Abstract:
:Cyclic vomiting syndrome (CVS) is a disorder noted for its unique intensity of vomiting, repeated emergency department visits and hospitalizations, and reduced quality of life. It is often misdiagnosed due to the unappreciated pattern of recurrence and lack of confirmatory testing. Because no accepted approach to management has been established, the task force was charged to develop a report on diagnosis and treatment of CVS based upon a review of the medical literature and expert opinion. The key issues addressed were the diagnostic criteria, the appropriate evaluation, the prophylactic therapy, and the therapy of acute attacks. The recommended diagnostic approach is to avoid "shotgun" testing and instead to use a strategy of targeted testing that varies with the presence of 4 red flags: abdominal signs (eg, bilious vomiting, tenderness), triggering events (eg, fasting, high protein meal), abnormal neurological examination (eg, altered mental status, papilledema), and progressive worsening or a changing pattern of vomiting episodes. Therapeutic recommendations include lifestyle changes, prophylactic therapy (eg, cyproheptadine in children 5 years or younger and amitriptyline for those older than 5), and acute therapy (eg, 5-hydroxytryptamine receptor agonists, termed triptans herein, as abortive therapy, and 10% dextrose and ondansetron for those requiring intravenous hydration). This document represents the official recommendations of the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition for the diagnosis and treatment of CVS in children and adolescents.
journal_name
J Pediatr Gastroenterol Nutrjournal_title
Journal of pediatric gastroenterology and nutritionauthors
Li BU,Lefevre F,Chelimsky GG,Boles RG,Nelson SP,Lewis DW,Linder SL,Issenman RM,Rudolph CD,North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition.doi
10.1097/MPG.0b013e318173ed39subject
Has Abstractpub_date
2008-09-01 00:00:00pages
379-93issue
3eissn
0277-2116issn
1536-4801pii
00005176-200809000-00022journal_volume
47pub_type
共识发展会议,杂志文章abstract:BACKGROUND:Vedolizumab (VDZ) is effective for treating both adult and pediatric onset inflammatory bowel disease (IBD). Clinical outcomes, however, have been reported to be superior in patients naïve to anti-tumor necrosis factor (TNF). With the growing interest in endoscopic endpoints, we aimed to describe rates of mu...
journal_title:Journal of pediatric gastroenterology and nutrition
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journal_title:Journal of pediatric gastroenterology and nutrition
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1097/00005176-200011000-00016
更新日期:2000-11-01 00:00:00
abstract:OBJECTIVE:Our previous studies suggested that human milk proteases begin to hydrolyze proteins in the mammary gland and continue within the term infant' stomach. No research has measured milk protease and pepsin activity in the gastric aspirates of preterm infants after human milk feeding. This study investigated how t...
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journal_title:Journal of pediatric gastroenterology and nutrition
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doi:10.1097/MPG.0000000000001237
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journal_title:Journal of pediatric gastroenterology and nutrition
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doi:10.1097/00005176-198605000-00013
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journal_title:Journal of pediatric gastroenterology and nutrition
pub_type: 杂志文章
doi:10.1097/00005176-200101000-00010
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journal_title:Journal of pediatric gastroenterology and nutrition
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更新日期:1986-03-01 00:00:00
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journal_title:Journal of pediatric gastroenterology and nutrition
pub_type: 杂志文章,评审
doi:10.1097/MPG.0b013e31828b36ac
更新日期:2013-06-01 00:00:00
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journal_title:Journal of pediatric gastroenterology and nutrition
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journal_title:Journal of pediatric gastroenterology and nutrition
pub_type: 杂志文章,多中心研究
doi:10.1097/00005176-199708000-00004
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更新日期:1991-02-01 00:00:00
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journal_title:Journal of pediatric gastroenterology and nutrition
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journal_title:Journal of pediatric gastroenterology and nutrition
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doi:10.1097/01.mpg.0000239992.12646.df
更新日期:2006-10-01 00:00:00
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更新日期:2006-08-01 00:00:00
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doi:10.1097/MPG.0000000000000344
更新日期:2014-07-01 00:00:00
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doi:10.1097/00005176-200101000-00020
更新日期:2001-01-01 00:00:00
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doi:10.1097/00005176-200502000-00025
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journal_title:Journal of pediatric gastroenterology and nutrition
pub_type: 杂志文章
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更新日期:2008-01-01 00:00:00
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doi:10.1097/00005176-198201030-00018
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journal_title:Journal of pediatric gastroenterology and nutrition
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更新日期:2010-03-01 00:00:00
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journal_title:Journal of pediatric gastroenterology and nutrition
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doi:10.1097/MPG.0b013e31824e5f7a
更新日期:2012-08-01 00:00:00
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journal_title:Journal of pediatric gastroenterology and nutrition
pub_type: 临床试验,杂志文章,随机对照试验
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journal_title:Journal of pediatric gastroenterology and nutrition
pub_type: 杂志文章
doi:10.1097/00005176-199308000-00014
更新日期:1993-08-01 00:00:00
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更新日期:2006-03-01 00:00:00
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更新日期:1983-01-01 00:00:00