Binding ability of Cu2+ ions by opiate-like fragments of bovine casein.

abstract：:The strength of inhibition of beta-hematin (synthetic hemozoin or malaria pigment) formation by the quinoline antimalarial drugs chloroquine, amodiaquine, quinidine and quinine has been investigated as a function of incubation time. In the assay used, beta-hematin formation was brought about using 4.5M acetate, pH 4.5...

journal_title：Journal of inorganic biochemistry

authors： Egan TJ,Ncokazi KK

更新日期：2005-07-01 00:00:00

abstract：:The solution structure of Fe(II)-peplomycin was determined from NMR data collected for this molecule. As found previously for Fe(II)- and Co(II)-bound bleomycin; the coordination sphere of the metal is composed of the primary and secondary amines in β-aminoalanine, the pyrimidine and imidazole rings in the pyrimidinyl...

journal_title：Journal of inorganic biochemistry

authors： Li Y,Lehmann T

更新日期：2012-06-01 00:00:00

abstract：:Incubation of cytochrome c oxidase (CcO) in its resting state in saturated ammonium sulfate, at room temperature overnight, gave EPR signals characteristic of a single Cu(II) center. From the g// and A// values it is concluded that this is a square-planar type 2 copper center, and superhyperfine splitting shows the pr...

journal_title：Journal of inorganic biochemistry

authors： Pezeshk A,Torres J,Wilson MT,Symons MC

更新日期：2001-01-15 00:00:00

abstract：:We have studied the electron paramagnetic resonance (epr) spectra of complexes of apo-yeast enolase with 65Cu+2 in the presence and absence of substrate and magnesium ion. An unusual epr spectrum with large g parallel, large g and A rhombicity and very narrow line-widths (10 G) is seen for the first two 65Cu+2 bound i...

journal_title：Journal of inorganic biochemistry

authors： Dickinson LC,Rose SL,Westhead EW

更新日期：1980-12-01 00:00:00

abstract：:Nanosized polyphosphazene-platinum (II) conjugates with a wide range of molecular weight from 24,000 to 115,000 were synthesized to study their tumor selectivity by enhanced permeability and retention (EPR) effect and their antitumor activity. It has been found from biodistribution study that the present polyphosphaze...

journal_title：Journal of inorganic biochemistry

authors： Jun YJ,Kim JI,Jun MJ,Sohn YS

更新日期：2005-08-01 00:00:00

abstract：:The magnetic properties of intact and freeze-dried blood cells of the tunicate Ascidia nigra and of model vanadium(III) and (IV) compounds as polycrystalline solids and in aqueous solution have been measured up to 50 kOe with a SQUID susceptometer. Corrections for the samples' diamagnetism were extracted from the temp...

journal_title：Journal of inorganic biochemistry

authors： Lee S,Kustin K,Robinson WE,Frankel RB,Spartalian K

更新日期：1988-07-01 00:00:00

abstract：:Laser-induced Eu(3+) luminescence spectroscopy is used to probe the interaction of Eu(3+) ion with guanine-containing nucleotides and single-stranded oligomers. By using time-resolved and non-time-resolved Eu(3+) luminescence techniques, two classes of Eu(3+) binding site are observed in oligo(dG)10, oligo(dG)8, oligo...

journal_title：Journal of inorganic biochemistry

authors： Klakamp SL,Horrocks WD Jr

更新日期：1992-05-15 00:00:00

abstract：:Composites of beta-chitin with calcium carbonate polymorphs were prepared by precipitation of the mineral into a chitin scaffold by means of a double diffusion system. The beta-chitin was obtained from the pen of the Loligo sp. squid. The three main polymorphs of calcium carbonate: aragonite, calcite and vaterite, wer...

