Abstract:
BACKGROUND:With improvements in technology, renal biopsies have become safer and could potentially be effectively carried out in the outpatient setting. The purpose of our study is to compare the safety and cost of performing outpatient versus inpatient renal biopsies at a single Northern California pediatric hospital. METHODS:We retrospectively studied the records of patients who underwent renal biopsy at our hospital during the period June 2001 to June 2006. Patients who were admitted to the hospital were compared with those who underwent biopsy as outpatients and were observed postprocedure for 4 hours for complications. RESULTS:54 patients underwent 60 biopsies as inpatients and 58 patients underwent 78 biopsies as outpatients. Two inpatients required intervention for bleeding. One patient in the outpatient group was readmitted for persistent gross hematuria that subsided without intervention, and another patient had an inadequate sample obtained. Considering physician, nursing and ancillary hospital charges for the inpatient stay, the difference in cost was US $4,133 per procedure. CONCLUSIONS:Our study suggests that discharging patients after a 4-hour monitoring period is a safe practice in a select group of patients. This practice has profound financial advantages by reducing health care costs and potentially improves patient satisfaction.
journal_name
J Nephroljournal_title
Journal of nephrologyauthors
Lau KK,Berg GL,Butani Lsubject
Has Abstractpub_date
2009-01-01 00:00:00pages
69-74issue
1eissn
1121-8428issn
1724-6059journal_volume
22pub_type
杂志文章abstract::A 64-year-old man was hospitalized in 2002 with symptoms of stupor, weakness, and renal colic. The clinical examination indicated borderline hypertension, small masses in the glutei, and polyuria. Laboratory tests evidenced high serum concentrations of creatinine, calcium, and phosphate. Imaging assessments disclosed ...
journal_title:Journal of nephrology
pub_type: 杂志文章
doi:10.1007/s40620-015-0228-7
更新日期:2016-02-01 00:00:00
abstract::The newly described endothelium-dependent vasoactive substances, nitric oxide and endothelins, have been the subject of intense investigative interest and have been demonstrated to promote a wide array of autocrine and paracrine functions. Recent data highlight their emerging role as potential important mediators of r...
journal_title:Journal of nephrology
pub_type: 杂志文章,评审
doi:
更新日期:1997-05-01 00:00:00
abstract::Lupus is now regarded as a syndrome which results from several related auto-immune processes, although the exact mechanisms of how the disease arises in susceptible individuals remain obscure. When the San Carlo meetings began in 1968, much less was known about the pathogenesis of autoimmunity, but the presence of aut...
journal_title:Journal of nephrology
pub_type: 杂志文章,评审
doi:
更新日期:1999-07-01 00:00:00
abstract::With increasingly accurate non-invasive tests, the clinician frequently discovers obstruction of the renal arteries by atherosclerosis. The decision to reverse this obstruction is not straightforward, particularly when blood pressure can be easily controlled with medications. Proper management of this problem requires...
journal_title:Journal of nephrology
pub_type: 杂志文章,评审
doi:
更新日期:1998-05-01 00:00:00
abstract:BACKGROUND:Reduced bone mineral density (BMD) is common in end-stage renal disease (ESRD) patients and predicts outcomes. The chronic kidney disease-mineral bone disorder contributes to low BMD in ESRD; however, the impact of classical risk factors for osteoporosis in the general population, such as body weight and fat...
journal_title:Journal of nephrology
pub_type: 杂志文章
doi:10.5301/jn.5000185
更新日期:2013-05-01 00:00:00
abstract::Evidence-based medicine provides tools to evaluate dialysis outcomes by integrating knowledge obtained from interventional and observational studies. This is illustrated in relation to three important topics: dialysis membranes, dialysis dose and anemia. Clinical trials and observational evidence support each other in...
journal_title:Journal of nephrology
pub_type: 杂志文章,评审
doi:
更新日期:2001-11-01 00:00:00
abstract:BACKGROUND:Different mitogens are involved in the pathogenesis of kidney damage after subtotal nephrectomy. One of them, TGF-beta, controls mesangial cell proliferation and interstitial fibrosclerosis. The transduction of the TGF-beta signal is controlled by intracellular signalling molecules such as Ras G monomeric pr...
journal_title:Journal of nephrology
pub_type: 杂志文章
doi:
更新日期:2002-09-01 00:00:00
abstract::The most common cause of liver disease worldwide is now non-alcoholic fatty liver disease (NAFLD). NAFLD refers to a spectrum of disease ranging from steatosis to non-alcoholic steatohepatitis, causing cirrhosis, and ultimately hepatocellular carcinoma. However, the impact of NAFLD is not limited to the liver. NAFLD h...
