当前位置： SCI文献检索 > DIGESTIVE DISEASES AND SCIENCES期刊下所有文献 > Microscopic colitis in children.

Microscopic colitis in children.

Abstract：

BACKGROUND:Microscopic colitis typically presents with chronic watery nonbloody diarrhea with normal endoscopy findings but abnormal inflammatory histopathological findings. As it is mainly a condition of the elderly, pediatric data is scarce. AIMS:To describe and characterize children with microscopic colitis. METHODS:The pathology database at the University of Alberta Hospital together with the pediatric inflammatory bowel disease database at the Stollery Children's Hospital were both searched from September 1996 to May 2008. Charts of all children under the age of 17 years who fulfilled the diagnostic criteria of microscopic colitis were examined. RESULTS:Eleven children (four girls, mean age at diagnosis 11.2 years, +/- 4.4 years) fulfilled the inclusion criteria. The patients were followed up for a mean of 24.8 months (standard deviation, SD 15.2 months). Two patients were on proton pump inhibitors, two had stool organisms, and two had immunodeficiency. All patients had normal endoscopy and colonoscopy on visualization. Five patients were diagnosed with lymphocytic colitis and the rest had nonspecific/eosinophilic microscopic colitis. The majority of children responded to mesalazine. One patient with immunodeficiency was difficult to manage. CONCLUSIONS:Microscopic colitis is rare in children. Microscopic eosinophilic colitis is an underdescribed variant of microscopic colitis. The majority of children with microscopic colitis respond well to aminosalicylic acid (5-ASA) medications. Microscopic colitis associated with immunodeficiency can be very challenging to manage. Large multicenter pediatric trials with long-term follow-up are needed to allow investigators to have a better understanding of this rare condition in children.

journal_name

Dig Dis Sci

journal_title

Digestive diseases and sciences

authors

El-Matary W,Girgis S,Huynh H,Turner J,Diederichs B

doi

10.1007/s10620-009-0964-4

subject

Has Abstract

pub_date

2010-07-01 00:00:00

pages

1996-2001

issue

7

eissn

0163-2116

issn

1573-2568

journal_volume

55

pub_type

杂志文章

相关文献

DIGESTIVE DISEASES AND SCIENCES文献大全
  • Can screening for IgG antibodies against Helicobacter pylori be used in clinical practice? Omit endoscopy in seropositive or seronegative patients?

    abstract：:The objective of this study was to test the feasibility of a screening strategy for IgG antibodies against Helicobacter pylori in patients presenting with upper abdominal complaints. Biopsy specimens were taken for histological and microbiological investigations from consecutive patients undergoing upper gastrointesti...

    journal_title：Digestive diseases and sciences

    pub_type： 杂志文章

    doi：10.1023/a:1026683026028

    authors： Werdmuller BF,V\/der Putten AB,Veenendaal RA,Lamers CB,Loffeld RJ

    更新日期：1998-10-01 00:00:00

  • A higher dose requirement of tacrolimus in active Crohn's disease may be related to a high intestinal P-glycoprotein content.

    abstract：:Tacrolimus, a relatively new therapeutic option for patients with corticosteroid-refractory Crohn's disease or ulcerative colitis, is a substrate for the apically directed efflux transporter P-glycoprotein (P-gp). Duodenal biopsy specimens obtained from a patient with corticosteroid-refractory Crohn's disease and with...

    journal_title：Digestive diseases and sciences

    pub_type： 杂志文章

    doi：10.1007/s10620-005-3053-3

    authors： Buchman AL,Paine MF,Wallin A,Ludington SS

    更新日期：2005-12-01 00:00:00

  • Feasibility of self-expandable metal stent placement with side-viewing endoscope for malignant distal duodenal obstruction.

    abstract：BACKGROUND AND AIM:Self-expandable metal stents (SEMSs) have been a good treatment option for malignant intestinal obstruction. However, stent placement with a gastroscope can be technically difficult for the distal duodenum obstruction. A side-viewing duodenoscope may be helpful for these patients. We report our exper...

