Everyday functioning in mild cognitive impairment and its relationship with executive cognition.

abstract：OBJECTIVES:To identify subtypes of neuropsychiatric symptom (NPS) course among cognitively normal individuals and to assess the association between these subtypes and hazard of later mild cognitive impairment (MCI) or dementia diagnosis. METHODS:We modeled neuropsychiatric inventory questionnaire (NPI-Q) scores from 4...

journal_title：International journal of geriatric psychiatry

authors： Leoutsakos JS,Wise EA,Lyketsos CG,Smith GS

更新日期：2019-12-01 00:00:00

abstract：OBJECTIVE:To measure depressive symptomatology in a largely illiterate elderly population in India, using a new Hindi version of the Geriatric Depression Scale (GDS-H), and to examine its distribution and associations with age, gender, literacy, cognitive impairment and functional impairment. DESIGN:A Hindi version of...

journal_title：International journal of geriatric psychiatry

authors： Ganguli M,Dube S,Johnston JM,Pandav R,Chandra V,Dodge HH

更新日期：1999-10-01 00:00:00

abstract：OBJECTIVE:Meta-analyses of antidepressant drug treatment trials have found that increasing age is associated with a less favourable outcome. Because the prevalence of geriatric characteristics, like disability, medical co-morbidity, malnutrition, cognitive (dys)function and frailty increase with age and are associated ...

journal_title：International journal of geriatric psychiatry

authors： Benraad CE,Kamerman-Celie F,van Munster BC,Oude Voshaar RC,Spijker J,Olde Rikkert MG

更新日期：2016-09-01 00:00:00

abstract：BACKGROUND:The management of Behavioural and Psychological Symptoms of Dementia (BPSD) has been the subject of considerable debate over the last few years in view of the poor evidence base for pharmacological agents and concerns about their safety. OBJECTIVES:This study sought to obtain expert opinion on the managemen...

journal_title：International journal of geriatric psychiatry

authors： Bishara D,Taylor D,Howard RJ,Abdel-Tawab R

更新日期：2009-09-01 00:00:00

abstract：OBJECTIVE:This study examined the associations of personality characteristics with both subtypes and symptom dimensions of depression in older adults. METHODS:Three hundred and seventy-eight depressed older adults participated in the Netherlands Study of Depression in Older Persons. Personality characteristics were as...

journal_title：International journal of geriatric psychiatry

authors： Koorevaar AML,Hegeman JM,Lamers F,Dhondt ADF,van der Mast RC,Stek ML,Comijs HC

更新日期：2017-12-01 00:00:00

abstract：RATIONALE:Quetiapine was approved in Germany as an atypical antipsychotic for treatment of schizophrenia in 2000, followed by the approval as an antipsychotic for treatment of bipolar mania in 2003. The approval of quetiapine for treatment of bipolar depression is expected. We hypothesized that the psychogeriatric pres...

journal_title：International journal of geriatric psychiatry

authors： Hilwerling L,Juckel G,Schröder SG

更新日期：2007-05-01 00:00:00

abstract：OBJECTIVE:To elucidate the extent to which elderly people with cognitive impairment are able to answer questions about their quality of life.Design and setting308 elderly residents were interviewed within 2 weeks of admission to one of 30 residential or nursing homes in north-west England. MEASURES:The Mini-Mental Sta...

journal_title：International journal of geriatric psychiatry

authors： Mozley CG,Huxley P,Sutcliffe C,Bagley H,Burns A,Challis D,Cordingley L

更新日期：1999-09-01 00:00:00

abstract：OBJECTIVE:We investigated cognitive dysfunction in patients with Alzheimer's disease (AD) and amnestic mild cognitive impairment (aMCI) who present hemispheric asymmetries of cerebral metabolic rate of glucose (CMRglc) decrease on (18) F-fluorodeoxyglucose positron emission tomography. METHODS:Based on the hemispheric...

journal_title：International journal of geriatric psychiatry

authors： Murayama N,Ota K,Kasanuki K,Kondo D,Fujishiro H,Fukase Y,Tagaya H,Sato K,Iseki E

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Despite a consensus on the need to expand and improve mental health care for older people, evidence on models of service development is limited. OBJECTIVE:Referring to two case studies, this paper considers how evaluation of service innovations can inform policy and practice. CONCLUSIONS:Evaluation should ...

journal_title：International journal of geriatric psychiatry

authors： McCrae N,Banerjee S

更新日期：2011-06-01 00:00:00

abstract：:Reduced N-acetyl aspartate (NAA) and increased myo-inositol (MI) levels have been reported in patients with dementia of Alzheimer type (DAT) in comparison with controls. We wished to assess the validity of these findings and to evaluate possible correlations of metabolite proportions with cognitive dysfunction in DAT....

