当前位置： SCI文献检索 > INTERNATIONAL JOURNAL OF COLORECTAL DISEASE期刊下所有文献 > Age-related alterations in the strength and collagen content of left colon in rats.

Age-related alterations in the strength and collagen content of left colon in rats.

Abstract：

:The biomechanical properties and intestinal wall composition of left colon were studied in 4-month-old, 14-month-old, and 27-month-old male rats. The hydroxyproline content and hydroxyproline concentration in old rats were increased by 36% and 26%, respectively, compared with young rats and by 20% and 17%, respectively, compared with middle-aged rats. In middle-aged rats the maximum load increased by 21%, compared with young rats. In old rats, however, the maximum load decreased by 13%, compared with middle-aged rats. Histological examination showed that the mean crypt height was 9% higher in middle-aged rats and 12% higher in old rats than in young rats. In conclusion, an accumulation of collagenous proteins was found in old rats compared with middle-aged rats and this was accompanied by a decrease in the strength, which may deteriorate the functional integrity of the left colonic wall with age.

journal_name

Int J Colorectal Dis

journal_title

International journal of colorectal disease

authors

Christensen H,Andreassen TT,Oxlund H

doi

10.1007/BF00341292

subject

Has Abstract

pub_date

1992-06-01 00:00:00

pages

85-8

issue

2

eissn

0179-1958

issn

1432-1262

journal_volume

7

pub_type

杂志文章

相关文献

INTERNATIONAL JOURNAL OF COLORECTAL DISEASE文献大全
  • Serum biochemical evaluation of patients with functional pouches ten to 20 years after restorative proctocolectomy.

    abstract：BACKGROUND:Restorative proctocolectomy with an ileal pouch-anal anastomosis is a surgical treatment of choice for ulcerative colitis and familial adenomatous polyposis (FAP). Pouchitis is a significant enigmatic morbidity. In the long-term, these patients, we anticipated, would experience biochemical profiling alterati...

    journal_title：International journal of colorectal disease

    pub_type： 杂志文章

    doi：10.1007/s00384-005-0076-3

    authors： M'Koma AE

    更新日期：2006-10-01 00:00:00

  • Timing of surgery in ulcerative colitis in the biologic therapy era-the patient's perspective.

    abstract：BACKGROUND:There is no general consensus regarding the ideal timing of surgery in patients with refractory ulcerative colitis (UC). Decision-making and timing of restorative proctocolectomy with ileal pouch-anal anastomosis (IPAA) is influenced by treating physicians and patients themselves. The aim of this study was t...

    journal_title：International journal of colorectal disease

    pub_type： 杂志文章

    doi：10.1007/s00384-018-3129-0

    authors： Gröne J,Lorenz EM,Seifarth C,Seeliger H,Kreis ME,Mueller MH

    更新日期：2018-10-01 00:00:00

  • Next-generation narrow band imaging system for colonic polyp detection: a prospective multicenter randomized trial.

    abstract：PURPOSE:Previous studies have yielded conflicting results on the colonic polyp detection rate with narrow-band imaging (NBI) compared with white-light imaging (WLI). We compared the mean number of colonic polyps detected per patient for NBI versus WLI using a next-generation NBI system (EVIS LUCERA ELITE; Olympus Medic...

    journal_title：International journal of colorectal disease

    pub_type： 杂志文章,多中心研究,随机对照试验

    doi：10.1007/s00384-015-2230-x

    authors： Horimatsu T,Sano Y,Tanaka S,Kawamura T,Saito S,Iwatate M,Oka S,Uno K,Yoshimura K,Ishikawa H,Muto M,Tajiri H

    更新日期：2015-07-01 00:00:00

  • Robotic rectal cancer surgery in obese patients may lead to better short-term outcomes when compared to laparoscopy: a comparative propensity scored match study.

