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Antineoplastic activities of protein-conjugated silver sulfide nano-crystals with different shapes.

Abstract：

:In this paper, antineoplastic activities of protein-conjugated silver sulfide nano-crystals with different shapes were described in detail. Transmission electron microscope analysis demonstrated that stable and well-disperse protein-conjugated silver sulfide nano-particles, nano-rods, and nano-wires could be prepared by aqueous chemistry method. The Fourier transform infrared spectrograph analysis indicated the strong coordination between silver sulfide surfaces and -OH and -NH groups in bovine serum albumin. The antineoplastic activities of protein-conjugated silver sulfide nano-crystals were examined by cell viability analysis, optical and electron microscopy methods. The results showed that nano-particles, nano-rods and nano-wires could inhibit the proliferations of human hepatocellular carcinoma Bel-7402 cells and C6 glioma cells, and the activities were size-dependent.

journal_name

J Inorg Biochem

journal_title

Journal of inorganic biochemistry

authors

Wang HJ,Yang L,Yang HY,Wang K,Yao WG,Jiang K,Huang XL,Zheng Z

doi

10.1016/j.jinorgbio.2009.10.015

subject

Has Abstract

pub_date

2010-01-01 00:00:00

pages

87-91

issue

1

eissn

0162-0134

issn

1873-3344

pii

S0162-0134(09)00263-3

journal_volume

104

pub_type

杂志文章

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