Synthesis, characterization and DNA binding studies of a ruthenium(II) complex.

abstract：:A series of new 3d metal complexes with 5-chloro-quinolin-8-ol (ClQ), [Mn(ClQ)2] (1), [Fe(ClQ)3] (2), [Co(ClQ)2(H2O)2] (3), [Ni(ClQ)2(H2O)2] (4), [Cu(ClQ)2] (5), [Zn(ClQ)2(H2O)2] (6), [Mn(ClQ)3]·DMF (7) and [Co(ClQ)3]·DMF·(EtOH)0.35 (8) (DMF=N,N-dimethylformamide), has been synthesized and characterized by elemental a...

journal_title：Journal of inorganic biochemistry

authors： Potočňák I,Vranec P,Farkasová V,Sabolová D,Vataščinová M,Kudláčová J,Radojević ID,Čomić LR,Markovic BS,Volarevic V,Arsenijevic N,Trifunović SR

更新日期：2016-01-01 00:00:00

abstract：:The complexation between tin(II) ion and glycine was studied in 0.15 mol/dm3 NaCl medium at 310 K using potentiometric glass electrode titrations. In the pH range 1.1-4.5 and concentration range of the tin(II) between 0.2 and 5.0 mmol/dm3, with variable glycine-to-tin molar ratio up to 10:1, the experimental data were...

journal_title：Journal of inorganic biochemistry

authors： Djurdjevic P,Djokic D

更新日期：1996-04-01 00:00:00

abstract：:Aiming at tumor targeting delivery of oxaliplatin using polymer therapy, a new monomeric platinum(II) complex (dach)Pt[HEDM] (dach: trans-(±)-1,2-diaminocyclohexane; HEDM: 2-hydroxyethoxydiethylmalate) was designed to include the antitumor moiety (dach)Pt and HEDM as a linker to the polyphosphazene backbone. This mono...

journal_title：Journal of inorganic biochemistry

authors： Avaji PG,Joo HI,Park JH,Park KS,Jun YJ,Lee HJ,Sohn YS

更新日期：2014-11-01 00:00:00

abstract：:HIF prolyl-4-hydroxylase 2 (PHD2) is a non-heme Fe, 2-oxoglutarate (2OG) dependent dioxygenase that regulates the hypoxia inducible transcription factor (HIF) by hydroxylating two conserved prolyl residues in N-terminal oxygen degradation domain (NODD) and C-terminal oxygen degradation domain (CODD) of HIF-1α. Prior s...

journal_title：Journal of inorganic biochemistry

authors： Pektas S,Knapp MJ

更新日期：2013-09-01 00:00:00

abstract：:Three-week-old Picea abies seedlings were grown for 7 days in 100 microM aluminium (Al), combined with 1000 or 2000 microM silicon (Si). Solution pH was adjusted to 4.00, 4.25, 4.50, 4.75, or 5.00. In the absence of Si, solution pH had no effect on the decrease in root growth caused by 100 microM Al. Silicon did not a...

journal_title：Journal of inorganic biochemistry

authors： Ryder M,Gérard F,Evans DE,Hodson MJ

更新日期：2003-09-15 00:00:00

abstract：:Prochloron, a blue-green algae belonging to ancient prokaryotes, produces, like other cyanobacteria, cyclic pseudo-peptides, which are also found in its obligate symbiont ascidiae (Lissoclinum patellum). Although research has focused for some time on the putative metabolic function of these cyclic peptides, to date it...

journal_title：Journal of inorganic biochemistry

authors： Comba P,Eisenschmidt A,Kipper N,Schießl J

更新日期：2016-06-01 00:00:00

abstract：:This work describes in situ synthesis and application of the zinc glutamate Bio Metal-Organic Framework (BioMOF) supported on cellulose fabrics as a dual material for nitric oxide (NO) and 5-fluorouracil (5FU) controlled delivery for wound and/or skin cancer therapy. In situ synthesis of BioMOF on the cotton fabric wa...

journal_title：Journal of inorganic biochemistry

authors： Noorian SA,Hemmatinejad N,Navarro JAR

更新日期：2019-12-01 00:00:00

abstract：:In order to investigate the low-dose long-term Cr(VI) action on antioxidant enzymes in cultured mammalian cells we estimated the activity of glutathione dependent antioxidant enzymes, catalase and superoxide dismutase (SOD) under various chromium concentrations in human epithelial-like L-41 cells. The long-term action...