    journal_title：Digestive diseases and sciences

    pub_type： 杂志文章

    doi：10.1007/s10620-014-3343-8

    authors： Park JM,Min BH,Lee SH,Chung KH,Lee JM,Song BJ,Lee JK,Ryu JK,Kim YT

    更新日期：2015-02-01 00:00:00

  • Artificial liver. State of the art.

    abstract：:If an effective hepatic assist system existed, it could serve as a bridge to transplantation. Most of the patients waiting for liver transplantation have chronic liver insufficiency but are not in hepatic coma. Various hepatic assist systems have been used to salvage patients with acute liver insufficiency. Most attem...

    journal_title：Digestive diseases and sciences

    pub_type： 历史文章,杂志文章,评审

    doi：10.1007/BF01307531

    authors： Takahashi T,Malchesky PS,Nosé Y

    更新日期：1991-09-01 00:00:00

  • False negative fecal occult blood test may be associated with increased mortality from colorectal cancer.

    abstract：BACKGROUND:Fecal Occult Blood Test (FOBT) is an accepted screening test for colorectal cancer (CRC). It has been shown to decrease mortality by up to 30%. The outcome of screening failures has not been adequately studied. AIMS:The purpose of this study was to assess the outcome of patients who were diagnosed with CRC ...

    journal_title：Digestive diseases and sciences

    pub_type： 杂志文章

    doi：10.1007/s10620-013-2702-1

    authors： Half EE,Mlynarsky L,Naftali T,Benjaminov F,Konikoff FM

    更新日期：2013-09-01 00:00:00

  • Impact of Angiotensin II Signaling Blockade on Clinical Outcomes in Patients with Inflammatory Bowel Disease.

    abstract：BACKGROUND:Preclinical data demonstrate that activation of the renin-angiotensin system (RAS) contributes to mucosal inflammation, and RAS inhibition by angiotensin-converting-enzyme inhibitors (ACEI) and angiotensin receptor blockers (ARB) improves colitis in animal models. Less is known regarding the effects of RAS i...

    journal_title：Digestive diseases and sciences

    pub_type： 杂志文章

    doi：10.1007/s10620-019-5474-4

    authors： Jacobs JD,Wagner T,Gulotta G,Liao C,Li YC,Bissonnette M,Pekow J

    更新日期：2019-07-01 00:00:00

  • Hepatopulmonary syndrome in noncirrhotic portal hypertensive patients.

    abstract：:Hepatopulmonary syndrome has yet not been sufficiently assessed in noncirrhotic portal hypertension. The prevalence of hepatopulmonary syndrome was determined in 31 consecutive patients with noncirrhotic portal hypertension (19 idiopathic portal hypertension, 7 portal vein thrombosis, 5 congenital hepatic fibrosis) an...

    journal_title：Digestive diseases and sciences

    pub_type： 杂志文章

    doi：10.1023/a:1022549018807

    authors： Kaymakoglu S,Kahraman T,Kudat H,Demir K,Cakaloglu Y,Adalet I,Dincer D,Besisik F,Boztas G,Sözen AB,Mungan Z,Okten A

    更新日期：2003-03-01 00:00:00

  • Disseminated aseptic abscesses associated with Crohn's disease: a new entity?

    abstract：:Our purpose is to describe seven cases of disseminated aseptic abscesses with regard to clinical, biological, radiological, and histological information, treatment, and outcome. Data were collected on seven Caucasian patients who had proven sterile deep abscesses diagnosed in French university hospitals. The onset of ...

    journal_title：Digestive diseases and sciences

    pub_type： 杂志文章

    doi：10.1023/a:1018835228850

    authors： André M,Aumaître O,Papo T,Kemeny JL,Vital-Durand D,Rousset H,Ninet J,Pointud P,Charlotte F,Godeau B,Schmidt J,Marcheix JC,Piette JC

