Osteoclastlike giant cell tumor of the salivary gland.

Abstract:

:Giant cell tumor of the salivary gland is extremely rare, with only 15 cases published in the English literature. The tumor characteristically contains a mixture of multinucleated giant cells, resembling osteoclasts of bone, and neoplastic mononuclear cells. In about half of the reported cases, there is an associated carcinomatous component. We are reporting an additional case of giant cell tumor of the parotid gland that was initially misinterpreted as an extraosseous osteosarcoma in the biopsy specimen. The histologic and immunohistochemical findings as well as a review of the literature with discussion of the histogenesis of this unusual neoplasm are presented.

journal_name

Ann Diagn Pathol

authors

Fang X,Hicks DG,Hicks W Jr,Zhang S

doi

10.1016/j.anndiagpath.2007.06.009

subject

Has Abstract

pub_date

2009-04-01 00:00:00

pages

114-8

issue

2

eissn

1092-9134

issn

1532-8198

pii

S1092-9134(07)00102-5

journal_volume

13

pub_type

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