journal_title：Journal of inorganic biochemistry

authors： Falini G,Fermani S,Ripamonti A

更新日期：2002-08-30 00:00:00

abstract：:[Ru(bzimpy)(2)]Cl(2), where bzimpy is 2,6-bis(benzimidazol-2-yl) pyridine was synthesized and characterized by ESI-MS, UV-Visible, (1)H NMR and fluorescence spectra. Absorption titration and thermal denaturation experiments indicate that the complex binds to DNA with moderate strength. Viscosity measurement shows that...

journal_title：Journal of inorganic biochemistry

authors： Vaidyanathan VG,Nair BU

更新日期：2002-08-15 00:00:00

abstract：:Multicopper oxidases (MCO) are the fastest and most efficient known catalysts of the oxygen-reduction reaction. When all four copper ions are oxidized during catalysis, the native intermediate state (NI) decays in seconds to the resting oxidized state (RO), which returns to the catalytic cycle via reduction, but at a ...

journal_title：Journal of inorganic biochemistry

authors： Machczynski MC,Babicz JT Jr

更新日期：2016-06-01 00:00:00

abstract：:The reaction mechanism of the oxidation of 2,6-dichlorophenol (2,6-DCP) by horseradish peroxidase (HRP) and H2O2 has been investigated and the reaction products have been characterized by UV-visible and mass spectrometry. Evidence for the dimerization of 2,6-DCP to 3,3',5,5'-tetrachloro-4,4'-dihydroxybiphenyl and the ...

journal_title：Journal of inorganic biochemistry

authors： Laurenti E,Ghibaudi E,Todaro G,Pia Ferrari R

更新日期：2002-09-30 00:00:00

abstract：:Fe(III)-salen (N,N-bis(salicylidene)-ethane-1,2-diimine) complexes of simple hydroxamic acids and the MMP (matrix metalloproteinase) inhibitor marimastat have been evaluated as hypoxia activated drug carriers. The aceto- (aha), propion- (pha), benzohydroxamato (bha), and marimastat complexes were prepared and characte...

journal_title：Journal of inorganic biochemistry

authors： Failes TW,Hambley TW

更新日期：2007-03-01 00:00:00

abstract：:With the aim to investigate the mechanism of Cu(I) transport by Wilson ATPase (ATP7B), we have studied the interaction of the peptides 2K10p (CH(3)CO-Lys-Gly-Met-Thr-Cys-Ala-Ser-Cys-Val-His-Asn-Lys-CONH(2)), and 2K8p (CH(3)CO-Lys-Leu-Cys-Ile-Ala-Cys-Pro-Cys-Ser-Lys-CONH(2)), part of the sixth metal binding domain (WD6...

journal_title：Journal of inorganic biochemistry

authors： Myari A,Hadjiliadis N,Fatemi N,Sarkar B

更新日期：2004-09-01 00:00:00

abstract：:The biochemical characterization of individual nitrergic (NO releasing) neurons is a non-trivial task both in vertebrate and invertebrate preparations. In spite of numerous efforts, there are limited data related to intracellular concentrations of essential metabolites involved in NO synthesis and degradation. This si...

journal_title：Journal of inorganic biochemistry

authors： Moroz LL,Dahlgren RL,Boudko D,Sweedler JV,Lovell P

更新日期：2005-04-01 00:00:00

abstract：:The chemical structures of Ru (II) complexes are known to affect their cellular behavior and toxicity. In this study, three new luminescent Ru (II) complexes, [Ru(bpy)2(HIPMP)](ClO4)2 (Ru1, bpy = 2,2'-bipyridine, HIPMP = 2-(1H-imidazo-[4,5-f] [1,10] phenanthrolin-2-yl)-4-methylphenol), [Ru(phen)2(HIPMP)](ClO4)2 (Ru2, ...

