Pathogenesis of liver damage during parenteral nutrition: is lipofuscin a clue?

abstract：AIMS:To assess the impact of two paediatric intensive care unit retrieval teams on the performance of three mortality risk scoring systems: pre-ICU PRISM, PIM, and PRISM II. METHODS:A total of 928 critically ill children retrieved for intensive care from district general hospitals in the south east of England (crude m...

journal_title：Archives of disease in childhood

authors： Tibby SM,Taylor D,Festa M,Hanna S,Hatherill M,Jones G,Habibi P,Durward A,Murdoch IA

更新日期：2002-11-01 00:00:00

abstract：:The influence of physical housing quality on childhood asthma expression, especially the effect of exposure to moulds, allergens, and pollutants, is well documented. However, attempts to explain increasing rates and severity of childhood asthma solely through physical environmental factors have been unsuccessful, and ...

journal_title：Archives of disease in childhood

authors： Sandel M,Wright RJ

更新日期：2006-11-01 00:00:00

abstract：:In a five year period, 39 children (29 boys, 10 girls) aged 2 months to 13 years (mean 7.8 years) were studied who had suffered a major head injury (29 road traffic accidents, six falls, and four non-accidental injury). The injury had been assessed clinically and by cranial computed tomography or cranial ultrasound (i...

journal_title：Archives of disease in childhood

authors： Elias-Jones AC,Punt JA,Turnbull AE,Jaspan T

更新日期：1992-12-01 00:00:00

abstract：:Ethical considerations have long been a part of clinical decision making. However, just as doctors and healthcare professionals are being increasingly challenged about the evidence base for their practice, there is increasing focus on the ethical dimension of clinical care. ...

journal_title：Archives of disease in childhood

authors： Watson AR

更新日期：2005-09-01 00:00:00

abstract：OBJECTIVE:To examine the efficacy and safety of torasemide in children with chronic heart failure (HF). METHODS:102 children with chronic HF who had received oral torasemide were analysed. Of these, 62 (de novo group) were newly diagnosed as having HF and were given torasemide as a diuretic. The remaining 40 (replacem...

journal_title：Archives of disease in childhood

authors： Senzaki H,Kamiyama M,Masutani S,Ishido H,Taketazu M,Kobayashi T,Katogi T,Kyo S

更新日期：2008-09-01 00:00:00

abstract：:A 14-month-old girl with invasive perineal amoebiasis is reported. There was destruction of the anus, the rectovaginal septum, the pelvic floor, and the perineum. The rapid progress and destructive potential of perineal amoebiasis is noted and the benefits of diagnostic awareness emphasised. Treatment with metronidazo...

journal_title：Archives of disease in childhood

authors： Wynne JM

更新日期：1980-03-01 00:00:00

abstract：:Fundamental to appropriate nutritional prescription is an understanding of the conditions necessary for growth that include the requirements for energy in health and illness. Energy requirements need to be met by the dietary intake to prevent weight loss. A positive energy balance will result in weight gain. Energy re...

journal_title：Archives of disease in childhood

authors： Wiskin AE,Davies JH,Wootton SA,Beattie RM

更新日期：2011-06-01 00:00:00

abstract：:Thirty-two children with a past diagnosis of coeliac disease were reinvestigated by means of gluten challenge. They had received a gluten-free diet for a mean period of 6-5 years (range 0-25-11-0) before gluten challenge, and had a mean age of 9-9 years (range 3-0-15-3) at the onset of challenge. Small intestinal biop...

journal_title：Archives of disease in childhood

authors： Packer SM,Charlton V,Keeling JW,Risdon RA,Ogilvie D,Rowlatt RJ,Larcher VF,Harries JT

更新日期：1978-06-01 00:00:00

abstract：:Thirty nine infants with severe asphyxia (28 affected perinatally and 11 later) were studied by electrophysiological cerebral function monitoring (CFM) for periods varying from a half to 49 days. Nineteen infants died while still in intensive care and two died later from sequelae. Eighteen survived and were followed u...

journal_title：Archives of disease in childhood

authors： Bjerre I,Hellström-Westas L,Rosén I,Svenningsen N

更新日期：1983-12-01 00:00:00

abstract：BACKGROUND:Asthma is among the most common chronic diseases in childhood and is steadily increasing in prevalence. Better characterisation of factors that determine the risk of hospitalisation for atopic asthma in childhood may help design prevention programmes and improve our understanding of disease pathobiology. Thi...

journal_title：Archives of disease in childhood

authors： Kiechl-Kohlendorfer U,Horak E,Mueller W,Strobl R,Haberland C,Fink FM,Schwaiger M,Gutenberger KH,Reich H,Meraner D,Kiechl S

