Quantification of left ventricular function and mass in heart transplant recipients using dual-source CT and MRI: initial clinical experience.

Abstract:

:The purpose of this study was to compare LV function and mass quantification derived from cardiac dual-source CT (DSCT) exams with those obtained by MRI in heart transplant recipients. Twelve heart transplant recipients who underwent cardiac DSCT and MRI examination were included. Double-oblique short-axis 8-mm slice thickness images were evaluated. Left ventricular ejection fraction, end-diastolic volume, end-systolic volume, stroke volume, cardiac output and myocardial mass were manually assessed for each patient by two blinded readers. A systematic overestimation of all left ventricular volumes by DSCT when compared with MRI was observed. Mean difference was 16.58 +/- 18.61 ml for EDV, 4.9 4 +/- 6.84 ml for ESV, 11.64 +/- 13.58 ml for SV and 5.73 +/- 1.14 l/min for CO. Slightly lower values for left ventricular ejection fraction with DSCT compared with MRI were observed (mean difference 0.34 +/- 3.18%, p = 0.754). Correlation between DSCT and MRI for left ventricular mass was excellent (rho = 0.972). Bland and Altman plots and CCC indicated good agreement between DSCT and MRI left ventricular function and mass measurements. The interobserver correlation was good. In conclusion, DSCT accurately estimates left ventricular ejection fraction, volumes and mass in heart transplant recipients.

journal_name

Eur Radiol

journal_title

European radiology

authors

Bastarrika G,Arraiza M,De Cecco CN,Mastrobuoni S,Ubilla M,Rábago G

doi

10.1007/s00330-008-0949-2

subject

Has Abstract

pub_date

2008-09-01 00:00:00

pages

1784-90

issue

9

eissn

0938-7994

issn

1432-1084

journal_volume

18

pub_type

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