Serum leptin concentrations in relation to pubertal development.

abstract：OBJECTIVE:To ascertain mortality from 1 to 18 years, and predictors of mortality. DESIGN:Long-term follow-up of population cohort born 1989-1992. SETTING:Births in South East Thames Region. PATIENTS:346 children with bilateral cerebral palsy (CP). INTERVENTIONS:Not applicable. MAIN OUTCOME MEASURES:Mortality; pred...

journal_title：Archives of disease in childhood

authors： Baird G,Allen E,Scrutton D,Knight A,McNee A,Will E,Elbourne D

更新日期：2011-11-01 00:00:00

abstract：:The allergic response is distinct from other immune reactions in its reliance on IgE, its high affinity receptor, Fc epsilon RI, and the primary effector cell--the tissue mast cell. Positive skin tests or raised concentrations of specific immunoglobulin E (IgE) in the serum define IgE sensitisation or "atopy". IgE par...

journal_title：Archives of disease in childhood

authors： Milgrom H

更新日期：2003-01-01 00:00:00

abstract：:The lactulose/L-rhamnose urinary excretion ratio during continued infusion of milks containing both sugars was used as an index of the permeability of the neonatal bowel to large and small molecules. Healthy infants of gestational age 31-36 weeks proved to have a period of enhanced permeability to lactulose during the...

journal_title：Archives of disease in childhood

authors： Beach RC,Menzies IS,Clayden GS,Scopes JW

更新日期：1982-02-01 00:00:00

abstract：:The relationship of vesicoureteric reflex (VUR) and renal scarring was studied in 94 children (188 kidneys) with proved urinary tract infection in a district general hospital. There were 61 girls and 33 boys, with nine girls and 17 boys aged less than 1 year, 31 girls and nine boys aged between 1 and 5 years, the rema...

journal_title：Archives of disease in childhood

authors： Gleeson FV,Gordon I

更新日期：1991-11-01 00:00:00

abstract：OBJECTIVE:This study aimed to determine the glycaemic profile of patients with cystic fibrosis using a continuous glucose monitoring system (CGMS), and to evaluate the associations of glycaemic abnormalities with sex, age, pubertal stage, CFTR gene mutations, nutritional status, lung function, oral glucose tolerance te...

journal_title：Archives of disease in childhood

authors： Zorrón Mei Hsia Pu M,Gonçalves AC,Minnicucci WJ,Morcillo AM,Ribeiro JD,Ribeiro AF

更新日期：2018-06-01 00:00:00

abstract：:The recent epidemic of childhood obesity(1) has raised concern because of the possible clinical and public health consequences.(2,)(3) However, there remains a widespread perception among health professionals that childhood obesity is a largely cosmetic problem, with minor clinical effects. No systematic review has ye...

journal_title：Archives of disease in childhood

authors： Reilly JJ,Methven E,McDowell ZC,Hacking B,Alexander D,Stewart L,Kelnar CJ

更新日期：2003-09-01 00:00:00

abstract：BACKGROUND:Sodium phenylbutyrate (NaPB) is used as a treatment for urea cycle disorders (UCD). However, the available, licensed granule form has an extremely bad taste, which can compromise compliance and metabolic control. OBJECTIVES:A new, taste-masked, coated-granule formulation (Luc 01) under development was chara...

journal_title：Archives of disease in childhood

authors： Guffon N,Kibleur Y,Copalu W,Tissen C,Breitkreutz J

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND:There are few data on the optimal micronutrient composition of paediatric enteral feeds. The recent European Directive on Foods for Special Medical Purposes (1999/21/EC) did not distinguish between the composition of adult and paediatric feeds. AIMS:To evaluate, in an open, observational study, the long ter...

journal_title：Archives of disease in childhood

authors： Johnson TE,Janes SJ,MacDonald A,Elia M,Booth IW

更新日期：2002-06-01 00:00:00

abstract：:The proportion of babies colonised with gentamicin resistant Gram negative organisms in a nursery over a 30 month period did not correlate with the quantity or duration of aminoglycosides used, but it did correlate with two indicators of workload: the number of baby days and a score based on the level of nursing care ...

journal_title：Archives of disease in childhood

authors： Isaacs D,Catterson J,Hope PL,Moxon ER,Wilkinson AR

更新日期：1988-05-01 00:00:00

abstract：:Four Asian babies were investigated because they failed to thrive. In all four cases the failure to thrive was a result of the mother's social isolation and inability to communicate, and to the father's refusal to accept that there was a problem in the family. ...