更新日期：2007-04-01 00:00:00

abstract：:The allergic response is distinct from other immune reactions in its reliance on IgE, its high affinity receptor, Fc epsilon RI, and the primary effector cell--the tissue mast cell. Positive skin tests or raised concentrations of specific immunoglobulin E (IgE) in the serum define IgE sensitisation or "atopy". IgE par...

journal_title：Archives of disease in childhood

authors： Milgrom H

更新日期：2003-01-01 00:00:00

abstract：:A four year regional screening programme to detect cystic fibrosis using measurement of immunoreactive trypsinogen is described. During this period 60 infants were diagnosed; 34 by screening, 12 born with meconium ileus, and 14 not identified by the screening assay but who presented with clinical symptoms at a later a...

journal_title：Archives of disease in childhood

authors： Roberts G,Stanfield M,Black A,Redmond A

更新日期：1988-12-01 00:00:00

abstract：OBJECTIVE:To assess differences across educational outcomes in survivors of childhood cancer (CCS) compared with peers. DESIGN:Systematic review and meta-analysis of observational studies. DATA SOURCES AND STUDY SELECTION:Medline, EMBASE, ERIC, CINAHL and PsycInfo from inception to 1st August 2018. Any peer reviewed,...

journal_title：Archives of disease in childhood

authors： Saatci D,Thomas A,Botting B,Sutcliffe AG

更新日期：2020-04-01 00:00:00

abstract：AIM:To test the hypothesis that overall intelligence quotient (IQ) is decreased in patients with Aarskog syndrome. METHODS:21 boys under 17 years of age with a confirmed clinical diagnosis of Aarskog syndrome were assessed using the Griffiths mental development scales and the British ability scales. RESULTS:IQ ranged...

journal_title：Archives of disease in childhood

authors： Logie LJ,Porteous ME

更新日期：1998-10-01 00:00:00

abstract：AIM:To investigate the safety of bronchoscopy and endobronchial biopsy in children with difficult asthma, and discuss the ethical issues associated with the procedure. METHODS:A three year prospective observational study was performed in two tertiary paediatric respiratory centres specialising in the management of chi...

journal_title：Archives of disease in childhood

authors： Payne D,McKenzie SA,Stacey S,Misra D,Haxby E,Bush A

更新日期：2001-05-01 00:00:00

abstract：:Analysis of the growth abnormalities in sickle cell disease has been limited by the lack of longitudinal observations in individuals, and by an inability to quantitate the observed patterns. To investigate the timing and pattern of the adolescent growth spurt, longitudinal observations of height from the Jamaican coho...

journal_title：Archives of disease in childhood

authors： Singhal A,Thomas P,Cook R,Wierenga K,Serjeant G

更新日期：1994-11-01 00:00:00

abstract：:A case of partial trisomy of the long arm of chromosome 3 (3q21 leads to qter) is described. The clinical findings are compared with those in 5 previously reported cases. There is hirsutism and characteristic facial dysmorphism, the common features of which are a square-shaped face, prominent nasal bridge, everted nos...

journal_title：Archives of disease in childhood

authors： Fear C,Briggs A

更新日期：1979-02-01 00:00:00

abstract：:We describe a non-progressive choreo-athetoid disorder of early onset, present in three families. There were no appreciable abnormalities in pregnancy, during the perinatal period, or in infancy. In each case the family history suggested transmission as an autosomal dominant trait, the gene showing diminished penetran...

journal_title：Archives of disease in childhood

authors： Sleigh G,Lindenbaum RH

更新日期：1981-08-01 00:00:00

abstract：BACKGROUND:The prevalence of thyroid disease is increased in Down's syndrome. Most available data come from cross sectional studies. AIMS:To study longitudinally thyroid function in patients with Down's syndrome in Uppsala county (85 patients) up to the age of 25 years. METHODS:Observational study based on yearly fol...

journal_title：Archives of disease in childhood

authors： Karlsson B,Gustafsson J,Hedov G,Ivarsson SA,Annerén G

更新日期：1998-09-01 00:00:00

abstract：:The auditory function of 370 infants, drawn from both low and high risk groups, was tested before postnatal discharge using three tests: standard auditory brain stem responses (ABR), automated analysis of ABR, and automated analysis of evoked otoacoustic emissions (OAE). All infants failing any neonatal test had furth...

journal_title：Archives of disease in childhood

authors： Kennedy CR,Kimm L,Dees DC,Evans PI,Hunter M,Lenton S,Thornton RD

更新日期：1991-10-01 00:00:00

abstract：:Safe and effective paediatric pharmacotherapy requires careful evaluation of the type of drug substance, the necessary dose and the age-appropriateness of the formulation. Generally, the younger the child, the more the attention that is required. For decades, there has been a general lack of (authorised) formulations ...

