Is ascites CEA a risk factor for peritoneal carcinomatosis in colorectal cancer?: a long-term follow-up study.

abstract：PURPOSE:The aim of this study is to evaluate the influence of germline vascular endothelial growth factor (VEGF) gene polymorphisms (VGPs) on the efficacy of the anti-VEGF antibody bevacizumab (Bev) in metastatic colorectal cancer (MCRC) patients. METHODS:Forty MCRC patients eligible for a first-line therapy were enro...

journal_title：International journal of colorectal disease

authors： Formica V,Palmirotta R,Del Monte G,Savonarola A,Ludovici G,De Marchis ML,Grenga I,Schirru M,Guadagni F,Roselli M

更新日期：2011-02-01 00:00:00

abstract：PURPOSE:Sound speed correction (SSC) is a non-invasive modality that quantifies the hardness of neoplasms. The aim of our study was to evaluate the usefulness of SSC for the diagnostic accuracy of colorectal neoplasms and to differentiate the depth of invasion. METHODS:Forty colorectal neoplasms, contributed by 40 pat...

journal_title：International journal of colorectal disease

authors： Esaki M,Yamamura T,Nakamura M,Maeda K,Sawada T,Mizutani Y,Ishikawa E,Furukawa K,Kawashima H,Hirooka Y,Fujishiro M

更新日期：2020-10-28 00:00:00

abstract：PURPOSE:Tumor grade is a traditional prognostic parameter in colorectal cancer. Remarkably, however, there is still no generally accepted consensus how to perform tumor grading. In this study, we systematically compared the prognostic value of traditional grading based upon histological features, that is, gland formati...

journal_title：International journal of colorectal disease

authors： Resch A,Harbaum L,Pollheimer MJ,Kornprat P,Lindtner RA,Langner C

更新日期：2016-03-01 00:00:00

abstract：PURPOSE:Serological tumor markers are routinely used to monitor tumor onset and progression. In colorectal carcinoma (CRC), the carcinoembryonic antigen (CEA) is roughly elevated in 50% of patients at initial diagnosis. Soluble ICAM-1 (sICAM-1) is elevated in different cancers. The aim of this study was to evaluate the...

journal_title：International journal of colorectal disease

authors： Schellerer VS,Langheinrich MC,Zver V,Grützmann R,Stürzl M,Gefeller O,Naschberger E,Merkel S

更新日期：2019-02-01 00:00:00

abstract：INTRODUCTION:Although advances in multimodal treatment have led to prolongation of survival in patients after resection of colorectal liver metastasis (CRC-LM), most patients develop recurrence, which is often confined to the liver. Repeat hepatic resection (RHR) may prolong survival or even provide cure in selected pa...

journal_title：International journal of colorectal disease

authors： Neeff HP,Drognitz O,Holzner P,Klock A,Bronsert P,Hopt UT,Makowiec F

更新日期：2013-08-01 00:00:00

abstract：PURPOSE:The effects of ulcerative colitis (UC) duration on biomarker accuracy are unknown. We investigated the effects of UC duration on the predictive accuracy of biomarkers including immunochemical fecal occult blood test (FOBT, also known as FIT), prostaglandin E-major urinary metabolite (PGE-MUM), and C-reactive pr...

journal_title：International journal of colorectal disease

authors： Ishida N,Miyazu T,Matsuura T,Takano R,Tamura S,Kagami T,Tani S,Yamade M,Hamaya Y,Iwaizumi M,Osawa S,Furuta T,Sugimoto K

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND:Postoperative ileus is a significant clinical challenge lacking effective management strategies. Ghrelin-receptor stimulation has promotility effects in the upper and lower gastrointestinal tract. OBJECTIVE:This proof-of-concept, phase 2, randomized study evaluated the safety and efficacy of the ghrelin-rec...

journal_title：International journal of colorectal disease

authors： Beck DE,Sweeney WB,McCarter MD,Ipamorelin 201 Study Group.

更新日期：2014-12-01 00:00:00

abstract：PURPOSES:Carcinoids are heterogeneous neuroendocrine tumors with malignant potential. The rectum is the third most common location for gastrointestinal carcinoids. We assessed the clinicopathological characteristics of rectal carcinoids. METHODS:A retrospective study of 203 patients treated for rectal carcinoids at th...

journal_title：International journal of colorectal disease

authors： Yoon SN,Yu CS,Shin US,Kim CW,Lim SB,Kim JC

更新日期：2010-09-01 00:00:00

abstract：BACKGROUND:Several studies have confirmed that laparoscopic colorectal surgery results in improved early post-operative outcomes. Nevertheless, conventional laparoscopic approach and instruments have several limitations. Robotic approach could potentially address of many of these limitations. OBJECTIVES:This review ai...

journal_title：International journal of colorectal disease

authors： Aly EH

更新日期：2014-01-01 00:00:00

abstract：:Leukocyte emigration from blood to sites of inflammation involves sequential interaction of specific adhesion molecules expressed by both leukocytes and endothelial cells. The central steps in leukocyte-endothelial adhesive interactions are leukocyte rolling, sticking, and transmigration. This study investigated the e...