journal_title：Journal of inorganic biochemistry

authors： Asatiani N,Sapojnikova N,Abuladze M,Kartvelishvili T,Kulikova N,Kiziria E,Namchevadze E,Holman HY

更新日期：2004-03-01 00:00:00

abstract：:As two quite complicated substances, arsenic (As) and copper (Cu) have polluted to the environment. As is highly toxic and could cause nerve damage. Cu is involved in the occurrence of oxidative stress. The brain is one of the main target organs of heavy metal toxicity, but the damage mechanism activated by As and/or ...

journal_title：Journal of inorganic biochemistry

authors： Liu Y,Zhao H,Wang Y,Guo M,Mu M,Xing M

更新日期：2020-10-01 00:00:00

abstract：:Bioorganometallic ferrocene-dipeptide conjugates with the Ala-Pro-cysteamine chain, Fc-L-Ala-L-Pro-NHCH2CH2SH (2) and Fc-L-Ala-D-Pro-NHCH2CH2SH (4) (Fc=ferrocenoyl), were prepared by the reduction of the ferrocene-dipeptide conjugates, Fc-L-Ala-L-Pro-cystamine-L-Pro-L-Ala-Fc (1) or Fc-L-Ala-D-Pro-cystamine-D-Pro-L-Ala...

journal_title：Journal of inorganic biochemistry

authors： Moriuchi T,Nishiyama T,Tayano Y,Hirao T

更新日期：2017-12-01 00:00:00

abstract：:Cultured rat hepatoma cells (HTC-cells) were used to study the transfer of copper from a well-defined medium to and across the cell membrane and particularly the role of albumin in this process. HTC-cells, maintained in a minimal salt-glucose medium, accumulated far more copper than when maintained in the same medium,...

journal_title：Journal of inorganic biochemistry

authors： van den Berg GJ,van den Hamer CJ

更新日期：1984-10-01 00:00:00

abstract：:The antiproliferative properties of a series of structurally-related gold(I) and silver(I) linear complexes inspired to the clinically established gold-based drug auranofin were investigated in A2780 ovarian cancer cells and in their auranofin (A2780/AF-R) and cisplatin (A2780/CDDP-R) resistant counterparts. In A2780 ...

journal_title：Journal of inorganic biochemistry

authors： Landini I,Massai L,Cirri D,Gamberi T,Paoli P,Messori L,Mini E,Nobili S

更新日期：2020-07-01 00:00:00

abstract：:Five Ru(II)(η6-toluene) complexes formed with 2-picolinic acid and its various derivatives have been synthesized and characterized. X-ray structures of four complexes are also reported. Complex formation processes of [Ru(II)(η6-toluene)(H2O)3]2+ organometallic cation with the metal-free ligands were studied in aqueous...

journal_title：Journal of inorganic biochemistry

authors： Poljarević JM,Tamás Gál G,May NV,Spengler G,Dömötör O,Savić AR,Grgurić-Šipka S,Enyedy ÉA

更新日期：2018-04-01 00:00:00

abstract：:Two-subunit SoxB-type cytochrome c oxidase in Bacillus stearothermophilus was over-produced, purified, and examined for its active site structures by electron paramagnetic resonance (EPR) and resonance Raman (RR) spectroscopies. This is cytochrome bo3 oxidase containing heme B at the low-spin heme site and heme O at t...

journal_title：Journal of inorganic biochemistry

authors： Uchida T,Tsubaki M,Kurokawa T,Hori H,Sakamoto J,Kitagawa T,Sone N

更新日期：2000-11-01 00:00:00

abstract：:A comparative study of the Cu2+ effects, binding and reduction, has been performed on rat liver mitochondria. In the first minutes, Cu2+ (less than or equal to 50 micron) is massively bound and reduced to the extent of 70%-80% while a simultaneous activation of respiration takes place. Then the remaining 20% or so of ...

