Effects of co-exposure to noise and mixture of organic solvents on blood pressure.


OBJECTIVES:Independent exposure to noise or organic solvents is reported to be associated with cardiovascular effects, but the effect of joint exposure is unclear. The present study aimed to investigate effects of noise, a mixture of organic solvents (N,N-dimethylformamide (DMF) and toluene) and their interaction on hypertension. METHODS:We recruited 59 volunteers working in a synthetic leather manufacturing company during 2005-2006. Both personal noise exposure and airborne co-exposure to DMF and toluene at work were measured and used to calculate the mixed hazard index (HI). Multivariate logistic regressions were conducted to estimate between-group differences of hypertension by controlling for potential confounders. RESULTS:We found that 18 co-exposure workers (82.22 +/- 2.70 dBA and a mixed HI of 0.53 +/- 0.20) had the highest prevalence of hypertension (55.6%) compared to 15 solvent-exposure workers (a mixed HI of 0.32 +/- 0.18; 46.7%), 9 noise-exposure workers (84.13 +/- 2.30 dBA; 44.4%) and 17 low-exposure workers (11.8%). The adjusted odds ratio (OR) of hypertension compared to low-exposure workers increased from 7.9 times (95% confidence interval (CI)=0.9-66.3; p=0.06) in solvent-exposure workers and 9.1 times (OR=9.1, 95% CI=1.0-81.1; p<0.05) in noise-exposure workers to 13.5 times (95% CI=1.5-117.8; p<0.05) in co-exposure workers. CONCLUSIONS:Our findings suggest that co-exposure to noise, DMF and toluene is associated with hypertension in synthetic leather workers. Simultaneous exposure to noise and a mixture of organic solvents may have a sub-additive effect on the risk of hypertension.


J Occup Health


Chang TY,Wang VS,Hwang BF,Yen HY,Lai JS,Liu CS,Lin SY




Has Abstract


2009-01-01 00:00:00














  • Nickel-smelting fumes increased the expression of HIF-1α through PI3K/ERK pathway in NIH/3T3 cells.

    abstract:OBJECTIVE:The purpose of this study was to investigate the effects of Nickel (Ni) -smelting fumes on oncogenic proteins in vivo and in vitro. METHODS:Ni fallout beside a Ni smelting furnace in a factory was sampled to study its toxic effect. The effects of Ni-smelting fumes on the regulation of PI3K and ERK signaling ...

    journal_title:Journal of occupational health

    pub_type: 杂志文章


    authors: Han D,Yang Y,Zhang L,Wang C,Wang Y,Tan WQ,Hu XY,Wu YH

    更新日期:2016-09-30 00:00:00

  • Measurement of concentrations of thioglycolic acid, dithiodiglycolic acid and ammonia in indoor air of a beauty salon.

    abstract:OBJECTIVES:Among the many chemicals used in a hair salon, exposure to thioglycolic acid (TGA) used for permanent waving solutions (PWS) potentially causes adverse health effects. However, no report has been previously published on the indoor air concentrations of TGA in a beauty salon that contributes to assessment of ...

    journal_title:Journal of occupational health

    pub_type: 杂志文章


    authors: Oikawa D,Takeuchi W,Murata S,Takahashi K,Sekine Y

    更新日期:2012-01-01 00:00:00

  • Carcinogenicity of multi-walled carbon nanotubes: challenging issue on hazard assessment.

    abstract:OBJECTIVES:This report reviews the carcinogenicity of multi-walled carbon nanotubes (MWCNTs) in experimental animals, concentrating on MWNT-7, a straight fibrous MWCNT. METHODS:MWCNTs were administered to mice and rats by intraperitoneal injection, intrascrotal injection, subcutaneous injection, intratracheal instilla...

    journal_title:Journal of occupational health

    pub_type: 杂志文章


    authors: Fukushima S,Kasai T,Umeda Y,Ohnishi M,Sasaki T,Matsumoto M

    更新日期:2018-01-25 00:00:00

  • Assessment of exposure to voices and noise via earphones in manufacturing industry workers in Japan.