journal_title：International journal of colorectal disease

authors： Krieglstein CF,Anthoni C,Laukötter MG,Rijcken E,Spiegel HU,Senninger N,Schürmann G

更新日期：1999-11-01 00:00:00

abstract：PURPOSE:The objectives of the study were to estimate the incidence and clarify the clinicopathologic feature of sporadic microsatellite instability (MSI)-high (MSI-H) colon cancer. Furthermore, the role of MSI in colon cancer prognosis was also investigated. METHODS:Microsatellite status was identified by genotyping. ...

journal_title：International journal of colorectal disease

authors： Lin CC,Lai YL,Lin TC,Chen WS,Jiang JK,Yang SH,Wang HS,Lan YT,Liang WY,Hsu HM,Lin JK,Chang SC

更新日期：2012-03-01 00:00:00

abstract：:We report an audit of outcome on 24 patients (16 females) who had a strictureplasty to treat ileo-colic anastomotic strictures. All except one patient had their original resection for Crohn's disease, and required reoperation because of symptoms of recurrent intestinal obstruction for a mean 9.3 months (range 1-36); t...

journal_title：International journal of colorectal disease

authors： Sharif H,Alexander-Williams J

更新日期：1991-11-01 00:00:00

abstract：:Hysterectomy is associated with severe constipation in a subgroup of patients, and an adverse effect on colonic motility has been described in the literature. The onset of irritable bowel syndrome and urinary bladder dysfunction has also been reported after hysterectomy. In this prospective study, we investigated the ...

journal_title：International journal of colorectal disease

authors： Kelly JL,O'Riordain DS,Jones E,Alawi E,O'Riordain MG,Kirwan WO

更新日期：1998-01-01 00:00:00

abstract：PURPOSE:Anorectal manometry provides objective information about anorectal function, but its results depend on the examiner's skill, the type of equipment, and subject characteristics like age or gender. This single institution, prospective study was performed to investigate the effect of gender and age on the results ...

journal_title：International journal of colorectal disease

authors： Lee HR,Lim SB,Park JY

更新日期：2014-11-01 00:00:00

abstract：PURPOSE:Secondary non-response to infliximab (IFX) in patients with Crohn's disease (CD) is so common that prediction of non-response is required to adopt the optimal therapy for an individual patient. METHODS:The clinical model was constructed in a training cohort. Clinical features, serological parameters, and genet...

journal_title：International journal of colorectal disease

authors： Xu L,Shen J,Zheng Q

更新日期：2020-11-01 00:00:00

abstract：PURPOSE:The hypothesis in this study was that anaemia prior to surgery and perioperative red blood cell transfusion increases the risk for recurrence and overall mortality in patients with stages I-III colorectal cancer after abdominal resection with curative intent. METHODS:This is a Swedish single centre retrospecti...

journal_title：International journal of colorectal disease

authors： Mörner ME,Edgren G,Martling A,Gunnarsson U,Egenvall M

更新日期：2017-02-01 00:00:00

abstract：PURPOSE:To study the distribution of subtypes and symptoms of fecal incontinence in the general Dutch population. METHODS:We performed a cross-sectional study in a representative sample of the general Dutch population. All respondents (N = 1259) completed the Groningen Defecation and Fecal Continence questionnaire. We...

journal_title：International journal of colorectal disease

authors： van Meegdenburg MM,Meinds RJ,Trzpis M,Broens PMA

更新日期：2018-07-01 00:00:00

abstract：:The heterogeneity in the DNA content was analysed in multiple biopsies from the surgical specimens in 77 cases of colonic and 46 cases of rectal adenocarcinomas. Frozen and unfixed tumour tissue was analysed with the flow cytometric technique. A total of 78/123 (63%) of all tumours displayed aneuploid stemlines in one...

journal_title：International journal of colorectal disease

authors： Lindmark G,Glimelius B,Påhlman L,Enblad P

更新日期：1991-05-01 00:00:00

abstract：:Enterovesical fistula is a relatively rare condition in Crohn's disease. This study was undertaken to examine clinicopathological features and management of enterovesical fistula complicating Crohn's disease. Thirty patients with enterovesical fistula complicating Crohn's disease, treated between 1970 and 1997, were r...

journal_title：International journal of colorectal disease

authors： Yamamoto T,Keighley MR

更新日期：2000-08-01 00:00:00

abstract：AIM:An illustration of the diagnosis and management of tailgut cysts. MATERIALS AND METHODS:Two cases of tailgut cyst and a review of the literature. RESULTS:A female patient presented with acute urinary retention with a retrorectal mass felt during rectal examination and confirmed on ultrasound and magnetic resonanc...

