Lactoferrin immuno-expression in human normal and neoplastic bone tissue.

abstract：:Vertebral fracture (VFx) is associated with various co-morbidities and increased mortality. In this paper, we have studied the detective value of height loss for VFx using two indices; historical height loss (HHL) which is the difference between the maximal height, and the current height (CH), and CH/knee height (KH) ...

journal_title：Journal of bone and mineral metabolism

authors： Yoh K,Kuwabara A,Tanaka K

更新日期：2014-09-01 00:00:00

abstract：:Secondary hyperparathyroidism (SHPT) develops as a compensatory mechanism when the body is in calcium deficit. SHPT may be harmful and has been associated with elevated blood pressure. The cause of SHPT could be low calcium intake, reduced intestinal calcium absorption, or increased excretion. However, the relative im...

journal_title：Journal of bone and mineral metabolism

authors： Saleh F,Jorde R,Sundsfjord J,Haug E,Figenschau Y

更新日期：2006-01-01 00:00:00

abstract：:Previously, we reported that millimeter wave promoted the chondrocyte proliferation by pushing cell cycle progression. Activation of K(+) channels plays an essential role in the stimulating of extracellular matrix (ECM) synthesis and the cell proliferation in chondrocytes. While it is unclear if millimeter wave enhanc...

journal_title：Journal of bone and mineral metabolism

authors： Li X,Liu C,Liang W,Ye H,Chen W,Lin R,Li Z,Liu X,Wu M

更新日期：2014-07-01 00:00:00

abstract：INTRODUCTION:Cold intolerance is defined as abnormal pain resulting from exposure to cold stimulation after trauma. However, the pathophysiology remains unclear. We recently demonstrated that regional osteoporotic changes accompanied by high bone turnover were involved in causing pain-like behaviors in the unloaded hin...

journal_title：Journal of bone and mineral metabolism

authors： Ibe K,Iba K,Hanaka M,Kiyomoto K,Hayakawa H,Teramoto A,Emori M,Yamashita T

更新日期：2020-07-01 00:00:00

abstract：:The aim of our study was to investigate the occurrence of osteonecrosis of the jaw (ONJ) after implementation of dental preventive measures before starting bisphosphonates (BPs) therapy and during treatment. All consecutive patients with bone lesions eligible for BPs treatment were prospectively evaluated. Before star...

journal_title：Journal of bone and mineral metabolism

authors： Bramati A,Girelli S,Farina G,Dazzani MC,Torri V,Moretti A,Piva S,Dimaiuta M,La Verde N

更新日期：2015-01-01 00:00:00

abstract：:McCune-Albright syndrome (MAS) is sometimes complicated by hypophosphatemia. However, it remains unclear whether a humoral factor is associated with the cause of hypophosphatemia. We isolated cells with mutations of the Gsalpha gene from fibrous bone dysplasia tissues of two MAS patients (MAS cells). Severe combined i...

journal_title：Journal of bone and mineral metabolism

authors： Yamamoto T,Miyamoto KI,Ozono K,Taketani Y,Katai K,Miyauchi A,Shima M,Yoshikawa H,Yoh K,Takeda E,Okada S

更新日期：2001-01-01 00:00:00

abstract：:In this study, we focused on collagen metabolism as a factor involved in menatetrenone (MK-4)-related improvement in bone quality. Using rats with a congenital ascorbic acid (AA) deficiency, osteogenic disorder Shionogi (ODS) rats, we established a model in which abnormal collagen metabolism reduced bone mechanical pr...

journal_title：Journal of bone and mineral metabolism

authors： Hara K,Akiyama Y

更新日期：2009-01-01 00:00:00

abstract：:Fourier transform infrared spectroscopy and 31P solid-state nuclear magnetic resonance spectroscopy were used to determine if any structural or compositional differences in osteogenesis imperfecta (OI) bone mineral could be detected that might help to explain the bone fragility observed in this disease. A previous stu...

journal_title：Journal of bone and mineral metabolism

authors： Cassella JP,Barrie PJ,Garrington N,Ali SY

更新日期：2000-01-01 00:00:00

abstract：:Based on the relationship between bone strength, trabecular skeletal structure, and bone mineral density (BMD), structure parameters for assessing vertebral bone strength were studied using 18 cancellous bone blocks from the third lumbar vertebra of elderly persons. The trabecular bone pattern of each bone block was b...

journal_title：Journal of bone and mineral metabolism

authors： Tanaka T,Sakurai T,Kashima I

更新日期：2001-01-01 00:00:00

abstract：:Simvastatin has been shown to stimulate osteogenesis both in vitro and in vivo. However, the mechanism by which simvastatin exerts its effects is still unclear. We previously reported that simvastatin promotes bone morphogenetic protein 2 (BMP-2) expression, induces osteoblastic differentiation, and inhibits adipocyti...

journal_title：Journal of bone and mineral metabolism

authors： Song C,Wang J,Song Q,Li X,Chen Z,Ma Q,Liu Z,Jia H,Dang G

更新日期：2008-01-01 00:00:00

abstract：:We evaluated short-term changes in serum amino-terminal procollagen propeptide (P1NP) and cross-linked C-terminal telopeptide (betaCTX) of type I collagen after parathyroidectomy (PTX) in 41 postmenopausal women with primary hyperparathyroidism (PHPT). Serum levels of 25-hydroxyvitamin D, intact PTH, calcium, phosphat...

