Selection of HCV NS5A quasispecies during IFN therapy in patients with chronic HCV.

abstract：:Sulfated and unsulfated bile acid composition was studied in serum and bile in 10 patients with alcoholic cirrhosis. Samples, collected before and 2 months after portacaval anastomosis, were analyzed using a gaschromatographic method. Mean total serum bile acid levels rose from 32.0 +/- 5.3 (SE) mumol/liter before to ...

journal_title：Digestive diseases and sciences

authors： Capocaccia L,Attili AF,Cantafora A,Bracci F,Paciscopi L,Puoti C,Pièche U,Angelico M

更新日期：1981-06-01 00:00:00

abstract：:The effects of 10-day bilateral adrenalectomy on morphometry, proliferation, and apoptosis were determined in the small intestine of 3-month-old Sprague-Dawley rats. The activities of sucrase, lactase, and its respective mRNA, aminopeptidase N, and intestinal alkaline phosphatase were also evaluated. Adrenalectomy lea...

journal_title：Digestive diseases and sciences

authors： Foligne B,Aissaoui S,Senegas-Balas F,Cayuela C,Bernard P,Antoine JM,Balas D

更新日期：2001-06-01 00:00:00

abstract：:A classification of gastrointestinal motility disorders is offered based upon the type of disorder in transit (delay or acceleration), and the region of the gastrointestinal tract affected. Specific abnormalities of myoelectrical patterns are identified when possible and related to disturbances in transit in the stoma...

journal_title：Digestive diseases and sciences

authors： Vantrappen G,Janssens J,Coremans G,Jian R

更新日期：1986-09-01 00:00:00

abstract：BACKGROUND AND AIMS:The Chronic Hepatitis Cohort Study (CHeCS) is a longitudinal observational study of risks and benefits of treatments and care in patients with chronic hepatitis B (HBV) and C (HCV) infection from four US health systems. We hypothesized that comparative effectiveness methods-including a centralized d...

journal_title：Digestive diseases and sciences

authors： Lu M,Rupp LB,Moorman AC,Li J,Zhang T,Lamerato LE,Holmberg SD,Spradling PR,Teshale EH,Vijayadeva V,Boscarino JA,Schmidt MA,Nerenz DR,Gordon SC

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND AND AIMS:The present study aimed to identify the differential expressed genes that are related to acute pancreatitis. METHODS:Microarray datasets GSE109227 and GSE3644 were downloaded from the public database and analyzed to screen the genes. Afterward, integrated analysis of these genes were performed, inc...

journal_title：Digestive diseases and sciences

authors： Fan L,Hui X,Mao Y,Zhou J

更新日期：2020-06-01 00:00:00

abstract：:The evaluation of a group of polyamine analogs as agents to ameliorate diarrhea-predominant irritable bowel syndrome is described. Each compound was assessed when administered subcutaneously in a psychological stress-induced model of irritable bowel syndrome in rodents for its ability to reduce stool output in a dose-...

journal_title：Digestive diseases and sciences

authors： Bergeron RJ,Wiegand J,Fannin TL

更新日期：2001-12-01 00:00:00

abstract：AIMS:The purpose of this retrospective study was to assess clinical outcomes of endoscopic bougie dilation of esophageal strictures after radiation therapy for head and neck cancer, and to assess the risk factors which affect the treatment success. METHODS:Thirty-one patients with esophageal stricture due to radiation...

journal_title：Digestive diseases and sciences

authors： Tuna Y,Koçak E,Dinçer D,Köklü S

更新日期：2012-02-01 00:00:00

abstract：:In this study, we examined the effect of rebamipide, a mucoprotective drug, on gastric ulcer healing in Mongolian gerbils infected with H. pylori. Male Mongolian gerbils were inoculated with H. pylori or vehicle alone 12 hr after the production of an acetic acid-induced gastric ulcer. On day 5, the gerbils inoculated ...

