Long-term effect of low-dose combined steroid contraceptives on body iron status.


:The present study was aimed to evaluate iron metabolism in active and healthy adult women having taken oral contraceptives (OC) long-term. Mean dietary iron intake in age-matched control and experimental groups was adequate. Serum ferritin used as a marker for body iron stores was marginal in both groups underlying a high prevalence of deficient-iron reserves among subjects. This parameter was not correlated to the iron content of the diet. The serum iron concentration was significantly higher in OC users than control subjects (p less than 0.001). Biochemical results commanded a discussion on the pertinence of evaluating the total dietary iron intake and on the sensitivity of biochemical methods used to assess the iron status.






Massé PG,Roberge AG




Has Abstract


1992-09-01 00:00:00














  • Effect of temperature and pH on contraceptive gel viscosity.

    abstract::The rheological properties of four commercially available spermicidal gels (two polyacrylic acid derivatives and two carboxymethylcellulose based) and their dilutions with a vaginal fluid simulant (pH 4.2) and a semen simulant (pH 7.7) were measured at 25 degrees C and 37 degrees C over a biologically relevant range o...


    pub_type: 杂志文章


    authors: Owen DH,Peters JJ,Lavine ML,Katz DF

    更新日期:2003-01-01 00:00:00

  • Development and evaluation of matrix type transdermal patch of ethinylestradiol and medroxyprogesterone acetate for anti-implantation activity in female Wistar rats.

    abstract:BACKGROUND:Medroxyprogesterone acetate (MPA), which increases high-density lipoprotein level, has not been used as a progestin in combination with estrogen in a transdermal patch to date. The aim of the research was to develop and evaluate a matrix-type transdermal drug delivery (TDD) system of a combination of ethinyl...


    pub_type: 杂志文章


    authors: Agrawal SS,Pruthi JK

    更新日期:2011-11-01 00:00:00

  • Cervical preparation for second-trimester surgical abortion prior to 20 weeks' gestation: SFP Guideline #2013-4.

    abstract::For a dilation and evacuation (D&E) procedure, the cervix must be dilated sufficiently to allow passage of operative instruments and products of conception without injuring the uterus or cervical canal. Preoperative preparation of the cervix reduces the risk of cervical laceration and uterine perforation. The cervix m...


    pub_type: 杂志文章,实务指引


    authors: Fox MC,Krajewski CM

    更新日期:2014-02-01 00:00:00

  • Emergency contraception in Jordan: Assessing retail pharmacists' awareness, opinions, and perceptions of need.

    abstract:OBJECTIVES:Jordan has a robust contraceptive method mix in both the public and private sectors and oral contraceptive pills and the copper-T intrauterine device are widely available. However, Jordan remains one of only a few countries in the world without a registered dedicated product for emergency contraception (EC)....


    pub_type: 杂志文章


    authors: El-Mowafi IM,Foster AM

    更新日期:2020-04-01 00:00:00

  • Midtrimester abortion with intramuscular injection of 15-methyl-prostaglandin F2alpha.

    abstract::This study examines the efficacy and side effects of 15-methyl-prostaglandins F2alpha (PGF2a) free acid administered intramuscularly for midtrimester abortion. 50 healthy women aged 14 to 37 years and between 12 to 18 weeks gestation were randomly selected from the abortion clinic at the Los Angeles County/USC Medica...


    pub_type: 杂志文章


    authors: Slaughter L,Ballard CA

    更新日期:1975-05-01 00:00:00

  • The short-term effects of a low-dose oral contraceptive on glucose metabolism, plasma lipids and blood clotting factors.

    abstract::Twelve young women were prospectively evaluated for the short-term metabolic effects of a low-dose oral contraceptive containing 30 micrograms ethinyl estradiol and 150 micrograms levonorgestrel. To each volunteer a 50 g glucose challenge was administered monthly as a screening test for changes in the glucose metaboli...


    pub_type: 杂志文章


    authors: Skouby SO,Wagner HH,Andersen O

    更新日期:1983-11-01 00:00:00

  • The anti-glycolytic activity of 3-bromopyruvate on mature boar spermatozoa in vitro.

    abstract::Mature epididymal boar spermatozoa converted fructose, glycerol and glycerol-3-phosphate to carbon dioxide, but in the presence of 0.5 mM 3-bromopyruvate, these oxidations were inhibited while that of lactate was unaffected. Inhibition of the oxidation of these substrates results in a decrease in the content of ATP an...


