Insertion and 3-year follow-up experience of 372 etonogestrel subdermal contraceptive implants by family physicians in Granada, Spain.

Abstract:

BACKGROUND:User profile, continuation rate, reasons for discontinuation, problems during insertion and removal, and effectiveness of an etonogestrel subdermal contraceptive implant (ESCI) were assessed. STUDY DESIGN:A follow-up of 372 women 3 years after insertion of an ESCI performed by family physicians in Granada, Spain, by means of consultations, examination of medical records and telephone interviews. RESULTS:Data were available for 356 (95.7%) women. The average age was 27.2 years, and 159 (42.7%) were nulliparous. Continuation rates were 91.0% at 1 year, 74.7% at 2 years and 65.1% at 2 years and 9 months. The main reasons for discontinuation were excessive bleeding (44, 12.4%), wish to become pregnant (44, 12.4%) and side effects not related to menstruation (21, 5.9%). However, 141 (39.6%) received a second implant when the first one expired. No pregnancy occurred in 893.4 women-years. CONCLUSIONS:Family physicians can achieve excellent results with the ESCI. It should be included in the range of contraceptives offered by primary care physicians.

journal_name

Contraception

journal_title

Contraception

authors

Arribas-Mir L,Rueda-Lozano D,Agrela-Cardona M,Cedeño-Benavides T,Olvera-Porcel C,Bueno-Cavanillas A

doi

10.1016/j.contraception.2009.04.003

subject

Has Abstract

pub_date

2009-11-01 00:00:00

pages

457-62

issue

5

eissn

0010-7824

issn

1879-0518

pii

S0010-7824(09)00118-8

journal_volume

80

pub_type

杂志文章
  • Termination of early pregnancy (menstrual induction) with 16-phenoxy-omega-tetranor PGE2 methylsulfonylamide.

    abstract::The efficacy and side effects of a new synthetic compound, 16-phenoxy-W-17, 18, 19, 20-tetranor prostaglandin E2 methylsulfonylamide, for menstrual induction. The study was conducted in an outpatient clinic in 240 patients with a delay in menstruation of 6-14 days. In 206 patients (86%) the immunologic pregnancy tes...

    journal_title:Contraception

    pub_type: 杂志文章

    doi:10.1016/0010-7824(77)90049-x

    authors: Karim SM,Rao B,Ratnam SS,Prasad RN,Wong YM,Ilancheran A

    更新日期:1977-10-01 00:00:00

  • Exploring young women's decisional needs for contraceptive method choice: a qualitative study.

    abstract:OBJECTIVE:Assisting women with choosing contraceptive methods that meet their needs and preferences is essential to providing patient-centered care, but research to inform interventions supporting method choice is lacking. An assessment of patient decisional needs for contraceptive method choice may provide insight int...

    journal_title:Contraception

    pub_type: 杂志文章

    doi:10.1016/j.contraception.2017.10.004

    authors: Marshall C,Kandahari N,Raine-Bennett T

    更新日期:2018-03-01 00:00:00

  • Factors associated with contraceptive nonuse among US women ages 35-44 years at risk of unwanted pregnancy.

    abstract:BACKGROUND:Women ages 35 years and older have the greatest proportion of contraceptive nonuse and unintended pregnancies ending in abortion. STUDY DESIGN:We conducted a population-based case-control study among women ages 35-44 years at risk of unwanted pregnancy using the National Survey of Family Growth (NSFG) data ...

    journal_title:Contraception

    pub_type: 杂志文章

    doi:10.1016/j.contraception.2009.12.013

    authors: Upson K,Reed SD,Prager SW,Schiff MA

    更新日期:2010-05-01 00:00:00

  • Domestic violence against women seeking induced abortion in China.

    abstract::A cross-sectional study was conducted to investigate the prevalence, type and severity of domestic violence (DV), and determine the factors related to DV among women seeking induced abortion in China. A total of 1215 women seeking induced abortion were interviewed. The results show that the prevalence of DV among part...

    journal_title:Contraception

    pub_type: 杂志文章

    doi:10.1016/j.contraception.2005.02.010

    authors: Wu J,Guo S,Qu C

    更新日期:2005-08-01 00:00:00

  • Long-term effect of low-dose combined steroid contraceptives on body iron status.

