Do users of the intrauterine system (Mirena) have different genital symptoms and vaginal flora than users of the intrauterine contraceptive device?

Abstract:

:The copper intrauterine contraceptive device (IUCD) is strongly associated with bacterial vaginosis (BV). Hormonal influences may play a role in the control of vaginal flora. It is unclear whether use of the progesterone-incorporated intrauterine system (IUS; Mirena) is associated with abnormal vaginal flora or genital symptoms. One hundred and seventy-two women were assessed for symptoms and abnormal vaginal flora prior to and at intervals after insertion of either a copper IUCD or an IUS. Women were significantly more likely to have developed an abnormal vaginal discharge 4-6 weeks after insertion of an IUCD compared with an IUS (27% cf. 14%, P = 0.04), although this trend was not significant six months postinsertion. More women with an IUCD developed BV compared with an IUS at 4-6 weeks and six months. However, there were insufficient numbers of women with BV to demonstrate any significant difference between the vaginal flora of the two groups.

journal_name

Int J STD AIDS

authors

Neale R,Knight I,Keane F

doi

10.1258/ijsa.2008.008391

subject

Has Abstract

pub_date

2009-06-01 00:00:00

pages

423-4

issue

6

eissn

0956-4624

issn

1758-1052

pii

20/6/423

journal_volume

20

pub_type

临床试验,杂志文章
  • Improvement of the patient flow in a large urban clinic with high HIV seroprevalence in Kampala, Uganda.

    abstract::Antiretroviral treatment roll-out programmes in Africa often have difficulties to cope with the increasing number of clients. Based on the findings of a survey carried out in 2005 that showed long waiting times, innovative organizational changes (nurse visits and pharmacy-only refill visits) were introduced in our cli...

    journal_title:International journal of STD & AIDS

    pub_type: 杂志文章

    doi:10.1258/ijsa.2008.008174

    authors: Castelnuovo B,Babigumira J,Lamorde M,Muwanga A,Kambugu A,Colebunders R

    更新日期:2009-02-01 00:00:00

  • Enhanced surveillance of syphilis cases among men who have sex with men in London, October 2016-January 2017.

    abstract::Syphilis rates have been increasing in men who have sex with men (MSM) in London. To describe risk behaviour and refine public health interventions, we conducted prospective enhanced surveillance of new syphilis cases in MSM attending selected London sexual health clinics (SHCs) between October 2016 and January 2017. ...

    journal_title:International journal of STD & AIDS

    pub_type: 杂志文章

    doi:10.1177/0956462418814998

    authors: Rana S,Macdonald N,French P,Jarman J,Patel S,Portman M,Suchak T,Sullivan A,White J,Crook P

    更新日期:2019-04-01 00:00:00

  • The potential risks of probiotics among HIV-infected persons: Bacteraemia due to Lactobacillus acidophilus and review of the literature.

    abstract::Lactobacillus sp. are commensal organisms that are increasingly reported to cause invasive infections among immunosuppressed persons. However, few data exist regarding the occurrence and risk factors of these infections among HIV-infected persons. Further, the safety of products that contain lactobacilli (e.g. probiot...

    journal_title:International journal of STD & AIDS

    pub_type: 杂志文章,评审

    doi:10.1177/0956462415590725

    authors: Haghighat L,Crum-Cianflone NF

    更新日期:2016-11-01 00:00:00

  • Microcalcification of testis presenting as epididymo-orchitis.

    abstract::We report two cases who attended the genitourinary medicine clinic for the treatment of epididymo-orchitis. They did not respond to treatment and subsequent ultrasound sonography (USS) of testis confirmed microlithiasis and excluded any inflammatory process or carcinoma in situ. Because of its association with testicu...

    journal_title:International journal of STD & AIDS

    pub_type: 杂志文章

    doi:10.1258/ijsa.2007.007184

    authors: Mohanty K

    更新日期:2008-04-01 00:00:00

  • Candida infections in AIDS patients.

    abstract::In 1987, data from the Centers for Disease Control AIDS data base indicated a 50% prevalence of oropharyngeal Candida infection, a 10% rate of esophageal infection, and .5% rate of bronchopulmonary infection among AIDS patients. Candida-positive blood cultures were found in 13 of 903 AIDS patients, and disseminated C...

