Abstract:
OBJECTIVE:To assess psychological and social functioning and health related quality of life and its early determinants in children born with congenital diaphragmatic hernia (CDH). DESIGN:Cross-sectional follow-up study. SETTING:Outpatient clinic of a tertiary care hospital. PARTICIPANTS:33 CDH survivors aged 6-16 years. MAIN EXPOSURE:Patients who developed CDH associated respiratory distress within 24 h after birth. MAIN OUTCOME MEASURE:Psychological and social functioning assessed with the Wechsler Intelligence Scale for Children (WISC-R), Bourdon-Vos test, Beery Developmental Test of Visual Motor Integration, Child Behavior Checklist (CBCL) and Teacher Report Form (TRF), and health related quality of life assessed with the Child Health Questionnaire (CHQ) and Health Utilities Index (HUI). RESULTS:Normal mean (SD) total IQ (100.0 (13.2)) and normal visual-motor integration, but significantly lower results for sustained attention (Bourdon-Vos test, 38.8 (11.2) points) were found. Learning difficulties were reported by 30% of parents. Eight children had scores in the clinical range on the CBCL and/or TRF, indicating clinically significant behavioural problems. Except for the CHQ scale General Health, health status was not different from the reference population. No significant correlations between test results and severity of CDH were found, except for an association of general health and physical functioning with length of hospital stay. CONCLUSION:CDH patients are at risk for subtle cognitive and behavioural problems, probably not related to CDH severity. Perception of general health is reduced compared to the reference population, indicating that CDH survivors and their parents believe their health is poor and likely to get worse.
journal_name
Arch Dis Childjournal_title
Archives of disease in childhoodauthors
Peetsold MG,Huisman J,Hofman VE,Heij HA,Raat H,Gemke RJdoi
10.1136/adc.2008.156158subject
Has Abstractpub_date
2009-11-01 00:00:00pages
834-40issue
11eissn
0003-9888issn
1468-2044pii
adc.2008.156158journal_volume
94pub_type
杂志文章abstract::Fever is a common symptom of childhood illness, and much time and effort is spent in the pursuit of reducing high temperature. Although antipyretic drugs are the main form of treatment, this report considers the part that physical treatments might play in reducing the temperature of febrile children. Such treatments i...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.82.3.238
更新日期:2000-03-01 00:00:00
abstract::Nocturnal growth hormone secretion over a 12 hour period was assessed at 20 minute intervals in 25 prepubertal subjects with Turner's syndrome and 11 normal prepubertal girls of short stature to try and elucidate the relationship between body weight and endogenous secretion of growth hormone in Turner's syndrome. Ther...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.66.10.1184
更新日期:1991-10-01 00:00:00
abstract:BACKGROUND:In 1999, invasive meningococcal disease was hyperendemic in Ireland at 14.75/100 000 population, with 60% group B and 30% group C diseases. National sepsis guidelines and meningococcal C vaccines were introduced in 2000. Despite a spontaneous decline in group B infection, invasive meningococcal disease remai...
journal_title:Archives of disease in childhood
pub_type: 杂志文章,多中心研究
doi:10.1136/archdischild-2015-310215
更新日期:2016-12-01 00:00:00
abstract::A questionnaire relating to smoking habits, respiratory symptoms, and health attitude was administered to schoolchildren aged between 11 and 17 throughout a defined geographical area in both 1975 and 1979, with a valid response from 10498 and 12002 young people respectively. Each cohort was almost entirely different. ...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.57.5.352
更新日期:1982-05-01 00:00:00
abstract::The past year has produced several new clinical guidelines germane to paediatric dermatology, as well as important work related to rheumatologic overlap disorders, psoriasis comorbidities, pigmented lesions and quality of life impact. This review highlights common diagnoses and treatments useful for the practicing pae...