journal_title：Digestive diseases and sciences

authors： Watanabe T,Higuchi K,Hamaguchi M,Tanigawa T,Wada R,Tominaga K,Fujiwara Y,Arakawa T

更新日期：2002-07-01 00:00:00

abstract：BACKGROUND:Corticotropin-releasing factor (CRF) peptides exert profound effects on the secretomotor function of the gastrointestinal tract. Nevertheless, despite the presence of CRF peptides and receptors in colonic tissue, their influence on colonic blood flow (CBF) is unknown. AIM:To determine the effect and mechani...

journal_title：Digestive diseases and sciences

authors： Akiba Y,Kaunitz JD,Million M

更新日期：2015-04-01 00:00:00

abstract：:One hundred nineteen children, either French or from the Ivory Coast, aged 1-8 years, were submitted to pancreatic function testing by duodenal aspiration. Trypsin, chymotrypsin, lipase, phospholipase, amylase, volume, bicarbonate, chloride, and calcium were estimated before and after an intravenous injection of 1 CU ...

journal_title：Digestive diseases and sciences

authors： Sauniere JF,Sarles H,Attia Y,Lombardo A,Yoman TN,Laugier R,Manlan K,Sahel J

更新日期：1986-05-01 00:00:00

abstract：:Chronic pancreatitis associated with inflammatory bowel disease is now considered as extraintestinal manifestation of that disease. The clinical and radiological features of the new entity are markedly different from those of chronic calcifying pancreatitis. We report the case of a 68-year-old man presenting with a ps...

journal_title：Digestive diseases and sciences

authors： Grandval P,Barthet M,Desjeux A,Garcia S,Boustiere C,Poilroux B,Grimaud JC

更新日期：2001-04-01 00:00:00

abstract：:The use of total parenteral nutrition and enteral nutrition in inflammatory bowel disease has become commonplace. Except for well-documented improvements in nutritional parameters, the efficacy of these treatments for primary therapy or for complications remains largely unproven. ...

journal_title：Digestive diseases and sciences

authors： Whittaker JS

更新日期：1987-12-01 00:00:00

abstract：:Fibrin ring granuloma is characterized by a fibrinous ring surrounding a central fat vacuole. It has been found in the liver and bone marrow of patients with Q fever, and occasionally with visceral leishmaniasis, cytomegalovirus, Epstein-Barr virus, Staphylococcus epidermidis infections, Hodgkin's lymphoma, and hypers...

journal_title：Digestive diseases and sciences

authors： Ruel M,Sevestre H,Henry-Biabaud E,Courouce AM,Capron JP,Erlinger S

更新日期：1992-12-01 00:00:00

abstract：:The characteristic features of a 48-year-old male presenting with isolated acromegaly caused by a GRH-producing pancreatic endocrine tumor bearing no relation to MEN1 was reported. The clinical features, laboratory findings, and sellar enlargement were improved after removal of the pancreatic tumor. The resected pancr...

journal_title：Digestive diseases and sciences

authors： Kawa S,Ueno T,Iijima A,Midorikawa T,Fujimori Y,Tokoo M,Oguchi H,Kiyosawa K,Imai Y,Kaneko G,Kuroda T,Hashizume K,Osamura RY,Katakami H

更新日期：1997-07-01 00:00:00

abstract：:Little information on functional status and well-being is available in patients with functional gastrointestinal disease. We aimed to evaluate whether quality of life is poorer in patients with functional dyspepsia. A consecutive sample of 73 patients with functional dyspepsia completed a validated questionnaire prior...

journal_title：Digestive diseases and sciences

authors： Talley NJ,Weaver AL,Zinsmeister AR

更新日期：1995-03-01 00:00:00

abstract：BACKGROUND:Accumulating evidence suggests that Foxp3+ regulatory T (Treg) cells act as inhibitory mediators of inflammation; however, the in vivo mechanism underlying this protection remains elusive in liver diseases. AIMS:To clarify the in vivo role of Foxp3+ Treg cells in liver fibrosis, we used the DEREG mouse, whi...