journal_title：International journal of geriatric psychiatry

authors： Heun R,Schlegel S,Graf-Morgenstern M,Tintera J,Gawehn J,Stoeter P

更新日期：1997-03-01 00:00:00

abstract：OBJECTIVE:Cross validation study of the MoCA for the detection of Alzheimer's disease (AD) and Mild Cognitive Impairment (MCI) in a community-based cohort residing in the Southeastern United States. METHODS:One hundred and eighteen English-speaking older adults, who underwent diagnostic evaluation as part of an on-goi...

journal_title：International journal of geriatric psychiatry

authors： Luis CA,Keegan AP,Mullan M

更新日期：2009-02-01 00:00:00

abstract：OBJECTIVE:Evidence in younger populations suggests quantitative but not categorical differences in cognitive impairments between schizophrenia and bipolar disorder. It is uncertain whether a similar distinction applies to patients in later life. METHODS:We compared the cognitive abilities of older, community-living sc...

journal_title：International journal of geriatric psychiatry

authors： Meesters PD,Schouws S,Stek M,de Haan L,Smit J,Eikelenboom P,Beekman A,Comijs H

更新日期：2013-01-01 00:00:00

abstract：OBJECTIVE:To determine the rate of psychiatric symptoms among elderly people with learning disabilities who have dementia. DESIGN:Survey. SETTING:The general community of a county in the UK. PARTICIPANTS:The whole population of people with learning disabilities who were 65 years or over. The total population was 143...

journal_title：International journal of geriatric psychiatry

authors： Cooper SA

更新日期：1997-06-01 00:00:00

abstract：:Alzheimer's disease (AD) affects millions of people worldwide and the number of AD cases will increase with increased life expectancy. Today there is no cure for this devastating and always lethal disease and therefore it is of great interest for patients, relatives and societies to find new drugs that can hinder the ...

journal_title：International journal of geriatric psychiatry

authors： Ankarcrona M,Winblad B

更新日期：2005-02-01 00:00:00

abstract：INTRODUCTION:Dementia Care Mapping (DCM) was originally developed as a clinical tool but has attracted interest as a potential observational measure of quality of life (QOL) and well-being of long-term care residents with dementia. DCM coding involves continuous observation over a 6-h period, with observers recording a...

journal_title：International journal of geriatric psychiatry

authors： Sloane PD,Brooker D,Cohen L,Douglass C,Edelman P,Fulton BR,Jarrott S,Kasayka R,Kuhn D,Preisser JS,Williams CS,Zimmerman S

更新日期：2007-06-01 00:00:00

abstract：OBJECTIVE:The aim of this study is to analyze modifiable factors related to agitation of nursing home residents with dementia. METHODS:Relationship of agitation with three modifiable factors (depression, psychosis, and pain) was explored using longitudinal Minimum Data Set (MDS) information from 2032 residents of Dutc...

journal_title：International journal of geriatric psychiatry

authors： Volicer L,Frijters DH,Van der Steen JT

更新日期：2012-07-01 00:00:00

abstract：OBJECTIVE:To evaluate the impact of cardiovascular disease (CVD) on mortality and readmission risk in patients with dementia. METHODS:Prospective hospital-based cohort of 59 194 patients with dementia admitted to hospital or visiting a day-clinic between 2000 and 2010. Patients were divided in those with and without a...

journal_title：International journal of geriatric psychiatry

authors： van de Vorst IE,Vaartjes I,Bots ML,Koek HL

更新日期：2019-03-01 00:00:00

abstract：OBJECTIVES:The objectives of this study are to explore the feasibility of a multicomponent intervention programme and to evaluate its impacts on behavioural and psychological symptoms of dementia (BPSD) and psychological health of caregivers. METHODS:Fifty-six community-dwelling people with dementia (PWD) and knee ost...

journal_title：International journal of geriatric psychiatry

authors： Law W,Kwok TCY

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND:It is unknown to what extent depression and cognitive dysfunction are related in subjects with dementia. A limitation of earlier studies is that only general measures of depression have been studied. METHODS:In a sample of 60 subjects with dementia according to DSM-III-R criteria depressive symptoms were di...

journal_title：International journal of geriatric psychiatry

authors： Janzing JG,Naarding P,Eling PA

更新日期：2005-05-01 00:00:00

abstract：OBJECTS:Identification of biomarkers for Alzheimer's disease (AD) is important for its early diagnosis and prevention and a key in advancing our understanding of its pathophysiology. The aim of this study was to determine whether systemic inflammatory interleukin-1ß (IL-1ß) and interleukin-6 (IL-6) as well as hypertens...