    更新日期：1998-02-01 00:00:00

  • Nerve-mediated nitric oxide production by opossum lower esophageal sphincter.

    abstract：:Antagonists of nitric oxide synthesis inhibit nerve-induced hyperpolarization and relaxation of muscle from the opossum lower esophageal sphincter. These studies test the hypothesis that nitric oxide is released during stimulation of intrinsic esophageal nerves. The intrinsic nerves were stimulated with an electrical ...

    journal_title：Digestive diseases and sciences

    pub_type： 杂志文章

    doi：10.1007/BF02088117

    authors： Murray J,Bates JN,Conklin JL

    更新日期：1994-09-01 00:00:00

  • Different roles of tumor marker monitoring after curative resections of gastric and colorectal cancers.

    abstract：:We previously demonstrated that false-positive findings for tumor markers are frequently observed, and that the sensitivity of marker monitoring for early detection of the recurrence is low after curative resection of gastric cancer. The aim of this study was to investigate whether such characters are specific to gast...

    journal_title：Digestive diseases and sciences

    pub_type： 杂志文章

    doi：10.1007/s10620-007-0046-4

    authors： Ohtsuka T,Nakafusa Y,Sato S,Kitajima Y,Tanaka M,Miyazaki K

    更新日期：2008-06-01 00:00:00

  • Correction to: Characterization of Creatine Kinase Levels in Tofacitinib‑Treated Patients with Ulcerative Colitis: Results from Clinical Trials.

    abstract：:The article "Characterization of Creatine Kinase Levels in Tofacitinib-Treated Patients with Ulcerative Colitis: Results from Clinical Trials", written by Remo Panaccione, John D. Isaacs, Lea Ann Chen, Wenjin Wang, Amy Marren, Kenneth Kwok, Lisy Wang, Gary Chan and Chinyu Su, was originally published electronically on...

    journal_title：Digestive diseases and sciences

    pub_type： 已发布勘误

    doi：10.1007/s10620-020-06638-z

    authors： Panaccione R,Isaacs JD,Chen LA,Wang W,Marren A,Kwok K,Wang L,Chan G,Su C

    更新日期：2020-10-10 00:00:00

  • Magnesium transport across colon ascendens of the rat.

    abstract：:Concentration and voltage dependence of unidirectional Mg fluxes across the rat colon ascendens were measured in a modified Ussing chamber. Mucosa (M) to serosa (S) Mg flux exhibits a cellular component, whereas SM flux is totally diffusive. At all the concentrations between 0.125 and 8 mmol/liter MS Mg transport is h...

    journal_title：Digestive diseases and sciences

    pub_type： 杂志文章

    doi：10.1007/BF01536699

    authors： Karbach U

    更新日期：1989-12-01 00:00:00

  • Effectiveness of concomitant enteral nutrition therapy and infliximab for maintenance treatment of Crohn's disease in adults.

    abstract：BACKGROUND:One of the problems associated with infliximab (IFX) treatment for Crohn's disease (CD) is loss of response during maintenance therapy. AIMS:The aim of this multicenter, retrospective, cohort study was to determine whether enteral nutrition (EN) added to the IFX therapy regimen is effective for maintaining ...

    journal_title：Digestive diseases and sciences

    pub_type： 杂志文章

    doi：10.1007/s10620-012-2374-2

    authors： Hirai F,Ishihara H,Yada S,Esaki M,Ohwan T,Nozaki R,Ashizuka S,Inatsu H,Ohi H,Aoyagi K,Mizuta Y,Matsumoto T,Matsui T

    更新日期：2013-05-01 00:00:00

  • Selection of HCV NS5A quasispecies during IFN therapy in patients with chronic HCV.

