Variation in measures of urea kinetics over four years in a single adult.

Abstract:

:Urea kinetics was measured in a single woman on five occasions over four years by the prime/intermittent oral-dose method with [15N15N]-urea. On a nitrogen intake of 231 +/- 24 mg/kg/day, urea production was 198 +/- 22 mg/kg/day, with the urinary excretion of urea being 143 +/- 25 mg/kg/day. Urea hydrolysis and salvaging in the bowel was 55 +/- 6 mgN/kg/day. The coefficients of variation for production, 11 per cent, excretion, 18 per cent, and hydrolysis, 11 per cent, were similar to that for intake, 10 per cent, and substantially less than reported inter-individual variations from other studies. It is concluded that the method employed for measuring urea kinetics gives reproducible results and that the intra-individual variation in urea kinetics is much less than the inter-individual variation.

journal_name

Eur J Clin Nutr

authors

Hibbert JM,Jackson AA

subject

Has Abstract

pub_date

1991-07-01 00:00:00

pages

347-51

issue

7

eissn

0954-3007

issn

1476-5640

journal_volume

45

pub_type

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