Symptom severity and distress in advanced cancer.

Abstract:

:We determined the relationship between symptom severity and distress for multiple cancer symptoms, and examined patient demographic influences on severity and distress in advanced cancer. A Cochran-Armitage trend test determined whether symptom distress increased with severity. Chi-square, Fisher's exact test and logistic regression analysis examined moderate/severe ('clinically important') and distressful symptoms by age (65), gender, primary site group, and ECOG performance status. Forty-six symptoms were analyzed in 181 individuals. More than 50% of individuals with clinically important symptoms rated them as distressful. The median percentage of individuals with mild but still distressful symptoms was 25%, with a range of 0% (bad dreams) to 73% (sore mouth). In both univariate and multivariate analysis, younger (

journal_name

Palliat Med

journal_title

Palliative medicine

authors

Kirkova J,Walsh D,Rybicki L,Davis MP,Aktas A,Tao Jin,Homsi J

doi

10.1177/0269216309356380

subject

Has Abstract

pub_date

2010-04-01 00:00:00

pages

330-9

issue

3

eissn

0269-2163

issn

1477-030X

pii

0269216309356380

journal_volume

24

pub_type

杂志文章
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