The neurodevelopmental progress of infants less than 33 weeks into adolescence.

abstract：OBJECTIVE:To define better the adult phenotype and natural history of Noonan syndrome. DESIGN:A prospective observational study of a large cohort. RESULTS:Data are presented for 112 individuals with Noonan syndrome (mean age 25.3 (range 12-71) years), who were followed up for a mean of 12.02 years. Mutations in PTPN1...

journal_title：Archives of disease in childhood

authors： Shaw AC,Kalidas K,Crosby AH,Jeffery S,Patton MA

更新日期：2007-02-01 00:00:00

abstract：OBJECTIVES:To assess uptake of community-based capillary thyroid stimulating hormone (TSH) screening in Scotland and determine the optimal frequency of screening, the justification for preschool screening and strategies for treatment. METHODS:Subjects with Down's syndrome aged 1-19 years underwent capillary TSH measur...

journal_title：Archives of disease in childhood

authors： McGowan S,Jones J,Brown A,Reynolds L,Leyland K,Charleton P,Rahim M,Mansor M,Ritha S,Donaldson M,Scottish Down Syndrome Thyroid Screening Group.

更新日期：2011-12-01 00:00:00

abstract：OBJECTIVE:There is a body of published research on the effectiveness of home visiting for the prevention of child maltreatment, but little in the peer reviewed literature on cost-effectiveness or value to society. The authors sought to determine the cost-effectiveness of alternative home visiting programmes to inform p...

journal_title：Archives of disease in childhood

authors： Dalziel K,Segal L

更新日期：2012-09-01 00:00:00

abstract：OBJECTIVE:To study the effect of modified polyunsaturated fatty acid (PUFA) profiles of complementary food on long-chain (LC) PUFA composition in healthy infants. DESIGN:Double blinded, randomised, controlled intervention trial. SETTING:Dortmund, Germany. PATIENTS:Free-living sample of healthy term infants. METHODS...

journal_title：Archives of disease in childhood

authors： Schwartz J,Dube K,Sichert-Hellert W,Kannenberg F,Kunz C,Kalhoff H,Kersting M

更新日期：2009-11-01 00:00:00

abstract：OBJECTIVE:Search for evidence supporting target age, level of intervention and target values for low-density lipoprotein (LDL) cholesterol levels in children with familial hypercholesterolemia. DESIGN:Systematic review and meta-analysis. PubMed, Medline, CINAHL and Cochrane Reviews databases from 1966 to 2007 were sea...

journal_title：Archives of disease in childhood

authors： Lebenthal Y,Horvath A,Dziechciarz P,Szajewska H,Shamir R

更新日期：2010-09-01 00:00:00

abstract：:We studied 91 offspring of ABO incompatible preganacies and 30 controls resulting from O--O pregnancies to test whether cord bilirubin levels could be used to predict the severity of hyperbilirubinaemia in ABO incompatibility. Blood group, direct Coombs's test, and serum bilirubin estimations were carried out on cord ...

journal_title：Archives of disease in childhood

authors： Risemberg HM,Mazzi E,MacDonald MG,Peralta M,Heldrich F

更新日期：1977-03-01 00:00:00

abstract：:Members of four generations of a family had a defect of serum opsonization for yeast phagocytosis consistent with dominant inheritance. 2 were healthy, one had chronic osteomyelitis, and the fourth developed a fatal illness in infancy characterized by exfoliative dermatitis, diarrhoea, multiple bacterial infections, a...

journal_title：Archives of disease in childhood

authors： Scott H,Moynahan EJ,Risdon RA,Harvey BA,Soothill JF

更新日期：1975-04-01 00:00:00

abstract：:A boy with the dysmorphic features of Noonan's syndrome and pulmonary valve stenosis who had evidence of hypoparathyroidism and abnormal T lymphocyte numbers in the neonatal period is reported. He had a normal karyotype but molecular analysis revealed a submicroscopic deletion within chromosome 22q11, the region delet...

journal_title：Archives of disease in childhood

authors： Wilson DI,Britton SB,McKeown C,Kelly D,Cross IE,Strobel S,Scambler PJ

更新日期：1993-02-01 00:00:00

abstract：:Primary ciliary dyskinesia was shown in a 12 year old boy with bronchiectasis who had developed hydrocephalus in the neonatal period. The possible relevance of his ciliary abnormality is discussed. ...

journal_title：Archives of disease in childhood

authors： Greenstone MA,Jones RW,Dewar A,Neville BG,Cole PJ

更新日期：1984-05-01 00:00:00

abstract：AIMS:To determine the prevalence of petechial spots in well babies. METHODS:A total of 116 babies under the age of 12 months were fully examined at child health surveillance clinics. The number and site of petechiae were recorded together with details of possible causes. RESULTS:A total of 27.6% of babies had one or ...