journal_title：Journal of inorganic biochemistry

authors： Xu L,Zhang PP,Fang XQ,Liu Y,Wang JQ,Zhou HZ,Chen ST,Chao H

更新日期：2019-02-01 00:00:00

abstract：:Three-week-old Picea abies seedlings were grown for 7 days in 100 microM aluminium (Al), combined with 1000 or 2000 microM silicon (Si). Solution pH was adjusted to 4.00, 4.25, 4.50, 4.75, or 5.00. In the absence of Si, solution pH had no effect on the decrease in root growth caused by 100 microM Al. Silicon did not a...

journal_title：Journal of inorganic biochemistry

authors： Ryder M,Gérard F,Evans DE,Hodson MJ

更新日期：2003-09-15 00:00:00

abstract：:The effect of the lanthanide(III) complexes [Gd(1,4,7,10-tetraazacyclododecane-N,N',N", N"'-tetrakis(methylenephosphonate))]5- (Gd-DOTP) and La-DOTP on the oxygen binding and spectroscopic properties of human adult and fetal hemoglobin (HbA and HbF, respectively) has been investigated. The affinity of Gd-DOTP and La-D...

journal_title：Journal of inorganic biochemistry

authors： Aime S,Fasano M,Paoletti S,Bellelli A,Coletta M,Ascenzi P

更新日期：1998-08-01 00:00:00

abstract：:Nearly all microbes require iron for growth. The low concentration of iron found in the ocean makes iron acquisition a particularly difficult task. In response to these low iron conditions, many bacteria produce low-molecular-weight iron-binding molecules called siderophores to aid in iron uptake. We report herein the...

journal_title：Journal of inorganic biochemistry

authors： Gauglitz JM,Zhou H,Butler A

更新日期：2012-02-01 00:00:00

abstract：:Selenium is an essential trace element for humans and other animals, and there is mounting evidence for the efficacy of certain forms of selenium as cancer-chemopreventive compounds. However, over the years, numerous elements such as As, Cu, Zn, Cd, Hg, Sn, Pb, Ni, Co, Sb, Bi, Ag, Au, and Mo have been found to inhibit...

journal_title：Journal of inorganic biochemistry

authors： Zeng H,Uthus EO,Combs GF Jr

更新日期：2005-06-01 00:00:00

abstract：:Polyamines are ubiquitous polycations that participate in cellular processes such as growth, differentiation and cell death. Among the different functions ascribed to these organic cations, the polyamine spermine is known to protect DNA from the damage produced by reactive oxygen species (ROS) generated by different a...

journal_title：Journal of inorganic biochemistry

authors： Pedreño E,López-Contreras AJ,Cremades A,Peñafiel R

更新日期：2005-10-01 00:00:00

abstract：:Bacteria have developed multiple resistance mechanisms against the most used antibiotics. In particular, zinc-dependent metallo-β-lactamase producing bacteria are a growing threat, and therapeutic options are limited. Zinc chelators have recently been investigated as metallo-β-lactamase inhibitors, as they are often a...

journal_title：Journal of inorganic biochemistry

authors： La Piana L,Viaggi V,Principe L,Di Bella S,Luzzaro F,Viale M,Bertola N,Vecchio G

更新日期：2021-02-01 00:00:00

abstract：:The amyloidogenic peptide amylin is found associated with pancreatic islet beta-cells and is implicated in the aetiology of type-2 diabetes mellitus. We have used fluorimetry and transmission electron microscopy to investigate in vitro the influence of Al(III), Fe(III), Zn(II) and Cu(II) on amylin amyloid formation un...

journal_title：Journal of inorganic biochemistry

authors： Ward B,Walker K,Exley C

更新日期：2008-02-01 00:00:00

abstract：:Nine recombinant FixL heme domains from Bradyrhizobium japonicum previously were shown to exhibit mass instability independent of many environmental factors (J.D. Satterlee, C. Suquet, A. Bidwai, J. Erman, L. Schwall, R. Jimenez, Biochemistry 47 (2008) 1540-1553). Two of those recombinant proteins were produced in rem...

