pub_type: 杂志文章

    doi:10.1080/01688638608401309

    authors: Martone M,Butters N,Trauner D

    更新日期:1986-06-01 00:00:00

  • Selective reminding test: an examination of the equivalence of four forms.

    abstract::Four forms of a selective reminding test were administered to 20 male and 20 female subjects 1 week apart in one of four orders determined by a Latin square. On many of the dependent measures, Form 1 was significantly more difficult than the other three forms, which were equivalent in difficulty. For many of the measu...

    journal_title:Journal of clinical and experimental neuropsychology

    pub_type: 杂志文章

    doi:10.1080/01688638508401258

    authors: Hannay HJ,Levin HS

    更新日期:1985-06-01 00:00:00

  • Prechemotherapy differences in response inhibition in breast cancer patients compared to controls: a functional magnetic resonance imaging study.

    abstract::Prechemotherapy neuroimaging data are lacking in posttreatment cognitive impairment studies. Breast cancer patients and noncancer controls were scanned prior to chemotherapy during a response inhibition task. Task reaction times and error rates, as well as neuropsychological tests, hospital records, and salivary bioma...

    journal_title:Journal of clinical and experimental neuropsychology

    pub_type: 杂志文章

    doi:10.1080/13803395.2012.666227

    authors: Scherling C,Collins B,Mackenzie J,Bielajew C,Smith A

    更新日期:2012-01-01 00:00:00

  • Working memory, response inhibition, and within-subject variability in children with attention-deficit/hyperactivity disorder or reading disorder.

    abstract::This study compared children with ADHD (n = 19), reading disorder (RD; n = 17), ADHD+RD (n = 21), and control children (n = 19) on linguistic and executive function measures. We found no evidence of response inhibition problems in ADHD or RD when a baseline measure of functioning was taken into account. General workin...

    journal_title:Journal of clinical and experimental neuropsychology

    pub_type: 杂志文章

    doi:10.1080/13803390903066865

    authors: Van De Voorde S,Roeyers H,Verté S,Wiersema JR

    更新日期:2010-04-01 00:00:00

  • Test-retest stability on the WRAT-3 reading subtest in geriatric cognitive evaluations.

    abstract::The primary goal of this study was to establish the stability of the Wide Range Achievement Test (WRAT-3) Reading score across two annual assessments of aging individuals. Participants were classified as controls (n = 200), mild cognitive impairment (MCI; n = 137), or possible or probable Alzheimer's disease (AD; n = ...

    journal_title:Journal of clinical and experimental neuropsychology

    pub_type: 杂志文章

    doi:10.1080/13803390802375557

    authors: Ashendorf L,Jefferson AL,Green RC,Stern RA

    更新日期:2009-07-01 00:00:00

  • Reliability and validity of useful field of view test scores as administered by personal computer.

    abstract::The Useful Field of View test (UFOV(1)) is a measure of processing speed that predicts driving performance and other functional abilities in older adults. In comparison to a number of other visual and cognitive measures, the UFOV measure has consistently been found to be the strongest predictor of motor vehicle crashe...

    journal_title:Journal of clinical and experimental neuropsychology

    pub_type: 杂志文章

    doi:10.1080/13803390490515432

    authors: Edwards JD,Vance DE,Wadley VG,Cissell GM,Roenker DL,Ball KK

    更新日期:2005-07-01 00:00:00

  • Prospective evaluation of first and last memory reports following moderate to severe traumatic brain injury.

    abstract::Prospective monitoring of posttraumatic amnesia (PTA) status is recommended following traumatic brain injury (TBI). Use of patients' subjective reports is, however, still common and necessary in some circumstances. It is therefore important to understand how patients' self-reported first memories relate to prospective...

    journal_title:Journal of clinical and experimental neuropsychology

    pub_type: 杂志文章

    doi:10.1080/13803395.2018.1490392

    authors: Roberts CM,Spitz G,Mundy M,Ponsford JL

    更新日期:2019-03-01 00:00:00

  • Visual processing impairments and decrements in regional brain activity in Alzheimer's disease.

    abstract::The relationships between intermediate visual processes, involving object and space perception, and regional brain activity using positron emission tomography and single photon emission tomography were investigated in 16 patients with Alzheimer's disease. Significant region specific correlations were found between unf...

    journal_title:Journal of clinical and experimental neuropsychology

    pub_type: 杂志文章

    doi:10.1076/jcen.26.1.11.23931

    authors: van Rhijn SJ,Glosser G,de Vries JJ,Clark CM,Newberg AB,Alavi A

    更新日期:2004-02-01 00:00:00

  • Normative data of a brief neuropsychological battery for Spanish individuals older than 49.

    abstract::There is an increasing need for standardized assessment of cognition in older patients that is relatively brief, easy to administer, and has normative data adjusted for age and educational attainment. We tested 332 literate, cognitively normal, Spanish persons older than 49 years from the Memory Clinic of Fundació ACE...

    journal_title:Journal of clinical and experimental neuropsychology

    pub_type: 杂志文章

    doi:10.1080/13803395.2011.630652

    authors: Alegret M,Espinosa A,Vinyes-Junqué G,Valero S,Hernández I,Tárraga L,Becker JT,Boada M

    更新日期:2012-01-01 00:00:00

  • Cognitive reserve and lifestyle.

    abstract::The concept of cognitive reserve (CR) suggests that innate intelligence or aspects of life experience like educational or occupational attainments may supply reserve, in the form of a set of skills or repertoires that allows some people to cope with progressing Alzheimer's disease (AD) pathology better than others. Th...

    journal_title:Journal of clinical and experimental neuropsychology

    pub_type: 杂志文章,评审

    doi:10.1076/jcen.25.5.625.14576

    authors: Scarmeas N,Stern Y

    更新日期:2003-08-01 00:00:00

  • Vulnerabilities in sequencing and task switching in healthy youth offspring of parents with mood disorders.