    abstract::The present study was aimed to evaluate iron metabolism in active and healthy adult women having taken oral contraceptives (OC) long-term. Mean dietary iron intake in age-matched control and experimental groups was adequate. Serum ferritin used as a marker for body iron stores was marginal in both groups underlying a ...

    journal_title:Contraception

    pub_type: 杂志文章

    doi:10.1016/0010-7824(92)90005-e

    authors: Massé PG,Roberge AG

    更新日期:1992-09-01 00:00:00

  • A pharmacokinetic and pharmacodynamic study of a 'visiting pill' containing norethisterone.

    abstract::The pharmacokinetics and pharmacodynamic effects of two doses of norethisterone (5mg and 3mg) used as a 'visiting pill' were investigated. There were no significant differences in the pharmacokinetics of the two doses except for the peak concentration achieved and the bioavailability as assessed by the area under the ...

    journal_title:Contraception

    pub_type: 杂志文章

    doi:10.1016/0010-7824(86)90008-9

    authors: Song S,Chen JK,Yang PJ,Cheng DH,Liu WY,Fotherby K

    更新日期:1986-09-01 00:00:00

  • Can mifepristone medical abortion be simplified? A review of the evidence and questions for future research.

    abstract::Mifepristone medical abortion has been a valuable addition to the reproductive health options of women. Aspects of its provision have however sometimes limited its accessibility and use. This article summarizes existing evidence for simplifying the provision of medical abortion and thus increasing its availability. We...

    journal_title:Contraception

    pub_type: 杂志文章,评审

    doi:10.1016/j.contraception.2006.11.011

    authors: Clark WH,Gold M,Grossman D,Winikoff B

    更新日期:2007-04-01 00:00:00

  • Etonogestrel implant migration to the vasculature, chest wall, and distant body sites: cases from a pharmacovigilance database.

    abstract:OBJECTIVE:To describe clinical outcomes of etonogestrel implant patients with migration to the vasculature, chest wall and other distant body sites spontaneously reported to the US Food and Drug Administration Adverse Event Reporting System (FAERS) database. STUDY DESIGN:We performed a standardized Medical Dictionary ...

    journal_title:Contraception

    pub_type: 杂志文章

    doi:10.1016/j.contraception.2017.08.009

    authors: Kang S,Niak A,Gada N,Brinker A,Jones SC

    更新日期:2017-12-01 00:00:00

  • Inhibition of glycolysis in boar sperm by alpha-chlorohydrin.

    abstract::The effect of alpha-chlorohydrin (3-chloropropan-1,2-diol) on the metabolism of D-[U-14C]-fructose and L-[U-14C]-lactate by washed boar sperm has been investigated. Whereas alpha-chlorohydrin at concentrations as low as 0.1 mM inhibited the metabolism of fructose and led to an increase in the utilization of endogenous...

    journal_title:Contraception

    pub_type: 杂志文章

    doi:10.1016/0010-7824(80)90103-1

    authors: Hutton P,Dawson AG,Jones AR

    更新日期:1980-11-01 00:00:00

  • Evaluation of shorter mifepristone to misoprostol intervals for second trimester medical abortion: a retrospective cohort study.

    abstract:OBJECTIVES:To assess shorter mifepristone-misoprostol intervals compared to current guidelines for second trimester medical abortion on total abortion time (mifepristone to fetal expulsion) and induction time (first misoprostol to fetal expulsion). METHODS:This retrospective cohort study included women who elected for...

    journal_title:Contraception

    pub_type: 杂志文章

    doi:10.1016/j.contraception.2020.06.009

    authors: Henkel A,Lerma K,Blumenthal PD,Shaw KA

    更新日期:2020-11-01 00:00:00

  • Adolescent contraceptive use and its determinants in Bangladesh: evidence from Bangladesh Fertility Survey 1989.

    abstract::This study is concerned with contraceptive use among the currently married adolescents in Bangladesh utilizing the 1989 Bangladesh Fertility Survey (BFS) data. The study analyzes the factors affecting the current use of contraception among the adolescents through bivariate and multivariate logistic regression analysis...