    abstract：PURPOSE:Laparoscopic rectal surgery in obese patients is technically challenging. The technological advantages of robotic instruments can help overcome some of those challenges, but whether this translates to superior short-term outcomes is largely unknown. The aim of this study is to compare the short-term surgical ou...

    journal_title：International journal of colorectal disease

    pub_type： 杂志文章

    doi：10.1007/s00384-018-3030-x

    authors： Panteleimonitis S,Pickering O,Abbas H,Harper M,Kandala N,Figueiredo N,Qureshi T,Parvaiz A

    更新日期：2018-08-01 00:00:00

  • Association between increased tumor necrosis factor alpha levels and acquired activated protein C resistance in patients with metastatic colorectal cancer.

    abstract：PURPOSE:The purpose of this study was to investigate the possible association between tumor necrosis factor-α (TNF-α) levels and defects in the activated protein C (APC) system as a determinant of venous thromboembolism (VTE) in metastatic colorectal cancer patients (mCRC) undergoing chemotherapy. METHODS:TNF-α levels...

    journal_title：International journal of colorectal disease

    pub_type： 杂志文章

    doi：10.1007/s00384-012-1493-8

    authors： Ferroni P,Riondino S,Portarena I,Formica V,La Farina F,Martini F,Massimiani G,Palmirotta R,Guadagni F,Roselli M

    更新日期：2012-12-01 00:00:00

  • Extended mesenteric excision in right hemicolectomy for carcinoma of the colon.

    abstract：:Between 1979 and 1989, 169 patients had a curative operation for right sided colonic cancer. A retrospective analysis of the incidence and degree of lymph node metastasis was performed in all and survival rate was determined in 144 patients who could be followed over a period of 5 years or more. In all patients, disse...

    journal_title：International journal of colorectal disease

    pub_type： 杂志文章

    doi：10.1007/s003840050104

    authors： Tagliacozzo S,Tocchi A

    更新日期：1997-01-01 00:00:00

  • Long-term outcomes after treatment for T1 colorectal carcinoma.

    abstract：PURPOSE:Long-term outcomes of patients with T1 colorectal carcinoma (CRC) treated by endoscopic resection (ER) or surgical resection are unclear in relation to the curative criteria in the Japanese Society for Cancer of the Colon and Rectum (JSCCR) guidelines. The aim of this study was to retrospectively compare the lo...

    journal_title：International journal of colorectal disease

    pub_type： 杂志文章

    doi：10.1007/s00384-015-2473-6

    authors： Asayama N,Oka S,Tanaka S,Ninomiya Y,Tamaru Y,Shigita K,Hayashi N,Egi H,Hinoi T,Ohdan H,Arihiro K,Chayama K

    更新日期：2016-03-01 00:00:00

  • Positive effects of phenytoin on experimental colonic anastomoses.

    abstract：BACKGROUND AND AIMS:Anastomotic dehiscence following colorectal surgery is a significant cause of morbidity and mortality. Phenytoin has wound-healing promoting and collagenase inhibitory effects. This study assessed these effects on healing of experimental colonic anastomoses in a rat model. MATERIALS AND METHODS:Nin...

    journal_title：International journal of colorectal disease

    pub_type： 杂志文章

    doi：10.1007/s00384-003-0533-9

    authors： Turan M,Saraydin SU,Canbay E,Karadayi K,Bulut E,Cetinkaya O,Elagöz S,Sen M

    更新日期：2004-05-01 00:00:00

  • Indocyanine green fluorescent imaging on anastomotic leakage in colectomies: a network meta-analysis and systematic review.

    abstract：PURPOSE:The usage of indocyanine green (ICG) dye is commonly associated with decreased anastomotic leakage rates in colectomies. This study aims to perform a network meta-analysis to assess the usage of ICG fluorescence imaging in right-sided colectomies. METHODS:Medline, Embase, Cochrane Trials, CNKI, and WanFang ele...

