Association analysis between canine behavioural traits and genetic polymorphisms in the Shiba Inu breed.

Abstract:

:The relationships between behavioural trait data and the genotype of 15 polymorphisms in eight neurotransmitter-related genes were analysed in 77 dogs of the Shiba Inu breed, an indigenous Japanese dog. The data were obtained from a 26-item questionnaire on the dog's behaviour, distributed to the dog's owners, through veterinary hospitals and the Shiba Inu breed magazine. A factor analysis of the questionnaire items extracted eight factors accounting for 66.8% of the variance. An association analysis between these factors and genetic polymorphisms indicated that the polymorphism of c.471T>C in the solute carrier family 1 (neuronal/epithelial high-affinity glutamate transporter) member 2 (SLC1A2) gene was significantly associated with Factor 1, referred to as 'aggression to strangers'. This association remained stable in separate analyses of data from surveys obtained from the hospitals and those obtained from the magazine. The results suggest that the c.471T>C polymorphism is associated with some types of aggressive behaviour in the Shiba Inu. Further studies using other dog breeds are necessary to extend these findings to dogs in general.

journal_name

Anim Genet

journal_title

Animal genetics

authors

Takeuchi Y,Kaneko F,Hashizume C,Masuda K,Ogata N,Maki T,Inoue-Murayama M,Hart BL,Mori Y

doi

10.1111/j.1365-2052.2009.01888.x

subject

Has Abstract

pub_date

2009-10-01 00:00:00

pages

616-22

issue

5

eissn

0268-9146

issn

1365-2052

pii

AGE1888

journal_volume

40

pub_type

杂志文章
  • Chromosomal assignment of chicken clone contigs by extending the consensus linkage map.

    abstract::The bacterial artificial clone-based physical map for chicken plays an important role in the integration of the consensus linkage map and the whole-genome shotgun sequence. It also provides a valuable resource for clone selection within applications such as fluorescent in situ hybridization and positional cloning. How...

    journal_title:Animal genetics

    pub_type: 杂志文章

    doi:10.1111/j.1365-2052.2005.01289.x

    authors: Aerts JA,Veenendaal T,van der Poel JJ,Crooijmans RP,Groenen MA

    更新日期:2005-06-01 00:00:00

  • Novel alternative splicing by exon skipping in KIT associated with whole-body roan in an intercrossed population of Landrace and Korean Native pigs.

    abstract::The KIT locus has been suggested to be a strong candidate region linked with whole-body roan in the F(2) population produced by intercrosses between Landrace and Korean Native pigs. In this manuscript, we report the finding of a novel alternative splicing event in the porcine KIT gene that results in the skipping of e...

    journal_title:Animal genetics

    pub_type: 杂志文章

    doi:10.1111/j.1365-2052.2011.02225.x

    authors: Lim HT,Zhong T,Cho IC,Seo BY,Kim JH,Lee SS,Ko MS,Park HB,Kim BW,Lee JH,Jeon JT

    更新日期:2011-08-01 00:00:00

  • Transcriptomic analysis reveals differentially expressed genes associated with wool length in rabbit.

    abstract::Rabbit fur characteristics are primarily genetically determined traits. We used Illumina high-throughput sequencing technology to assess gene expression in the skin tissues of rabbits derived from a cross between Wanxi Angora rabbits and Rex rabbits, which exhibit differential characteristics of short and long wool re...

    journal_title:Animal genetics

    pub_type: 杂志文章

    doi:10.1111/age.12701

    authors: Zhao B,Chen Y,Hao Y,Yang N,Wang M,Mei M,Wang J,Qiu X,Wu X

    更新日期:2018-10-01 00:00:00

  • Current knowledge of microRNA characterization in agricultural animals.

    abstract::MicroRNA (miRNA) is a class of single-stranded small (19-24nt) regulatory RNA that silences gene expression post-transcriptionally. miRNAs regulate a wide range of biological processes through the recognition of complementary sequences between miRNAs and their target genes. Profiling studies in livestock have revealed...

    journal_title:Animal genetics

    pub_type: 杂志文章,评审

    doi:10.1111/j.1365-2052.2009.01995.x

    authors: Liu HC,Hicks JA,Trakooljul N,Zhao SH

    更新日期:2010-06-01 00:00:00

  • Genomic prediction of reproduction traits for Merino sheep.

