Abstract:
OBJECTIVES:Metastatic breast cancer is a heterogeneous disease, commonly affecting the liver. We report our experience with (90)Y radioembolisation (RE) and its effects on the survival of patients with treatment-refractory breast cancer liver metastases. METHODS:A total of 77 female patients affected by breast cancer were accepted into our department for RE. Inclusion criteria were inoperable and chemotherapy-refractory hepatic metastases, acceptable performance status, sufficient residual liver, no significant hepato-pulmonary shunts. Patients were divided in two groups: group 1 (29 patients) included those with Eastern Cooperative Oncology Group (ECOG) score 0, liver involvement (0-25 %) and no extrahepatic disease (EHD); group 2 (23 patient) included patients with ECOG score 1-2, liver involvement (26-50 %) and evidence of EHD. RESULTS:A total of 25 patients were considered ineligible. The median age of the remaining 52 patients was 57.5 years. The median overall survival was 11.5 months and better in those whose performance status and liver function were preserved (14.3 versus 8.2 months). According to Response Evaluation Criteria in Solid Tumor (RECIST), partial response (PR) was achieved in 29 patients (56 %), stable disease (SD) was achieved in a further 18 patients (35 %) and 5 patients showed progressive disease (PD) (10 %). DISCUSSION:(90)Y RE is effective in the treatment of liver metastases from breast cancer. We demonstrated a relevant survival and encouragingly high response rate in patients with treatment-refractory disease.
journal_name
Eur Radioljournal_title
European radiologyauthors
Cianni R,Pelle G,Notarianni E,Saltarelli A,Rabuffi P,Bagni O,Filippi L,Cortesi Edoi
10.1007/s00330-012-2556-5subject
Has Abstractpub_date
2013-01-01 00:00:00pages
182-9issue
1eissn
0938-7994issn
1432-1084journal_volume
23pub_type
杂志文章abstract::Placenta percreta is a potentially life-threatening complication of pregnancy, which is increasing in incidence. Ante-natal diagnosis with ultrasound and magnetic resonance imaging aids the obstetric team in planning further management. We present a case of placenta percreta with imaging and a brief review of the lite...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-006-0498-5
更新日期:2007-06-01 00:00:00
abstract:OBJECTIVES:Normative brain volume reports (NBVRs) are becoming more and more available for the workup of dementia patients in clinical routine. However, it is yet unknown how this information can be used in the radiological decision-making process. The present study investigates the diagnostic value of NBVRs for detect...
journal_title:European radiology
pub_type: 杂志文章
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journal_title:European radiology
pub_type: 杂志文章
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abstract::The goal of this study was to analyze the diagnostic value of three-dimensional time-of-flight magnetic resonance angiography (3D TOF MRA), performed on a 0.5-T system in the detection of neurovascular compression in patients with trigeminal neuralgia (TN). One hundred seventy-two TN patients were examined using plain...
journal_title:European radiology
pub_type: 杂志文章
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更新日期:2001-01-01 00:00:00
abstract:OBJECTIVES:To describe a randomized controlled trial (RCT) of digital breast tomosynthesis including synthesized two-dimensional mammograms (DBT) versus digital mammography (DM) in a population-based screening program for breast cancer and to compare selected secondary screening outcomes for the two techniques. METHOD...
journal_title:European radiology
pub_type: 杂志文章,多中心研究,随机对照试验
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abstract::The aim of this study was to compare our computer-aided report writing system to standard techniques. A computer-aided reporting system for reporting on chest X-rays was developed and linked with a UNIX-based radiology information system. The reporting system consists of different text modules which can be composed to...
journal_title:European radiology
pub_type: 杂志文章
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更新日期:1998-01-01 00:00:00
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journal_title:European radiology
pub_type: 杂志文章
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journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s10406-004-0088-z
更新日期:2004-10-01 00:00:00
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journal_title:European radiology
pub_type: 杂志文章
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更新日期:2009-03-01 00:00:00
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journal_title:European radiology
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更新日期:2017-03-01 00:00:00
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更新日期:2015-05-01 00:00:00
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journal_title:European radiology
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更新日期:2010-05-01 00:00:00
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pub_type: 临床试验,杂志文章
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更新日期:2007-10-01 00:00:00
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pub_type: 杂志文章
doi:10.1007/s00330-019-06574-1
更新日期:2020-04-01 00:00:00
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journal_title:European radiology
pub_type: 杂志文章,多中心研究,随机对照试验
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更新日期:2020-05-01 00:00:00
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更新日期:2018-08-01 00:00:00
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journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-014-3144-7
更新日期:2014-06-01 00:00:00
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journal_title:European radiology
pub_type: 杂志文章,评审
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更新日期:2004-05-01 00:00:00
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journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-002-1805-4
更新日期:2003-12-01 00:00:00
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pub_type: 杂志文章
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更新日期:2016-11-01 00:00:00
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journal_title:European radiology
pub_type: 杂志文章
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更新日期:2003-07-01 00:00:00
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更新日期:2019-04-01 00:00:00
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journal_title:European radiology
pub_type: 杂志文章
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更新日期:2015-09-01 00:00:00
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pub_type: 杂志文章
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更新日期:2002-05-01 00:00:00