journal_title：International journal of colorectal disease

authors： Au E,Anderson O,Morgan B,Alarcon L,George ML

更新日期：2009-03-01 00:00:00

abstract：BACKGROUND:Some patients with uncomplicated diverticulitis have extraluminal air. Our objective was to determine if patients with Hinchey 1a diverticulitis and isolated extraluminal air present more severe episode than patients without extraluminal air. METHODS:The present study is a monocentric observational retrospe...

journal_title：International journal of colorectal disease

authors： Meyer J,Caruso A,Roos E,Balaphas A,Toso C,Poletti PA,Ris F,Buchs NC

更新日期：2019-12-01 00:00:00

abstract：PURPOSE:The main operative method in familial adenomatous polyposis (FAP) patients is restorative proctocolectomy with "J"-shaped pouch and temporary loop ileostomy. The aim of the study was the analysis of the frequency of the dysplasia and inflammation in the intestinal pouch and prognosis of the clinical course in F...

journal_title：International journal of colorectal disease

authors： Banasiewicz T,Marciniak R,Kaczmarek E,Krokowicz P,Paszkowski J,Lozynska-Nelke A,Gronek P,Plawski A,Drews M

更新日期：2011-09-01 00:00:00

abstract：PURPOSE:Ileal pouch-anal anastomosis (IPAA) has been established as the procedure of choice for patients who require excision of the colon and rectum for familial adenomatous polyposis and ulcerative colitis. The requirement for proximal stomal diversion in IPAA is controversial. OBJECTIVES:To compare post-operative o...

journal_title：International journal of colorectal disease

authors： Khan K,Manzoor T,Khan S,Hartley JE

更新日期：2021-01-04 00:00:00

abstract：PURPOSE:Due to diagnostic advancements, preoperative staging of rectal tumors was significantly improved. However, difficulties in obtaining accurate results can sometimes be observed in the staging of adenomas and early rectal carcinomas (pT1/2). The aim of this study was to test if confocal chromolaser endomicroscopy...

journal_title：International journal of colorectal disease

authors： Borschitz T,Kiesslich R

更新日期：2010-01-01 00:00:00

abstract：PURPOSE:Anastomotic leak (AL) in colorectal surgery leads to significant morbidity, mortality and poorer oncological outcomes. Diagnosis of AL is frequently delayed as current methods of detection are not 100% sensitive or specific. 'Biomarkers', such as cytokines and markers of ischaemia, from the milieu of the anasto...

journal_title：International journal of colorectal disease

authors： Wright EC,Connolly P,Vella M,Moug S

更新日期：2017-07-01 00:00:00

abstract：BACKGROUND:Diversion colitis (DC) seems to be common in stoma patients, and the restoration of the continuity of the digestive tract is crucial for relief from the inflammatory process. No prospective studies of the late effects of DC on the lower gastrointestinal (GI) tract mucosa and the clinical condition of patient...

journal_title：International journal of colorectal disease

authors： Szczepkowski M,Banasiewicz T,Kobus A

更新日期：2017-08-01 00:00:00

abstract：:Anal fissure is a common condition affecting young to middle-aged adults. It causes severe pain on defecation and rectal bleeding. The aetiology remains uncertain. Spasm of the internal anal sphincter is a constant feature. Nitric oxide (NO) is the major inhibitory neurotransmitter of the internal anal sphincter (IAS)...

journal_title：International journal of colorectal disease

authors： Lund JN

更新日期：2006-10-01 00:00:00

abstract：PURPOSE:Adjuvant chemotherapy with oxaliplatin combined with a fluoropyrimidine derivative is widely accepted as standard therapy for patients with stage III colon cancer, since few clinical data are available for Japanese patients. The FACOS trial investigated the tolerability of modified FOLFOX6 (mFOLFOX6) and XELOX ...

journal_title：International journal of colorectal disease

authors： Kosugi C,Koda K,Ishibashi K,Yoshimatsu K,Tanaka S,Kato R,Kato H,Oya M,Narushima K,Mori M,Shuto K,Ishida H

更新日期：2018-06-01 00:00:00

abstract：BACKGROUND:Patients with Lynch syndrome (LS) are at an increased risk of developing gastric cancer. In 2010, a guideline that recommended to screen all patients for Helicobacter pylori was implemented in the Netherlands. H. pylori is an important risk factor in the development of gastric cancer in the general populatio...

journal_title：International journal of colorectal disease

authors： Soer EC,Leicher LW,Langers AM,van de Meeberg PC,van der Wouden EJ,Koornstra JJ,Bigirwamungu-Bargeman M,Vasen HF,de Vos tot Nederveen Cappel WH

更新日期：2016-03-01 00:00:00

abstract：PURPOSE:Malignant bowel obstruction is a complication of colorectal carcinoma or metastasis from other carcinoma, and it causes significant damage on the condition of elderly patients; however, the self-expandable metallic stents (SEMSs) have been effectively used either for palliation or for bridging to the surgical p...

journal_title：International journal of colorectal disease

authors： Imai M,Kamimura K,Takahashi Y,Sato T,Isokawa O,Maruyama M,Kobayashi T,Hayashi K,Terai S

更新日期：2018-02-01 00:00:00