journal_title：Journal of bone and mineral metabolism

authors： Boudou P,Ibrahim F,Cormier C,Sarfati E,Souberbielle JC

更新日期：2009-01-01 00:00:00

abstract：:Bone mineral density (BMD) seems not to be decreased in young patients given long-term suppressive doses of levothyroxine (LT4), but information regarding the bone microstructure in these patients is lacking. The aim of this study was to determine whether supraphysiologic doses of LT4, initiated during childhood or ad...

journal_title：Journal of bone and mineral metabolism

authors： Mendonça Monteiro de Barros G,Madeira M,Vieira Neto L,de Paula Paranhos Neto F,Carvalho Mendonça LM,Corrêa Barbosa Lima I,Corbo R,Fleiuss Farias ML

更新日期：2016-07-01 00:00:00

abstract：:Endoplasmic reticulum (ER) stress has been reported to be linked to various diseases such as diabetes, neurodegenerative diseases, and osteogenesis imperfecta (OI). Old astrocyte specifically induced substance (OASIS), a novel type of ER stress transducer, is a basic leucine zipper transcription factor belonging to th...

journal_title：Journal of bone and mineral metabolism

authors： Sekiya H,Murakami T,Saito A,Hino S,Tsumagari K,Ochiai K,Imaizumi K

更新日期：2010-07-01 00:00:00

abstract：:Hypophosphatasia is a rare inherited disorder characterized by a low serum alkaline phosphatase (ALP) activity and defective bone mineralization. Adult hypophosphatasia typically manifests in middle-age as a result of osteomalacia with recurrent stress fractures of the lower limb. However, considerable variation occur...

journal_title：Journal of bone and mineral metabolism

authors： Iida K,Fukushi J,Fujiwara T,Oda Y,Iwamoto Y

更新日期：2012-11-01 00:00:00

abstract：:The objective of this study was to record the clinical course of osteoporosis over time in Japanese women. We hypothesized that successful control of acute pain associated with osteoporosis will allow better treatment for health-related problems. To confirm this working hypothesis, we developed the Japan Questionnaire...

journal_title：Journal of bone and mineral metabolism

authors： Doi T,Akai M,Endo N,Fujino K,Iwaya T

更新日期：2013-11-01 00:00:00

abstract：:Skull changes are poorly described in vitamin D insufficiency [serum 25-hydroxyvitamin D (s-25(OH)D) 25-50 nmol/L]. We aimed to investigate factors associated with cranial anthropometrics in infants, especially s-25(OH)D. In infants 2.5-6 months old from the Odense Child Cohort, associations between cord and pregnancy...

journal_title：Journal of bone and mineral metabolism

authors： Egge S,Christensen N,Lykkedegn S,Jensen TK,Christesen HT

更新日期：2018-11-01 00:00:00

abstract：:The aim of the study was to assess body composition in subjects with phenylketonuria (PKU). Forty-five patients aged 13.8 ± 5.2 years were evaluated. Among them, 15 patients had not reached sexual maturity, showing normal serum values of phenylalanine (Phe) (subgroup 1), and 30 subjects were sexually mature (Tanner 5 ...

journal_title：Journal of bone and mineral metabolism

authors： Adamczyk P,Morawiec-Knysak A,Płudowski P,Banaszak B,Karpe J,Pluskiewicz W

更新日期：2011-03-01 00:00:00

abstract：:Osteoporosis is a growing health problem in women and in men. This cross-sectional study examined the association of anthropometric, lifestyle, and hormonal factors with bone mineral density (BMD) in 152 healthy Korean middle-aged men. Smoking habits and alcohol consumption were assessed by interview. Serum testostero...

journal_title：Journal of bone and mineral metabolism

authors： Rhee EJ,Oh KW,Lee WY,Kim SW,Oh ES,Baek KH,Kang MI,Park CY,Choi MG,Yoo HJ,Park SW

更新日期：2004-01-01 00:00:00

abstract：:The exact mechanism by which focal adhesion kinase (FAK) translates mechanical signals into osteogenesis differentiation in force-subjected cells has not been elucidated. The responses to different forces differ according to the origin of cells and the type of stress applied. Therefore, the recruitment of osteoclast a...

journal_title：Journal of bone and mineral metabolism

authors： Chen YJ,Shie MY,Hung CJ,Wu BC,Liu SL,Huang TH,Kao CT

更新日期：2014-11-01 00:00:00

abstract：INTRODUCTION:Data is currently lacking regarding association between the cholecystectomy/hepatectomy/pancreatectomy and the development of osteoporotic fracture. A retrospective cohort study was conducted to investigate the relationship between cholecystectomy/hepatectomy/pancreatectomy and the subsequent risk of devel...