    abstract::Economically important reproduction traits in sheep, such as number of lambs weaned and litter size, are expressed only in females and later in life after most selection decisions are made, which makes them ideal candidates for genomic selection. Accurate genomic predictions would lead to greater genetic gain for thes...

    journal_title:Animal genetics

    pub_type: 杂志文章

    doi:10.1111/age.12541

    authors: Bolormaa S,Brown DJ,Swan AA,van der Werf JHJ,Hayes BJ,Daetwyler HD

    更新日期:2017-06-01 00:00:00

  • Recombination rates and gene order for some serum alpha-protease inhibitors and immunoglobulin heavy-chain allotypes in pigs.

    abstract::Linkage analysis between the genes coding for immunoglobulin heavy-chain allotypes and variants of some serum alpha-protease inhibitors produced lod scores above the significance limit of 3. The maximum likelihood estimate of the recombination fraction (theta) ranged from 0.15 to 0.20. Since this is the second report ...

    journal_title:Animal genetics

    pub_type: 杂志文章

    doi:10.1111/j.1365-2052.1987.tb00779.x

    authors: Vögeli P,Kühne R,Wysshaar M,Stranzinger G

    更新日期:1987-01-01 00:00:00

  • Genome-wide association study identifies markers associated with carcass and meat quality traits in Italian Large White pigs.

    abstract::A GWAS was performed using the genotypes obtained by PorcineSNP60 v2 BeadChip and 11 phenotypic traits (carcass lean meat percentage; backfat thickness; Longissimus thoracis muscle thickness; lightness; backfat thickness measured with caliper at the midline; meat pH measured at about 1 h post mortem and 24 h post mort...

    journal_title:Animal genetics

    pub_type: 杂志文章

    doi:10.1111/age.13013

    authors: Fabbri MC,Zappaterra M,Davoli R,Zambonelli P

    更新日期:2020-12-01 00:00:00

  • On measures of association among genetic variables.

    abstract::Systems involving many variables are important in population and quantitative genetics, for example, in multi-trait prediction of breeding values and in exploration of multi-locus associations. We studied departures of the joint distribution of sets of genetic variables from independence. New measures of association b...

    journal_title:Animal genetics

    pub_type: 杂志文章

    doi:10.1111/j.1365-2052.2012.02326.x

    authors: Gianola D,Manfredi E,Simianer H

    更新日期:2012-07-01 00:00:00

  • The albinism of the feral Asinara white donkeys (Equus asinus) is determined by a missense mutation in a highly conserved position of the tyrosinase (TYR) gene deduced protein.

    abstract::A feral donkey population (Equus asinus), living in the Asinara National Park (an island north-west of Sardinia, Italy), includes a unique white albino donkey subpopulation or colour morph that is a major attraction of this park. Disrupting mutations in the tyrosinase (TYR) gene are known to cause recessive albinisms ...

    journal_title:Animal genetics

    pub_type: 杂志文章

    doi:10.1111/age.12386

    authors: Utzeri VJ,Bertolini F,Ribani A,Schiavo G,Dall'Olio S,Fontanesi L

    更新日期:2016-02-01 00:00:00

  • Estimations of the efficacy and reliability of paternity assignments from DNA microsatellite analysis of multiple-sire matings.

    abstract::It is important for bovine DNA testing laboratories to provide the cattle industry with accurate estimates of the efficacy and reliability of DNA tests offered so that end users of this technology can adequately assess the cost-benefits of testing. To address these issues for bovine paternity testing, paternity exclus...

    journal_title:Animal genetics

    pub_type: 杂志文章

    doi:10.1046/j.1365-2052.1999.00511.x

    authors: Vankan DM,Faddy MJ

    更新日期:1999-10-01 00:00:00

  • Genome-wide association study of milk production traits in a crossbred dairy sheep population using three statistical models.

    abstract::Milk production is one of the most important characteristics of dairy sheep, and the identification of genes affecting milk production traits is critical to understanding the genetics and improve milk production in future generations. Three statistical techniques, namely GWAS, ridge-regression BLUP and BayesC ...

    journal_title:Animal genetics

    pub_type: 杂志文章

    doi:10.1111/age.12956

    authors: Li H,Wu XL,Tait RG Jr,Bauck S,Thomas DL,Murphy TW,Rosa GJM

    更新日期:2020-08-01 00:00:00

  • Genetic mapping of quantitative trait loci for meat quality and muscle metabolic traits in cattle.