journal_title：International journal of geriatric psychiatry

authors： Honma T,Hatta K,Hitomi Y,Kambayashi Y,Hibino Y,Konoshita T,Nakamura H

更新日期：2013-03-01 00:00:00

abstract：OBJECTIVE:To review and summarise published data on medication errors in older people with mental health problems. METHODS:A systematic review was conducted to identify studies that investigated medication errors in older people with mental health problems. MEDLINE, EMBASE, PHARMLINE, COCHRANE COLLABORATION and PsycIN...

journal_title：International journal of geriatric psychiatry

authors： Maidment ID,Haw C,Stubbs J,Fox C,Katona C,Franklin BD

更新日期：2008-06-01 00:00:00

abstract：BACKGROUND:Dementia is a major public health problem. Increased attention is being paid to the quality of life (QOL) of people with this chronic disease. There have been no longitudinal studies of QOL change in dementia. METHOD:Longitudinal study of a cohort of 47 persons with dementia residing in a long-term care fac...

journal_title：International journal of geriatric psychiatry

authors： Lyketsos CG,Gonzales-Salvador T,Chin JJ,Baker A,Black B,Rabins P

更新日期：2003-04-01 00:00:00

abstract：OBJECTIVES:Impaired insight into illness is a prevalent feature of schizophrenia, which negatively influences treatment adherence and clinical outcomes. Little is known about the effects of aging on insight impairment. We aimed to review the available research literature on the effects of aging on insight into illness ...

journal_title：International journal of geriatric psychiatry

authors： Gerretsen P,Plitman E,Rajji TK,Graff-Guerrero A

更新日期：2014-11-01 00:00:00

abstract：OBJECTIVES:To investigate the effect of cobalamin/folate supplementation on cognitive function in elderly patients with dementia. METHOD:The cobalamin/folate status of the patients was evaluated by measuring plasma homocysteine, serum methylmalonic acid, serum cobalamin and blood folate. Thirty-three patients were stu...

journal_title：International journal of geriatric psychiatry

authors： Nilsson K,Gustafson L,Hultberg B

更新日期：2001-06-01 00:00:00

abstract：OBJECTIVE:To establish the factor structure, reliability and validity of a brief CESD scale among Community dwelling older adults in Singapore. METHOD:Data were derived from interviews conducted among 1,013 randomly selected non-institutionalized older adults aged 65 years and above in Singapore. First, Confirmatory F...

journal_title：International journal of geriatric psychiatry

authors： Lee AE,Chokkanathan S

更新日期：2008-06-01 00:00:00

abstract：OBJECTIVE:The aim of this study is to examine the hypotheses stating the importance of amyloid or of its oligomers in the pathogenesis of Alzheimer's disease (AD). METHODS:Published studies were examined. RESULTS:The importance of amyloid in the pathogenesis of AD is well established, yet accepting it as the main cau...

journal_title：International journal of geriatric psychiatry

authors： Fessel J

更新日期：2018-01-01 00:00:00

abstract：OBJECTIVE:To find a blood biomarker and disease-related peptides in Alzheimer's disease (AD), we comprehensively detected serum peptides. METHODS:Ion intensity of serum peptides from 62 AD patients and 82 control subjects was measured by mass spectrometry. RESULTS:A total of 157 peptides were detected from 30 AD pati...

journal_title：International journal of geriatric psychiatry

authors： Noguchi M,Sato T,Nagai K,Utagawa I,Suzuki I,Arito M,Iizuka N,Suematsu N,Okamoto K,Kato T,Yamaguchi N,Kurokawa MS

更新日期：2014-08-01 00:00:00

abstract：OBJECTIVES:To explore the extent of and factors associated with male residents who change wandering status post nursing home admission. DESIGN:Longitudinal design with secondary data analyses. Admissions over a 4-year period were examined using repeat assessments with the Minimum Data Set (MDS) to formulate a model un...

journal_title：International journal of geriatric psychiatry

authors： King-Kallimanis B,Schonfeld L,Molinari VA,Algase D,Brown LM,Kearns WD,Davis DM,Werner DH,Beattie ER,Nelson AL

更新日期：2010-02-01 00:00:00

abstract：OBJECTIVE:To examine the utility of a brief, metacognition questionnaire by examining its association with objective cognitive testing and informant ratings. We hypothesized that the association between self-ratings of change and both outcomes would be greater among individuals without dementia than among those with de...

journal_title：International journal of geriatric psychiatry

authors： Buckley T,Norton MC,Deberard MS,Welsh-Bohmer KA,Tschanz JT

更新日期：2010-07-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to examine whether delirium has specific clinical subtypes. METHOD:One hundred and eighty-three elderly subjects meeting DSM-IIIR criteria for delirium were evaluated using a 19-item symptom check-list assessing different dimensions of delirium symptomatology. Exploratory factor ana...

journal_title：International journal of geriatric psychiatry

authors： Camus V,Burtin B,Simeone I,Schwed P,Gonthier R,Dubos G

更新日期：2000-04-01 00:00:00