    abstract:OBJECTIVES:There is concern that sound via earphones and headphones attached to headsets used in workplaces may be a risk factor for noise-induced hearing loss (NIHL). Although there are some previous studies investigating exposure to noise from headphones, almost none have assessed the risks to workers who use earphon...

    journal_title:Journal of occupational health

    pub_type: 杂志文章


    authors: Nakao T,Kakei M,Araki I,Tsutsui T,Satoh N,Inoue J,Horie S

    更新日期:2014-01-01 00:00:00

  • Do we recover from vacation? Meta-analysis of vacation effects on health and well-being.

    abstract:OBJECTIVES:The aim of this meta-analysis is to investigate to what extent vacation has positive effects on health and well-being, how long such effects endure after work resumption, and how specific vacation activities and experiences affect these relationships. METHODS:Based on a systematic literature search (PsycInf...

    journal_title:Journal of occupational health

    pub_type: 杂志文章,meta分析,评审


    authors: de Bloom J,Kompier M,Geurts S,de Weerth C,Taris T,Sonnentag S

    更新日期:2009-01-01 00:00:00

  • Moderating effects of psychological job strain on the relationship between working hours and health: an examination of white-collar workers employed by a Japanese manufacturing company.

    abstract::The effects of working hours on health were examined taking psychological job strain into account. White-collar workers employed at the main office of a Japanese manufacturing company provided data for analysis done in 1997. The eligible subjects were 286 workers aged 20-39. Causal relationships between working hours,...

    journal_title:Journal of occupational health

    pub_type: 杂志文章


    authors: Tarumi K,Hagihara A,Morimoto K

    更新日期:2004-09-01 00:00:00

  • Association of job-related stress factors with psychological and somatic symptoms among Japanese hospital nurses: effect of departmental environment in acute care hospitals.

    abstract::The present study examined degrees of job-related stress factors as well as mental and physical symptoms among Japanese hospital nurses in various departments, and clarified associations of departments and job-related stress factors with those symptoms. A self-administered anonymous questionnaire was distributed to 1,...

    journal_title:Journal of occupational health

    pub_type: 杂志文章,多中心研究


    authors: Kawano Y

    更新日期:2008-01-01 00:00:00

  • How job demands affect an intimate partner: a test of the spillover-crossover model in Japan.

    abstract:OBJECTIVES:The present study examined how job demands affect an intimate partner's well-being. We hypothesized that job demands have a negative influence on partner well-being through the experience of work-family conflict (WFC) and an impaired quality of the relationship (reduced social support and increased social un...

    journal_title:Journal of occupational health

    pub_type: 杂志文章


    authors: Shimazu A,Bakker AB,Demerouti E

    更新日期:2009-01-01 00:00:00

  • Association between occupational clusters and allergic rhinitis in the Korean population: analysis of the Korean National Health and Nutrition Examination Survey data.

    abstract:OBJECTIVES:This study aimed to investigate the association between occupational clusters and allergic rhinitis (AR). METHODS:The study was based on data from the Korean National Health and Nutrition Examination Survey (KNHANES: 2007-2015). This study included 46,965 individuals: 20,491 men and 26,474 women. AR was def...

    journal_title:Journal of occupational health

    pub_type: 杂志文章


    authors: Park S,Jung PK,Choi M,Seok H,Kim H,Oh SS,Koh SB

    更新日期:2018-07-25 00:00:00

  • The Japanese Workplace PERMA-Profiler: A validation study among Japanese workers.

    abstract:OBJECTIVES:Although well-being at work is important for occupational health, multi-dimensional workplace well-being measures do not exist for Japanese workers. The purpose of this study was to investigate the validity of the Japanese version of the Workplace PERMA-Profiler. METHODS:Japanese workers completed online su...

    journal_title:Journal of occupational health

    pub_type: 杂志文章


    authors: Watanabe K,Kawakami N,Shiotani T,Adachi H,Matsumoto K,Imamura K,Matsumoto K,Yamagami F,Fusejima A,Muraoka T,Kagami T,Shimazu A,L Kern M

    更新日期:2018-09-26 00:00:00

  • The usefulness of sleep apnea syndrome screening using a portable pulse oximeter in the workplace.

