Abstract：
BACKGROUND:Laparoscopic resection for the cure of rectal cancer is still a matter of debate. Laparoscopic approach is more complex and with a long learning curve, which may results in an increase in morbidity and mortality. This study aimed to retrospectively analyze the impact of laparoscopic resection for rectal cancer on operative outcome of a hospital in a developing country. METHODS:All patients presenting with rectal cancer surgically managed by laparoscopic approach were enrolled. Exclusion criteria were total coloproctectomy, palliative procedures, and metastatic disease. The following parameters were accessed: general characteristics, technical details, mortality, and the outcome. RESULTS:From January 2000 to January 2008, 60 patients with histologically proven rectal cancer were enrolled, and 43 were excluded. Mean age, 58.5 +/- 15.9 years. A 76.6% of patients had cancer-advanced stages. There were 20 anterior resections, 31 abdomino-perineal resections, and nine pull-through procedures. Conversion rate was 3.3%, and there had 3.3% of operative complications. No procedure-related death. With the mean follow-up of 33 months, 77.8% patients are alive and disease-free, 5.6% are alive with disease: distant metastasis in 2.8%, and local recurrence in 2.8%. About 16.7% have died from cancer-related causes. No port site or wound metastasis have occurred. CONCLUSIONS:This study showed the favorable short-term operative results in patients who underwent laparoscopic resection for rectal cancer. The low conversion rate of 3.3%, 3.3% complication rate, and 0% of a 30-day mortality attributed to confirm the feasibility of laparoscopic approach in the surgical treatment of rectal cancer.
journal_name
Int J Colorectal Disjournal_title
International journal of colorectal diseaseauthors
Hiep PN,Vu PA,Thien HHdoi
10.1007/s00384-009-0789-9subject
Has Abstractpub_date
2009-12-01 00:00:00pages
1465-9issue
12eissn
0179-1958issn
1432-1262journal_volume
24pub_type
杂志文章abstract：BACKGROUND AND AIMS:The prognostic value of the degree of apoptosis in colorectal cancer is controversial. This study evaluates the putative clinical usefulness of measuring caspase-3 activity as a prognostic factor in colonic cancer patients receiving 5-fluoracil adjuvant chemotherapy. MATERIALS AND METHODS:We evalua...
journal_title：International journal of colorectal disease
pub_type： 杂志文章
doi：10.1007/s00384-007-0362-3
更新日期：2008-01-01 00:00:00
abstract：BACKGROUND AND AIMS:The perioperative use of a single course adjuvant portal vein infusion chemotherapy in patients with potentially curable colorectal cancer has been shown to significantly improve overall survival but did not reduce the occurrence of liver metastases (SAKK 40/81) [Swiss Group for Clinical Cancer Rese...
journal_title：International journal of colorectal disease
pub_type： 杂志文章,多中心研究,随机对照试验
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更新日期：2008-12-01 00:00:00
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journal_title：International journal of colorectal disease
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journal_title：International journal of colorectal disease
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更新日期：2016-06-01 00:00:00
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journal_title：International journal of colorectal disease
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journal_title：International journal of colorectal disease
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更新日期：1992-12-01 00:00:00
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journal_title：International journal of colorectal disease
pub_type： 临床试验,杂志文章
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更新日期：2007-03-01 00:00:00
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更新日期：1997-01-01 00:00:00
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journal_title：International journal of colorectal disease
pub_type： 杂志文章,多中心研究
doi：10.1007/s00384-018-3123-6
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abstract：PURPOSE:Colorectal cancer is a common malignancy and one of the major causes of cancer-related deaths worldwide. Similar to other human cancers, tumor metastasis is the biggest obstacle in the clinical treatment of colorectal cancer. In this study, we explored the functional role of SLIT2 in colon tumor metastasis and ...
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更新日期：2013-07-01 00:00:00
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journal_title：International journal of colorectal disease
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journal_title：International journal of colorectal disease
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journal_title：International journal of colorectal disease
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更新日期：2017-03-01 00:00:00
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journal_title：International journal of colorectal disease
pub_type： 杂志文章,评审
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更新日期：2006-09-01 00:00:00
