Fibrillation and accelerated AChR degradation in long-term muscle organ culture.

abstract：:Ocular movements and coordination require complex and integrated functions of somatic and autonomic nervous systems. Neurological disorders affecting these nervous systems may cause ocular dysfunction involving extraocular muscles and pupils. In this article, the prevalence, clinical presentations, and management of o...

journal_title：Muscle & nerve

authors： Evliyaoglu F,Karadag R,Burakgazi AZ

更新日期：2012-11-01 00:00:00

abstract：:The aim of this investigation was to define the boundaries of compound motor action potential (CMAP) dispersion, amplitude decay, and area decay in a control population and determine their dependence on external variables such as age and interelectrode distance. Measurements were made from median, ulnar, and common pe...

journal_title：Muscle & nerve

authors： Taylor PK

更新日期：1993-11-01 00:00:00

abstract：:Three children presented at birth with axial hypotonia and symmetrical flaccid paresis limited to the upper extremities, and involving proximal and distal muscle groups. At birth, palmar flexion creases were poorly developed, and the hand muscles were atrophic. These clinical features, the muscle biopsy findings, and ...

journal_title：Muscle & nerve

authors： Darwish H,Sarnat H,Archer C,Brownell K,Kotagal S

更新日期：1981-03-01 00:00:00

abstract：INTRODUCTION:The aim of this study was to describe the therapeutic effects of immunomodulatory therapy in 3 patients with childhood autoimmune necrotizing myopathy with anti-signal recognition particle antibodies (SRP-ANM). METHODS:Before treatment, data on clinical features, muscle pathology, and thigh MRIs were obta...

journal_title：Muscle & nerve

authors： Zhao Y,Liu X,Zhang W,Yuan Y

更新日期：2017-12-01 00:00:00

abstract：:To study noninvasively multiple descending volleys on alpha motoneurons, we used a 30-50% maximum H-reflex in the wrist flexor muscle conditioned by a subthreshold magnetic stimulus of the contralateral motor cortex as a parameter of motoneuronal excitability in seven neurologically healthy subjects. The time interval...

journal_title：Muscle & nerve

authors： van der Linden C,Bruggeman R

更新日期：1993-04-01 00:00:00

abstract：:The absolute number of satellite cells (SC) in young and adult rat skeletal muscle was estimated by correlating data from light and electron microscopic quantitation of myofiber nuclei (myonuclei and satellite cell nuclei) with biochemical assays for determining total muscle DNA content. Expressed both as a proportion...

journal_title：Muscle & nerve

authors： Gibson MC,Schultz E

更新日期：1983-10-01 00:00:00

abstract：INTRODUCTION:In this study we explore several methods for incorporating survival information in the analysis of Amyotrophic Lateral Sclerosis Functional Rating Scale (ALSFRS) scores. METHODS:ALSFRS scores and patient survival times were simulated based on estimates from a recent clinical trial. Six analysis approaches...

journal_title：Muscle & nerve

authors： Healy BC,Schoenfeld D

更新日期：2012-10-01 00:00:00

abstract：:We prospectively studied the diagnostic utility of upper limb segmental reflexes in patients with suspected cervical radiculopathy (CR). Fifty-three patients (29 men and 24 women), referred for electrodiagnostic testing, were positive for at least one of four clinical criteria for CR: abnormal (1) history, (2) motor (...

journal_title：Muscle & nerve

authors： Miller TA,Pardo R,Yaworski R

更新日期：1999-08-01 00:00:00

abstract：:The purpose of this study was to determine if chronic fatigue syndrome (CSF) is characterized by abnormalities in oxidative muscle metabolism. Patients with CFS according to Centers for Disease Control (CDC) criteria (n = 22) were compared to normal sedentary subjects (n = 15). CFS patients were also tested before and...

journal_title：Muscle & nerve

authors： McCully KK,Natelson BH,Iotti S,Sisto S,Leigh JS Jr

更新日期：1996-05-01 00:00:00

abstract：:We report two female patients with a history of alcohol abuse presenting with proximal painful muscle weakness following aversion therapy with emetine hydrochloride. Muscle biopsy of Case 1 showed a reversible floccular-shaped loss of myosin ATPase and dehydrogenase, an accumulation of PAS positive material, and a nor...

journal_title：Muscle & nerve

authors： Sugie H,Russin R,Verity MA

更新日期：1984-01-01 00:00:00

abstract：INTRODUCTION:The aim of this work was to determine the effect of chronic alcohol exposure on peripheral nerves in a nutritionally balanced rat model of alcoholism. METHODS:Three different strains of adult male rats were pair-fed for 8 weeks with isocaloric liquid diets containing 0% or 37% ethanol. Nerve conduction st...