journal_title:Journal of nephrology
pub_type: 杂志文章,评审
doi:10.1007/s40620-020-00751-y
更新日期:2020-05-21 00:00:00
abstract::The pathogenetic role of adiponectin (ADPN) in kidney failure is not yet elucidated, since in vitro and in vivo studies have demonstrated that ADPN exerts both anti-inflammatory and pro-inflammatory effects. Starting from our previous findings demonstrating that HK-2 cells express and secrete ADPN, in this study we in...
journal_title:Journal of nephrology
pub_type: 杂志文章
doi:10.1007/s40620-015-0220-2
更新日期:2016-04-01 00:00:00
abstract::Ferumoxytol is a new product approved for intravenous use by the US Food and Drug Administration (FDA) in the treatment of iron deficiency anemia in adults with chronic kidney disease. This approval was based on data from 3 open-label, randomized, controlled clinical trials. In all of these trials, ferumoxytol was wel...
journal_title:Journal of nephrology
pub_type: 杂志文章,评审
doi:10.5301/jn.5000025
更新日期:2011-11-01 00:00:00
abstract:BACKGROUND:Renal tubular epithelial cells (TECs) function as antigen-presenting cells because they constitutively express MHC class II molecules and have the ability to present peptide antigen to CD4+T cells. However, the costimulatory signals provided by TECs for optimal T-cell activation have not been fully character...
journal_title:Journal of nephrology
pub_type: 杂志文章
doi:
更新日期:2006-07-01 00:00:00
abstract::Given the alarming predictions of the potentially devastating future epidemic of end-stage renal disease (ESRD), further knowledge is still urgently needed on this topic. The real dimensions of the problem are still unclear. It is difficult to compare Europe and the USA because different criteria are used in data coll...
journal_title:Journal of nephrology
pub_type: 杂志文章
doi:
更新日期:2005-03-01 00:00:00
abstract:BACKGROUND:Non-heart-beating donors suffer a period of warm ischaemia (WI) injury, resulting in higher rates of delayed graft function compared with heart-beating donors. Endothelin is believed to play a pathophysiological role in the intense vasospasm associated with WI. This study aimed to investigate renal function ...
journal_title:Journal of nephrology
pub_type: 杂志文章
doi:
更新日期:2009-01-01 00:00:00
abstract::On September 11, 1945, Maria Schafstaat was the first patient who successfully underwent a dialysis treatment for acute kidney injury (AKI). The ingenious design of the first dialysis machine, made of cellophane tubing wrapped around a cylinder that rotated in a bath of fluid, together with the brave determination to ...
journal_title:Journal of nephrology
pub_type: 杂志文章,评审
doi:
更新日期:2010-09-01 00:00:00
abstract::Rapidly progressive glomerulonephritis (RPGN) must be diagnosed and treated quickly to prevent irreversible organ injury. The commonest cause of RPGN is anti-neutrophil cytoplasm antibody (ANCA) associated small vessel vasculitis, and the most severe is anti-glomerular basement membrane (GBM) antibody disease. In this...
journal_title:Journal of nephrology
pub_type: 杂志文章,评审
doi:
更新日期:2004-11-01 00:00:00
abstract:BACKGROUND:Mesangial proliferative glomerulonephritis (MePGN) is characterized by excessive mesangial cell proliferation and mesangial matrix expansion, which lead to glomerular sclerosis and obliteration and, in turn, to deteriorating renal function. To identify and quantify the total proteins in renal tissues of MePG...
journal_title:Journal of nephrology
pub_type: 杂志文章
doi:10.5301/jn.5000124
更新日期:2013-01-01 00:00:00
abstract:AIMS:To examine the distribution of bone mineral density (BMD) in different histological groups of renal osteodystrophy. PATIENTS:We prospectively studied 62 patients, 41 men and 21 women, aged 57+/-11.5 years, who had been on hemodialysis for 60+/-55 months. The women had been amenorrheic for 13+/-4 years and 7 patie...
journal_title:Journal of nephrology
pub_type: 杂志文章
doi:
更新日期:2000-11-01 00:00:00
abstract::The term sarcopenia was first introduced in 1988 by Irwin Rosenberg to define a condition of muscle loss that occurs in the elderly. Since then, a broader definition comprising not only loss of muscle mass, but also loss of muscle strength and low physical performance due to ageing or other conditions, was developed a...
journal_title:Journal of nephrology
pub_type: 杂志文章,评审
doi:10.1007/s40620-020-00840-y
更新日期:2020-09-02 00:00:00
abstract::The partial correction of anemia and the normalization of phosphate and blood pressure are the mainstay of treatment of patients with chronic kidney disease (CKD). Available anti-hypertensive drugs, erythropoiesis stimulating agents (ESAs) and iron supplements have resolved quite satisfactorily the goal of controlling...
