Inducible- and constitutive-type transcript variants of kakusei , a novel non-coding immediate early gene, in the honeybee brain.

Abstract:

:We previously identified a novel non-coding immediate early gene, termed kakusei , from the honeybee (Apis mellifera) and used it as a marker to detect neural activity in the brains of foraging workers (Kiya et al .,2007). Here, we investigated the detailed kakusei gene structure. Expression analysis revealed that, in addition to the neural activity-inducible transcript variant, multiple neural activity-independent transcript variants were constitutively expressed from the same kakusei locus. In situ hybridization revealed that constitutive-type kakusei variants were detected in the whole brain and the RNA was localized predominantly in the neural nuclei, like the inducible-type variant, suggesting the concerted action of inducible- and constitutive-types of kakusei transcript variants on nuclear function.

journal_name

Insect Mol Biol

journal_title

Insect molecular biology

authors

Kiya T,Kunieda T,Kubo T

doi

10.1111/j.1365-2583.2008.00821.x

subject

Has Abstract

pub_date

2008-09-01 00:00:00

pages

531-6

issue

5

eissn

0962-1075

issn

1365-2583

pii

IMB821

journal_volume

17

pub_type

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