journal_title：Journal of bone and mineral metabolism

authors： Cheng WZ,Lin YL,Su YC,Lin MC,Tseng CH,Lin RM,Huang ST

更新日期：2020-08-05 00:00:00

abstract：:Rodent hindlimb unloading (HU) by tail-suspension is a model to investigate disuse-induced bone loss in vivo. Previously, we have shown that osteopontin (OPN, also known as Spp1) is required for unloading-induced bone loss. However, how unloading affects OPN expression in the body is not fully understood. Here, we exa...

journal_title：Journal of bone and mineral metabolism

authors： Ezura Y,Nagata J,Nagao M,Hemmi H,Hayata T,Rittling S,Denhardt DT,Noda M

更新日期：2015-01-01 00:00:00

abstract：:The MOVEMENT study was designed to assess the effectiveness of monthly intravenous ibandronate on bone mineral density (BMD) in daily clinical practice in Japanese patients with primary osteoporosis whose lumbar spine BMD did not increase despite oral bisphosphonate therapy. This study was a multicenter, prospective, ...

journal_title：Journal of bone and mineral metabolism

authors： Hagino H,Sakai A,Ikeda S,Imanishi Y,Tsurukami H,Nakajo S,Miyakoshi N

更新日期：2019-11-01 00:00:00

abstract：:Syndecans are single-pass integral membrane components that serve as co-receptors for growth factors and cytokines and can elicit signal transduction via their cytoplasmic tails. We review here previous studies from our groups on syndecan-3 biology and function in the growth plates of developing long bones in chick an...

journal_title：Journal of bone and mineral metabolism

authors： Pacifici M,Shimo T,Gentili C,Kirsch T,Freeman TA,Enomoto-Iwamoto M,Iwamoto M,Koyama E

更新日期：2005-01-01 00:00:00

abstract：:Osteoporosis is the most common bone disease in humans. During bone remodeling, specialized blood vessels influenced by the endothelial cells (CD31hiEmcnhi, also called type H cells) are formatted to supply nutrients. Reductions in vascular supply are associated with bone loss resulting in osteoporosis. Therefore, the...

journal_title：Journal of bone and mineral metabolism

authors： Zhu Y,Ruan Z,Lin Z,Long H,Zhao R,Sun B,Cheng L,Tang L,Xia Z,Li C,Zhao S

更新日期：2019-11-01 00:00:00

abstract：:Vertebral fractures are the most common complication associated with osteoporosis. The definition of prevalent or incident vertebral fractures is important in epidemiological evaluation and in clinical trials of osteoporosis treatment. There have been few reports regarding the morphometric cutoff criteria for incident...

journal_title：Journal of bone and mineral metabolism

authors： Fukunaga M,Nakamura T,Shiraki M,Kuroda T,Ohta H,Hosoi T,Orimo H

更新日期：2004-01-01 00:00:00

abstract：:Bone development up to early adulthood plays an important role in determining the risk of osteoporosis later in life. However, bone development in children has not been fully documented by longitudinal studies in Japanese children. The purpose of this study is to determine the degree of tracking of areal bone mineral ...

journal_title：Journal of bone and mineral metabolism

authors： Fujita Y,Iki M,Ikeda Y,Morita A,Matsukura T,Nishino H,Yamagami T,Kagamimori S,Kagawa Y,Yoneshima H

更新日期：2011-03-01 00:00:00

abstract：INTRODUCTION:Physical activity (PA) is a key factor of bone mass acquisition in peripubertal children. Sedentary behavior (SB) has been shown to influence bone outcomes. This study aimed to examine the association between objectively measured PA and SB and bone stiffness in Japanese children. MATERIALS AND METHODS:Par...

journal_title：Journal of bone and mineral metabolism

authors： Yamakita M,Ando D,Akiyama Y,Sato M,Suzuki K,Yamagata Z

更新日期：2019-11-01 00:00:00

abstract：:Trabecular bone density at the distal radius and cortical bone density at the midradius were measured in four randomized groups of women before and after 4 months administration of AAACa, oyster shell heated under reduced pressure with addition of heated algal ingredient (HAI) (group A); AACa, the same preparation wit...

journal_title：Journal of bone and mineral metabolism

authors： Fujita T,Fujii Y,Goto B,Miyauchi A,Takagi Y

更新日期：2000-01-01 00:00:00

abstract：:This study aimed to identify the osteogenesis effect of icariside II (ICSII) and icaritin (ICT) in vitro. Bone marrow mesenchymal stem cells (BMSCs) were treated with ICSII and ICT in order to detect the proliferation and differentiation of BMSCs, the expression of the osteogenesis-related proteins with or without ost...

journal_title：Journal of bone and mineral metabolism

authors： Luo G,Xu B,Wang W,Wu Y,Li M

更新日期：2018-11-01 00:00:00

abstract：:Concurrent use of bisphosphonate therapy reduces the anabolic effect of teriparatide. Consequently, in clinical practice bisphosphonates are discontinued and teriparatide therapy held for a few months to allow bone turnover to increase. We aimed to evaluate the effect of prior bisphosphonate exposure and the effect of...

journal_title：Journal of bone and mineral metabolism

authors： Keel C,Kraenzlin ME,Kraenzlin CA,Müller B,Meier C

更新日期：2010-01-01 00:00:00