    abstract::A whole-genome scan was carried out in New Zealand and Australia to detect quantitative trait loci (QTL) for live animal and carcass composition traits and meat quality attributes in cattle. Backcross calves (385 heifers and 398 steers) were generated, with Jersey and Limousin backgrounds. The New Zealand cattle were ...

    journal_title:Animal genetics

    pub_type: 杂志文章

    doi:10.1111/j.1365-2052.2011.02197.x

    authors: Esmailizadeh AK,Morris CA,Cullen NG,Kruk ZA,Lines DS,Hickey SM,Dobbie PM,Bottema CD,Pitchford WS

    更新日期:2011-12-01 00:00:00

  • Farm-by-farm analysis of microsatellite, mtDNA and SNP genotype data reveals inbreeding and crossbreeding as threats to the survival of a native Spanish pig breed.

    abstract::The Chato Murciano (CM), a pig breed from the Murcia region in the southeastern region of Spain, is a good model for endangered livestock populations. The remaining populations are bred on approximately 15 small farms, and no herdbook exists. To assess the genetic threats to the integrity and survival of the CM breed,...

    journal_title:Animal genetics

    pub_type: 杂志文章

    doi:10.1111/age.12001

    authors: Herrero-Medrano JM,Megens HJ,Crooijmans RP,Abellaneda JM,Ramis G

    更新日期:2013-06-01 00:00:00

  • Pronounced differences in the frequency of TaqI beta A-inhibin alleles between sheep breeds with different reproductive performance.

    abstract::A total of 419 individuals of four breeds with differing fecundity (Rhoenschaf, Merinolandschaf, East Friesian Milksheep, Romanov) and several wild sheep of the Ovis musimon, O. orientalis, O. vignei and O. ammon groups were screened for genetic variation at the beta A-inhibin (INHBA) locus with up to 11 enzymes. The ...

    journal_title:Animal genetics

    pub_type: 杂志文章

    doi:

    authors: Leyhe B,Hiendleder S,Jaeger C,Wassmuth R

    更新日期:1994-02-01 00:00:00

  • Altered expression of CYP17A1 and CYP19A1 in undescended testes of dogs with unilateral cryptorchidism.

    abstract::Cryptorchidism is the most common disorder of sex development in dogs and testosterone plays a crucial role in the inguinal phase of the testes descending into the scrotum. The molecular background of impaired testosterone synthesis in the testes of cryptorchid dogs is poorly elucidated. In this study, we analyzed the...

    journal_title:Animal genetics

    pub_type: 杂志文章

    doi:10.1111/age.12977

    authors: Krzeminska P,Stachowiak M,Skrzypski M,Nowak T,Maslak A,Switonski M

    更新日期:2020-10-01 00:00:00

  • Fine mapping of porcine SSC14 QTL and SCD gene effects on fatty acid composition and melting point of fat in a Duroc purebred population.

    abstract::The stearoyl-CoA desaturase (delta-9-desaturase; SCD) gene is a candidate gene for fatty acid composition. It is located on pig SSC14 in a region where quantitative trait loci (QTL) for fatty acid composition were previously detected in a Duroc purebred population. The objective of the present study was to fine map th...

    journal_title:Animal genetics

    pub_type: 杂志文章

    doi:10.1111/j.1365-2052.2011.02236.x

    authors: Uemoto Y,Nakano H,Kikuchi T,Sato S,Ishida M,Shibata T,Kadowaki H,Kobayashi E,Suzuki K

    更新日期:2012-04-01 00:00:00

  • Evidence for pleiotropism and recent selection in the PLAG1 region in Australian Beef cattle.

    abstract::A putative functional mutation (rs109231213) near PLAG1 (BTA14) associated with stature was studied in beef cattle. Data from 8199 Bos taurus, Bos indicus and Tropical Composite cattle were used to test the associations between rs109231213 and various phenotypes. Further, 23 496 SNPs located on BTA14 were tested for a...

    journal_title:Animal genetics

    pub_type: 杂志文章

    doi:10.1111/age.12075

    authors: Fortes MR,Kemper K,Sasazaki S,Reverter A,Pryce JE,Barendse W,Bunch R,McCulloch R,Harrison B,Bolormaa S,Zhang YD,Hawken RJ,Goddard ME,Lehnert SA