    abstract:INTRODUCTION:Visuospatial processing and task switching are impaired in individuals with mood disorders. It is unknown whether early deficits are present before mood symptom on set or are related to risk for a specific type of mood disorder. To investigate, we compared visual attention and task switching during sequenc...

    journal_title:Journal of clinical and experimental neuropsychology

    pub_type: 杂志文章

    doi:10.1080/13803395.2017.1401597

    authors: Singh MK,Leslie SM,Bhattacharjee K,Gross M,Weisman EF,Soudi LM,Phillips OR,Onopa A

    更新日期:2018-08-01 00:00:00

  • Presidents Test performance in varieties of diffuse and unilateral cerebral disease.

    abstract::Two studies addressed issues concerning the validity of the Presidents Test. The results of Study 1 substantiated that generalized impairment for recent presidents occurs frequently in the context of multifocal and diffuse cerebral disease. Performances of normal elderly (n = 31) on all four Presidents subtests were s...

    journal_title:Journal of clinical and experimental neuropsychology

    pub_type: 杂志文章

    doi:10.1080/01688639008400967

    authors: Roberts RJ,Hamsher KD,Bayless JD,Lee GP

    更新日期:1990-03-01 00:00:00

  • Neuropsychological test performance of patients with Friedreich's ataxia.

    abstract::Although recognized as one of the most common hereditary diseases of the nervous system, the neuropsychological deficits in Friedreich's ataxia (FA) have rarely been studied. A protocol was constructed to assess the major cognitive areas in patients with FA and pair-matched normal controls. Motor difficulties, dysarth...

    journal_title:Journal of clinical and experimental neuropsychology

    pub_type: 杂志文章

    doi:10.1076/jcen.24.5.677.1014

    authors: Wollmann T,Barroso J,Monton F,Nieto A

    更新日期:2002-08-01 00:00:00

  • Wechsler Intelligence Scale profiles, the cholinergic system, and Alzheimer's disease.

    abstract::Forty-one patients with putative Alzheimer's Disease (AD) were evaluated to determine the diagnostic utility of a profile of Wechsler Adult Intelligence Scale (WAIS) subtests which has been proposed by Fuld (1984) to identify cholinergic dysfunction. Only nine (21.9%) of these patients had positive Wechsler profiles. ...

    journal_title:Journal of clinical and experimental neuropsychology

    pub_type: 杂志文章

    doi:10.1080/01688638708405359

    authors: Filley CM,Kobayashi J,Heaton RK

    更新日期:1987-04-01 00:00:00

  • Computerized assessment of sustained attention: interactive effects of task demand, noise, and anxiety.

    abstract::In a sample of 163 college undergraduates, the effects of task demand, noise, and anxiety on Continuous Performance Test (CPT) errors were evaluated with multiple regression and multivariate analysis of variance. Results indicated significantly more omission errors on the difficult task. Complex interaction effects of...

    journal_title:Journal of clinical and experimental neuropsychology

    pub_type: 杂志文章

    doi:10.1080/01688639608408308

    authors: Ballard JC

    更新日期:1996-12-01 00:00:00

  • The blindside: impact of monocular occlusion on spatial attention.

    abstract::Monocular occlusion has been posited to reduce activation of the contralateral hemisphere ("Sprague effect"), thus inducing a contralateral spatial bias (toward the viewing eye). Healthy right-handed participants bisected horizontal lines during monocular eye viewing. Although subjects tended to deviate away from the ...

    journal_title:Journal of clinical and experimental neuropsychology

    pub_type: 杂志文章

    doi:10.1080/13803395.2013.770824

    authors: Burtis DB,Williamson JB,Mishra M,Heilman KM

    更新日期:2013-01-01 00:00:00

  • Boston naming test short forms: a comparison of previous forms with new item response theory based forms.

    abstract::Two new short forms of the Boston Naming Test (BNT) were developed using item response theory (IRT) with data from 206 elderly outpatients. We evaluated the diagnostic ability of 12 short forms among the full sample and in a sub-sample of 69 patients diagnosed with mild Alzheimer's disease (AD) either alone or in comb...

    journal_title:Journal of clinical and experimental neuropsychology

    pub_type: 杂志文章

    doi:10.1080/13803390490510716

    authors: Graves RE,Bezeau SC,Fogarty J,Blair R

    更新日期:2004-10-01 00:00:00

  • Effects of information processing speed on learning, memory, and executive functioning in people living with HIV/AIDS.

    abstract:INTRODUCTION:It is unclear whether or to what degree literacy, aging, and other neurologic abnormalities relate to cognitive deficits among people living with HIV/AIDS in the combined antiretroviral therapy (CART) era. The primary aim of this study was to simultaneously examine the association of age, HIV-associated mo...

    journal_title:Journal of clinical and experimental neuropsychology

    pub_type: 杂志文章

    doi:10.1080/13803395.2014.943696

    authors: Fellows RP,Byrd DA,Morgello S

    更新日期:2014-01-01 00:00:00

  • Object perception impairments predict instrumental activities of daily living dependence in Alzheimer's disease.

    abstract::This study examined the contribution of object perception and spatial localization to functional dependence among Alzheimer's disease (AD) patients. Forty patients with probable AD completed measures assessing verbal recognition memory, working memory, object perception, spatial localization, semantic knowledge, and g...

    journal_title:Journal of clinical and experimental neuropsychology

    pub_type: 杂志文章

    doi:10.1080/13803390591001034

    authors: Jefferson AL,Barakat LP,Giovannetti T,Paul RH,Glosser G

    更新日期:2006-08-01 00:00:00