    abstract::Sleep Apnea Syndrome (SAS) is a condition characterized by sleep-disordered breathing resulting in health impairment and sleep problems. From the viewpoints of the prevention of health impairment, accidents at work and traffic accidents, active implementation of screening for SAS in workplaces is necessary. Using a po...

    journal_title:Journal of occupational health

    pub_type: 杂志文章


    authors: Niijima K,Enta K,Hori H,Sashihara S,Mizoue T,Morimoto Y

    更新日期:2007-01-01 00:00:00

  • Fire risk assessment in fire hazardous zones of gasoline stations.

    abstract:OBJECTIVE:This cross-sectional study aimed to assess fire risk in fire hazardous zones (FHZ) at the dispenser areas of gasoline stations. METHODS:There were 47 stations chosen for fire risk assessment and two zones around the dispenser area of each station were assessed. The assessments were carried out by applying th...

    journal_title:Journal of occupational health

    pub_type: 杂志文章


    authors: Chaiklieng S,Dacherngkhao T,Suggaravetsiri P,Pruktharathikul V

    更新日期:2020-01-01 00:00:00

  • The association of work-related stressors and their changes over time with the development of metabolic syndrome: The Furukawa Nutrition and Health Study.

    abstract:OBJECTIVE:To investigate associations of work-related stressors and their changes over time with the risk of developing metabolic syndrome (MetS) among Japanese manufacturing workers. METHODS:Participants were 1,040 employees aged 19 to 68 years who were free from MetS at baseline and completed the three year-interval...

    journal_title:Journal of occupational health

    pub_type: 杂志文章


    authors: Yamaguchi M,Eguchi M,Akter S,Kochi T,Hu H,Kashino I,Kuwahara K,Kabe I,Mizoue T

    更新日期:2018-11-27 00:00:00

  • Quality of life among district hospital nurses with multisite musculoskeletal symptoms in Vietnam.

    abstract:BACKGROUND:Nurses are one of the population groups with the highest prevalence of musculoskeletal disorders (MSDs). At many sites, musculoskeletal symptoms (MS) represent a major health-care burden, adversely affecting nurses' quality of life and giving rise to mental health issues. OBJECTIVES:This study measured the ...

    journal_title:Journal of occupational health

    pub_type: 杂志文章


    authors: Nguyen TH,Hoang DL,Hoang TG,Pham MK,Nguyen VK,Bodin J,Dewitte JD,Roquelaure Y

    更新日期:2020-01-01 00:00:00

  • Prevalence and associated factors for thoracic spine pain in the adult working population: a literature review.

    abstract:OBJECTIVES:Spinal pain is a significant occupational health issue. Whilst neck pain and low back pain have received considerable attention, thoracic spinal pain (TSP) has not. The objective of this study was to systematically identify and report the evidence describing the prevalence and correlates of TSP within occupa...

    journal_title:Journal of occupational health

    pub_type: 杂志文章,评审


    authors: Briggs AM,Bragge P,Smith AJ,Govil D,Straker LM

    更新日期:2009-01-01 00:00:00

  • Effects of fatigue on immune function in nurses performing shift work.

    abstract:OBJECTIVES:We investigated the effects of fatigue on NK cell function and lymphocyte subpopulations in nurses performing shift work using a longitudinal design. METHODS:Fifty-seven female nurses engaged in shift work at a hospital in Japan were selected for our study cohort. The hospital used a counterclockwise rotati...

    journal_title:Journal of occupational health

    pub_type: 杂志文章


    authors: Nagai M,Morikawa Y,Kitaoka K,Nakamura K,Sakurai M,Nishijo M,Hamazaki Y,Maruzeni S,Nakagawa H

    更新日期:2011-01-01 00:00:00

  • Allyl nitrile: Toxicity and health effects.

    abstract:OBJECTIVES:Allyl nitrile (3-butenenitrile) occurs naturally in the environment, in particular, in cruciferous vegetables, indicating a possible daily intake of the compound. There is no report on actual health effects of allyl nitrile in humans, although it is possible that individuals in the environment are at a risk ...