    更新日期:2013-12-01 00:00:00

  • Effects of DGAT1 and GHR on milk yield and milk composition in the Chinese dairy population.

    abstract::Previous studies have demonstrated that the p.Lys232Ala substitution in the acylCoA: diacylglycerol acyltransferase (DGAT1) gene and the p.Phe279Tyr mutation in the growth hormone receptor (GHR) gene are the causative quantitative trait loci underlying milk yield and composition on BTA14 and BTA20 respectively. To exa...

    journal_title:Animal genetics

    pub_type: 杂志文章

    doi:10.1111/j.1365-2052.2009.01945.x

    authors: Sun D,Jia J,Ma Y,Zhang Y,Wang Y,Yu Y,Zhang Y

    更新日期:2009-12-01 00:00:00

  • Quantitative trait loci for chemical body composition traits in pigs and their positional associations with body tissues, growth and feed intake.

    abstract::In this study, quantitative trait loci (QTL) for chemical and physical body composition, growth and feed intake in pigs were identified in a three-generation full-sib population, developed by crossing Pietrain sires with a commercial dam line. Phenotypic data from 315 F(2) animals were available for protein and lipid ...

    journal_title:Animal genetics

    pub_type: 杂志文章

    doi:10.1111/j.1365-2052.2007.01689.x

    authors: Duthie C,Simm G,Doeschl-Wilson A,Kalm E,Knap PW,Roehe R

    更新日期:2008-04-01 00:00:00

  • Comparative porcine gene mapping relative to human chromosomes 9, 10, 20 and 22.

    abstract::Comparative anchor tagged sequence (CATS) consensus primers from loci mapped to human chromosomes 9, 10, 20, and 22 have been used to amplify homologous loci in pigs. Of 53, CATS primers tested in pigs, only 23 yielded products homologous to the human locus (42% success). Ten loci were physically mapped (43% success r...

    journal_title:Animal genetics

    pub_type: 杂志文章

    doi:10.1046/j.1365-2052.2001.00787.x

    authors: Lee JH,Zhang W,Moran C

    更新日期:2001-10-01 00:00:00

  • Associations of GH gene variants with performance traits in F2 generations of European wild boar, Piétrain and Meishan pigs.

    abstract::The role of the porcine GH gene was investigated in 292 F2 animals of mating Wild Boar x Piétrain and in 310 F2 animals of mating Meishan x Piétrain. Forty-three traits of fattening, carcass composition, meat quality and stress resistance were recorded. For the analysis of associations between GH gene variants and qua...

    journal_title:Animal genetics

    pub_type: 杂志文章

    doi:10.1111/j.1365-2052.1997.00093.x

    authors: Knorr C,Moser G,Müller E,Geldermann H

    更新日期:1997-04-01 00:00:00

  • Heritability of racing performance in the Australian Thoroughbred racing population.

    abstract::Performance data for 164,046 Thoroughbreds entered in a race or official barrier trial in Australia were provided by Racing Information Services Australia. Analyses estimating the heritability for a range of racing performance traits using a single-trait animal model were performed using ASREML-R. Log of cumulative ea...

    journal_title:Animal genetics

    pub_type: 杂志文章

    doi:10.1111/age.12234

    authors: Velie BD,Hamilton NA,Wade CM

    更新日期:2015-02-01 00:00:00

  • An advanced sheep (Ovis aries, 2n = 54) cytogenetic map and assignment of 88 new autosomal loci by fluorescence in situ hybridization and R-banding.

    abstract::Presented herein is an updated sheep cytogenetic map that contains 452 loci (291 type I and 161 type II) assigned to specific chromosome bands or regions on standard R-banded ideograms. This map, which significantly extends our knowledge of the physical organization of the ovine genome, includes new assignments for 88...

    journal_title:Animal genetics

    pub_type: 杂志文章

    doi:10.1111/j.1365-2052.2007.01598.x

    authors: Di Meo GP,Perucatti A,Floriot S,Hayes H,Schibler L,Rullo R,Incarnato D,Ferretti L,Cockett N,Cribiu E,Williams JL,Eggen A,Iannuzzi L