    journal_title：International journal of colorectal disease

    pub_type： 杂志文章

    doi：10.1007/s00384-020-03723-7

    authors： Mok HT,Ong ZH,Yaow CYL,Ng CH,Buan BJL,Wong NW,Chong CS

    更新日期：2020-12-01 00:00:00

  • Flexible endoscopy is enough diagnostic prior to loop ileostomy reversal.

    abstract：PURPOSE:This study investigates whether contrast enema (CE) and flexible endoscopy (FE) should be performed routinely after low anterior resection (LAR) before ileostomy reversal. Additionally, the impact of previous anastomotic leakage (AL) on diagnostic test accuracy (DTA) was assessed. METHODS:This is a retrospecti...

    journal_title：International journal of colorectal disease

    pub_type： 杂志文章

    doi：10.1007/s00384-020-03766-w

    authors： Lindner S,von Rudno K,Gawlitza J,Hardt J,Sandra-Petrescu F,Seyfried S,Kienle P,Reissfelder C,Bogner A,Herrle F

    更新日期：2021-02-01 00:00:00

  • Predictive parameters for the clinical course of Crohn's disease: development of a simple and reliable risk model.

    abstract：PURPOSE:The aim of our study was to identify clinical parameters in recently diagnosed Crohn's disease (CD) patients for prediction of their disease course. METHODS:EPIC (Early Predictive parameters of Immunosuppressive therapy in Crohn's disease) is a prospective, observational study in 341 patients with a recent CD ...

    journal_title：International journal of colorectal disease

    pub_type： 杂志文章

    doi：10.1007/s00384-019-03369-0

    authors： Stallmach A,Bokemeyer B,Helwig U,Lügering A,Teich N,Fischer I,Rath S,Lang D,Schmidt C,EPIC Study Group.

    更新日期：2019-10-01 00:00:00

  • Study protocol for a multicenter prospective controlled and randomized trial of transanal total mesorectal excision versus laparoscopic low anterior resection in rectal cancer.

    abstract：PURPOSE:Compared with the open approach, laparoscopic total mesorectal excision (TME) achieves faster patient recovery, reduces morbidity rates, and shortens hospital stay. However, in laparoscopic low anterior resection (L-LAR), conversion to open surgery is required in almost 20% of cases. Transanal TME (Ta-TME) comb...

    journal_title：International journal of colorectal disease

    pub_type： 杂志文章,多中心研究,随机对照试验

    doi：10.1007/s00384-018-2996-8

    authors： Serra-Aracil X,Zárate A,Mora L,Serra-Pla S,Pallisera A,Bonfill J,Bargalló J,Pando A,Delgado S,Balleteros E,Pericay C

    更新日期：2018-05-01 00:00:00

  • Pattern of recurrence in rectal carcinoma: implications for the design of (future) studies on adjuvant therapy.

    abstract：:255 patients who underwent potentially curative surgical treatment for rectal carcinoma at the Cantonal Hospital Aarau from 1981 to 1989 have been followed up and the results analysed for overall survival and the timing and occurrence of local and distant recurrence in relation to the initial tumor stage. The patients...

    journal_title：International journal of colorectal disease

    pub_type： 杂志文章

    doi：10.1007/BF00341187

    authors： Barras JP,Bachmann R,Aeberhard P

    更新日期：1993-09-01 00:00:00

  • The insulin-like growth factor system and colorectal cancer: clinical and experimental evidence.

    abstract：OBJECTIVE:The aim of this review is to clarify the involvement of the insulin-like growth factor (IGF) system in the development of colorectal malignancy. MATERIALS AND METHODS:Medline searches were used to identify key articles relating the IGF system with the development of colorectal cancer. RESULTS:The IGF system...

    journal_title：International journal of colorectal disease

    pub_type： 杂志文章,评审

    doi：10.1007/s00384-005-0776-8

    authors： Davies M,Gupta S,Goldspink G,Winslet M

    更新日期：2006-04-01 00:00:00

  • Laparoscopic adult colorectal surgeon and adolescents with inflammatory bowel disease: a safe combination?

