Abstract：
PURPOSE:Persistent fecal incontinence beyond childhood is common in ARM patients. The aim of this study was to analyze a consecutive series of adult patients with persistent incontinence, establish the causes, and evaluate whether further treatment could be offered. METHODS:Forty-four adult ARM patients with reported incontinence were invited. Eighteen patients (11 males, median age 40.5 years, range 18-50 years) accepted and underwent clinical examination, rectoscopy, and 3D-ultrasound. Five had previously been treated with secondary surgery to improve continence. RESULTS:Seventeen of the 18 patients had abnormal findings at examination. Eight patients had obstruction of the reconstructed anus. Eleven patients had sacral deformities. Nine patients had a defect in the external anal sphincter and nine patients could not contract the sphincter on demand. Five patients had significant prolapse of mucosa. In one patient, the neoanus was totally misplaced, one patient had a rectovaginal fistula, and one patient had short bowel syndrome due to several small bowel resections. Ten patients were offered conservative and five surgical treatment. CONCLUSIONS:This case series of adults shows that a majority of the patients can be offered further treatment. This indicates a need for structured follow-up of ARM patients into adulthood.
journal_name
Int J Colorectal Disjournal_title
International journal of colorectal diseaseauthors
Danielson J,Karlbom U,Graf W,Wester Tdoi
10.1007/s00384-018-3220-6subject
Has Abstractpub_date
2019-03-01 00:00:00pages
551-554issue
3eissn
0179-1958issn
1432-1262pii
10.1007/s00384-018-3220-6journal_volume
34pub_type
杂志文章abstract：PURPOSE:The aim of the present study was to evaluate the IL6 -174 G>C (rs1800795) and -572 G>C (rs1800796) genetic variants and their association with inflammatory bowel diseases (IBDs), disease activity, and response to TNF-α inhibitors. METHODS:The study included 178 patients with IBD and 224 healthy controls. Among...
journal_title：International journal of colorectal disease
pub_type： 杂志文章
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journal_title：International journal of colorectal disease
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更新日期：2006-07-01 00:00:00
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journal_title：International journal of colorectal disease
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更新日期：2017-08-01 00:00:00
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journal_title：International journal of colorectal disease
pub_type： 杂志文章,meta分析
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journal_title：International journal of colorectal disease
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journal_title：International journal of colorectal disease
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journal_title：International journal of colorectal disease
pub_type： 杂志文章,评审
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更新日期：2011-08-01 00:00:00
abstract：:The biomechanical properties and intestinal wall composition of left colon were studied in 4-month-old, 14-month-old, and 27-month-old male rats. The hydroxyproline content and hydroxyproline concentration in old rats were increased by 36% and 26%, respectively, compared with young rats and by 20% and 17%, respectivel...
journal_title：International journal of colorectal disease
pub_type： 杂志文章
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journal_title：International journal of colorectal disease
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pub_type： 杂志文章,随机对照试验
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journal_title：International journal of colorectal disease
pub_type： 杂志文章
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更新日期：1992-02-01 00:00:00
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journal_title：International journal of colorectal disease
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更新日期：2019-11-01 00:00:00
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journal_title：International journal of colorectal disease
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更新日期：2012-03-01 00:00:00
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journal_title：International journal of colorectal disease
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更新日期：2009-12-01 00:00:00
abstract：:Hidradenitis suppurativa (HS) is a chronic fistula- and abscess-forming disease of the cutis and subcutis of unknown etiology. Disease recurrence is frequent and may cause severe complications. We analyzed patients with HS who underwent surgery between 1976 and 1997. The operative procedures were divided into drainage...
journal_title：International journal of colorectal disease
pub_type： 杂志文章
doi：10.1007/s003840050159
更新日期：1998-01-01 00:00:00
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journal_title：International journal of colorectal disease
pub_type： 杂志文章
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更新日期：2013-07-01 00:00:00
abstract：BACKGROUND AND AIMS:A 5-bp insertion-deletion (indel) polymorphism in the promoter of interferon regulatory factor 5 (IRF5) has been associated with inflammatory bowel diseases (IBD). This polymorphism generates an additional binding site for the transcription factor SP1 and has been shown to augment the expression of ...
journal_title：International journal of colorectal disease
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更新日期：2010-05-01 00:00:00
abstract：PURPOSE:The purpose of this study was to prospectively compare rectal resection (RR) with colonic resection on sexual, urinary and bowel function and quality of life in both short-term and long-term. METHODS:Eighty-three patients who underwent RR were compared to 53 patients who underwent a colonic resection leaving t...
journal_title：International journal of colorectal disease
pub_type： 杂志文章
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abstract：BACKGROUND:Collagenous colitis is a chronic inflammatory bowel disease of unknown origin. In some cases of collagenous colitis, histomorphological features are comparable to other inflammatory bowel diseases. AIM:To assess functional NOD2/CARD15 polymorphisms for the susceptibility to collagenous colitis in a case-con...
journal_title：International journal of colorectal disease
pub_type： 杂志文章
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更新日期：2007-04-01 00:00:00
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journal_title：International journal of colorectal disease
pub_type： 杂志文章,meta分析,评审
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更新日期：2014-01-01 00:00:00
abstract：OBJECTIVES:Inflammation is an important driver of abdominal pain in inflammatory bowel disease (IBD). However, some patients in remission still experience pain. We aimed to identify risk factors associated with abdominal pain in quiescent IBD (QP-IBD) and to characterize differences from patients with active disease ex...
journal_title：International journal of colorectal disease
pub_type： 杂志文章
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更新日期：2021-01-01 00:00:00
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journal_title：International journal of colorectal disease
pub_type： 杂志文章
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更新日期：2011-08-01 00:00:00
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journal_title：International journal of colorectal disease
pub_type： 杂志文章,meta分析,评审
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更新日期：2014-02-01 00:00:00
abstract：PURPOSE:Adjuvant chemotherapy with oxaliplatin combined with a fluoropyrimidine derivative is widely accepted as standard therapy for patients with stage III colon cancer, since few clinical data are available for Japanese patients. The FACOS trial investigated the tolerability of modified FOLFOX6 (mFOLFOX6) and XELOX ...
journal_title：International journal of colorectal disease
pub_type： 杂志文章
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更新日期：2018-06-01 00:00:00
abstract：PURPOSE:Cancerous involvement of a ureter is sometimes encountered in pelvic surgery for malignancy. We usually perform transureteroureterostomy (TUU) in cases of unilateral lower ureteral cancerous involvement. We report the outcomes in patients treated with TUU in our institute. METHODS:We retrospectively reviewed t...
journal_title：International journal of colorectal disease
pub_type： 杂志文章
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更新日期：2017-01-01 00:00:00
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journal_title：International journal of colorectal disease
pub_type： 杂志文章
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更新日期：2012-03-01 00:00:00
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journal_title：International journal of colorectal disease
pub_type： 杂志文章
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更新日期：2016-01-01 00:00:00