    journal_title:Contraception

    pub_type: 杂志文章

    doi:10.1016/0010-7824(95)00149-5

    authors: Mahmud M,Islam MM

    更新日期:1995-09-01 00:00:00

  • Efficacy of fennel and combined oral contraceptive on depot medroxyprogesterone acetate-induced amenorrhea: a randomized placebo-controlled trial.

    abstract:OBJECTIVES:We aimed to determine the efficacy of fennel and low-dose combined oral contraceptive (LD-COC) on inducing menstrual bleeding and method continuation in women using depot medroxyprogesterone acetate (DMPA) who had no menstrual bleeding within the previous 45 to 140 days. STUDY DESIGN:In this double-blind do...

    journal_title:Contraception

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.contraception.2014.05.001

    authors: Mohebbi-Kian E,Mohammad-Alizadeh-Charandabi S,Bekhradi R

    更新日期:2014-10-01 00:00:00

  • Evaluation of one-hundred open-ended vasectomies.

    abstract::Open-ended vasectomy was performed on one-hundred men. Sixty-three of them showed up for follow-up six months later. Spontaneous recanalisation had occurred in two. Sperm granuloma without orchialgia was found in 14 out of 59 men (23.9%). Twenty-one out of the 63 thought their sex life had improved, while 40 thought i...

    journal_title:Contraception

    pub_type: 杂志文章

    doi:10.1016/0010-7824(86)90040-5

    authors: Temmerman M,Cammu H,Devroey P,Amy JJ

    更新日期:1986-06-01 00:00:00

  • The anti-glycolytic activity of 3-bromopyruvate on mature boar spermatozoa in vitro.

    abstract::Mature epididymal boar spermatozoa converted fructose, glycerol and glycerol-3-phosphate to carbon dioxide, but in the presence of 0.5 mM 3-bromopyruvate, these oxidations were inhibited while that of lactate was unaffected. Inhibition of the oxidation of these substrates results in a decrease in the content of ATP an...

    journal_title:Contraception

    pub_type: 杂志文章

    doi:10.1016/0010-7824(95)00217-x

    authors: Jones AR,Gillan L,Milmlow D

    更新日期:1995-11-01 00:00:00

  • Changes in lipoprotein composition in women receiving two low-dose oral contraceptives containing ethinylestradiol and gonane progestins.

    abstract::In a prospective double-blind study of the effects of two low-dose oral contraceptives (OCs) on lipid and lipoprotein metabolism, two groups of eighteen young healthy women selected at random were submitted to a six months' use of either monophasic ethinylestradiol (EE) + desogestrel (DG) or triphasic EE + levonorgest...

    journal_title:Contraception

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/0010-7824(88)90003-0

    authors: Harvengt C,Desager JP,Gaspard U,Lepot M

    更新日期:1988-06-01 00:00:00

  • Worldwide use of intrauterine contraception: a review.

    abstract:BACKGROUND:Globally, 14.3% of women of reproductive age use intrauterine contraception (IUC), but the distribution of IUC users is strikingly nonuniform. In some countries, the percentage of women using IUC is <2%, whereas in other countries, it is >40%. Reasons for this large variation are not well documented. The aim...

    journal_title:Contraception

    pub_type: 杂志文章,评审

    doi:10.1016/j.contraception.2013.11.011

    authors: Buhling KJ,Zite NB,Lotke P,Black K,INTRA Writing Group.

    更新日期:2014-03-01 00:00:00

  • Vaginal misoprostol for late first trimester abortion.

    abstract::A group of 120 women with gestations from 64 to 84 days received 800 micrograms of vaginal misoprostol every 24 h for a maximum of three doses without performing postexpulsion systematic preventive curettage. Outcome measures included successful abortion (complete abortion without requiring a surgical procedure), side...

    journal_title:Contraception

    pub_type: 杂志文章

    doi:10.1016/s0010-7824(98)00037-7

    authors: Carbonell Esteve JL,Varela L,Velazco A,Cabezas E,Tanda R,Sánchez C

    更新日期:1998-05-01 00:00:00

  • Early induction of abortion by a combination of oral mifepristone and misoprostol administered by the vaginal route.