    abstract：:Interferon treatment of chronic hepatitis C virus infection is successful in a minority of patients. The sequence of the interferon sensitivity determining region (ISDR) of the NS5A protein may determine the outcome of therapy in patients infected with HCV genotype 1. To determine whether IFN treatment caused selectio...

    journal_title：Digestive diseases and sciences

    pub_type： 杂志文章

    doi：10.1023/a:1010623417345

    authors： Paterson M,Laxton C,Goldin RD,Ackrill AM,Foster GR

    更新日期：2001-07-01 00:00:00

  • [*C]octanoic acid breath test to measure gastric emptying rate of solids.

    abstract：:We have developed a breath test to measure solid gastric emptying using a standardized scrambled egg test meal (250 kcal) labeled with [14C]octanoic acid or [13C]octanoic acid. In vitro incubation studies showed that octanoic acid is a reliable marker of the solid phase. The breath test was validated in 36 subjects by...

    journal_title：Digestive diseases and sciences

    pub_type： 杂志文章

    doi：10.1007/BF02300385

    authors： Maes BD,Ghoos YF,Rutgeerts PJ,Hiele MI,Geypens B,Vantrappen G

    更新日期：1994-12-01 00:00:00

  • Metallic or plastic stent for bile duct obstruction in ampullary cancer?

    abstract：BACKGROUND AND AIMS:Although ampullary cancer is a relatively uncommon malignancy, it is frequently associated with biliary obstruction. Endoscopic biliary drainage is regarded as a palliative treatment of choice for patients with inoperable ampullary cancer. However, there are no data concerning choice of stent in thi...

    journal_title：Digestive diseases and sciences

    pub_type： 临床试验,杂志文章

    doi：10.1007/s10620-011-1909-2

    authors： Park SB,Kim HW,Kang DH,Choi CW,Ryu JH,Chu CW,Lee SY,Jeong YI,Yeo HJ,Kim EJ

    更新日期：2012-03-01 00:00:00

  • Plasma levels of matrix metalloproteinase-2 (MMP-2) and tissue inhibitors of metalloproteinases -1 and -2 (TIMP-1 and TIMP-2) as noninvasive markers of liver disease in chronic hepatitis C: comparison using ROC analysis.

    abstract：:As chronic liver disease progresses, an imbalance occurs between synthesis and breakdown of extracellular matrix (ECM). Matrix metalloproteinases (MMPs) are involved in degrading ECM while tissue inhibitors of metalloproteinases (TIMPs) prevent their fibrolytic action. We determined if plasma levels of MMP-2, TIMP-1 a...

    journal_title：Digestive diseases and sciences

    pub_type： 杂志文章

    doi：10.1023/a:1026630129025

    authors： Walsh KM,Timms P,Campbell S,MacSween RN,Morris AJ

    更新日期：1999-03-01 00:00:00

  • Anomalous plasma cyclic AMP responses to glucagon in patients with liver disease.

    abstract：:The purpose of the present study is to show anomalies of the plasma cAMP response of patients with hepatic disorders to a single injection of a low dose of glucagon (1 microgram/kg body wt). The response was markedly blunted in patients with liver cirrhosis and potentiated in patients with acute or chronic hepatitis. ...

    journal_title：Digestive diseases and sciences

    pub_type： 杂志文章

    doi：10.1007/BF01308330

    authors： Maekubo H,Matsushima T,Okada F,Honma M,Ui M

    更新日期：1980-09-01 00:00:00

  • Clinical impact of HAb18G/CD147 expression in esophageal squamous cell carcinoma.

    abstract：BACKGROUND:HAb18G/CD147 expression has been associated with many tumor invasion molecules, which play important roles in recurrence and poor differentiation of esophageal squamous cell carcinoma (ESCC). However, the clinical implications of HAb18G/CD147 in ESCC are still unclear. AIMS:In this study, we clarified the c...

