Abstract：
PURPOSE:Long-term outcomes of patients with T1 colorectal carcinoma (CRC) treated by endoscopic resection (ER) or surgical resection are unclear in relation to the curative criteria in the Japanese Society for Cancer of the Colon and Rectum (JSCCR) guidelines. The aim of this study was to retrospectively compare the long-term outcomes among patients with T1 CRC in relation to the treatment methods. METHODS:We examined 322 T1 CRC cases treated between January 1992 and August 2008 at Hiroshima University Hospital. Patients who did not meet the curative criteria in the JSCCR guidelines were defined as "non-endoscopically curable" and classified into three groups: underwent ER alone (group A: 45 patients), underwent additional surgery after ER (group B: 106 patients), and underwent surgical resection alone (group C: 92 patients). RESULTS:Of the 322 T1 CRC patients, 79 were categorized as endoscopically curable and 243 as non-endoscopically curable. Among the endoscopically curable T1 CRC patients, recurrence and 5-year OS rates were 0 and 94.2%, respectively. In groups A, B, and C, recurrence rates were 4.4, 6.6, and 4.3%, and OS rates were 85.6, 95.1, and 96.3%, respectively (p < 0.05). Local recurrence or distant/lymph node metastasis was observed in 13 patients (group A: 2; group B: 7; group C: 4). Death due to primary CRC occurred in six patients (group B: 4; group C: 2). CONCLUSION:Long-term outcomes support the curative criteria according to the JSCCR guidelines. ER for T1 CRC did not worsen clinical outcomes in cases that required additional surgical resection.
journal_name
Int J Colorectal Disjournal_title
International journal of colorectal diseaseauthors
Asayama N,Oka S,Tanaka S,Ninomiya Y,Tamaru Y,Shigita K,Hayashi N,Egi H,Hinoi T,Ohdan H,Arihiro K,Chayama Kdoi
10.1007/s00384-015-2473-6subject
Has Abstractpub_date
2016-03-01 00:00:00pages
571-8issue
3eissn
0179-1958issn
1432-1262pii
10.1007/s00384-015-2473-6journal_volume
31pub_type
杂志文章abstract：PURPOSE:The current study aimed to compare the oncologic outcome and pattern of metastasis after abdominoperineal resection (APR) and low anterior resection (LAR) treating lower rectal cancer. METHODS:A total of 804 patients undergoing curative resection (R0) were enrolled prospectively. The APR and LAR groups (n = 40...
journal_title：International journal of colorectal disease
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abstract：AIM:Psychological stress is known to affect the immunologic system and the inflammatory response. The aim of this study was to assess the presence of psychological stress, anxiety, and depression in patients with anal fistula. METHODS:Consecutive patients with anal fistula, hemorrhoids, and normal volunteers were stud...
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abstract：AIM:An illustration of the diagnosis and management of tailgut cysts. MATERIALS AND METHODS:Two cases of tailgut cyst and a review of the literature. RESULTS:A female patient presented with acute urinary retention with a retrorectal mass felt during rectal examination and confirmed on ultrasound and magnetic resonanc...
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journal_title：International journal of colorectal disease
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