journal_title：Archives of disease in childhood

authors： van Riet-Nales DA,Schobben AF,Vromans H,Egberts TC,Rademaker CM

更新日期：2016-07-01 00:00:00

abstract：:The output of the drug and the particle size produced by various nebulisers were assessed, and sensible nebulisation times for sodium cromoglycate calculated. Three of the four nebuliser systems tested produced over 80% of total drug output within the first five minutes of nebulisation. We suggest that five minutes is...

journal_title：Archives of disease in childhood

authors： O'Callaghan C,Clark AR,Milner AD

更新日期：1989-09-01 00:00:00

abstract：BACKGROUND AND AIMS:There are few standardised questionnaires for the assessment of respiratory symptoms in preschool children. We have developed and tested the short-term repeatability of a postal questionnaire on respiratory symptoms for 1-year-old children. METHODS:A newly developed postal questionnaire for the ass...

journal_title：Archives of disease in childhood

authors： Strippoli MP,Silverman M,Michel G,Kuehni CE

更新日期：2007-10-01 00:00:00

abstract：BACKGROUND:Epidemics of enterovirus 71 infection have caused the death of many children throughout the world. Rhombencephalitis, brain stem encephalitis, and heart failure were present in all of the fatal cases. However, no evidence of myocarditis was noted in the heart specimens, and the mechanism of heart failure rem...

journal_title：Archives of disease in childhood

authors： Fu YC,Chi CS,Chiu YT,Hsu SL,Hwang B,Jan SL,Chen PY,Huang FL,Chang Y

更新日期：2004-04-01 00:00:00

abstract：:The fasting serum cholecystokinin-like activity was measured in 21 infants with pyloric stenosis and in 13 normal controls. No significant difference was found between the two groups. The basal acid secretion was measured by continuously aspirating the previously emptied stomach for one hour. The basal gastric volume ...

journal_title：Archives of disease in childhood

authors： Rogers IM,Drainer IK,Dougal AJ,Black J,Logan R

更新日期：1979-10-01 00:00:00

abstract：:A girl was born to a mother who had undergone treatment for epilepsy with carbamazepine during pregnancy. The infant had dysmorphic features and was physically and mentally retarded. We consider that the malformations were the result of the maternal treatment with carbamazepine. ...

journal_title：Archives of disease in childhood

authors： Vestermark V,Vestermark S

更新日期：1991-05-01 00:00:00

abstract：AIMS:To evaluate behavioural outcome and quality of life in children aged 8-14 years after neonatal arterial switch operation for transposition of the great arteries. METHODS:Sixty children operated as neonates with combined deep hypothermic circulatory arrest and low flow cardiopulmonary bypass were evaluated at age ...

journal_title：Archives of disease in childhood

authors： Hövels-Gürich HH,Konrad K,Wiesner M,Minkenberg R,Herpertz-Dahlmann B,Messmer BJ,Von Bernuth G

更新日期：2002-12-01 00:00:00

abstract：:Thyroid function was studied in 54 low birthweight infants during a 3-week period. Each infant was placed in one of three groups. Group 1 (n = 21), infants who were well and appropriately grown fro gestational age; group 2 (n = 23), infants who were appropriately grown but who had hyaline membrane disease; group 3 (n ...

journal_title：Archives of disease in childhood

authors： Uhrmann S,Marks KH,Maisels MJ,Kulin HE,Kaplan M,Utiger R

更新日期：1981-03-01 00:00:00

abstract：OBJECTIVE:To describe the significance of pericardial effusion (PE), mitral regurgitation (MR) and impaired systolic function in predicting coronary artery lesions (CAL) at diagnosis and follow-up in Kawasaki disease (KD). DESIGN:Echocardiographic records on admission, at 1-3 weeks of illness, and at 6-8 weeks of illn...

journal_title：Archives of disease in childhood

authors： Lega JC,Bozio A,Cimaz R,Veyrier M,Floret D,Ducreux C,Reix P,Di Filippo S

更新日期：2013-02-01 00:00:00

abstract：:The objectives of this study were to determine whether or not the probiotic Lactobacillus GG can colonise the immature bowel of premature infants and if so, does colonisation result in a reduction of the size of the bowel reservoir of nosocomial pathogens such as enterobacteriaceae, enterococci, yeasts or staphylococc...

journal_title：Archives of disease in childhood

authors： Millar MR,Bacon C,Smith SL,Walker V,Hall MA

更新日期：1993-11-01 00:00:00