    更新日期:2007-06-01 00:00:00

  • T lymphocyte development and maturation in horses.

    abstract::Monoclonal antibodies specific for equine T lymphocyte subpopulations were produced and procedures for the continuous culture of equine lymphocytes were developed. These reagents and procedures were used to analyse the appearance, maturation and functions of T lymphocytes in normal horses and in T lymphocyte deficient...

    journal_title:Animal genetics

    pub_type: 杂志文章,评审

    doi:10.1111/j.1365-2052.1988.tb00825.x

    authors: Perryman LE,Wyatt CR,Magnuson NS,Mason PH

    更新日期:1988-01-01 00:00:00

  • A single-base change in the tyrosine kinase II domain of ovine FGFR3 causes hereditary chondrodysplasia in sheep.

    abstract::Ovine hereditary chondrodysplasia, or spider lamb syndrome (SLS), is a genetic disorder that is characterized by severe skeletal abnormalities and has resulted in substantial economic losses for sheep producers. Here we demonstrate that a non-synonymous T>A transversion in the highly conserved tyrosine kinase II domai...

    journal_title:Animal genetics

    pub_type: 杂志文章

    doi:10.1111/j.1365-2052.2005.01398.x

    authors: Beever JE,Smit MA,Meyers SN,Hadfield TS,Bottema C,Albretsen J,Cockett NE

    更新日期:2006-02-01 00:00:00

  • Differences in the DNA restriction patterns between sheep with HbA and HbB.

    abstract::DNA samples obtained from sheep homozygous for HbA, for HbB and heterozygous were subjected to Southern blot analysis using a goat beta F and a rabbit beta 1-globin gene as probes. Sheep homozygous for HbA show a different restriction pattern from that of sheep homozygous for HbB with each of the used endonucleases. T...

    journal_title:Animal genetics

    pub_type: 杂志文章

    doi:10.1111/j.1365-2052.1987.tb00764.x

    authors: Di Gregorio P,Rando A,Masina P

    更新日期:1987-01-01 00:00:00

  • A third variant of glucose phosphate isomerase in pigs.

    abstract::A new variant of glucose phosphate isomerase (GPI), also known as phosphohexose isomerase (PHI), was detected in a primitive pig population. ...

    journal_title:Animal genetics

    pub_type: 杂志文章

    doi:10.1111/j.1365-2052.1988.tb00790.x

    authors: Van de Weghe A,Yablanski T,Van Zeveren A,Bouquet Y

    更新日期:1988-01-01 00:00:00

  • Genetic diversity within chicken populations from different continents and management histories.

    abstract::Intra-population variation was assessed in 1970 chickens from 64 populations using 29 autosomal microsatellites. On average, 95% of the loci were polymorphic across populations. In 1456 (c. 83%) of the 1763 combinations of populations and polymorphic loci, no departure from Hardy-Weinberg equilibrium was observed. On ...

    journal_title:Animal genetics

    pub_type: 杂志文章

    doi:10.1111/j.1365-2052.2007.01650.x

    authors: Granevitze Z,Hillel J,Chen GH,Cuc NT,Feldman M,Eding H,Weigend S

    更新日期:2007-12-01 00:00:00

  • Identification of contemporary selection signatures using composite log likelihood and their associations with marbling score in Korean cattle.

    abstract::Positive selection not only increases beneficial allele frequency but also causes augmentation of allele frequencies of sequence variants in close proximity. Signals for positive selection were detected by the statistical differences in subsequent allele frequencies. To identify selection signatures in Korean cattle, ...

    journal_title:Animal genetics

    pub_type: 杂志文章

    doi:10.1111/age.12209

    authors: Ryu J,Lee C

    更新日期:2014-12-01 00:00:00

  • Contributions of Portuguese cattle breeds to genetic diversity using marker-estimated kinships.

    abstract::The quantitative assessment of genetic diversity within and between populations is important for decision-making in genetic conservation plans. In our study, we applied the livestock core set method to define the contribution of 15 cattle breeds, 11 of which are Portuguese indigenous cattle breeds, to genetic diversit...

    journal_title:Animal genetics

    pub_type: 杂志文章

    doi:10.1111/j.1365-2052.2004.01168.x

    authors: Mateus JC,Eding H,Penedo MC,Rangel-Figueiredo MT

    更新日期:2004-08-01 00:00:00