journal_title：Journal of inorganic biochemistry

authors： Satterlee JD

更新日期：2011-05-01 00:00:00

abstract：:The new potential antitumour soluble drug K[Ru(eddp)Cl(2)].3H(2)O, (eddp=ethylenediamine-N,N'-di-3-propionate) has been isolated and characterized. The analysis of the interaction of this complex with pBR322 plasmid DNA by circular dichroism spectroscopy shows that the ruthenium complex initially induces alteration of...

journal_title：Journal of inorganic biochemistry

authors： Grguric-Sipka SR,Vilaplana RA,Pérez JM,Fuertes MA,Alonso C,Alvarez Y,Sabo TJ,González-Vílchez F

更新日期：2003-10-01 00:00:00

abstract：:Four different-anion Ag(I) compounds with the ligand norharmane (9H-Pyrido[3,4-b]indole; Hnor) and having the general formula [Ag(Hnor)2](anion) (anion=ClO4(-), NO3(-) and BF4(-)) [Ag(Hnor)2(MeCN)](PF6) are reported, and studied in detail regarding their coordination mode and in vitro antiproliferative effects. X-ray ...

journal_title：Journal of inorganic biochemistry

authors： Ahmad Khan R,Al-Farhan K,de Almeida A,Alsalme A,Casini A,Ghazzali M,Reedijk J

更新日期：2014-11-01 00:00:00

abstract：:Vanadium compounds exert various insulin-mimetic and anti-diabetic effects both in vitro and in vivo. Vanadium(III, IV, V)-chlorodipicolinate (Vdipic-Cl) compounds, including H[V(III)(dipic-Cl)2]·5H2O (V3dipic-Cl), V(IV)O(dipic-Cl)(H2O)2 (V4dipic-Cl) and K[V(V)O2(dipic-Cl)] (V5dipic-Cl), were synthesized with the indi...

journal_title：Journal of inorganic biochemistry

authors： Xie M,Chen D,Zhang F,Willsky GR,Crans DC,Ding W

更新日期：2014-07-01 00:00:00

abstract：:The new cyclic tetrapeptide c(HGHK) was synthesised in the solid phase and its complexes with copper(II) were studied in aqueous solution at various pH values by means of potentiometric and spectroscopic methods (UV, EPR, CD). Six mononuclear coordination species were clearly identified within the pH range 3-11. Spect...

journal_title：Journal of inorganic biochemistry

authors： Brasun J,Gabbiani C,Ginanneschi M,Messori L,Orfei M,Swiatek-Kozlowska J

更新日期：2004-12-01 00:00:00

abstract：:The antitumoral potential for a series of platinum iodido complexes, all bearing the same aliphatic amines (first iodido complexes generation), was demonstrated in a previous study. Concretely, cis complexes were shown to have a peculiar and different reactivity compared to cisplatin with sulfur donors models and Cyt ...

journal_title：Journal of inorganic biochemistry

authors： Parro T,Medrano MA,Cubo L,Muñoz-Galván S,Carnero A,Navarro-Ranninger C,Quiroga AG

更新日期：2013-10-01 00:00:00

abstract：:Human neuronal growth inhibitory factor (GIF) is a metallothionein-like protein specific to the central nervous system, which has been linked to Alzheimer's disease. In this article a short overview of the biological and structural properties of native Cu4,Zn3-GIF are described. Moreover, metal-thiolate clusters forme...

journal_title：Journal of inorganic biochemistry

authors： Vasák M,Hasler DW,Faller P

更新日期：2000-04-01 00:00:00

abstract：:The study of possible relationships between iron and vanadium metabolism (E. Sabbioni and E. Marafante, Proc. XIth Int. Conf. Biochem., 13-5-R122, Toronto, Canada) was extended to the vanadium in the biochemical mechanisms which involve the exchange of iron between transferrin and ferritin. The transfer of vanadium be...

journal_title：Journal of inorganic biochemistry

authors： Sabbioni E,Rade J,Bertolero F

更新日期：1980-07-01 00:00:00