A glutathione S-transferase gene of the vector mosquito, Anopheles gambiae.

Abstract:

:A cDNA (D7-8B) 1456 nucleotides in length was isolated from an adult, female-specific Anopheles gambiae library and identified as a member of the glutathione S-transferase (GST) gene family by virtue of the inferred amino acid sequence. The gene, AgGST2-1, specifies a protein that is 57% identical to the Drosophila melanogaster gene, DmGST-2. The conceptual translation product also shows similarity to the pi family of vertebrate GSTs. Northern analysis reveals multiple and abundant transcription products in larval, pupal and adult RNA preparations. Southern analyses of genomic DNA and hybridizations in situ to polytene chromosomes both suggest that there are multiple members of the GST gene family in Anopheles gambiae.

journal_name

Insect Mol Biol

journal_title

Insect molecular biology

authors

Reiss RA,James AA

doi

10.1111/j.1365-2583.1993.tb00122.x

subject

Has Abstract

pub_date

1993-01-01 00:00:00

pages

25-32

issue

1

eissn

0962-1075

issn

1365-2583

journal_volume

2

pub_type

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