    abstract：INTRODUCTION:A multidisciplinary tertiary service for adolescents with inflammatory bowel disease (IBD) was commenced in April 2008, aiming to provide specialist treatment for adolescent patients and bridge the gap between existing paediatric and adult surgical services. A single laparoscopic colorectal surgeon who nor...

    journal_title：International journal of colorectal disease

    pub_type： 临床试验,杂志文章

    doi：10.1007/s00384-010-1058-7

    authors： Courtney ED,Brennan M,Noble-Jamieson G,Heuschkel R,Davies RJ

    更新日期：2011-03-01 00:00:00

  • (E)-metanicotine hemigalactarate (TC-2403-12) inhibits IL-8 production in cells of the inflamed mucosa.

    abstract：BACKGROUND:Nicotine is of therapeutic value in ulcerative colitis, but its administration is connected with adverse events. Nicotine derivatives are currently being tested to maintain the therapeutic effects and minimize adverse events. TC-2403-12 is a (E)-metanicotine hemigalactarate. The aim of this study was to dete...

    journal_title：International journal of colorectal disease

    pub_type： 杂志文章

    doi：10.1007/s00384-006-0135-4

    authors： Spoettl T,Paetzel C,Herfarth H,Bencherif M,Schoelmerich J,Greinwald R,Gatto GJ,Rogler G

    更新日期：2007-03-01 00:00:00

  • The role of protein kinase CK2 in intestinal epithelial cell inflammatory signaling.

    abstract：BACKGROUND:The transcription factor NF-kappaB is believed to play a key pathophysiological role in chronic intestinal inflammation. Further characterization of its mechanism of regulation, predominantly through cell signaling pathways, may provide clues as to the means of its intervention. One such potential signaling ...

    journal_title：International journal of colorectal disease

    pub_type： 杂志文章

    doi：10.1007/s00384-006-0193-7

    authors： Parhar K,Morse J,Salh B

    更新日期：2007-06-01 00:00:00

  • HPV-associated anal lesions in HIV+ patients: long-term results regarding quality of life.

    abstract：PURPOSE:HIV infection and concomitant HPV-associated anal lesions may significantly impact on patients' quality of life (QoL), as they are predicted to have negative effects on health, psyche, and sexuality. MATERIAL AND METHODS:Fifty-two HIV+ patients with HPV-associated anal lesions were enrolled in a survey approac...

    journal_title：International journal of colorectal disease

    pub_type： 杂志文章

    doi：10.1007/s00384-020-03567-1

    authors： Wesselmann P,Schwarze-Zander C,Boesecke C,Rockstroh J,Stoffels B,Vilz TO,Glowka TR,Kalff JC,von Websky MW

    更新日期：2020-06-01 00:00:00

  • RET-protooncogene variants in patients with sporadic neoplasms of the digestive tract and the central nervous system.

    abstract：PURPOSE:The RET protooncogene plays a crucial role in neural crest development; accordingly, mutations of RET cause MEN2A and familial medullary thyroid carcinoma, while the expression deregulation of RET is involved in the pathophysiology of glioblastoma multiforme (GBM) and pancreatic cancer (PDAC). The aim of this s...

    journal_title：International journal of colorectal disease

    pub_type： 杂志文章

    doi：10.1007/s00384-011-1150-7

    authors： Rückert F,Görgens H,Richter I,Krex D,Schackert G,Kuhlisch E,Fitze G,Saeger HD,Pilarsky C,Grützmann R,Schackert HK

    更新日期：2011-07-01 00:00:00

  • The predictive value of metabolic response to preoperative radiochemotherapy in locally advanced rectal cancer measured by PET/CT.

    abstract：BACKGROUND:To evaluate the value of positron emission tomography using fluorodeoxyglucose and computer tomography scan (FDG-PET/CT) for prediction of histopathological response of preoperative radiochemotherapy (RCTX) in patients with rectal carcinoma. METHODS:Thirty patients with uT3 rectal carcinoma were examined by...