    pub_type: 杂志文章


    authors: Jones AR,Gillan L,Milmlow D

    更新日期:1995-11-01 00:00:00

  • Severity of infection following the introduction of new infection control measures for medical abortion.

    abstract:BACKGROUND:In response to concerns about serious infections following medical abortion, in early 2006 the Planned Parenthood Federation of America changed the route of misoprostol administration from vaginal to buccal and required either routine antibiotic coverage or universal screening and treatment for chlamydia; in...


    pub_type: 杂志文章


    authors: Fjerstad M,Trussell J,Lichtenberg ES,Sivin I,Cullins V

    更新日期:2011-04-01 00:00:00

  • Inhibition by gossypol of cyclic AMP production in mouse Leydig cells.

    abstract::Gossypol has been shown to inhibit steroidogenesis in leydig cells. This study examined the mechanism of this action by investigating the effect of gossypol on leydig cell hCG receptor binding, adenylate cyclase activity and cyclic AMP production in leydig cells. Gossypol had no effect on hCG binding to cell membranes...


    pub_type: 杂志文章


    authors: Pearce S,Sufi SB,O'Shaughnessy PJ,Donaldson A,Jeffcoate SL

    更新日期:1986-12-01 00:00:00

  • Management and localization strategies for the nonpalpable Implanon rod.

    abstract:PURPOSE:The goal of this paper is to review the imaging methods required for localizing nonpalpable Implanontrade mark. METHOD:Different localization methods for nonpalpable Implanon rods are summarized, and clinical guidance is provided as to how best to localize such implants. RESULTS:In the great majority of cases...


    pub_type: 杂志文章,评审


    authors: Shulman LP,Gabriel H

    更新日期:2006-04-01 00:00:00

  • Impact of tubal ligation on ovarian reserve as measured by anti-Müllerian hormone levels: a prospective cohort study.

    abstract:BACKGROUND:Tubal ligation (TL) is considered a very efficient contraceptive method. However, some patients complain of a variety of postoperative symptoms. The objective of this study was to investigate whether ovarian reserve may change after tubal ligation. STUDY DESIGN:This was a prospective cohort study of 80 fert...


    pub_type: 杂志文章


    authors: Silva AL,Ré Cd,Dietrich C,Fuhrmeister IP,Pimentel A,Corleta HV

    更新日期:2013-12-01 00:00:00

  • Follicular development in a 7-day versus 4-day hormone-free interval with an oral contraceptive containing 20 mcg ethinyl estradiol and 1 mg norethindrone acetate.

    abstract:BACKGROUND:Combined oral contraceptive (COC) formulations with 20 mcg ethinyl estradiol (EE) have a greater incidence of ovarian hormone production and follicular development, which can be managed by shortening the number of hormone-free days per COC cycle. This study evaluates differences in follicular development dur...


    pub_type: 杂志文章,随机对照试验


    authors: Rible RD,Taylor D,Wilson ML,Stanczyk FZ,Mishell DR Jr

    更新日期:2009-03-01 00:00:00

  • Emergency contraception in South Africa: knowledge, attitudes, and use among public sector primary healthcare clients.

    abstract::To determine knowledge of, attitudes toward, and use of emergency contraception (EC), interviews were held with 1068 clients of 89 public sector primary healthcare facilities in two urban and two rural areas of South Africa. Only 22.8% of the clients had heard of EC. Awareness was significantly lower in the most rural...


    pub_type: 杂志文章,多中心研究


    authors: Smit J,McFadyen L,Beksinska M,de Pinho H,Morroni C,Mqhayi M,Parekh A,Zuma K

    更新日期:2001-12-01 00:00:00

  • Endometrial safety of a novel monophasic combined oral contraceptive containing 0.02 mg ethinylestradiol and 2 mg chlormadinone acetate administered in a 24/4-day regimen over six cycles.

    abstract:BACKGROUND:This study was conducted to examine whether small doses of ethinylestradiol (EE, 0.02 mg) and chlormadinone acetate (CMA, 2 mg) administered in a novel 24/4-day regimen during six cycles would suffice to suppress proliferation and to cause secretory changes in the endometrium. STUDY DESIGN:This Phase II, ra...


    pub_type: 杂志文章,随机对照试验


    authors: Rabe T,Hartschuh E,Wahlstrom T,Höschen K,König S

    更新日期:2010-10-01 00:00:00

  • Termination of early pregnancy (menstrual induction) with 16-phenoxy-omega-tetranor PGE2 methylsulfonylamide.