journal_title:Journal of nephrology
pub_type: 杂志文章,评审
doi:10.1007/s40620-017-0421-y
更新日期:2017-12-01 00:00:00
abstract:BACKGROUND:Coronary artery disease (CAD) and chronic kidney disease (CKD) lead to high morbidity and mortality rates. Traditional and nontraditional risk factors, hypertension, fluid overloading and anemia can lead to myocardial ischemia, chamber hypertrophy and dilatation, and low left ventricular ejection fraction (L...
journal_title:Journal of nephrology
pub_type: 杂志文章
doi:
更新日期:2010-03-01 00:00:00
abstract:BACKGROUND:Uromodulin (Tamm-Horsfall protein) is the most abundant urinary protein in healthy individuals. Despite 60 years of research, its physiological role remains rather elusive. Familial juvenile hyperuricemic nephropathy and medullary cystic kidney disease Type 2 are autosomal dominant tubulointerstitial nephrop...
journal_title:Journal of nephrology
pub_type: 杂志文章
doi:10.1007/s40620-014-0079-7
更新日期:2014-06-01 00:00:00
abstract::Cyclosporine A has been empirically used for more than 12 years in the treatment of idiopathic nephrotic syndrome, in both children and adults. There is consistent evidence, from both experimental and human studies, that the highly lipophilic cyclosporine molecule diminishes or abolishes proteinuria by two differing m...
journal_title:Journal of nephrology
pub_type: 杂志文章,评审
doi:
更新日期:1997-01-01 00:00:00
abstract::Bisphosphonates inhibit bone resorption and are widely used to treat osteolytic metastases and osteoporosis. Renal osteodystrophy patients have continuous bone loss due to chronically elevated parathyroid hormone (PTH). In this open-label study, ibandronate was evaluated for the treatment of reduced bone density in re...
journal_title:Journal of nephrology
pub_type: 杂志文章,随机对照试验
doi:
更新日期:2008-07-01 00:00:00
abstract::The analysis of the urinary proteome is a potential source of information regarding the kidney's physiopathology. A clear knowledge of the protein composition of normal urine is an essential prerequisite to looking at its pathology. Technological evolution in the field of proteomics (2-dimensional [2D] electrophoresis...
journal_title:Journal of nephrology
pub_type: 杂志文章,评审
doi:10.5301/jn.5000233
更新日期:2013-07-01 00:00:00
abstract:BACKGROUND:Adiponectin, a novel adipocytokine with antiinflammatory and antiatherosclerosis properties, has been found to be an inverse predictor of cardiovascular outcomes among uremic patients on hemodialysis. However, its role in uremic patients on continuous ambulatory peritoneal dialysis (CAPD) remains unclear. Th...
journal_title:Journal of nephrology
pub_type: 杂志文章
doi:
更新日期:2008-09-01 00:00:00
abstract::Jaundice and pancreatitis are serious complications in post renal transplantations; hepatotropic viruses and drugs are commonly implicated. We describe ascaris infestation causing pancreatitis and obstructive jaundice in a renal transplant patient. ...
journal_title:Journal of nephrology
pub_type: 杂志文章
doi:
更新日期:2004-05-01 00:00:00
abstract::Acute kidney injury (AKI) is an increasing health burden with high morbidity and mortality rates worldwide. AKI is a risk factor for chronic kidney disease (CKD) development and progression to end stage renal disease (ESRD). Rapid action is required to find treatment options for AKI, plus to anticipate the development...
journal_title:Journal of nephrology
pub_type: 杂志文章,评审
doi:10.1007/s40620-020-00793-2
更新日期:2020-12-01 00:00:00
abstract::The increase in progressive kidney disease, rising numbers of patients with end-stage renal disease, organ shortages for kidney transplants and poor long-term graft survival rates underline the need for better strategies to diagnose, prevent and treat renal disease. Histological analysis, based on renal biopsies and r...
journal_title:Journal of nephrology
pub_type: 杂志文章,评审
doi:10.5301/jn.5000205
更新日期:2012-09-01 00:00:00
abstract::The pathophysiological mechanisms underlying preeclampsia, a serious complication of pregnancy, are largely unknown. Since, on the other hand, the various risk factors are known, primary and secondary prevention with pre- and inter-pregnancy counseling should be undertaken, and a follow-up should be conducted to evalu...
journal_title:Journal of nephrology
pub_type: 杂志文章,评审
doi:
更新日期:2008-09-01 00:00:00
abstract::Clinical immunology laboratories play an essential role in diagnosis and monitoring of systemic lupus erythematosus (SLE). To obtain the best results in terms of diagnostic performance and clinical usefulness, the following recommendations should be fulfilled: Indirect immunofluorescence on Hep-2 cells remains the met...
journal_title:Journal of nephrology
pub_type: 杂志文章,评审
doi:
更新日期:2002-11-01 00:00:00