journal_title:Archives of disease in childhood
pub_type: 杂志文章,评审
doi:10.1136/archdischild-2013-304398
更新日期:2014-10-01 00:00:00
abstract:AIM:To assess the value and safety of fasts for investigating hypoglycaemia or suspected metabolic disease. STUDY DESIGN:Review of all diagnostic fasts performed over a 2.5 year period. SETTING:The neonatal intensive care unit and programmed investigation unit at a tertiary referral centre for endocrinology and metab...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.75.2.115
更新日期:1996-08-01 00:00:00
abstract:OBJECTIVES:To assess the efficacy and safety of polyethylene glycol 3350 plus electrolytes (PEG+E) for the treatment of chronic constipation in children. DESIGN:Randomised, double blind, placebo controlled crossover trial, with two 2-week treatment periods separated by a 2-week placebo washout. SETTING:Six UK paediat...
journal_title:Archives of disease in childhood
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1136/adc.2006.115493
更新日期:2007-11-01 00:00:00
abstract:BACKGROUND:The number of children admitted to hospital is increasing year on year, with very short-stay admissions doubling in the last decade. Childhood head injury accounts for half a million emergency department attendances in the UK every year. The National Institute for Health and Care Excellence (NICE) has issued...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/archdischild-2015-308615
更新日期:2015-12-01 00:00:00
abstract:AIM:Assessment of the efficacy of vitamin D replenishment and maintenance doses required to attain optimal levels in boys with Duchenne muscular dystrophy (DMD). METHOD:25(OH)-vitamin D levels and concurrent vitamin D dosage were collected from retrospective case-note review of boys with DMD at the Dubowitz Neuromuscu...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/archdischild-2015-308825
更新日期:2016-10-01 00:00:00
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journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.77.5.396
更新日期:1997-11-01 00:00:00
abstract:OBJECTIVES:To estimate the incidence of cystic-fibrosis-related diabetes (CFRD) in youth from New South Wales (NSW) and the Australian Capital Territory (ACT), Australia and to examine demographic/clinical features at diagnosis. METHODS:Incident cases of CFRD in young people aged ≤ 18 years diagnosed during 2000 to 20...
journal_title:Archives of disease in childhood
pub_type: 杂志文章,多中心研究
doi:10.1136/adc.2010.208652
更新日期:2011-09-01 00:00:00
abstract::A 20-year-old woman with untreated homocystinuria was examined when she was 18 weeks' pregnant. Amniocentesis was performed and raised levels of homocystine and methionine were present in the amniotic fluid. Assay of cystathionine synthetase activity in cultured amniotic fluid cells showed the carrier state for homocy...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.55.9.721
更新日期:1980-09-01 00:00:00
abstract:AIM:Ketamine is used for post-operative analgesia. There has been recent disruption in it's supply. It is usually prescribed by patient's weight (3 mg/kg in 50 ml 0.9% saline) at a rate of 1-5 ml/hr (1-5 microgram/kg/minute). To conserve ketamine supplies our policy was changed to a concentrated "standardised" concentr...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/archdischild-2016-311535.12
更新日期:2016-09-01 00:00:00
abstract::In a family in which the father carried a balanced translocation between chromosomes 15 and 22 two of his children had Prader-Willi syndrome and an unbalanced chromosome complement, having lost the proximal bands from the long arm of chromosome 15. His four other surviving children were normal but carried a balanced t...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.62.8.841
更新日期:1987-08-01 00:00:00
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journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.2004.057091
更新日期:2005-07-01 00:00:00
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journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/archdischild-2016-311535.49
更新日期:2016-09-01 00:00:00
abstract::No consistent differences were found in mean heights and weights of 170 schoolchildren aged 6--12 years with the sickle cell trait and 1247 schoolchildren with normal haemoglobin living in Dominica and Jamaica. ...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.53.7.596
更新日期:1978-07-01 00:00:00
abstract::Albuminuria was studied in 40 diabetic children before and after a standardised exercise test, and also in 21 normal children; the results are expressed as geometric mean (95% range) of urine albumin:urine creatinine ratio (mg/mg). There was no significant difference between the mean resting albumin:creatinine ratio i...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.60.4.305
更新日期:1985-04-01 00:00:00
