Near infrared technology in neuroscience: past, present and future.

Abstract:

OBJECTIVE:To review past, present and future applications of near-infrared spectroscopy (NIRS) in clinical neuroscience. METHODS:The literature and personal experience of the authors were critically reviewed in order to provide a balanced overview of the basic principles, clinical validation, previous experience and current use of NIRS in assessment of cerebral oxygenation in clinical neuroscience. RESULTS:Recent technological advancements in transcranial cerebral oximetry (TCCO) are opening up a new promising avenue in clinical neuroscience. With its non-invasive nature, high reliability and uniqueness of gathered data, NIRS represents a very special modality in the neuroscience intensive care unit, angiography suite and the operating room. The hurdles of using this technology in clinical practice are discussed in detail. In addition, we evaluate some known limitations of NIRS and current controversies around its use. Lastly, several commercially available cerebral oximeters are presented. CONCLUSION:Despite remarkable developments in the NIRS technology and proven reliability of the cerebral oxygenation monitoring approach, TCCO remains mostly an adjuvant tool for neuroscience applications. Newer NIRS technologies have become a source of quantitative information about brain oxygenation, cerebral blood volume and flow. However, the clinical significance of this new information in the context of clinical neuroscience will need to be determined and further validation studies will need to be performed.

journal_name

Neurol Res

journal_title

Neurological research

authors

Calderon-Arnulphi M,Alaraj A,Slavin KV

doi

10.1179/174313209X383286

subject

Has Abstract

pub_date

2009-07-01 00:00:00

pages

605-14

issue

6

eissn

0161-6412

issn

1743-1328

journal_volume

31

pub_type

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