journal_title：Digestive diseases and sciences

authors： Roh YS,Park S,Lim CW,Kim B

更新日期：2015-07-01 00:00:00

abstract：:Hepatitis C virus (HCV) infection has an estimated prevalence of 3% around the world. Unfortunately, many persons with HCV infection are asymptomatic. The aim of this study was to determine the prevalence of hepatitis C Virus infection in asymptomatic persons. This study was carried out in a population-based cross-sec...

journal_title：Digestive diseases and sciences

authors： Méndez-Sánchez N,Ponciano-Rodriguez G,Chávez-Tapia NC,Motola-Kuba D,Almeda-Valdes P,Sánchez-Lara K,Ramos MH,Uribe M

更新日期：2005-04-01 00:00:00

abstract：BACKGROUND:Peyer's patches (PPs), which are covered by specialized follicle-associated epithelium (FAE) including M cells, play a central role in immune induction in the gastrointestinal tract. This study is to investigate a new molecule to characterize PPs. METHODS:We generated a monoclonal antibody (mAb 10-15-3-3) t...

journal_title：Digestive diseases and sciences

authors： Tokuhara D,Nochi T,Matsumura A,Mejima M,Takahashi Y,Kurokawa S,Kiyono H,Yuki Y

更新日期：2014-11-01 00:00:00

abstract：:We compared the stress-strain distributions obtained from isolated segments of the guinea pig duodenum, jejunum, and distal ileum, and the relation between the elastic properties and the collagen content. The segments were immersed in Krebs-Ringer solution containing 10(-2) M MgCl2 to abolish contractile activity. Ste...

journal_title：Digestive diseases and sciences

authors： Storkholm JH,Villadsen GE,Jensen SL,Gregersen H

更新日期：1998-09-01 00:00:00

abstract：:Survivin is known to be overexpressed in various human malignancies, including pancreatic cancer, and to cause resistance to radiation and chemotherapy, so the regulation of this molecule could be a new strategy for treating pancreatic cancer. In our study, a short interfering RNA (siRNA) plasmid expression vector aga...

journal_title：Digestive diseases and sciences

authors： Liu WS,Yan HJ,Qin RY,Tian R,Wang M,Jiang JX,Shen M,Shi CJ

更新日期：2009-01-01 00:00:00

abstract：:Of 112 patients with peptic ulcer disease examined for oral carriage of Candida, 66 (59%) were carriers. Candida carriage was associated with blood group O (P < 0.05) and, independently, with nonsecretion of blood group antigens (P < 0.01). For each subject, the presence or absence of yeasts was found to be a constant...

journal_title：Digestive diseases and sciences

authors： Burford-Mason AP,Willoughby JM,Weber JC

更新日期：1993-08-01 00:00:00

abstract：:The neutralizing capacity of two antacids (Alucol = A, Syntrogel = S), differing both in their composition and theoretical neutralizing capacity, was evaluated in vitro and in vivo. In vitro at pH 3.5, 1 ml of A or S neutralizes 3.9 and 1.6 meq of acid, respectively, in an aqueous solution. When tested in vivo in the ...

journal_title：Digestive diseases and sciences

authors： Berchtold P,Reinhart WH,Niederhäuser U,Koller U,Halter F

更新日期：1985-06-01 00:00:00

abstract：UNLABELLED:The lactulose breath test (LBT) and gastroenterocolonic scintigraphy (GECS) can both be used to measure orocecal transit time (OCTT). The aims of this study were (1) to measure OCTT by LBT and GECS and (2) to determine whether lactulose alters orocecal transit. METHODS:Eight normal subjects underwent simult...

journal_title：Digestive diseases and sciences

authors： Miller MA,Parkman HP,Urbain JL,Brown KL,Donahue DJ,Knight LC,Maurer AH,Fisher RS

