Effects of anti-CD70 mAb on Theiler's murine encephalomyelitis virus-induced demyelinating disease.

abstract：:Microinfusion of the metabolically stable substance P (SP) agonist, [pGlu5,MePhe8,Sar9]-SP5-11 (DiMe-C7), into the ventral tegmental area (VTA) of rat brain increased levels of the dopamine (DA) metabolite dihydroxyphenylacetic acid in the prefrontal cortex (+ 120%) and nucleus accumbens (+30%) but not in other region...

journal_title：Brain research

authors： Elliott PJ,Alpert JE,Bannon MJ,Iversen SD

更新日期：1986-01-15 00:00:00

abstract：:Responses to rotation in many vertical and horizontal planes were studied in electrically identified secondary vestibular neurons of alert cats. This report concerns secondary neurons that gave responses which could not be explained as due to a summation of semicircular canal inputs. These cells responded to sinusoida...

journal_title：Brain research

authors： Baker J,Goldberg J,Hermann G,Peterson B

更新日期：1984-02-27 00:00:00

abstract：:The interposed nuclei (IN) of the intermediate cerebellum are critical components of the circuits that control associative learning of eyeblinks and other defensive reflexes in mammals. The IN, which represent the sole output of the intermediate cerebellum, receive massive GABAergic input from Purkinje cells of the ce...

journal_title：Brain research

authors： Parker KL,Zbarska S,Carrel AJ,Bracha V

更新日期：2009-10-06 00:00:00

abstract：:Regeneration of crushed axons in rat dorsal spinal roots was measured to investigate the transganglionic influence of an additional peripheral axonal injury. The right sciatic nerve was cut at the hip and the left sciatic nerve was left intact. One week later, both fifth lumbar dorsal roots were crushed and subsequent...

journal_title：Brain research

authors： Richardson PM,Verge VM

更新日期：1987-05-19 00:00:00

abstract：:Small injections of two highly sensitive anterograde tracers, Phaseolus vulgaris-leucoagglutinin (PHA-L) and biocytin, into the striatum and the subthalamic nucleus of squirrel monkeys (Saimiri sciureus) have revealed a high degree of convergence of striatal and subthalamic fibers upon single pallidal cells. Both affe...

journal_title：Brain research

authors： Hazrati LN,Parent A

更新日期：1992-01-13 00:00:00

abstract：:Dynorphin and other kappa opioid agonists are thought to elicit aversive actions and changes in motor activity through direct or indirect modulation of dopamine neurons in ventral tegmental area (VTA) and substantia nigra (SN), respectively. We comparatively examined the immunoperoxidase localization of anti-dynorphin...

journal_title：Brain research

authors： Pickel VM,Chan J,Sesack SR

更新日期：1993-02-05 00:00:00

abstract：:Carbonic anhydrase (CA) and cholinesterase (CE) histochemical staining of rabbit spinal nerve roots and dorsal root ganglia demonstrated that among the reactive myelinated axons, with minor exceptions, sensory axons were CA positive and CE negative whereas motor axons were CA negative and CE positive. The high specifi...

journal_title：Brain research

authors： Riley DA,Sanger JR,Matloub HS,Yousif NJ,Bain JL,Moore GH

更新日期：1988-06-21 00:00:00

abstract：:We studied seizures which were induced by a microinjection of kainic acid (KA) into the unilateral olfactory bulb (OB) in the rats. The first epileptiform discharge appeared in the OB, was then propagated to the amygdala and the hippocampus unilaterally, and finally propagated to the unilateral sensori-motor cortex. C...

journal_title：Brain research

authors： Araki T,Kato M,Kobayashi T

更新日期：1995-09-25 00:00:00

abstract：:While moderate calorie restriction (CR) in the absence of malnutrition has been consistently shown to have a systemic, beneficial effect against aging in several animals models, its effect on the brain microstructure in a non-human primate model remains to be studied using post-mortem histopathologic techniques. In th...

journal_title：Brain research

authors： Sridharan A,Pehar M,Salamat MS,Pugh TD,Bendlin BB,Willette AA,Anderson RM,Kemnitz JW,Colman RJ,Weindruch RH,Puglielli L,Johnson SC

更新日期：2013-05-01 00:00:00

abstract：:About 45% of the serotonergic raphe neurons are reported to express nerve growth factor (NGF) receptors. We therefore investigated whether selective serotonergic lesions of the median or dorsal raphe nuclei are associated with changes in NGF protein levels of the brain and whether the loss of serotonergic function alt...

journal_title：Brain research

authors： Hellweg R,Thomas H,Arnswald A,von Richthofen S,Kay S,Fink H,Morgenstern R,Hörtnagl H