abstract::The partial androgen insensitivity syndrome occurs in 46,XY subjects with phenotypes ranging from perineoscrotal hypospadias with cryptorchidism and micropenis (mild undervirilisation) to clitoromegaly and partial labial fusion (marked undervirilisation). Within an affected family, wide variation in the degree of geni...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.68.4.453
更新日期:1993-04-01 00:00:00
abstract::An 11 year old boy presented with severe acute hereditary coproporphyria. Despite supportive measures his condition deteriorated after admission. Haem arginate, started two days after presentation, produced appreciable inhibition of porphyrin precursor overproduction and clinical improvement. ...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.66.6.730
更新日期:1991-06-01 00:00:00
abstract::Transient hyperphosphatasaemia is usually a chance finding arising from the use of biochemical screening profiles. Clinical correlates in cases so far described have been non-specific. ...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.59.10.996
更新日期:1984-10-01 00:00:00
abstract::Samples of saliva and nasal secretions were collected sequentially from 15 breast fed and 15 bottle fed infants on five occasions between 6 days and 9 months of age. Total immunoglobulin concentrations of G, M, and A classes, and class specific antibodies to tetanus toxoid and a pool of commensal strains of Escherichi...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.61.3.263
更新日期:1986-03-01 00:00:00
abstract:OBJECTIVE:To assess height and body mass index standard deviation scores up to 20 years after treatment for acute lymphoblastic leukaemia (ALL). SUBJECTS AND METHODS:Height and body mass index standard deviation scores were measured in 33 patients (14 boys and 19 girls) with childhood ALL at diagnosis, after the end o...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.79.2.161
更新日期:1998-08-01 00:00:00
abstract:OBJECTIVE:To assess the benefit of nebulised amiloride added to the standard inpatient treatment of a respiratory exacerbation in cystic fibrosis. DESIGN:Prospective, randomised, double blind, placebo controlled trial. SUBJECTS:27 cystic fibrosis patients (mean age 12.8 years). SETTING:Two hospitals in Leeds, UK. R...
journal_title:Archives of disease in childhood
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1136/adc.73.5.427
更新日期:1995-11-01 00:00:00
abstract::In 1973 a survey was conducted among 12 year old children living in a defined area of South Wales. In 1988 the survey was repeated in the same area, again among 12 year old children. Questionnaires were completed for all 965 children in the population sample; peak expiratory flow rates were performed on them all, and ...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.64.10.1452
更新日期:1989-10-01 00:00:00
abstract:OBJECTIVE:To describe the recent trends in demographic, clinical and microbiological characteristics and outcome of treatment in paediatric cases of tuberculosis. DESIGN:National surveillance study. SETTING:England and Wales. PATIENTS:All children under the age of 16 years reported with tuberculosis to the national ...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.2008.139543
更新日期:2008-12-01 00:00:00
abstract:OBJECTIVE:To examine the value of neurodevelopmental examination, fragile X testing, iron studies, and other screening procedures in children with mild to moderate learning difficulties. DESIGN:A cross sectional case-control study. SUBJECTS:A 34% random sample (n = 130) of children with mild to moderate learning diff...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.76.3.264
更新日期:1997-03-01 00:00:00
abstract:OBJECTIVES:To determine whether there is evidence of immunological responses in infants with respiratory syncytial virus (RSV) bronchiolitis by measuring inflammatory mediators in peripheral blood and, if found, whether these related to the severity of illness. PATIENTS AND METHODS:Blood was taken from 94 children wit...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.76.3.210
更新日期:1997-03-01 00:00:00
abstract::Serial exercise tests were carried out by 12 children with asthma on two study days. After a control exercise test either nedocromil sodium 4 mg or placebo were given double blind by metered dose inhaler. Highly significant inhibition of exercise induced asthma occurred after nedocromil, lasting for over two hours. ...
journal_title:Archives of disease in childhood
pub_type: 临床试验,杂志文章
doi:10.1136/adc.62.4.412
更新日期:1987-04-01 00:00:00
abstract::Thirty jaundiced neonates with diarrhoea who were being treated with phototherapy and 30 matched control infants were studied to try and find out the cause of the diarrhoea. Faecal osmolality and electrolyte concentrations were measured, which gave clear evidence that the diarrhoea arose from intestinal secretion. Rec...
journal_title:Archives of disease in childhood
pub_type: 杂志文章
doi:10.1136/adc.64.8.1161
更新日期:1989-08-01 00:00:00