    journal_title:International journal of STD & AIDS

    pub_type: 社论

    doi:10.1177/095646249200300301

    authors: Odds FC

    更新日期:1992-05-01 00:00:00

  • The adherence to antiretroviral treatment evaluated from a hospital pharmacy: importance of the protease inhibitors pharmacological class.

    abstract::The goal of this study was to develop an evaluation method of antiretroviral treatment adherence from a hospital pharmacy and to identify one or more factors that influenced this adherence, such as patient or treatment characteristics. The HIV patients included in this study were based, for the major part, in Saint-An...

    journal_title:International journal of STD & AIDS

    pub_type: 杂志文章

    doi:10.1258/0956462053888826

    authors: Rubio M,Pédeboscq S,Ekouevi D,Zalabadi K,Chêne G,Bonarek M,Pometan JP

    更新日期:2005-05-01 00:00:00

  • Partnership duration and HIV serodisclosure among people living with HIV/AIDS in Lilongwe, Malawi.

    abstract::HIV serodisclosure to sexual partners is an important aspect of HIV prevention, treatment, and care. We investigated the association between partnership duration and serodisclosure among HIV-infected individuals in Lilongwe, Malawi. We analyzed data from a cross-sectional study of individuals attending one of two anti...

    journal_title:International journal of STD & AIDS

    pub_type: 杂志文章

    doi:10.1177/0956462418769730

    authors: Mbichila TH,Chagomerana M,Tang JH,Haddad LB,Hosseinipour MC,Tweya H,Phiri S

    更新日期:2018-09-01 00:00:00

  • Particular clinical presentations of psoriasis in HIV patients.

    abstract::Patients with HIV infection have a higher propensity for infectious, inflammatory, neoplastic and metabolic disorders. The link with psoriasis vulgaris is explained by well-known pathophysiological phenomena and can be observed at any stage of infection. The aim of our study was to characterize the clinical spectrum o...

    journal_title:International journal of STD & AIDS

    pub_type: 杂志文章

    doi:10.1258/ijsa.2011.010525

    authors: Fernandes S,Pinto GM,Cardoso J

    更新日期:2011-11-01 00:00:00

  • Testicular self-examination amongst genitourinary medicine clinic attendees.

    abstract::Advancements in the diagnosis and treatment of testicular cancer now give a five-year survival rate of 97.2%. Delayed presentation remains the primary cause of poor outcome and recommendations have stressed that men, particularly those with risk factors, should undertake regular testicular self-examination. This study...

    journal_title:International journal of STD & AIDS

    pub_type: 杂志文章

    doi:10.1177/0956462414522774

    authors: Kennett A,Shaw JW,Woolley PD

    更新日期:2014-10-01 00:00:00

  • Clinical value of C-reactive protein measurements in HIV-positive patients.

    abstract::The acute-phase protein C-reactive protein (CRP) is a sensitive marker of inflammation and tissue damage. We measured CRP in 109 HIV-1 antibody-positive patients admitted to hospital for investigation. In 67 patients with intercurrent infection (of whom 27 were afebrile at presentation) CRP levels were 2.2-483.5 mg/dL...

    journal_title:International journal of STD & AIDS

    pub_type: 杂志文章

    doi:10.1258/0956462054094006

    authors: Noursadeghi M,Miller RF

    更新日期:2005-06-01 00:00:00

  • Anaerobic vaginosis: study of male sexual partners.

    abstract::One hundred male sexual partners of women with anaerobic vaginosis (AV) were screened for the presence of sexually transmitted diseases (STD). Thirty male partners had evidence of non-gonococcal urethritis (NGU), compared to 5 in the control group (P less than 0.05). Chlamydia trachomatis was isolated from 14 male par...

    journal_title:International journal of STD & AIDS

    pub_type: 杂志文章

    doi:10.1177/095646249100200204

    authors: Arumainayagam JT,de Silva Y,Shahmanesh M

    更新日期:1991-03-01 00:00:00

  • Factors associated with sexually transmitted diseases among prostitutes in Singapore.

    abstract::From June to December 1990, 806 prostitutes registered with the STD programme in Singapore for regular screening for sexually transmitted diseases (STD) were investigated for factors associated with STD incidence in the preceding year. The majority were foreigners (92.7% Malaysians and 3.1% Thais). Anal sex (0.4%) and...