    abstract::Medically induced abortion using a new regimen of oral mifepristone 600 mg and vaginal misoprostol 800 micrograms (PGE1 analogue) was carried out in 100 women. Abortion occurred in all patients without resort to surgery. In 99 women, the abortion occurred within 4 hours of the administration of the prostaglandin. Sixt...

    journal_title:Contraception

    pub_type: 杂志文章

    doi:10.1016/0010-7824(94)90085-x

    authors: el-Refaey H,Templeton A

    更新日期:1994-02-01 00:00:00

  • Intraoperative placement of the Copper T-380 intrauterine devices in women undergoing elective cesarean delivery: a pilot study.

    abstract:BACKGROUND:The purpose of this pilot project was to test the feasibility of a technique designed to place a copper intrauterine device (IUD) through the hysterotomy incision of an elective cesarean delivery to minimize possible contamination and to guarantee that tailstrings were visible in the vagina for easy removal ...

    journal_title:Contraception

    pub_type: 杂志文章

    doi:10.1016/j.contraception.2009.01.014

    authors: Nelson AL,Chen S,Eden R

    更新日期:2009-07-01 00:00:00

  • Study on the factors associated with contraceptive discontinuations in Bangkok.

    abstract::Detailed information was collected from 666 cohorts of pill, injectable-DMPA and IUD acceptors at 14 Bangkok Metropolis Health Clinics (MHCs). The contraceptive status at 12-month follow-up home interview shows that 47% of pill acceptors, 39% of DMPA acceptors and 55% of IUD acceptors were still using the same contrac...

    journal_title:Contraception

    pub_type: 杂志文章

    doi:10.1016/s0010-7824(84)80004-9

    authors: Chumnijarakij T,Sunyavivat S,Onthuam Y,Udomprasertgul V

    更新日期:1984-03-01 00:00:00

  • Contraceptive use among women with cystic fibrosis: A pilot study linking reproductive health questions to the Cystic Fibrosis Foundation National Patient Registry.

    abstract:OBJECTIVES:To examine contraceptive use, pregnancy intention and the association of hormonal contraceptive type with adverse health outcomes among women with cystic fibrosis (CF). STUDY DESIGN:We recruited 150 women with CF, ages 18-49 from three adult CF programs to complete an online survey regarding their pregnancy...

    journal_title:Contraception

    pub_type: 杂志文章

    doi:10.1016/j.contraception.2020.02.006

    authors: Godfrey EM,Mody S,Schwartz MR,Heltshe SL,Taylor-Cousar JL,Jain R,Sufian S,Josephy T,Aitken ML

    更新日期:2020-06-01 00:00:00

  • Medroxyprogesterone acetate and estradiol cypionate injectable suspension (Cyclofem) monthly contraceptive injection: steady-state pharmacokinetics.

    abstract:BACKGROUND:Cyclofem is a combined injectable contraceptive, containing medroxyprogesterone acetate (MPA) and estradiol cypionate. The objective was to characterize the steady-state pharmacokinetics (PK) using tandem liquid chromatography/mass spectrometry and compare these data to a previous PK study of this formulatio...

    journal_title:Contraception

    pub_type: 杂志文章

    doi:10.1016/j.contraception.2012.11.010

    authors: Thurman A,Kimble T,Hall P,Schwartz JL,Archer DF

    更新日期:2013-06-01 00:00:00

  • Latex rubber condoms: predicting and extending shelf life.

    abstract::Condoms from five manufacturers were subjected to controlled exposures of heat, humidity, and air and to different natural environments in five countries. Under aerobic conditions (condoms in permeable packages or unpackaged), stress properties declined. The relationship between rate of decline as a function of temper...

    journal_title:Contraception

    pub_type: 杂志文章

    doi:10.1016/0010-7824(96)00041-8

    authors: Free MJ,Srisamang V,Vail J,Mercer D,Kotz R,Marlowe DE

    更新日期:1996-04-01 00:00:00

  • Women's motivation to participate in contraceptive efficacy trials.