journal_title：Archives of disease in childhood

authors： Fenton TR,Bhat R,Davies A,West R

更新日期：1989-03-01 00:00:00

abstract：OBJECTIVES:To describe the clinical presentation and sequelae, including salt-wasting crises of newly-diagnosed congenital adrenal hyperplasia (CAH) in children aged over 1 year in a contemporary population without screening. To appraise the potential benefit of newborn screening for late-presenting CAH. DESIGN:Active...

journal_title：Archives of disease in childhood

authors： Knowles RL,Khalid JM,Oerton JM,Hindmarsh PC,Kelnar CJ,Dezateux C

更新日期：2014-01-01 00:00:00

abstract：:Lipofuscin develops in cells when peroxidation damage occurs. Its development in the liver of patients receiving prolonged parenteral nutrition suggests that peroxidation damage by free radicals has occurred. Deficiencies in antioxidants such as vitamin E may be an important contributing factor. ...

journal_title：Archives of disease in childhood

authors： Berger HM,Den Ouden AL,Calame JJ

更新日期：1985-08-01 00:00:00

abstract：:Two siblings were born with congenital heart block, and one suffered from severe hydrops fetalis, although maintaining a higher heart rate than the other. The association of hydrops fetalis with disorders of cardiac rhythm is unlikely to be simply a manifestation of congestive cardiac failure in the fetus. ...

journal_title：Archives of disease in childhood

authors： Cooke RW,Mettau JW,Van Cappelle AW,de Villeneuve VH

更新日期：1980-06-01 00:00:00

abstract：BACKGROUND:Recent research in febrile neutropaenia (FN) has focused on reducing the intensity of treatment for those thought to be at low risk of significant morbidity or mortality. This has not led to a reduced burden of treatment for either families or healthcare systems. An alternative approach is to discharge all p...

journal_title：Archives of disease in childhood

authors： Seneviratne N,Yeomanson D,Phillips R

更新日期：2020-09-01 00:00:00

abstract：:The reliability and validity of the North American paediatric appropriateness evaluation protocol (PAEP) for use in paediatric practice in Britain was tested. The protocol was applied to 418 case records of consecutive emergency admissions to three Yorkshire district general hospitals. The PAEP ratings were then compa...

journal_title：Archives of disease in childhood

authors： Werneke U,Smith H,Smith IJ,Taylor J,MacFaul R

更新日期：1997-10-01 00:00:00

abstract：AIMS:To pilot a novel approach to providing pharmaceutical care to paediatric inpatients using structured referral and assessment tools. Using standardised referral criteria to ensure patients are assessed by appropriately skilled pharmacists. METHOD:Three wards of varying acuity and specialism were selected in a tert...

journal_title：Archives of disease in childhood

authors： Mott A,Kafka S,Sutherland A

更新日期：2016-09-01 00:00:00

abstract：PURPOSE:To prospectively examine relations between maternal DSM-IV-TR anxiety and depressive disorders and excessive infant crying. METHODS:Based on the prospective longitudinal Maternal Anxiety in Relation to Infant Development Study, n=306 expectant mothers were enrolled during early pregnancy and repeatedly intervi...

journal_title：Archives of disease in childhood

authors： Petzoldt J,Wittchen HU,Wittich J,Einsle F,Höfler M,Martini J

更新日期：2014-09-01 00:00:00

abstract：BACKGROUND:Several studies have shown an increased incidence of neurodevelopmental impairment in very preterm survivors at school age compared with controls. AIM:To compare findings in the same cohort at 8 years and 15 years. METHODS:A total of 151 of the 224 eligible infants born before 33 weeks of gestation from 19...

journal_title：Archives of disease in childhood

authors： O'Brien F,Roth S,Stewart A,Rifkin L,Rushe T,Wyatt J

更新日期：2004-03-01 00:00:00

abstract：OBJECTIVES:Children's exposure to racism via caregiver experience (vicarious racism) is associated with poorer health and development. However, the relationship with child healthcare utilisation is unknown. We aimed to investigate (1) the prevalence of vicarious racism by child ethnicity; (2) the association between ca...

journal_title：Archives of disease in childhood

authors： Paine SJ,Harris R,Stanley J,Cormack D

更新日期：2018-09-01 00:00:00

abstract：:A special conditions register (SCR) linked to the child health system's register of all children has been in use in West Sussex since 1977. This paper describes the aims, organisation, and use of the SCR and gives examples of the aggregated data that may be obtained. Of the 155,000 children aged 0-17 resident in West ...