    journal_title:International journal of STD & AIDS

    pub_type: 杂志文章

    doi:10.1177/095646249200300506

    authors: Wong ML,Tan TC,Ho ML,Lim JY,Wan S,Chan R

    更新日期:1992-09-01 00:00:00

  • Evaluating the care cascade after antiretroviral therapy initiation in Latin America.

    abstract::Accelerating antiretroviral therapy (ART) administration, improving retention, and achieving viral suppression in low- and middle-income countries must be prioritized. We evaluated trends and disparities in these milestones in a large Latin American cohort. Adults starting ART (ARTstart) from 2003 to 2014 at Caribbean...

    journal_title:International journal of STD & AIDS

    pub_type: 杂志文章

    doi:10.1177/0956462417714094

    authors: Wolff MJ,Cortes CP,Mejìa FA,Padgett D,Belaunzarán-Zamudio P,Grinsztejn B,Giganti MJ,McGowan CC,Rebeiro PF,Caribbean, Central and South America network for HIV epidemiology (CCASAnet).

    更新日期:2018-01-01 00:00:00

  • Serological approaches to subtyping of HIV-1 in injecting drug users in Russia: evidence of subtype homogeneity at the main sites of the epidemic.

    abstract::The aim of this study was to develop and evaluate a simple V3 peptide-based enzyme immunoassay (PEIA) for large-scale serotyping of HIV-1 specimens derived from injecting drug users (IDUs) in the Russian Federation. Two synthetic peptides were evaluated, named P1 (RKSIHIGPGRAFYATGD) and P2 (RTSVRIGPGQVFYKTGD), in an P...

    journal_title:International journal of STD & AIDS

    pub_type: 杂志文章

    doi:

    authors: Bobkova MR,Kazennova EV,Selimova LM,Buravtsova EV,Lister S,Prilipov AG,Weber JN,Pokrovsky VV,Bobkov AF

    更新日期:2001-01-01 00:00:00

  • Factors associated with vertical HIV transmission during two different time periods: the impact of zidovudine use on clinical practice at a Brazilian reference centre.

    abstract::Vertical HIV transmission rates and associated factors among mother-infant pairs cared for at a Brazilian reference centre from 1988 to 1993 (period 1), and from 1996 to 1999 (period 2) were evaluated. A total of 150 and 239 infants born to HIV+ mothers were enrolled at birth during these periods. No zidovudine prophy...

    journal_title:International journal of STD & AIDS

    pub_type: 杂志文章

    doi:10.1258/095646203322556156

    authors: Mussi-Pinhata MM,Kato CM,Duarte G,Paschoini MC,Bettiol H,Quintana SM

    更新日期:2003-12-01 00:00:00

  • Sexually transmitted diseases in men in Mogadishu, Somalia.

    abstract::The prevalence of viral and bacterial sexually transmitted diseases were studied in 101 men attending a dermatovenereal outpatient clinic in Mogadishu. A control group of 103 healthy adult men were included for the serological part of the study. Serological markers of hepatitis B virus (HBV), human immunodeficiency vi...

    journal_title:International journal of STD & AIDS

    pub_type: 杂志文章

    doi:10.1177/095646249000100206

    authors: Ismail SO,Ahmed HJ,Grillner L,Hederstedt B,Issa A,Bygdeman SM

    更新日期:1990-03-01 00:00:00

  • Detecting asymptomatic Trichomonas vaginalis in females using the BD ProbeTec™ Trichomonas vaginalis Qx nucleic acid amplification test.

    abstract::Trichomonas vaginalis (TV) rates in women are increasing and many are asymptomatic. Nucleic acid amplification tests (NAATs) are becoming the 'gold standard' for diagnosis. We aimed to establish our asymptomatic TV rates by testing all women attending Oxfordshire's Sexual Health service, regardless of symptoms, using ...

    journal_title:International journal of STD & AIDS

    pub_type: 杂志文章

    doi:10.1177/0956462416649888

    authors: Lord E,Newnham T,Dorrell L,Jesuthasan G,Clarke L,Jeffery K,Sherrard J

    更新日期:2017-03-01 00:00:00

  • Vulvodynia--new and more effective approaches to therapy.