    journal_title：Digestive diseases and sciences

    pub_type： 杂志文章

    doi：10.1007/s10620-011-1812-x

    authors： Zhu S,Li Y,Mi L,Zhang Y,Zhang L,Gong L,Han X,Yao L,Lan M,Chen Z,Zhang W

    更新日期：2011-12-01 00:00:00

  • Extending gastric emptying scintigraphy from two to four hours detects more patients with gastroparesis.

    abstract：:Gastric emptying scintigraphy (GES) is usually performed for up to 2 hr to measure the gastric emptying (GE) of solids. Symptomatic patients, however, may have borderline results at 2 hr, making it difficult to determine whether a gastric motor disorder is present. The aim of this study was to assess whether extending...

    journal_title：Digestive diseases and sciences

    pub_type： 杂志文章

    doi：10.1023/a:1005697422454

    authors： Guo JP,Maurer AH,Fisher RS,Parkman HP

    更新日期：2001-01-01 00:00:00

  • Altered liver morphology after portal vein thrombosis: not always cirrhosis.

    abstract：:The macroscopic appearance of the liver after primary portal vein thrombosis often mimics cirrhosis, despite the absence of bridging fibrosis at histology. The purpose of this study was to describe unique morphologic changes of the liver after portal venous thrombosis. A retrospective review was performed to find pati...

    journal_title：Digestive diseases and sciences

    pub_type： 杂志文章

    doi：10.1007/s10620-008-0201-6

    authors： Tublin ME,Towbin AJ,Federle MP,Nalesnik MA

    更新日期：2008-10-01 00:00:00

  • Prognostic Factors for Acute Transjugular Intrahepatic Portosystemic Shunt Occlusion Using Expanded Polytetrafluoroethylene-Covered Stent.

    abstract：BACKGROUND:The expanded polytetrafluoroethylene (ePTFE)-covered stent has been widely used in the transjugular intrahepatic portosystemic shunt (TIPS) procedure. However, the epidemiologic data of acute TIPS occlusion (ATO) and the underlying mechanisms are scarce. AIMS:The purpose of this study was to evaluate the in...

    journal_title：Digestive diseases and sciences

    pub_type： 杂志文章

    doi：10.1007/s10620-019-06008-4

    authors： Wang X,Luo X,Zhao M,Song J,Li X,Yang L

    更新日期：2020-10-01 00:00:00

  • Association between 6-n-propylthiouracil (PROP) bitterness and colonic neoplasms.

    abstract：:Inadequate vegetable intake appears to increase colon cancer risk. Since genetic variation in taste influences vegetable preference, we tested associations between bitterness of 6-n-propylthiouracil (PROP), a measure of taste genetics, and number of colonic polyps, a measure of colon cancer risk, in 251 men who underw...

    journal_title：Digestive diseases and sciences

    pub_type： 杂志文章

    doi：10.1007/s10620-005-2462-7

    authors： Basson MD,Bartoshuk LM,Dichello SZ,Panzini L,Weiffenbach JM,Duffy VB

    更新日期：2005-03-01 00:00:00

  • Effect of bowel preparation with polyethylene glycol on quality of capsule endoscopy.

    abstract：BACKGROUND AND AIMS:Capsule endoscopy (CE) has the problem that lumen visualization is impaired by bubbles, bile, and debris. The benefits of bowel preparation are still controversial and the best method remains to be determined. The objective of this study was to evaluate the effect of the method of bowel preparation ...

    journal_title：Digestive diseases and sciences

    pub_type： 杂志文章,随机对照试验

    doi：10.1007/s10620-010-1500-2

    authors： Park SC,Keum B,Seo YS,Kim YS,Jeen YT,Chun HJ,Um SH,Kim CD,Ryu HS

    更新日期：2011-06-01 00:00:00

  • Fructose-Bisphosphate Aldolase A Regulates Hypoxic Adaptation in Hepatocellular Carcinoma and Involved with Tumor Malignancy.