    journal_title:Journal of occupational health

    pub_type: 杂志文章,评审


    authors: Tanii H

    更新日期:2017-03-28 00:00:00

  • Competencies required for occupational health nurses.

    abstract:OBJECTIVES:For occupational health (OH) nurses to perform activities effectively, not only skills and knowledge but also competencies proposed by Dr. McClelland are indispensable. This study aimed to identify competencies required for OH nurses and to show their structure diagram. METHODS:Qualitative descriptive resea...

    journal_title:Journal of occupational health

    pub_type: 杂志文章


    authors: Kono K,Goto Y,Hatanaka J,Yoshikawa E

    更新日期:2017-11-25 00:00:00

  • Changes over time in pulmonary inflammatory response in rat lungs after intratracheal instillation of nickel oxide nanoparticles.

    abstract:OBJECTIVE:Nickel oxide nanoparticles (NiONPs) are representative metal oxide NPs and are categorized as an insoluble nickel compound. Our previous studies suggested that NiONPs have more pulmonary toxicity than micron-sized NiO because they may dissolve slowly and produce many more Ni ions. We confirmed the hypothesis ...

    journal_title:Journal of occupational health

    pub_type: 杂志文章


    authors: Nishi KI,Kadoya C,Ogami A,Oyabu T,Morimoto Y,Ueno S,Myojo T

    更新日期:2020-01-01 00:00:00

  • Interactive model of subsidiary behaviors, work performance and autonomic nerve activity during visual display terminal work.

    abstract:OBJECTIVES:The aims of the study were to investigate the systematic classification of subsidiary behaviors during visual display terminal (VDT) work and discuss the interpretation of these behaviors through an interactive model of subsidiary behaviors, work performance and autonomic nerve activity. METHODS:Twelve univ...

    journal_title:Journal of occupational health

    pub_type: 杂志文章


    authors: Takanishi T,Ebara T,Murasaki GI,Kubo T,Tachi N,Itani T,Kamijima M

    更新日期:2010-01-01 00:00:00

  • Comparison of single or multiple intratracheal administration for pulmonary toxic responses of nickel oxide nanoparticles in rats.

    abstract:OBJECTIVES:In this study, we focused on the qualitative and quantitative differences of the lung lesions induced by single or multiple intratracheal administration of nickel oxide nanoparticles (NiO). METHODS:Male rats were randomized into groups receiving intratracheal administrations in a single dose or two to four ...

    journal_title:Journal of occupational health

    pub_type: 杂志文章


    authors: Senoh H,Kano H,Suzuki M,Ohnishi M,Kondo H,Takanobu K,Umeda Y,Aiso S,Fukushima S

    更新日期:2017-03-28 00:00:00

  • Changes in health habits of female shift workers.

    abstract::This paper examines the effects of shift work on the lifestyles of female factory workers. As an indicator of healthy lifestyle habits, we used a scoring system (referred to below as the 'health score') based on Lester Breslow's health habits. The 'health score' of the women was higher than that of the men, but the sh...

    journal_title:Journal of occupational health

    pub_type: 杂志文章


    authors: Kaneko SY,Maeda T,Sasaki A,Sato A,Tanaka K,Kobayashi T,Tanaka M,Fukushima T

    更新日期:2004-05-01 00:00:00

  • Possible changes of New-Generation inflammation markers with occupational lead exposure.

    abstract:OBJECTIVES:Occupational lead (Pb) exposure is still an important health problem in the world. Long-term Pb exposure causes several adverse effects. The aim of this study was to investigate the changes of inflammation markers with chronic Pb exposure by analyzing neopterin levels and kynurenine (Kyn) to tryptophan (Trp)...

    journal_title:Journal of occupational health

    pub_type: 杂志文章


    authors: Sipahi H,Girgin G,Palabiyik SS,Tutkun E,Yilmaz OH,Baydar T

    更新日期:2017-07-27 00:00:00

  • Determining of crystalline silica in respirable dust samples by infrared spectrophotometry in the presence of interferences.

    abstract::Infrared Spectrophotometry (IR) is now widely used to determine crystalline silica in industrial dust samples. Though the IR method has many advantages when dealing with respirable dust samples, some serious analytical errors are often caused by interference minerals contamination. These minerals have a characteristic...

