Antibacterial and antifungal activities of some Mexican medicinal plants.

Abstract:

:In Mexico about 4,000 plant species have some medicinal use. The aim of this work was to evaluate the antimicrobial activity of six Mexican medicinal plants against fungi and Gram-positive and Gram-negative bacteria. Methanolic extracts were prepared from the Mexican medicinal plants Amphypteringium adstrigens, Castella tortuosa, Coutarea latiflora, Ibervillea sonorae, Jatropha cuneata, and Selaginella lepidophylla. The antibacterial and antifungal activities of the plants were determined by the broth microdilution method and the radial growth inhibition assay, respectively. All Mexican plants tested showed antimicrobial activity. Among the six plant extracts analyzed, J. cuneata showed the highest growth-inhibitory activity against fungi, Gram-positive and Gram-negative bacteria (J. cuneata > A. adstrigens > C. latiflora > C. tortuosa > I. sonorae approximately S. lepidophylla). Shigella flexneri and Staphylococcus aureus were the most susceptible bacteria to plant extracts. Complete inhibition of S. flexneri growth was observed with J. cuneata methanolic extract at 90 microg/mL. This plant extract also showed the strongest antifungal activity against Fusarium verticillioides and Aspergillus niger. Our data suggest that the medicinal plants tested have important antimicrobial properties. This is the first report describing the antimicrobial activities of several of the Mexican medicinal plants used in this study.

journal_name

J Med Food

authors

Ruiz-Bustos E,Velazquez C,Garibay-Escobar A,García Z,Plascencia-Jatomea M,Cortez-Rocha MO,Hernandez-Martínez J,Robles-Zepeda RE

doi

10.1089/jmf.2008.0205

subject

Has Abstract

pub_date

2009-12-01 00:00:00

pages

1398-402

issue

6

eissn

1096-620X

issn

1557-7600

journal_volume

12

pub_type

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