journal_title：Muscle & nerve

authors： Mellion ML,Nguyen V,Tong M,Gilchrist J,De La Monte S

更新日期：2013-08-01 00:00:00

abstract：:Platelet-derived microparticle (PDMP) levels were measured using an enzyme-linked immunosorbent assay (ELISA) to elucidate the role of platelet activation in patients with polymyositis or dermatomyositis (PM/DM). PDMP levels in active PM/DM patients (median 13.3 U/ml, interquartile range 9.9-20.7 U/ml, n = 16) and tho...

journal_title：Muscle & nerve

authors： Shirafuji T,Hamaguchi H,Higuchi M,Kanda F

更新日期：2009-05-01 00:00:00

abstract：:We studied the effects of a 12-week progressive resistance strength training program in weakened muscles of 5 patients with sporadic inclusion body myositis (IBM). Strength was evaluated with Medical Research Council (MRC) scale ratings and quantitative isometric and dynamic tests. Changes in serum creatine kinase (CK...

journal_title：Muscle & nerve

authors： Spector SA,Lemmer JT,Koffman BM,Fleisher TA,Feuerstein IM,Hurley BF,Dalakas MC

更新日期：1997-10-01 00:00:00

abstract：:The electrical and mechanical properties of paralyzed human thenar muscles were measured in response to supramaximal stimulation of the median nerve in individuals with chronic cervical spinal cord injury. These data were compared to those recorded from control muscles. Spontaneous motor unit activity was common in pa...

journal_title：Muscle & nerve

authors： Thomas CK

更新日期：1997-07-01 00:00:00

abstract：INTRODUCTION:Evaluation of phrenic neuropathy (PN) with phrenic nerve conduction studies (PNCS) is associated with false negatives. Visualization of diaphragmatic muscle twitch with diaphragm ultrasound (DUS) when performing PNCS may help to solve this problem. METHODS:We performed bilateral, simultaneous DUS-PNCS in ...

journal_title：Muscle & nerve

authors： Johnson NE,Utz M,Patrick E,Rheinwald N,Downs M,Dilek N,Dogra V,Logigian EL

更新日期：2014-05-01 00:00:00

abstract：:We observed a marked prolongation of the transcranially evoked silent period during continuous intrathecal administration of high doses of the gamma-aminobutyric acid (GABA)B receptor agonist baclofen in a patient with generalized dystonia. Size of motor evoked potentials and central conduction time remained unchanged...

journal_title：Muscle & nerve

authors： Siebner HR,Dressnandt J,Auer C,Conrad B

更新日期：1998-09-01 00:00:00

abstract：:Epidemiological studies of the carpal tunnel syndrome have generally overlooked the possibility of a familial occurrence. A prospective study was undertaken to determine the prevalence and significance of a positive family history of carpal tunnel syndrome. Seventy-five of 253 women and 40 of 168 men with a confirmed ...

journal_title：Muscle & nerve

authors： Radecki P

更新日期：1994-03-01 00:00:00

abstract：:Muscle biopsy and computerized tomography indicated that unilateral enlargement of the gastrocnemius muscle in a 12-year-old girl was the result of an infiltrating lipoma. This rare condition may cause diagnostic confusion before EMG and muscle biopsy studies are performed, but it can be readily distinguished from oth...

journal_title：Muscle & nerve

authors： Fetell MR,Duffy PE,Rowland LP

更新日期：1978-01-01 00:00:00

abstract：INTRODUCTION:Neuromuscular activation can be influenced by both muscle temperature (Tm) and fatigue. METHODS:To assess the effects of Tm and fatigue on the electromechanical delay (EMD), 15 participants performed voluntary isometric contractions of different intensities under neutral (TmN), low (TmL), and high (TmH) T...

journal_title：Muscle & nerve

authors： Cè E,Rampichini S,Agnello L,Limonta E,Veicsteinas A,Esposito F

更新日期：2013-04-01 00:00:00

abstract：:The frequency of a recently described point mutation of the ciliary neurotrophic factor (CNTF) gene was investigated in a population of 154 German patients with motor neuron disease (MND). Twenty-two percent of the patients were heterozygous, 2% homozygous for the CNTF mutation. Since the gene defect is per se not lin...

journal_title：Muscle & nerve

authors： Giess R,Goetz R,Schrank B,Ochs G,Sendtner M,Toyka K

更新日期：1998-02-01 00:00:00

abstract：:Electrodiagnostic studies were analyzed in patients with neuropathy associated with IgM monoclonal proteins, 7 with anti-myelin associated glycoprotein reactivity (MAG) and 7 nonreactive to MAG. The findings were distinctly different in the two groups. The electrodiagnostic studies of all the MAG-reactive patients had...