journal_title：Journal of inorganic biochemistry

authors： Leblondel G,Allain P

更新日期：1984-07-01 00:00:00

abstract：:A range of phosphorescent Ir(III) complexes containing four diverse P^P-chelating ligands of the type [Ir(ppy)2(L)][PF6], (ppy = 2‑phenylpyridine) where L is 1,2‑bis(diphenylphosphino)benzene (L1), 1,2‑bis(diphenylphosphino)ethane (L2), 1,2‑bis(diphenylphosphino)propane(L3) and 1,8‑bis(diphenylphosphino)naphthalene (L...

journal_title：Journal of inorganic biochemistry

authors： Liu Z,Li J,Ge X,Zhang S,Xu Z,Gao W

更新日期：2019-08-01 00:00:00

abstract：:Oxyhemoglobin is oxidized to methemoglobin by copper(II) in a two-stage reaction that results in conversion of Fe(II) to Fe(III) in heme of the beta subunits, but not the alpha subunits. Glutathione and other thiols, which are slowly oxidized by Cu(II), protect oxyhemoglobin from Cu(II)-induced oxidation. In the prese...

journal_title：Journal of inorganic biochemistry

authors： Smith RC,Reed VD,Webb TR

更新日期：1993-11-15 00:00:00

abstract：:Copper(II) complexes with the non-steroidal anti-inflammatory drug diflunisal in the presence of N,N-dimethylformamide or nitrogen donor heterocyclic ligands (pyridine, 1,10-phenanthroline, 2,2'-bipyridine or 2,2'-bipyridylamine) have been synthesized and characterized. The deprotonated diflunisal ligands are coordina...

journal_title：Journal of inorganic biochemistry

authors： Fountoulaki S,Perdih F,Turel I,Kessissoglou DP,Psomas G

更新日期：2011-12-01 00:00:00

abstract：:Electron paramagnetic resonance (e.p.r.) studies of thin DNA-chelate films indicate that both the water soluble planar macrocyclic chelates, cobalt (II) tetra (2,3-N-methylpyridinium) porphyrazine (cobalt (II) TMTPPA), and vanadyl (II) 5,10,15,20-tetra-(4-methylpyridinium) porphyrin (Vo (II) TMTPyP) can bind to calf t...

journal_title：Journal of inorganic biochemistry

authors： Dougherty G

更新日期：1988-10-01 00:00:00

abstract：:Ruthenium complexes hold a great potential in chemotherapy as an alternative to the classical platinum based drugs. The organometallic compounds studied in the present work were previously found to exhibit important anticancer activities. Here we have investigated the binding of three ruthenium compounds, namely [Ru(η...

journal_title：Journal of inorganic biochemistry

authors： Morais TS,Santos FC,Corte-Real L,Garcia MH

更新日期：2013-12-01 00:00:00

abstract：:The complexation of uranium(VI) to variant functional groups of the highly phosphorylated protein phosvitin in aqueous solution was investigated by attenuated total reflection Fourier transform infrared (ATR FT-IR) spectroscopy. For the verification of the affinity of the actinyl ions to carboxyl and phosphate groups ...

journal_title：Journal of inorganic biochemistry

authors： Li B,Raff J,Barkleit A,Bernhard G,Foerstendorf H

更新日期：2010-07-01 00:00:00

abstract：:Mechanistic pathways underlying inflammatory injury following exposures to vanadium-containing compounds are not defined. We tested the postulate that the in vitro biological effect of vanadium results from its impact on iron homeostasis. Human bronchial epithelial (HBE) cells exposed to vanadyl sulfate (VOSO4) showed...

journal_title：Journal of inorganic biochemistry

authors： Ghio AJ,Stonehuerner J,Soukup JM,Dailey LA,Kesic MJ,Cohen MD

更新日期：2015-06-01 00:00:00

abstract：:The stability constants of the mixed ligand complexes formed between Cu(Arm)2+, where Arm=2,2'-bipyridine (Bpy) or 1,10-phenanthroline (Phen), and the monoanion or the dianion of 9-(4-phosphonobutyl)adenine (dPMEA=3'-deoxa-PMEA), which is the carba analogue of the antivirally active 9-[2-(phosphonomethoxy)ethyl]adenin...

