Abstract:
:Primary rhabdomyosarcoma of salivary glands is an extremely rare neoplasm, mostly seen in children. A newly described subtype of rhabdomyosarcoma, sclerosing rhabdomyosarcoma, has not yet been reported in this location. We report on a parotid gland tumor characterized by infiltrative growth of primitive type of neoplastic cells showing strong and diffuse nuclear positivity for MyoD1 and myogenin and by prominent hyalinized/chondroid matrix with some myxoid foci. The tumor recurred several times, and in recurrent tumors, differentiation into strap myoid cells appeared. There were no distant metastases during the 5-year follow-up. Sclerosing rhabdomyosarcoma may cause differential diagnostic problems because it could be confounded for osteosarcoma, chondrosarcoma, and some other types of sarcoma, and as in our case, for myxofibrosarcoma and myoepithelial carcinoma. Its location in the head and neck is of special interest because 6 of 14 previously described adult cases of sclerosing rhabdomyosarcoma and 7 of 18 pediatric cases also occurred in this region. To our knowledge, this is the first reported case of primary sclerosing rhabdomyosarcoma of the parotid gland.
journal_name
Ann Diagn Patholjournal_title
Annals of diagnostic pathologyauthors
Lamovec J,Volavsek Mdoi
10.1016/j.anndiagpath.2009.02.002subject
Has Abstractpub_date
2009-10-01 00:00:00pages
334-8issue
5eissn
1092-9134issn
1532-8198pii
S1092-9134(09)00003-3journal_volume
13pub_type
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journal_title:Annals of diagnostic pathology
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journal_title:Annals of diagnostic pathology
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journal_title:Annals of diagnostic pathology
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journal_title:Annals of diagnostic pathology
pub_type: 杂志文章
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journal_title:Annals of diagnostic pathology
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journal_title:Annals of diagnostic pathology
pub_type: 杂志文章
doi:10.1016/j.anndiagpath.2009.05.006
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journal_title:Annals of diagnostic pathology
pub_type: 杂志文章
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journal_title:Annals of diagnostic pathology
pub_type: 杂志文章
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journal_title:Annals of diagnostic pathology
pub_type: 杂志文章
doi:10.1053/adpa.2002.30607
更新日期:2002-02-01 00:00:00
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journal_title:Annals of diagnostic pathology
pub_type: 杂志文章
doi:10.1016/j.anndiagpath.2016.05.002
更新日期:2016-08-01 00:00:00
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journal_title:Annals of diagnostic pathology
pub_type: 杂志文章
doi:10.1016/j.anndiagpath.2004.12.010
更新日期:2005-04-01 00:00:00
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journal_title:Annals of diagnostic pathology
pub_type: 杂志文章
doi:10.1016/j.anndiagpath.2007.05.004
更新日期:2008-12-01 00:00:00
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journal_title:Annals of diagnostic pathology
pub_type: 杂志文章
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更新日期:2019-08-01 00:00:00
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journal_title:Annals of diagnostic pathology
pub_type: 杂志文章,评审
doi:10.1016/j.anndiagpath.2017.10.004
更新日期:2018-02-01 00:00:00
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journal_title:Annals of diagnostic pathology
pub_type: 杂志文章
doi:10.1016/j.anndiagpath.2006.03.003
更新日期:2006-12-01 00:00:00
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journal_title:Annals of diagnostic pathology
pub_type: 杂志文章
doi:10.1016/s1092-9134(97)80003-2
更新日期:1997-10-01 00:00:00
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journal_title:Annals of diagnostic pathology
pub_type: 杂志文章
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journal_title:Annals of diagnostic pathology
pub_type: 杂志文章
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journal_title:Annals of diagnostic pathology
pub_type: 杂志文章
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journal_title:Annals of diagnostic pathology
pub_type: 杂志文章
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journal_title:Annals of diagnostic pathology
pub_type: 杂志文章
doi:10.1016/j.anndiagpath.2011.06.003
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journal_title:Annals of diagnostic pathology
pub_type: 杂志文章
doi:10.1016/j.anndiagpath.2010.06.008
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journal_title:Annals of diagnostic pathology
pub_type: 杂志文章
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更新日期:2012-04-01 00:00:00
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journal_title:Annals of diagnostic pathology
pub_type: 杂志文章,评审
doi:10.1016/j.anndiagpath.2017.11.003
更新日期:2018-04-01 00:00:00
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journal_title:Annals of diagnostic pathology
pub_type: 杂志文章
doi:10.1016/j.anndiagpath.2005.07.012
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journal_title:Annals of diagnostic pathology
pub_type: 杂志文章,评审
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更新日期:2013-12-01 00:00:00
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journal_title:Annals of diagnostic pathology
pub_type: 杂志文章
doi:10.1016/s1092-9134(98)80032-4
更新日期:1998-02-01 00:00:00
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journal_title:Annals of diagnostic pathology
pub_type: 杂志文章
doi:10.1016/j.anndiagpath.2020.151593
更新日期:2020-10-01 00:00:00