journal_title：Archives of disease in childhood

authors： Downes AJ,Crossland DS,Mellon AF

更新日期：2002-04-01 00:00:00

abstract：:In a family in which the father carried a balanced translocation between chromosomes 15 and 22 two of his children had Prader-Willi syndrome and an unbalanced chromosome complement, having lost the proximal bands from the long arm of chromosome 15. His four other surviving children were normal but carried a balanced t...

journal_title：Archives of disease in childhood

authors： Fernandez F,Berry C,Mutton D

更新日期：1987-08-01 00:00:00

abstract：OBJECTIVE:To study the clinical characteristics and predictors of mortality from snake bite envenomation in children. DESIGN:Prospective observational study with a one-group cohort design. SETTING:Paediatric intensive care unit of a tertiary care hospital in South India. SUBJECTS:The study cohort consisted of 145 ch...

journal_title：Archives of disease in childhood

authors： Jayakrishnan MP,Geeta MG,Krishnakumar P,Rajesh TV,George B

更新日期：2017-05-01 00:00:00

abstract：:During June and July 1977 5 junior boys in a boarding school for 800 pupils became ill with a mild infection caused by Coxsackie B1. The school had been taking part in a vaccine trial, and paired blood samples had been taken from new entrants in October 1976 and October 1977. 18% of the boys susceptible to the infecti...

journal_title：Archives of disease in childhood

authors： Hoskins TW,Davies JR,Smith AJ,Collingham K,Chamberlain RN

更新日期：1979-04-01 00:00:00

abstract：:Maternal transmission of hepatitis B virus infection in relation to the hepatitis B e antigen/antibody system and serum hepatitis B virus-DNA were evaluated. Results indicate that hepatitis B virus-DNA analysis can identify hepatitis B serum antigen positive mothers who may transmit infection to their offspring. ...

journal_title：Archives of disease in childhood

authors： De Virgiliis S,Frau F,Sanna G,Turco MP,Figus AL,Cornacchia G,Cao A

更新日期：1985-01-01 00:00:00

abstract：AIMS:To describe the clinical features, diagnosis and management of children with tuberculosis in the United Kingdom and Republic of Ireland. METHODS:Cases of culture-confirmed and clinically diagnosed tuberculosis were reported to the British Paediatric Surveillance Unit from December 2003 to January 2005. RESULTS:3...

journal_title：Archives of disease in childhood

authors： Teo SS,Riordan A,Alfaham M,Clark J,Evans MR,Sharland M,Novelli V,Watson JM,Sonnenberg P,Hayward A,Moore-Gillon J,Shingadia D,British Paediatric Surveillance Unit Childhood Tuberculosis Study Group.

更新日期：2009-04-01 00:00:00

abstract：:The neurodevelopmental state of 41 children with congenital cytomegalovirus infection and their controls was assessed at 2 years using the Griffiths scale. The scores achieved by children with congenital cytomegalovirus but with no associated neurological abnormality (asymptomatic) were similar to those of the control...

journal_title：Archives of disease in childhood

authors： Pearl KN,Preece PM,Ades A,Peckham CS

更新日期：1986-04-01 00:00:00

abstract：OBJECTIVE:To review the work of one tertiary paediatric palliative care service in facilitating planned withdrawal of ventilatory support outside the intensive care setting, with the purpose of developing local guidance for practice. METHODS:Retrospective 10-year (2003-2012) case note review of intensive care patients...

journal_title：Archives of disease in childhood

authors： Laddie J,Craig F,Brierley J,Kelly P,Bluebond-Langner M

更新日期：2014-09-01 00:00:00

abstract：:Safe and effective paediatric pharmacotherapy requires careful evaluation of the type of drug substance, the necessary dose and the age-appropriateness of the formulation. Generally, the younger the child, the more the attention that is required. For decades, there has been a general lack of (authorised) formulations ...

journal_title：Archives of disease in childhood

authors： van Riet-Nales DA,Schobben AF,Vromans H,Egberts TC,Rademaker CM

更新日期：2016-07-01 00:00:00

abstract：:Two neonates with acute infantile cerebral Gaucher's disease had prominent collodion skin. Ichthyosis has been described in some cases of metabolic lipid disorders, however, this is the first report of the association of lamellar desquamation of the newborn (collodion baby) with Gaucher's disease. ...

journal_title：Archives of disease in childhood

authors： Lui K,Commens C,Choong R,Jaworski R

更新日期：1988-07-01 00:00:00

abstract：OBJECTIVE:To investigate possible renal toxicity of long-term gentamicin inhalation in patients with cystic fibrosis. METHODS:Urinary N-acetyl-beta-D-glucosaminidase (NAG) activity was measured during routine respiratory clinic visits. Outpatient records were reviewed for data on long-term gentamicin inhalation, and p...