journal_title：Journal of inorganic biochemistry

authors： Gómez-Coca RB,Kapinos LE,Holý A,Vilaplana RA,González-Vílchez F,Sigel H

更新日期：2001-03-01 00:00:00

abstract：:Phosphate buffer suspensions of unilamellar liposomes of phosphatidylcholine were irradiated with UVC (254 nm) and UVB (300 nm) light. The irradiation provoked lipid peroxidation and liposome lysis with release of entrapped glucose-6-phosphate. At the same intensity of absorbed light, the photochemical effect at 254 n...

journal_title：Journal of inorganic biochemistry

authors： Costanzo LL,De Guidi G,Giuffrida S,Sortino S,Condorelli G

更新日期：1995-07-01 00:00:00

abstract：:Heme oxygenase (HO) catalyses the degradation of heme to biliverdin, carbon monoxide (CO) and ferrous iron via three successive monooxygenase reactions, using electrons provided by NADPH-cytochrome P450 reductase (CPR) and oxygen molecules. For cleavage of the oxaporphyrin ring of ferrous α-verdoheme, an intermediate ...

journal_title：Journal of inorganic biochemistry

authors： Sato H,Higashimoto Y,Sakamoto H,Sugishima M,Shimokawa C,Harada J,Palmer G,Noguchi M

更新日期：2011-02-01 00:00:00

abstract：:The [Cu(sulfathiazolato)(2)(benzimidazole)(2)]2MeOH complex has been synthesised and characterised. It crystallises in the monoclinic system, space group C1c1, with unit cell dimensions a=18.829(7) A, b=12.206(3) A, c=17.233(5) A, alpha=90.06(2) degrees, beta=97.28(3) degrees, gamma=90.21(3) degrees and Z=4. The geome...

journal_title：Journal of inorganic biochemistry

authors： González-Alvarez M,Alzuet G,Borrás J,Macías B,del Olmo M,Liu-González M,Sanz F

更新日期：2002-04-10 00:00:00

abstract：:Folic acid is degraded by cytochrome c in the presence of hydrogen peroxide/tert-butyl hydroperoxide at the C9-N10 bond. The degradation is increased with increasing temperature. When guanidine HCl or benzoate are included in the reaction medium, the amount of folic acid degradation is enhanced. Catalase, formate, and...

journal_title：Journal of inorganic biochemistry

authors： Taher MM,Lakshmaiah N

更新日期：1987-10-01 00:00:00

abstract：:Neuroglobin is a monomeric globin containing a six-coordinate heme b, expressed in the nervous system, which exerts an important neuroprotective role. In the human protein (hNgb), Cys46 and Cys55 form an intramolecular disulfide bond under oxidizing conditions, whose cleavage induces a helix-to-strand rearrangement of...

journal_title：Journal of inorganic biochemistry

authors： Bellei M,Bortolotti CA,Di Rocco G,Borsari M,Lancellotti L,Ranieri A,Sola M,Battistuzzi G

更新日期：2018-01-01 00:00:00

abstract：:Solution behavior of levofloxacin (lvx) complexes with copper(II) in the presence and absence of phen was studied in aqueous solution, by potentiometry. The results obtained show that under physiological conditions (micromolar concentration range and pH 7.4) only copper(II):lvx:phen ternary complexes are stable. Hence...

journal_title：Journal of inorganic biochemistry

authors： Sousa I,Claro V,Pereira JL,Amaral AL,Cunha-Silva L,de Castro B,Feio MJ,Pereira E,Gameiro P

更新日期：2012-05-01 00:00:00

abstract：:Bis[platinum(II)] [Cl2Pt(LL)PtCl2] complexes 2,5 and 8 with chiral non-racemic ligands: 1a-c (LL = (R,R), (S,S) and (R,S) N,N'-bis(3,4-diaminobutyl)hexanediamide); 4a,b (LL = (R,R) and (S,S) N,N'-bis[3,4-bis(diaminobutyl)] urea); 7a-d (LL' = (R,R), (S,S), (R,S) and (S,R) 4,5-diamino-N-(3,4-diaminobutyl) pentanamide) a...

journal_title：Journal of inorganic biochemistry

authors： Büning H,Altman J,Zorbas H,Beck W

更新日期：1999-07-15 00:00:00