Abstract：
:Phosphate buffer suspensions of unilamellar liposomes of phosphatidylcholine were irradiated with UVC (254 nm) and UVB (300 nm) light. The irradiation provoked lipid peroxidation and liposome lysis with release of entrapped glucose-6-phosphate. At the same intensity of absorbed light, the photochemical effect at 254 nm is higher than at 300 nm. The addition of copper(II) and manganese(II) reduced both the peroxidation and the lysis. The copper showed an inhibitory effect only on the process provoked by the 254 nm irradiation, whereas the manganese was efficient both at 254 and 300 nm. The results are interpreted with a mechanism of peroxidation and quenching, involving photoformation of peroxyl radicals that are scavenged by manganese(II) and copper(I), with consequent breaking of the radical chain and reduction of the peroxidation rate. The copper(I), which is the active species, can be formed only at 254 nm by electron capture. The experimental data fit the kinetic equations obtained by the proposed mechanism by means of computer software.
journal_name
J Inorg Biochemjournal_title
Journal of inorganic biochemistryauthors
Costanzo LL,De Guidi G,Giuffrida S,Sortino S,Condorelli Gdoi
10.1016/0162-0134(94)00048-fsubject
Has Abstractpub_date
1995-07-01 00:00:00pages
1-13issue
1eissn
0162-0134issn
1873-3344pii
016201349400048Fjournal_volume
59pub_type
杂志文章abstract：:The reactions of hydroquinone with hydrogen peroxide catalyzed by transition metal ions Cu2+, Fe2+, Fe3+, Co2+ and Mn2+ were investigated in aqueous solution at 25 degrees C. Two copper (II) complexes (bis(dimethylglyoxime) copper(II) and 5,7,7,12,14,14-hexamethyl-1,4,8,11-tetraazacyclotetradeca-4,11-dienatocopper(II)...
journal_title：Journal of inorganic biochemistry
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journal_title：Journal of inorganic biochemistry
pub_type： 杂志文章
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journal_title：Journal of inorganic biochemistry
pub_type： 杂志文章
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journal_title：Journal of inorganic biochemistry
pub_type： 杂志文章
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journal_title：Journal of inorganic biochemistry
pub_type： 杂志文章
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更新日期：2015-11-01 00:00:00
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pub_type： 杂志文章
doi：10.1016/j.jinorgbio.2012.10.005
更新日期：2013-01-01 00:00:00
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journal_title：Journal of inorganic biochemistry
pub_type： 杂志文章
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journal_title：Journal of inorganic biochemistry
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journal_title：Journal of inorganic biochemistry
pub_type： 杂志文章
doi：10.1016/j.jinorgbio.2016.11.007
更新日期：2017-01-01 00:00:00
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journal_title：Journal of inorganic biochemistry
pub_type： 杂志文章
doi：10.1016/j.jinorgbio.2013.01.011
更新日期：2013-05-01 00:00:00
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journal_title：Journal of inorganic biochemistry
pub_type： 杂志文章
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更新日期：2013-01-01 00:00:00
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journal_title：Journal of inorganic biochemistry
pub_type： 杂志文章
doi：10.1016/j.jinorgbio.2015.12.011
更新日期：2016-03-01 00:00:00
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journal_title：Journal of inorganic biochemistry
pub_type： 杂志文章
doi：10.1016/s0162-0134(97)00030-5
更新日期：1997-11-01 00:00:00
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journal_title：Journal of inorganic biochemistry
pub_type： 杂志文章
doi：10.1016/j.jinorgbio.2004.10.022
更新日期：2005-02-01 00:00:00
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journal_title：Journal of inorganic biochemistry
pub_type： 杂志文章
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pub_type： 杂志文章
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更新日期：2005-03-01 00:00:00
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journal_title：Journal of inorganic biochemistry
pub_type： 杂志文章
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更新日期：2009-05-01 00:00:00
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journal_title：Journal of inorganic biochemistry
pub_type： 杂志文章
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更新日期：2011-01-01 00:00:00
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journal_title：Journal of inorganic biochemistry
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更新日期：2012-12-01 00:00:00
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更新日期：2018-12-01 00:00:00
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pub_type： 杂志文章
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更新日期：1983-11-01 00:00:00
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更新日期：2020-03-01 00:00:00
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journal_title：Journal of inorganic biochemistry
pub_type： 杂志文章
doi：10.1016/j.jinorgbio.2009.12.015
更新日期：2010-05-01 00:00:00
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journal_title：Journal of inorganic biochemistry
pub_type： 杂志文章
doi：10.1016/j.jinorgbio.2011.11.014
更新日期：2012-02-01 00:00:00
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journal_title：Journal of inorganic biochemistry
pub_type： 杂志文章
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更新日期：1985-11-01 00:00:00
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journal_title：Journal of inorganic biochemistry
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更新日期：2020-09-01 00:00:00