    journal_title：International journal of colorectal disease

    pub_type： 临床试验,杂志文章

    doi：10.1007/s00384-008-0616-8

    authors： Rosenberg R,Herrmann K,Gertler R,Künzli B,Essler M,Lordick F,Becker K,Schuster T,Geinitz H,Maak M,Schwaiger M,Siewert JR,Krause B

    更新日期：2009-02-01 00:00:00

  • Conversion during laparoscopic colorectal resections: a complication or a drawback? A systematic review and meta-analysis of short-term outcomes.

    abstract：PURPOSE:Several studies compared the outcomes of laparoscopically completed colorectal resections (LCR) to those requiring conversion to open surgery (COS). However, a comparative analysis between COS patients and patients undergoing planned open surgery (POS) would be useful to clarify if the conversion can be conside...

    journal_title：International journal of colorectal disease

    pub_type： 杂志文章,meta分析,评审

    doi：10.1007/s00384-015-2324-5

    authors： Giglio MC,Celentano V,Tarquini R,Luglio G,De Palma GD,Bucci L

    更新日期：2015-11-01 00:00:00

  • Outpatient, non-antibiotic management in acute uncomplicated diverticulitis: a prospective study.

    abstract：PURPOSE:The aim of this study was to evaluate outpatient, non-antibiotic management in acute uncomplicated diverticulitis with regard to admissions, complications, and recurrences, within a 3-month follow-up period. METHODS:A prospective, observational study in which patients with computer tomography-verified acute un...

    journal_title：International journal of colorectal disease

    pub_type： 杂志文章

    doi：10.1007/s00384-015-2258-y

    authors： Isacson D,Thorisson A,Andreasson K,Nikberg M,Smedh K,Chabok A

    更新日期：2015-09-01 00:00:00

  • Impact of implementation of the ERAS program in colorectal surgery: a multi-center study based on the "Lazio Network" collective database.

    abstract：BACKGROUND:ERAS implementation improved outcomes in patients undergoing colorectal surgery. The process of incorporating this pathway in clinical practice may be challenging. This observational study investigated the impact of systematic ERAS implementation on surgical outcomes in patients undergoing colorectal resecti...

    journal_title：International journal of colorectal disease

    pub_type： 杂志文章,多中心研究

    doi：10.1007/s00384-019-03496-8

    authors： Grieco M,Lorenzon L,Pernazza G,Carlini M,Brescia A,Santoro R,Crucitti A,Palmieri RM,Santoro E,Stipa F,Sacchi M,Persiani R

    更新日期：2020-03-01 00:00:00

  • Surgical aspects of inflammatory bowel diseases in pediatric and adolescent age groups.

    abstract：BACKGROUND:Inflammatory bowel disease (IBD) is increasingly encountered in children. Early disease is associated with higher complication rate with increased incidence of surgical intervention. PATIENTS AND METHODS:From January 2010 to June 2015, 25 patients in the pediatric and adolescent age groups with IBD underwen...

    journal_title：International journal of colorectal disease

    pub_type： 杂志文章

    doi：10.1007/s00384-015-2388-2

    authors： El-Asmar K,El-Shafei E,Abdel-Latif M,AbouZeid A,El-Behery M

    更新日期：2016-02-01 00:00:00

  • Risk factors and clinical courses of concomitant primary sclerosing cholangitis and ulcerative colitis: a Korean multicenter study.

    abstract：BACKGROUND:Primary sclerosing cholangitis (PSC) is a rare progressive cholestatic liver disease of unknown causes, but is strongly associated with inflammatory bowel diseases (IBDs), particularly ulcerative colitis (UC). However, studies comparing risk factors and clinical courses of patients with concomitant UC and PS...