    abstract::Two cases are described of treatment-resistant vulvodynia that responded well to gabapentin. Gabapentin, an anti-epileptic drug, has been used in the treatment of neuropathic pain such as diabetic neuropathy and post-herpetic neuralgia. However, there has been little experience of its use in the relief of symptoms in ...

    journal_title:International journal of STD & AIDS

    pub_type: 杂志文章

    doi:10.1258/0956462021924802

    authors: Bates CM,Timmins DJ

    更新日期:2002-03-01 00:00:00

  • HIV prevalence and associated risk factors among female sex workers in Dar es Salaam, Tanzania: tracking the epidemic.

    abstract::Since 2014, HIV care and treatment services among key populations including female sex workers (FSWs) have intensified in Tanzania. We sought to track the epidemic among FSWs in Dar es Salaam, Tanzania. We conducted a cross-sectional integrated bio-behavioral survey using respondent-driven sampling and a structured qu...

    journal_title:International journal of STD & AIDS

    pub_type: 杂志文章

    doi:10.1177/0956462420917848

    authors: Mizinduko MM,Moen K,Likindikoki S,Mwijage A,Leyna GH,Makyao N,Leshabari MT,Ramadhan A,Kambi MB,Meyrowitsch D,Tersbøl B,Mmbaga EJ

    更新日期:2020-09-01 00:00:00

  • Pediculosis pubis: presentation to ophthalmologist as pthriasis palpebrarum associated with corneal epithelial keratitis.

    abstract::Pthiriasis palpebrarum caused by infestation with Pthirus pubis (crab louse) draws attention to pediculosis in the pubic and inguinal region. As pthiriasis is usually transmitted by sexual contact, many cases are likely to have other sexually transmitted diseases. A multidisciplinary approach is essential in the manag...

    journal_title:International journal of STD & AIDS

    pub_type: 杂志文章

    doi:10.1258/095646206777323445

    authors: Manjunatha NP,Jayamanne GR,Desai SP,Moss TR,Lalik J,Woodland A

    更新日期:2006-06-01 00:00:00

  • An aggressive neuroendocrine tumour in a man with AIDS.

    abstract::Pancreatic neuroendocrine tumours (PETs), though rare, are usually slow growing tumours with a relatively good prognosis. We describe a case of an aggressive malignant neuroendocrine tumour of the pancreas occurring in an AIDS patient, which has not been reported previously. ...

    journal_title:International journal of STD & AIDS

    pub_type: 杂志文章

    doi:10.1258/0956462011922841

    authors: Cox M,Joseph AT,Sharma N,Heaney O,Hock YL

    更新日期:2001-04-01 00:00:00

  • Direct observation therapy-highly active antiretroviral therapy in a resource-limited setting: the use of community treatment support can be effective.

    abstract::This study examines the use of various direct observation therapy-HAART treatment support modalities in Jos, Nigeria. A 12-month observational study enrolling 175 antiretroviral naïve patients into four arms of direct observation therapy-HAART (highly active antiretroviral therapy); daily observed therapy (DOT), twice...

    journal_title:International journal of STD & AIDS

    pub_type: 临床试验,杂志文章

    doi:10.1258/095646207782212252

    authors: Idoko JA,Agbaji O,Agaba P,Akolo C,Inuwa B,Hassan Z,Akintunde L,Badung B,Muazu M,Danang M,Imade G,Sankale JL,Kanki P

    更新日期:2007-11-01 00:00:00

  • Megestrol acetate vs cyproheptadine in the treatment of weight loss associated with HIV infection.

    abstract::Two appetite stimulants, megestrol acetate and cyproheptadine were administered in a randomized trial to 14 patients who had no evidence of opportunistic infection or malabsorption but were wasted (had lost more than 5 kg body weight) as a result of human immunodeficiency virus (HIV) infection. Energy intakes were cal...

    journal_title:International journal of STD & AIDS

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1177/095646249200300409

    authors: Summerbell CD,Youle M,McDonald V,Catalan J,Gazzard BG

    更新日期:1992-07-01 00:00:00

  • Clinical standards for the screening and management of acquired syphilis in HIV-positive adults.

    abstract::These clinical standards for the screening and management of acquired syphilis in HIV-positive patients in the UK were first made available on the MSSVD website in February 2002. They have been updated by the 2006 UK National Guideline on the Sexual Health of People with HIV which is also published in this issue of th...

    journal_title:International journal of STD & AIDS

    pub_type: 指南,杂志文章

    doi:10.1258/095646206778113096

    authors: Nandwani R,Fisher M,Medical Society for the Study of Venereal Diseases HIV Special Interest Group.