更新日期：2001-07-13 00:00:00

abstract：:Brief applications of high glycine concentrations to hippocampal slices have been shown to produce long-lasting changes in synaptic efficacy. In the present study, we show that glycine application transiently and reversibly increases the amplitude and prolongs the duration of synaptic potentials mediated by N-methyl-D...

journal_title：Brain research

authors： Shahi K,Baudry M

更新日期：1993-11-12 00:00:00

abstract：:Toxoplasma gondii can cause parasitic encephalitis, a life-threatening infection that predominately occurs in immunocompromised individuals. T. gondii has the ability to invade the brain, but the mechanisms by which this parasite crosses the blood-brain-barrier (BBB) remain incompletely understood. The present study r...

journal_title：Brain research

authors： Harun MSR,Marsh V,Elsaied NA,Webb KF,Elsheikha HM

更新日期：2020-11-01 00:00:00

abstract：:Intracellular transport of newly synthesized proteins through organelles in the perikarya of regenerating goldfish retinal ganglion cells was studied using electron microscopic autoradiography. Retinas were removed 14 or 30 days after optic tract cut or sham operation, pulse-labeled in [3H]proline-containing medium fo...

journal_title：Brain research

authors： Whitnall MH,Grafstein B

更新日期：1982-05-06 00:00:00

abstract：:Activation of kappa-opioid receptors (KOR) in the medial prefrontal cortex (mPFC) modulates excitatory transmission, which may involve interactions with N-methyl-D-aspartate (NMDA) glutamate receptors. We investigated possible anatomical correlates of this modulation by using dual labeling electron microscopy to exami...

journal_title：Brain research

authors： Svingos AL,Colago EE

更新日期：2002-08-16 00:00:00

abstract：:The postnatal development of the terminal Schwann cell, an analogue of the lamellar cell in cutaneous sensory receptors, was examined by histochemistry for non-specific cholinesterase and immunohistochemistry for S-100 protein in the periodontal Ruffini endings of the rat incisor. Double immunohistochemistry for S-100...

journal_title：Brain research

authors： Hayashi S,Nakakura-Ohshima K,Ohshima H,Noda T,Honma S,Wakisaka S,Maeda T

更新日期：2000-03-06 00:00:00

abstract：:Strychnine-sensitive, inhibitory glycine receptors have not until lately been considered to play a significant role in neurotransmission in mammalian forebrain regions. In order to investigate the role of glycine as a neurotransmitter in brain we have measured glycine induced chloride fluxes in different adult rat for...

journal_title：Brain research

authors： Engblom AC,Eriksson KS,Akerman KE

更新日期：1996-03-11 00:00:00

abstract：:Degeneration of noradrenergic neurons in the locus coeruleus (LC) and dysfunction of the prefrontal cortex were regarded as playing a specific role in the occurrence of non-motor symptoms in Parkinson's disease. The present study examined the spontaneous firing rate and firing pattern of medial prefrontal cortex (mPFC...

journal_title：Brain research

authors： Wang Y,Zhang QJ,Liu J,Ali U,Gui ZH,Hui YP,Wang T,Chen L,Li Q

更新日期：2010-04-09 00:00:00

abstract：:Patients with sickle cell disease (SCD) can develop strokes and as a result, present neurologic and neurocognitive deficits. However, recent studies show that even without detectable cerebral parenchymal abnormalities on imaging studies, SCD patients can have significant cognitive and motor dysfunction, which can pres...

journal_title：Brain research

authors： Almeida LEF,Wang L,Kamimura S,Zerfas PM,Smith ML,Neto OLA,Vale T,Quezado MM,Horkayne-Szakaly I,Wakim P,Quezado ZMN

更新日期：2020-11-01 00:00:00

abstract：:Experiments were carried out to determine if stimuli which augment preganglionic nerve activity to sympathetic neurons, and thereby cause trans-synaptic induction, increase the retrograde transport of nerve growth factor (NGF). It was found that nerve activity had no effect on retrograde transport of [125I]NGF. It was...

journal_title：Brain research

authors： Johnson EM Jr,Blumberg HM,Costrini NV,Bradshaw RA

更新日期：1979-12-14 00:00:00

abstract：:Measurements of extracellular Ca2+ and K+ activities [( Ca2+]o, [K+]o) in the superfused cat carotid body in vitro with triple-barrelled ion-selective electrodes have shown that hypoxia induced a decrease in [Ca2+]o of 0.035 +/- 0.17 mM (mean +/- S.D.; n = 17) and a biphasic change in [K+]o which consisted of an incre...