    journal_title：International journal of colorectal disease

    pub_type： 杂志文章,多中心研究

    doi：10.1007/s00384-018-3123-6

    authors： Park YE,Cheon JH,Park JJ,Kim YJ,Choi CH,Park Y,Park SJ,Kim TI,Kim WH

    更新日期：2018-10-01 00:00:00

  • Total abdominal colectomy vs. restorative total proctocolectomy as the initial approach to medically refractory ulcerative colitis.

    abstract：PURPOSE:There is scant data assessing the consequences of staging restorative proctocolectomy for ulcerative colitis. The aim of the study is to compare outcomes of initial vs. staged restorative proctocolectomy. METHODS:Patients completing restorative proctocolectomy, including ileostomy reversal, during 2006-2012 we...

    journal_title：International journal of colorectal disease

    pub_type： 杂志文章

    doi：10.1007/s00384-017-2836-2

    authors： Gu J,Stocchi L,Ashburn J,Remzi FH

    更新日期：2017-08-01 00:00:00

  • Post-operative clinical, manometric, and defecographic findings in patients undergoing unsuccessful STARR operation for obstructed defecation.

    abstract：AIM:To evaluate the reason for failure of STARR (stapled transanal rectal resection) operation for obstructed defecation. METHODS:A retrospective study (June 2012-December 2017) was performed using a prospectively maintained database of patients who underwent STARR operation for ODS (obstructed defecation syndrome), c...

    journal_title：International journal of colorectal disease

    pub_type： 杂志文章

    doi：10.1007/s00384-019-03263-9

    authors： Picciariello A,Papagni V,Martines G,De Fazio M,Digennaro R,Altomare DF

    更新日期：2019-05-01 00:00:00

  • Getting the first degree relatives to screen for colorectal cancer is harder than it seems-patients' and their first degree relatives' perspectives.

    abstract：INTRODUCTION:First degree relatives (FDR) of colorectal cancer (CRC) patients are at increased risk of CRC compared to the general population. However, screening colonoscopy rates amongst the FDRs remain dismal. The aim of the study was to explore the various issues amongst the patients and their FDR precluding their a...

    journal_title：International journal of colorectal disease

    pub_type： 杂志文章

    doi：10.1007/s00384-017-2818-4

    authors： Tan KK,Lim TZ,Chan DKH,Chew E,Chow WM,Luo N,Wong ML,Koh GC

    更新日期：2017-07-01 00:00:00

  • Comparison of two sodium phosphate tablet-based regimens and a polyethylene glycol regimen for colon cleansing prior to colonoscopy: a randomized prospective pilot study.

    abstract：PURPOSE:The aim of this pilot study was to compare the performance and safety of the newly developed sodium phosphate (NaP) tablet (with and without laxatives) and polyethylene glycol (PEG), as bowel-cleansing regimens prior to colonoscopy. METHODS:A total of 35 patients were randomized to one of the following three g...

    journal_title：International journal of colorectal disease

    pub_type： 杂志文章,随机对照试验

    doi：10.1007/s00384-009-0735-x

    authors： Aihara H,Saito S,Arakawa H,Imazu H,Omar S,Kaise M,Tajiri H

    更新日期：2009-09-01 00:00:00

  • Chronic posterior tibial nerve transcutaneous electrical nerve stimulation (TENS) to treat fecal incontinence (FI).

    abstract：AIM:Transcutaneous electrical nerve stimulation (TENS) is a possible alternative to sacral nerve stimulation because the neurophysiologic targets might be similar but the former method is non-invasive and cheaper. The aim of the study was to assess both symptom and quality of life (QoL) improvements in patients sufferi...

    journal_title：International journal of colorectal disease

    pub_type： 临床试验,杂志文章

    doi：10.1007/s00384-010-0960-3

    authors： Eléouet M,Siproudhis L,Guillou N,Le Couedic J,Bouguen G,Bretagne JF

    更新日期：2010-09-01 00:00:00