    abstract::The efficacy and side effects of a new synthetic compound, 16-phenoxy-W-17, 18, 19, 20-tetranor prostaglandin E2 methylsulfonylamide, for menstrual induction. The study was conducted in an outpatient clinic in 240 patients with a delay in menstruation of 6-14 days. In 206 patients (86%) the immunologic pregnancy tes...


    pub_type: 杂志文章


    authors: Karim SM,Rao B,Ratnam SS,Prasad RN,Wong YM,Ilancheran A

    更新日期:1977-10-01 00:00:00

  • Use of intra- and extra-amniotic prostaglandins for the termination of pregnancies--report of multicentric trial in India.

    abstract::The Indian Council of Medical Research initiated a multicentric trial with prostaglandins in 1976 to assess the safety and efficacy of their use in midtrimester abortions. PGF2 alpha and 15-Me-PGF2 alpha were compared using the intra-amniotic (I.A.) route. 15-Me-PGF2 alpha was also evaluated by extra-amniotic (E.A.) r...


    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Tejuja S,Choudhury SD,Manchanda PK

    更新日期:1978-12-01 00:00:00

  • Continuation of long-acting reversible contraceptives among Medicaid patients.

    abstract:OBJECTIVE:Our objective was to compare continuation and complication rates of subdermal etonogestrel implants and intrauterine devices (IUDs) using Medicaid insurance claims. STUDY DESIGN:We performed a retrospective cohort study using insurance claims data for 15- to 44-year-old subjects receiving implants or IUDs fr...


    pub_type: 杂志文章


    authors: Romano MJ,Toye P,Patchen L

    更新日期:2018-04-24 00:00:00

  • Doing more for less: identifying opportunities to expand public sector access to safe abortion in South Africa through budget impact analysis.

    abstract:OBJECTIVE(S):To estimate the costs of public-sector abortion provision in South Africa and to explore the potential for expanding access at reduced cost by changing the mix of technologies used. STUDY DESIGN:We conducted a budget impact analysis using public sector abortion statistics and published cost data. We estim...


    pub_type: 杂志文章


    authors: Lince-Deroche N,Harries J,Constant D,Morroni C,Pleaner M,Fetters T,Grossman D,Blanchard K,Sinanovic E

    更新日期:2018-02-01 00:00:00

  • Effectiveness of the Yuzpe regimen of emergency contraception by cycle day of intercourse: implications for mechanism of action.

    abstract:OBJECTIVE:The purpose of this study was to provide evidence about the mechanism of action of the Yuzpe method of emergency contraception by examining effectiveness by cycle day of intercourse relative to ovulation. METHODS:Through a literature search, we identified eight studies that present the number of women treate...


    pub_type: 杂志文章


    authors: Trussell J,Ellertson C,Dorflinger L

    更新日期:2003-03-01 00:00:00

  • Uterine factors and risk of pregnancy in IUD users: a nested case-control study.

    abstract::Scarce data are available on the relation between the effectiveness of intrauterine device (IUD) and the gynecologic features of a woman. A nested case-control study was conducted to determine whether the uterine position and hysterometry affect the pregnancy rate of copper IUD. Seventy-one cases (pregnant women with ...


    pub_type: 杂志文章


    authors: Avecilla-Palau A,Moreno V

    更新日期:2003-03-01 00:00:00

  • Use of Norplant implants in a New York City clinic population.

    abstract::Two-hundred-eight women attending family planning clinics in New York City who received the Norplant contraceptive system during the first sixteen months of Norplant implants insertions were evaluated. Within this clinic population, Norplant implants were a popular contraceptive choice and were removed from 64 of the ...


    pub_type: 杂志文章


    authors: Gerber S,Westhoff C,Lopez M,Gordon L

    更新日期:1994-06-01 00:00:00

  • Not seeking yet trying long-acting reversible contraception: a 24-month randomized trial on continuation, unintended pregnancy and satisfaction.

    abstract:OBJECTIVES:To measure the 24-month impact on continuation, unintended pregnancy and satisfaction of trying long-acting reversible contraception (LARC) in a population seeking short-acting reversible contraception (SARC). STUDY DESIGN:We enrolled 916 women aged 18-29 who were seeking pills or injectables in a partially...


    pub_type: 杂志文章,随机对照试验


    authors: Hubacher D,Spector H,Monteith C,Chen PL

    更新日期:2018-06-01 00:00:00

  • Mifepristone-induced abortion and vaginal bleeding in subsequent pregnancy.