journal_title：Archives of disease in childhood

authors： Ring E,Eber E,Erwa W,Zach MS

更新日期：1998-06-01 00:00:00

abstract：:The term Ehlers-Danlos syndrome (EDS) encompasses a group of inherited connective tissue disorders. The manifestations of EDS can be seen in skin, joints, blood vessels and internal organs and vary from mild to severe and life threatening. Each subtype is a separate and different condition. The genetic basis of many s...

journal_title：Archives of disease in childhood

authors： Sobey G

更新日期：2015-01-01 00:00:00

abstract：:The output of the drug and the particle size produced by various nebulisers were assessed, and sensible nebulisation times for sodium cromoglycate calculated. Three of the four nebuliser systems tested produced over 80% of total drug output within the first five minutes of nebulisation. We suggest that five minutes is...

journal_title：Archives of disease in childhood

authors： O'Callaghan C,Clark AR,Milner AD

更新日期：1989-09-01 00:00:00

abstract：:The allergic response is distinct from other immune reactions in its reliance on IgE, its high affinity receptor, Fc epsilon RI, and the primary effector cell--the tissue mast cell. Positive skin tests or raised concentrations of specific immunoglobulin E (IgE) in the serum define IgE sensitisation or "atopy". IgE par...

journal_title：Archives of disease in childhood

authors： Milgrom H

更新日期：2003-01-01 00:00:00

abstract：:No consistent differences were found in mean heights and weights of 170 schoolchildren aged 6--12 years with the sickle cell trait and 1247 schoolchildren with normal haemoglobin living in Dominica and Jamaica. ...

journal_title：Archives of disease in childhood

authors： Ashcroft MT,Desai P,Grell GA,Serjeant BE,Serjeant GR

更新日期：1978-07-01 00:00:00

abstract：OBJECTIVE:The effect of adenoidectomy on nasopharyngeal colonisation of pathogens has not previously been evaluated. The authors studied the effect of adenoidectomy on nasopharyngeal colonisation by bacteria causing otitis media and the effect of adenoidectomy on the development of pneumococcal capsular polysaccharide ...

journal_title：Archives of disease in childhood

authors： Mattila PS,Hammarén-Malmi S,Saxen H,Kaijalainen T,Käyhty H,Tarkkanen J

更新日期：2010-09-01 00:00:00

abstract：:A significant proportion of children with anorectal malformations have long term problems with faecal continence. The psychological consequences of this chronic disability was assessed in 160 children and adolescents. The prevalence of clinically significant emotional problems among the sample overall, as assessed by ...

journal_title：Archives of disease in childhood

authors： Ludman L,Spitz L,Kiely EM

更新日期：1994-09-01 00:00:00

abstract：:Necrotising enterocolitis occurred in 3 infants after angiography at cardiac catheterisation. It is suggested that hypertonic contrast medium might have been responsible and that this complication could be avoided by the use of nonionic contrast media. ...

journal_title：Archives of disease in childhood

authors： Cooke RW,Meradji M,de Villeneuve VH

更新日期：1980-01-01 00:00:00

abstract：:Plasma testosterone was estimated by radioimmunoassay in 60 children with disorders of sexual development before and after stimulation with human chorionic gonadotrophin (HCG). In 21 children the testosterone levels after 3 and 5 daily injections of 1000 units HCG were compared and good correlation was found between t...

journal_title：Archives of disease in childhood

authors： Grant DB,Laurance BM,Atherden SM,Ryness J

更新日期：1976-08-01 00:00:00

abstract：AIMS:(1) To determine the pattern of respiratory impairment in children with thalassaemia major (TM); (2) to assess the relation between the degree of respiratory impairment and total body iron content. METHODS:Twenty nine TM patients were recruited. All underwent physical examination, standardised pulmonary function ...

journal_title：Archives of disease in childhood

authors： Li AM,Chan D,Li CK,Wong E,Chan YL,Fok TF

更新日期：2002-10-01 00:00:00

abstract：:Primary human herpesvirus 6 (HHV-6) and 7 (HHV-7) infections were identified in febrile children by qualitative and quantitative polymerase chain reaction (PCR) assays. Diagnosis was based on the differential detection of viral DNA in peripheral blood mononuclear cells (PBMC), but not in saliva. Six of 41 febrile infa...

journal_title：Archives of disease in childhood

authors： Clark DA,Kidd IM,Collingham KE,Tarlow M,Ayeni T,Riordan A,Griffiths PD,Emery VC,Pillay D

更新日期：1997-07-01 00:00:00