    abstract:BACKGROUND:We sought to determine whether there are differences in subject's motivation to participate in hormonal and barrier method contraceptive efficacy studies. STUDY DESIGN:All women presenting for screening appointments for either barrier or hormonal contraceptive efficacy trials were asked to complete a survey...

    journal_title:Contraception

    pub_type: 杂志文章

    doi:10.1016/j.contraception.2009.03.015

    authors: Hohmann H,Reid L,Creinin MD

    更新日期:2009-09-01 00:00:00

  • Release kinetics of 3-keto-desogestrel from contraceptive implants (Implanon) in dogs: comparison with in vitro data.

    abstract::Ethylene-vinyl acetate (EVA) polymeric contraceptive implants (Implanon) containing 3-keto-desogestrel have been prepared aiming at an in vitro initial release rate of 60 micrograms 3-keto-desogestrel/day. These implants are designed to have an intended life-time of 2 years. During a 3-year period, the release of thes...

    journal_title:Contraception

    pub_type: 杂志文章

    doi:10.1016/0010-7824(93)90093-m

    authors: Geelen JA,van der Wardt JT,Voortman G,Maassen GC,Eenink MJ

    更新日期:1993-02-01 00:00:00

  • Contraceptive use at last intercourse among reproductive-aged women with disabilities: an analysis of population-based data from seven states.

    abstract:OBJECTIVE:To assess patterns of contraceptive use at last intercourse among women with physical or cognitive disabilities compared to women without disabilities. STUDY DESIGN:We analyzed responses to 12 reproductive health questions added by seven states to their 2013 Behavioral Risk Factor Surveillance System questio...

    journal_title:Contraception

    pub_type: 杂志文章

    doi:10.1016/j.contraception.2017.12.008

    authors: Haynes RM,Boulet SL,Fox MH,Carroll DD,Courtney-Long E,Warner L

    更新日期:2018-06-01 00:00:00

  • Influence of copper ions on uterine activity.

    abstract::The influence of copper ions on myometrial activity was tested in nonpregnant rabbits in vitro and in vivo, and nonpregnant women in vivo. In an organ bath, CuCl2 in concentrations of 3 micro M and higher caused a dose-dependent increase in the contractile activity of isolated rabbit myometrium. In rabbits in vivo, in...

    journal_title:Contraception

    pub_type: 杂志文章

    doi:10.1016/0010-7824(81)90092-5

    authors: Laundański T,Kobylec E,Akerlund M

    更新日期:1981-08-01 00:00:00

  • Progestin-only pill use and pill switching during breastfeeding.

    abstract::The opinions of 20 international experts in reproductive endocrinology and family planning service delivery were solicited concerning contraceptive pill use during breastfeeding and, in particular, to determine whether the experts felt that breastfeeding women who use progestin-only pills (POPs) should be advised to s...

    journal_title:Contraception

    pub_type: 社论

    doi:10.1016/0010-7824(95)00076-m

    authors: Visness CM,Rivera R

    更新日期:1995-05-01 00:00:00

  • Kinetics of bromhexine-mediated down-regulation of focal adhesive molecules of uterus and trophectoderm affecting conception in the rat.

    abstract:PURPOSE:Quantitative evaluation of properties of bromhexine (B) for expression of uterine proteins in ovariectomized (OVX) and pregnant rats. MATERIALS AND METHODS:Expression of proteins through SDS-PAGE, along with incorporation of glycosidic moieties, was conducted in pregnant and OVX rats under B influence. These f...

    journal_title:Contraception

    pub_type: 杂志文章

    doi:10.1016/j.contraception.2005.11.006

    authors: Singh N,Malaviya B

    更新日期:2006-06-01 00:00:00

  • Oral contraceptives and venous thromboembolism: should epidemiologic associations drive clinical decision making?

    abstract::New studies linking use of oral contraceptives (OCs) containing a third generation progestogen with venous thromboembolism (VTE) have stirred controversy. Epidemiologists face the task of separating a direct effect of the OC from the confounding effect of a pre-existing factor (e.g., smoking). Only 1-2% of VTE cases...

    journal_title:Contraception

    pub_type: 评论,社论

    doi:10.1016/0010-7824(96)00111-4

    authors: Westhoff CL

    更新日期:1996-07-01 00:00:00