    abstract:BACKGROUND:The aim of this study is to explore the effect of first-trimester mifepristone-induced abortion on vaginal bleeding in subsequent pregnancy. STUDY DESIGN:This observational cohort study was conducted during 1998-2001 at antenatal clinics in Beijing, Chengdu, and Shanghai, China. The study enrolled 4,931 wom...


    pub_type: 杂志文章


    authors: Liang H,Gao ES,Chen AM,Luo L,Cheng YM,Yuan W

    更新日期:2011-12-01 00:00:00

  • Pharmacokinetic study of RU 486 and its metabolites after oral administration of single doses to pregnant and non-pregnant women.

    abstract::RU 486 and three of its metabolites (RU 42633-monodemethyl, RU 42848-didemethyl, and RU 42698-hydroxymetabolite) were determined by HPLC in plasma from nine non-pregnant and 36 pregnant women. Each non-pregnant subject took an oral dose of RU 486 (25, 100, 400 and 600 mg consecutively) once per menstrual cycle. Six of...


    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Shi YE,Ye ZH,He CH,Zhang GQ,Xu JQ,Van Look PF,Fotherby K

    更新日期:1993-08-01 00:00:00

  • Release of proteolytic enzymes from leucocytes attached to IUDs.

    abstract::The leucocytes adhering to intrauterine devices (IUDs) were predominantly mononuclear phagocytic cells (MPCs) and granulocytes. These cells released elastase and a plasminogen activator in the culture medium. The plasminogen activator was found to be immunologically identical to tissue activator, and the release patte...


    pub_type: 杂志文章


    authors: Casslén B,Ohlsson K,Lindholm K,Astedt B

    更新日期:1982-08-01 00:00:00

  • Levels of contraceptive seroids in breast milk and plasma of lactating women.

    abstract::Levels of contraceptive steroids in breast milk and plasma of lactating women were investigated. 7 lactating women received 150 mg medroxyprogesterone acetate (MPA) 1 week after delivery. 5 women (lactating) took 350 mcg norethisterone (NET) and 2 took 150 mcg d-norgestrel (d-ng) + 30 mcg ethinyl estradiol. Milk an...


    pub_type: 杂志文章


    authors: Saxena BN,Shrimanker K,Grudzinskas JG

    更新日期:1977-12-01 00:00:00

  • The effects of progesterone and progestins on endometrial proliferation.

    abstract::A total of 99 premenopausal and 27 postmenopausal women were evaluated to determine the quantity of glandular proliferation resulting from progestin inhibition of estrogen-primed subjects and of subjects without hormonal stimulation. Endometrial glandular proliferation rates were determined by using mitosis counts, pr...


    pub_type: 杂志文章


    authors: Moyer DL,Felix JC

    更新日期:1998-06-01 00:00:00

  • Complications of surgical termination of second-trimester pregnancy in obese versus nonobese women.

    abstract:BACKGROUND:Obesity is becoming increasingly common in obstetric and gynecologic populations, which may affect the safety of surgical termination of pregnancy. STUDY DESIGN:We performed a retrospective review of all patients undergoing second-trimester surgical termination of pregnancy by under ultrasound guidance term...


    pub_type: 杂志文章


    authors: Murphy LA,Thornburg LL,Glantz JC,Wasserman EC,Stanwood NL,Betstadt SJ

    更新日期:2012-10-01 00:00:00

  • Ultrastructural changes in the spermatozoa of langur monkeys Presbytis entellus entellus after vas occlusion with styrene maleic anhydride.

    abstract::Changes in the physical characteristics of semen and ultrastructure of the spermatozoa of langur monkeys after vas occlusion with styrene maleic anhydride (SMA), a polymer with pH-lowering action, are reported. Vas occlusion resulted in severe reversible hypospermia. Severe oligospermia was observed in the majority of...


    pub_type: 杂志文章


    authors: Lohiya NK,Manivannan B,Mishra PK

    更新日期:1998-02-01 00:00:00

  • A comparison of contraceptive procurement pre- and post-benefit change.

    abstract:BACKGROUND:In 2002, the Kaiser Foundation Health Plan in California changed its coverage policy to include 100% universal coverage for the most effective forms of contraception and for emergency contraceptive pills (ECPs). This study sought to evaluate whether removing the cost of contraception as a potential barrier t...


    pub_type: 杂志文章


    authors: Postlethwaite D,Trussell J,Zoolakis A,Shabear R,Petitti D

    更新日期:2007-11-01 00:00:00