    更新日期:2006-09-01 00:00:00

  • BASHH Scotland/Scottish HIV and AIDS group national audit 2009-2010: sexual health care for people living with HIV.

    abstract::A national Scottish audit of 282 patients with HIV infection attending 11 clinics showed the following levels of performance against quality improvement Scotland Sexual Health Services Standards: syphilis serology was offered in the previous six months to 55% of patients (range: 12-97% of patients in individual clinic...

    journal_title:International journal of STD & AIDS

    pub_type: 杂志文章

    doi:10.1258/ijsa.2011.011379

    authors: Hembrom R,Goodall L,Bateman V,MacDonald R,Syed A,Taylor R,Clutterbuck DJ

    更新日期:2012-06-01 00:00:00

  • Seroprevalence of HSV-1 and HSV-2 antibodies in Canadian women screened for enrolment in a herpes simplex virus vaccine trial.

    abstract::Herpes simplex virus 1 and 2 (HSV-1 and HSV-2) infections continue to be among the most common and unrecognized sexually transmitted infections in the world. Although treatable, HSV-1 and HSV-2 infections remain incurable. Hence, there is interest in the development of a vaccine to prevent genital herpes. As part of a...

    journal_title:International journal of STD & AIDS

    pub_type: 杂志文章,随机对照试验

    doi:10.1177/0956462412472822

    authors: Gorfinkel IS,Aoki F,McNeil S,Dionne M,Shafran SD,Zickler P,Halperin S,Langley J,Bellamy A,Schulte J,Heineman T,Belshe R

    更新日期:2013-05-01 00:00:00

  • Two for the price of one.

    abstract::This case is about an HIV seropositive young woman referred for the treatment of severe menorrhagia causing anaemia due to adenomyosis where the levonorgestrel-releasing intrauterine system (Mirena) proved useful in treating her heavy periods and also provided effective contraception without interference from the live...

    journal_title:International journal of STD & AIDS

    pub_type: 杂志文章

    doi:10.1258/ijsa.2008.008107

    authors: Samuel MI,Tenant-Flowers M,Kumar U,Taylor C

    更新日期:2008-10-01 00:00:00

  • Effect of HIV genotypic drug resistance testing on the management and clinical course of HIV-infected children and adolescents.

    abstract::The clinical utility of genotypic drug resistance testing (DRT) in HIV-infected children on antiretroviral therapy (ART) is not well understood. HIV-infected patients aged <19 years undergoing DRT for virological failure were retrospectively enrolled. Indications for DRT and changes in HIV RNA load were recorded. Betw...

    journal_title:International journal of STD & AIDS

    pub_type: 杂志文章

    doi:10.1177/0956462412473958

    authors: Dehority W,Deville JG,Lujan-Zilbermann J,Spector SA,Viani RM

    更新日期:2013-07-01 00:00:00

  • A review of controlled trials in the pharmacological treatment of premature ejaculation.

    abstract::Premature ejaculation is a common sexual problem which presents to genitourinary (GU) medicine services. Five main treatment approaches have been used in clinical trials: behavioural therapy, antidepressants, phosphodiesterase-5 (PDE5) inhibitors, topical anaesthetic agents and alpha-blockers. We have carried out a sy...

    journal_title:International journal of STD & AIDS

    pub_type: 杂志文章,评审

    doi:10.1258/095646205774357299

    authors: Richardson D,Green J,Ritcheson A,Goldmeier D,Harris JR

    更新日期:2005-10-01 00:00:00

  • The management of Chlamydia trachomatis in genitourinary medicine clinics: a national audit in 2004.

    abstract::The first national audit of the management of Chlamydia trachomatis was undertaken by non-consultant career grade doctors working in genitourinary (GU) medicine clinics in the UK. During the audit period of January--March 2004, 1670 data collection forms were completed (from 830 men and 840 women with chlamydia). In a...

    journal_title:International journal of STD & AIDS

    pub_type: 杂志文章

    doi:10.1258/0956462054308431

    authors: Challenor R,Pinsent S,Chandramani S,Theobald N,Daniels D

    更新日期:2005-07-01 00:00:00