journal_title：Brain research

authors： Delpiano MA,Acker H

更新日期：1989-03-20 00:00:00

abstract：:In nondiabetic animals, estrogen has been shown to provide significant neuroprotection in focal and transient forebrain ischemia models. However, that neuroprotection may be diminished or lost in the diabetic. In this study, we compared the level of brain damage in intact, ovariectomized (OVX) and 17beta-estradiol (E(...

journal_title：Brain research

authors： Santizo RA,Xu HL,Ye S,Baughman VL,Pelligrino DA

更新日期：2002-11-22 00:00:00

abstract：:It is well known that the nerve growth factor (NGF) may serve as a link between inflammation and hyperalgesia. Recent experiments showed that systemic injection of NGF dramatically stimulated the expression of brain-derived neurotrophic factor (BDNF) mRNA in the dorsal root ganglion (DRG). In the present study, we eva...

journal_title：Brain research

authors： Cho HJ,Kim SY,Park MJ,Kim DS,Kim JK,Chu MY

更新日期：1997-02-28 00:00:00

abstract：:To evaluate the role of the amygdala in pain modulation and opioid-mediated antinociception, a recombinant, replication-defective herpes virus carrying the human preproenkephalin cDNA was injected bilaterally into the rat amygdala. Four days after gene delivery nociceptive behavior was assessed by the formalin test. R...

journal_title：Brain research

authors： Kang W,Wilson MA,Bender MA,Glorioso JC,Wilson SP

更新日期：1998-05-04 00:00:00

abstract：:The present experiments were performed to demonstrate in vivo the existence of a modulatory role of Na+ in the inhibitory control of prolactin (PRL) secretion. Groups of adult male rats were either adrenalectomized (adrenex) or sham-operated (normals) and implanted in the right atrium with a chronic cannula for the in...

journal_title：Brain research

authors： Collu R,Bouvier C

更新日期：1987-01-13 00:00:00

abstract：:This study investigates the effects of levetiracetam (LEV) on the functional and structural properties of blood-brain barrier (BBB) in pentylenetetrazole (PTZ)-kindled rats with cortical dysplasia (CD). Pregnant rats were exposed to 145 cGy of gamma-irradiation on embryonic day 17. In offsprings, kindling was induced ...

journal_title：Brain research

authors： Gurses C,Ekizoglu O,Orhan N,Ustek D,Arican N,Ahishali B,Elmas I,Kucuk M,Bilgic B,Kemikler G,Kalayci R,Karadeniz A,Kaya M

更新日期：2009-07-24 00:00:00

abstract：:In behaving cats, a cholinergic agonist, carbachol, or Ringer's solution were infused into the pontine reticular formation (PRF). Extracellular microelectrode recordings were obtained from single neurons located 1-4 mm from the infusion site. Sleep polygraphic variables were also recorded. Carbachol microinfusions int...

journal_title：Brain research

authors： Shiromani PJ,McGinty DJ

更新日期：1986-10-29 00:00:00

abstract：:Calretinin has been identified as a brain specific calcium-binding protein which appears as a prominent protein in the cochlear nucleus. We identified and localized calretinin in the guinea pig and rat inner ear using polyclonal antibodies. Immunoblot analyses of guinea pig and rat auditory nerve homogenates revealed ...

journal_title：Brain research

authors： Dechesne CJ,Winsky L,Kim HN,Goping G,Vu TD,Wenthold RJ,Jacobowitz DM

更新日期：1991-09-27 00:00:00

abstract：:The effects of glucagon like peptide-1 (GLP-1) on reflex swallowing were examined using anaesthetized rats. GLP-1 was injected into the dorsal vagal complex (DVC) using glass micropipettes. Swallowing was induced by repeated electrical stimulation of the central cut end of the superior laryngeal nerve (SLN) and was id...

journal_title：Brain research

authors： Kobashi M,Mizutani S,Fujita M,Mitoh Y,Shimatani Y,Matsuo R

更新日期：2017-09-15 00:00:00

abstract：:This study tested the effect on intracranially injected cycloheximide (CHX), an inhibitor of protein synthesis, on facilitation of sexual receptivity in ovariectomized rats. The rats received 0.5 microgram estradiol benzoate (EB), s.c. once daily on days 8 through 12 after ovariectomy (OVX). Either CHX (in 0.5 microli...

journal_title：Brain research

authors： Renner KJ,Bast JD,Purcell ES,Quadagno DM

更新日期：1981-10-19 00:00:00

abstract：:The development of spontaneous activity in response to morphine administration was studied at different postnatal ages in C57BL/6 mice. Morphine induced hyperactivity at all ages except in 3-week-old mice, in which a catatonic effect is evident. The results indicate that the neurophysiological and inhibitory systems r...

journal_title：Brain research

authors： Filibeck U,Castellano C,Oliverio A

更新日期：1981-11-01 00:00:00