    abstract：BACKGROUND:Hypoxia is an important factor in malignant tumors, and glycolysis is a major metabolic contributor in their development. Glycolytic enzymes have gained increasing attention as potential therapeutic targets because they are associated with cancer-specific metabolism. Fructose-bisphosphate aldolase A (ALDOA),...

    journal_title：Digestive diseases and sciences

    pub_type： 杂志文章

    doi：10.1007/s10620-019-05642-2

    authors： Li X,Jiang F,Ge Z,Chen B,Yu J,Xin M,Wang J,An L,Wei J,Wu L

    更新日期：2019-11-01 00:00:00

  • Effect of altering gastric emptying on postprandial plasma glucose concentrations following a physiologic meal in type-II diabetic patients.

    abstract：:The purpose of this study was to determine the effects of altering gastric emptying on postprandial plasma glucose concentration after a physiologic meal in patients with type II diabetes mellitus (T II DM). Nine T II DM patients underwent a double-blind, randomized, three-way crossover study, receiving erythromycin 2...

    journal_title：Digestive diseases and sciences

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1023/a:1022528414264

    authors： Gonlachanvit S,Hsu CW,Boden GH,Knight LC,Maurer AH,Fisher RS,Parkman HP

    更新日期：2003-03-01 00:00:00

  • The clinical significance and natural history of the double pylorus.

    abstract：:The double pylorus is a fistulous communication between the gastric antrum and duodenal bulb. In most instances, it is believed to be a complication of peptic ulcer disease. In prior reports, the longest follow-up has been only 5 years. We report four cases of double pylorus, three of which have been followed medicall...

    journal_title：Digestive diseases and sciences

    pub_type： 杂志文章

    doi：10.1007/BF01296254

    authors： Einhorn RI,Grace ND,Banks PA

    更新日期：1984-03-01 00:00:00

  • Protein kinase C activity as a potential marker for colorectal neoplasia.

    abstract：:Protein kinase C (PKC) is a mediator of transmembrane signal transduction, important in cell growth and differentiation. Cell activation by extracellular signals is associated with a translocation of PKC from the cytosol to the membrane. We measured and compared PKC activity in cytosol and membrane fractions of normal...

    journal_title：Digestive diseases and sciences

    pub_type： 杂志文章

    doi：10.1007/BF02088328

    authors： McGarrity TJ,Peiffer LP

    更新日期：1994-03-01 00:00:00

  • Nonalcoholic Fatty Liver Disease Demonstrates a Pre-fibrotic and Premalignant Molecular Signature.

    abstract：BACKGROUND:Metabolic syndrome contributing to nonalcoholic fatty liver disease (NAFLD) can lead to hepatic dysfunction, steatohepatitis, cirrhosis, and hepatocellular carcinoma. AIMS:In this study, we tested whether diet-induced fatty liver in a mouse model physiologically mimicked human NAFLD, and whether transcripti...

    journal_title：Digestive diseases and sciences

    pub_type： 杂志文章

    doi：10.1007/s10620-018-5398-4

    authors： Almanza D,Gharaee-Kermani M,Zhilin-Roth A,Rodriguez-Nieves JA,Colaneri C,Riley T,Macoska JA

    更新日期：2019-05-01 00:00:00

  • Influence of orlistat on the regulation of gallbladder contraction in man: a randomized double-blind placebo-controlled crossover study.

    abstract：:Orlistat (tetrahydrolipstatin) is a potent inhibitor of gastric and pancreatic lipase activity causing a diminution of free fatty acids in the intestinal lumen. The release of cholecystokinin (CCK) critically depends on the presence of free fatty acids in the small intestine. Postprandial CCK release and gallbladder c...

    journal_title：Digestive diseases and sciences

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1007/BF02100135

    authors： Froehlich F,Hartmann D,Guezelhan C,Gonvers JJ,Jansen JB,Fried M

    更新日期：1996-12-01 00:00:00