    journal_title:Journal of occupational health

    pub_type: 杂志文章


    authors: Ojima J

    更新日期:2003-03-01 00:00:00

  • Life in company dormitories and a career change are associated with anxiety over lack of privacy among radiation decontamination workers in Fukushima Prefecture, Japan.

    abstract:OBJECTIVES:The purpose of the present study was to obtain knowledge for improvement of the housing and life among radiation decontamination workers by examining the effect of housing type on anxiety over lack of privacy. METHODS:This cross-sectional study comprised 544 male radiation decontamination workers in Fukushi...

    journal_title:Journal of occupational health

    pub_type: 杂志文章


    authors: Hidaka T,Kakamu T,Endo S,Sato S,Masuishi Y,Kumagai T,Nakano S,Koyama K,Fukushima T

    更新日期:2018-09-26 00:00:00

  • Pulmonary toxicity in mice by 2- and 13-week inhalation exposures to indium-tin oxide and indium oxide aerosols.

    abstract:OBJECTIVES:Inhalation toxicities of indium-tin oxide (ITO) and indium oxide (IO) in mice were characterized in comparison with those previously reported in rats. METHODS:B6C3F(1) mice of both sexes were exposed by inhalation to ITO or IO aerosol for 6 h/day, 5 day/wk for 2 wk at 0, 0.1, 1, 10 or 100 mg/m(3) or 13 wk a...

    journal_title:Journal of occupational health

    pub_type: 杂志文章


    authors: Nagano K,Nishizawa T,Eitaki Y,Ohnishi M,Noguchi T,Arito H,Fukushima S

    更新日期:2011-01-01 00:00:00

  • Biological monitoring of exposure: trends and key developments.

    abstract::The concept of biological monitoring (BM) has gained the special interest of individual scientists and international organizations. Today, when analytical problems have almost ceased due to new laboratory techniques and quality assurance systems, the methods for interpretation of results have become the most important...

    journal_title:Journal of occupational health

    pub_type: 杂志文章,评审


    authors: Jakubowski M,Trzcinka-Ochocka M

    更新日期:2005-01-01 00:00:00

  • The influence of the thermal modification of pine (Pinus sylvestris L.) wood on the creation of fine dust particles in plane milling: Fine dust creation in the plane milling of thermally modified pine wood.

    abstract:OBJECTIVES:The aim of the study was to determine the effect of parameters of the thermal modification process and machining on the size distribution of dust particles of Scots pine (Pinus sylvestris L.) generated during lengthwise milling. METHOD:Unmodified wood and thermally modified wood at temperatures of 130, 160,...

    journal_title:Journal of occupational health

    pub_type: 杂志文章


    authors: Piernik M,Rogoziński T,Krauss A,Pinkowski G

    更新日期:2019-11-01 00:00:00

  • Perfluorooctanoate and perfluorooctane sulfonate concentrations in surface water in Japan.

    abstract::Perfluorooctanoate (PFOA) and perfluorooctane sulfonate (PFOS) are synthetic surfactants used in Japan. An epidemiological study of workers exposed to PFOA revealed a significant increase in prostate cancer mortality. A cross-sectional study of PFOA-exposed workers showed that PFOA perturbs sex hormone homeostasis. We...

    journal_title:Journal of occupational health

    pub_type: 杂志文章


    authors: Saito N,Harada K,Inoue K,Sasaki K,Yoshinaga T,Koizumi A

    更新日期:2004-01-01 00:00:00

  • Effects of web-based supervisor training on job stressors and psychological distress among workers: a workplace-based randomized controlled trial.

    abstract::Using workplaces as a unit for randomization, a randomized controlled trial was conducted to determine the effects of web-based supervisor training on the subject of worksite mental health on job stressors, supervisor support and psychological distress among subordinate workers. A total of eight workplaces of a sales ...

    journal_title:Journal of occupational health

    pub_type: 杂志文章,随机对照试验


    authors: Kawakami N,Takao S,Kobayashi Y,Tsutsumi A

    更新日期:2006-01-01 00:00:00