journal_title：Archives of disease in childhood

authors： Woodroffe C,Abra A

更新日期：1991-08-01 00:00:00

abstract：OBJECTIVE:There is a body of published research on the effectiveness of home visiting for the prevention of child maltreatment, but little in the peer reviewed literature on cost-effectiveness or value to society. The authors sought to determine the cost-effectiveness of alternative home visiting programmes to inform p...

journal_title：Archives of disease in childhood

authors： Dalziel K,Segal L

更新日期：2012-09-01 00:00:00

abstract：:Lung function tests were carried out in the first 6 hours of life on 26 babies born by vaginal delivery and 10 born by caesarean section. The babies born by caesarean section had a mean thoracic gas volume of only 19.7 ml/kg body weight compared with 32.7 ml/kg for the babies born vaginally. We conclude that this is o...

journal_title：Archives of disease in childhood

authors： Milner AD,Saunders RA,Hopkin IE

更新日期：1978-07-01 00:00:00

abstract：BACKGROUND:In recent years photopheresis, an extracorporeal form of photochemotherapy using psoralen and ultraviolet A irradiation of leucocytes, has been claimed to be an effective form of immunomodulation. AIM:To evaluate its effect in type 1 diabetes we performed a double blind, controlled study using placebo table...

journal_title：Archives of disease in childhood

authors： Ludvigsson J,Samuelsson U,Ernerudh J,Johansson C,Stenhammar L,Berlin G

更新日期：2001-08-01 00:00:00

abstract：BACKGROUND:Acute respiratory infections (ARI) cause 3 million deaths in children worldwide each year. Most of these deaths occur from pneumonia in developing countries, and hypoxaemia is the most common fatal complication. Simple and adaptable indications for oxygen therapy are important in the management of ARI. The c...

journal_title：Archives of disease in childhood

authors： Subhi R,Smith K,Duke T

更新日期：2009-01-01 00:00:00

abstract：OBJECTIVES:To determine long-term seroprotection after serogroup C meningococcal (MenC) vaccination at the age of 9-12 years, with or without booster vaccination at the age of 13-15 years. DESIGN:Observational cohort study; follow-on from randomised study. SETTING:Participants were recruited from English secondary sc...

journal_title：Archives of disease in childhood

authors： de Whalley PC,Snape MD,Plested E,Thompson B,Nuthall E,Omar O,Borrow R,Pollard AJ

更新日期：2013-09-01 00:00:00

abstract：:The partial androgen insensitivity syndrome occurs in 46,XY subjects with phenotypes ranging from perineoscrotal hypospadias with cryptorchidism and micropenis (mild undervirilisation) to clitoromegaly and partial labial fusion (marked undervirilisation). Within an affected family, wide variation in the degree of geni...

journal_title：Archives of disease in childhood

authors： Batch JA,Davies HR,Evans BA,Hughes IA,Patterson MN

更新日期：1993-04-01 00:00:00

abstract：:When isolated from the female genital tract, diphtheroids are usually regarded as commensal organisms. Corynebacterium kutscheri however is a pathogen in laboratory rodents. We report a case in which C. kutscheri was isolated as a pure culture from the umbilical cord and from other surface sites in an infant. Histolog...

journal_title：Archives of disease in childhood

authors： Fitter WF,de Sa DJ,Richardson H

更新日期：1979-09-01 00:00:00

abstract：:Copper deficiency is reported in an infant of very low birthweight. It was characterised by extensive bone changes, severe neutropenia, and hypocupraemia. These manifestations could have been missed but for an intercurrent pneumonia which led to an x-ray of the chest. ...

journal_title：Archives of disease in childhood

authors： Yuen P,Lin HJ,Hutchinson JH

更新日期：1979-07-01 00:00:00

abstract：OBJECTIVE:To examine the efficacy and safety of torasemide in children with chronic heart failure (HF). METHODS:102 children with chronic HF who had received oral torasemide were analysed. Of these, 62 (de novo group) were newly diagnosed as having HF and were given torasemide as a diuretic. The remaining 40 (replacem...

journal_title：Archives of disease in childhood

authors： Senzaki H,Kamiyama M,Masutani S,Ishido H,Taketazu M,Kobayashi T,Katogi T,Kyo S

更新日期：2008-09-01 00:00:00

abstract：:Samples of saliva (4 in 24 hours), collected at monthly intervals for the first 6 months of life in 8 term infants by their mothers, were analysed for cortisol by radioimmunoassay. Values in the first month were more variable, daily mean values were greater, and amplitudes of variation were greater than in subsequent ...

journal_title：Archives of disease in childhood

authors： Price DA,Close GC,Fielding BA

更新日期：1983-06-01 00:00:00