journal_title：Muscle & nerve

authors： Kelly JJ Jr

更新日期：1990-12-01 00:00:00

abstract：INTRODUCTION:We studied neurodevelopmental and behavioral/emotional symptoms in patients with Duchenne muscular dystrophy (DMD). METHODS:Retrospective case series of neurodevelopmental and behavioral/emotional symptoms obtained through review of systems of 700 DMD patients in relation to dystrophin gene mutations. RE...

journal_title：Muscle & nerve

authors： Darmahkasih AJ,Rybalsky I,Tian C,Shellenbarger KC,Horn PS,Lambert JT,Wong BL

更新日期：2020-04-01 00:00:00

abstract：INTRODUCTION:Doppler ultrasonography (DU) has recently been shown to be useful in imaging carpal tunnel syndrome (CTS). In this study, we aim to characterize the changes seen after exercise and electrical stimulation. METHODS:Five patients with CTS were recruited with 5 age-matched subjects. DU was used to visualize t...

journal_title：Muscle & nerve

authors： Ng ES,Ng KW,Wilder-Smith EP

更新日期：2013-01-01 00:00:00

abstract：:Adult skeletal muscle fibers are among the few cell types that are truly multinucleated. Recently, evidence has accumulated supporting a role for the modulation of myonuclear number during muscle remodeling in response to injury, adaptation, and disease. These studies have demonstrated that muscle hypertrophy is assoc...

journal_title：Muscle & nerve

authors： Allen DL,Roy RR,Edgerton VR

更新日期：1999-10-01 00:00:00

abstract：:Six members originating from two families with hereditary motor and sensory neuropathy (hypertrophic and neuronal types) were noted to have enlarged calf muscles. Muscle computed tomography revealed that muscle enlargement in the propositus of the family with the hypertrophic type of HMSN was due to an increase in mus...

journal_title：Muscle & nerve

authors： De Visser M,Hoogendijk JE,Ongerboer BW,Verbeeten BJ Jr

更新日期：1990-01-01 00:00:00

abstract：:This study analyses maximum voluntary isometric contraction (MVIC) and its measurement by recording the force profile during maximal-effort, 7-s hand-grip contractions. Six healthy subjects each performed three trials repeated at short intervals to study variation from fatigue. These three trials were performed during...

journal_title：Muscle & nerve

authors： Househam E,McAuley J,Charles T,Lightfoot T,Swash M

更新日期：2004-03-01 00:00:00

abstract：:Multifocal motor neuropathy (MMN) is a chronic, immune-mediate, peripheral myelinopathy. Inherent in its name, MMN implies involvement of two or more motor nerves. We report three patients with weakness and partial motor conduction block restricted to a single nerve and localized to sites that are not at risk for entr...

journal_title：Muscle & nerve

authors： Felice KJ,Goldstein JM

更新日期：2002-05-01 00:00:00

abstract：:Peripheral neuropathy marked by reduced nerve conduction velocities was found in four unrelated children, between the ages of 15 months and 9 years, whose autopsies revealed Leigh's subacute necrotizing encephalomyelopathy. Sural nerve biopsies disclosed primary demyelination and remyelination, as well as loss of myel...

journal_title：Muscle & nerve

authors： Goebel HH,Bardosi A,Friede RL,Kohlschütter A,Albani M,Siemes H

更新日期：1986-02-01 00:00:00

abstract：:Mitochondrial trifunctional protein (TFP) deficiency is a rare disorder of the fatty acid beta-oxidation cycle with heterogeneous phenotypes and occurs secondary to either alpha- or beta-subunit mutations. We characterized the neuromyopathic phenotype of TFP deficiency through adolescence or adulthood in 11 patients, ...

journal_title：Muscle & nerve

authors： Spiekerkoetter U,Bennett MJ,Ben-Zeev B,Strauss AW,Tein I

更新日期：2004-01-01 00:00:00

abstract：:A 62-year-old woman with axonal Guillain-Barré syndrome developed weakness and urinary retention simultaneously. The retention failed to recover for 10 months even after she regained the ability to walk. The patient exhibited no postural hypotension. Videourodynamics showed that the retention was caused not by the bla...

journal_title：Muscle & nerve

authors： Sakakibara R,Uchiyama T,Tamura N,Kuwabara S,Asahina M,Hattori T

更新日期：2007-01-01 00:00:00