更新日期：1997-01-01 00:00:00

abstract：:The gold standard for measuring gastric emptying is scintigraphy, either with digestible solids or liquids. Unfortunately, this method is expensive and of limited availability. An alternative could be to use radiopaque markers (ROMs). Our aim was to compare these two tests in healthy volunteers and in patients to see ...

journal_title：Digestive diseases and sciences

authors： Stotzer PO,Fjälling M,Grétarsdóttir J,Abrahamsson H

更新日期：1999-04-01 00:00:00

abstract：INTRODUCTION:The impact of antithrombotic treatment on the findings of small-bowel capsule endoscopy for patients with obscure gastrointestinal bleeding remains contentious. We aimed to determine the effect of these agents on small-bowel video capsule endoscopy positive findings. METHODS:MEDLINE, Cochrane Library, and...

journal_title：Digestive diseases and sciences

authors： Tziatzios G,Gkolfakis P,Papanikolaou IS,Triantafyllou K

更新日期：2019-01-01 00:00:00

abstract：AIM:Intestinal ischemia reperfusion (IR) causes tissue injury in two ways, starting a pro-inflammatory cascade and oxidative stress. The aim of this study was to investigate the possible protective effects of caffeic acid phenethyl ester (CAPE), which has antioxidant and anti-inflammatory properties, against intestinal...

journal_title：Digestive diseases and sciences

authors： Yildiz Y,Serter M,Ek RO,Ergin K,Cecen S,Demir EM,Yenisey C

更新日期：2009-04-01 00:00:00

abstract：:In addition to cholecystokinin, other hormones have been suggested to be involved in regulation of postprandial gallbladder contraction. We aimed to evaluate effects of growth hormone (GH) on gallbladder contractility and cholecystokinin release. Gallbladder and gastric emptying (by ultrasound) and cholecystokinin rel...

journal_title：Digestive diseases and sciences

authors： Moschetta A,Twickler TB,Rehfeld JF,van Ooteghem NA,Cabezas MC,Portincasa P,van Berge-Henegouwen GP,van Erpecum KJ

更新日期：2004-03-01 00:00:00

abstract：BACKGROUND:Although the use of cold snare polypectomy (CSP) has spread rapidly, its safety for pedunculated (Ip) polyps remains controversial. In particular, the outcomes of hot snare polypectomy (HSP) and CSP for Ip polyps have not been previously compared. AIMS:This study evaluated whether the rate of delayed postpo...

journal_title：Digestive diseases and sciences

authors： Arimoto J,Chiba H,Ashikari K,Fukui R,Tachikawa J,Okada N,Suto T,Kawano N,Niikura T,Kuwabara H,Nakaoka M,Ida T,Goto T,Nakajima A

更新日期：2020-07-04 00:00:00

abstract：BACKGROUND:Nonalcoholic fatty liver disease (NAFLD) is now recognized as a leading cause of liver dysfunction. Gastroesophageal reflux disease (GERD) is a common disorder causing symptoms that often impair patients' quality of life. In recent years, the prevalence of both these diseases has increased, partially overlap...

journal_title：Digestive diseases and sciences

authors： Catanzaro R,Calabrese F,Occhipinti S,Anzalone MG,Italia A,Milazzo M,Marotta F

更新日期：2014-08-01 00:00:00

abstract：BACKGROUND:There have been conflicting reports comparing the prevalence of large polyps (>9 mm) between Hispanics and non-Hispanic whites (NHW). Differences between Hispanic subpopulations may account for these variations. AIMS:We aimed to assess the prevalence of large polyps (>9 mm) in Hispanics from Mexican- and no...

journal_title：Digestive diseases and sciences

authors： Avalos DJ,Zuckerman MJ,Dwivedi A,Dodoo C,Satiya J,Castro FJ

更新日期：2019-01-01 00:00:00