Abstract:
OBJECTIVES:Olfactory dysfunction in Parkinson's disease is usually prodromal to other symptoms. In this study, we aimed to explore the association of olfactory function with the availabilities of striatal dopamine transporter (DAT) in healthy subjects. METHODS:Data used in the preparation of this article were obtained from Parkinson's Progression Markers Initiative database ( www.ppmi-info.org/data ). The study population consisted of healthy controls with screening 123I-FP-CIT single photon emission tomography (SPECT). University of Pennsylvania Smell Identification Test (UPSIT) was assessed to evaluate the olfactory function. RESULTS:Totally, 181 healthy subjects (117 male, 64 female) with 123I-FP-CIT SPECT data were included in this study. Specific binding ratios (SBRs) of the caudate nucleus (rho = -0.4217, p < 0.0001), putamen (rho = -0.2292, p = 0.0019), and striatum (rho=-0.3425, p < 0.0001) showed a reduction with ageing. SBRs of the caudate nucleus, putamen, and striatum were positively correlated with UPSIT (rho = 0.3716, p < 0.0001; rho = 0.3655, p < 0.0001; rho = 0.3880, p < 0.0001). After controlling for age by partial correlation, SBRs of the caudate nucleus, putamen, and striatum showed an influence on UPSIT (rho = 0.3288, p < 0.0001; rho = 0.3374, p < 0.0001; rho = 0.3511, p < 0.0001). CONCLUSION:Olfactory function is associated with the availability of striatal DAT independent of age in healthy subjects. KEY POINTS:• Olfactory dysfunction in Parkinson's disease is prodromal to other symptoms. • The availability of dopamine transporter showed a reduction with ageing. • Olfactory function is associated with the availability of dopamine transporter.
journal_name
Eur Radioljournal_title
European radiologyauthors
Pak K,Kim K,Lee MJ,Lee JM,Kim BS,Kim SJ,Kim IJdoi
10.1007/s00330-017-5147-7subject
Has Abstractpub_date
2018-04-01 00:00:00pages
1756-1760issue
4eissn
0938-7994issn
1432-1084pii
10.1007/s00330-017-5147-7journal_volume
28pub_type
杂志文章abstract:OBJECTIVE:To retrospectively compare semi-automated and manual volume measurements of malignant liver tumours and inter- and intra-observer variability using commercially available software. METHODS:This study was performed on 60 consecutive patients with untreated liver metastases (30) and HCCs (30), i.e. 92 lesions ...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-010-2013-2
更新日期:2011-05-01 00:00:00
abstract:OBJECTIVES:To assess the risk of lung cancer and specific mortality rate in patients with and without solitary pulmonary nodules (SPN) on chest radiograph and CT. METHODS:This prospective study included 16,078 patients ≥35 years old (893 of them had an SPN detected with either chest radiograph or CT) and 15,185 withou...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-015-3775-3
更新日期:2015-12-01 00:00:00
abstract::Our objective was to quantify water volume using magnetic resonance cholangiopancreatography (MRCP) sequences and apply this to secretin-stimulated studies with the aim of quantifying pancreatic exocrine function. A commercially available single-shot MRCP sequence was used in conjunction with a body phased-array coil ...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-002-1605-x
更新日期:2003-02-01 00:00:00
abstract:OBJECTIVE:It is controversial to adopt non-invasive diagnostic criteria of hepatocellular carcinoma (HCC) in subcentimeter lesions. This study was aimed to define the optimal noninvasive diagnostic criteria of subcentimeter HCC and to evaluate the effect on tumor staging. METHODS:We included 110 treatment-naïve patien...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-020-07329-z
更新日期:2020-10-12 00:00:00
abstract:OBJECTIVES:To determine whether phase-contrast X-ray imaging can be used to visualise directly the accumulated extracellular matrix proteins associated with liver fibrosis in common bile duct ligated mice. METHODS:Twenty-six-week-old C57BL female mice were randomised into three groups. In groups 1 (n = 5) and 2 (n = 1...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-012-2630-z
更新日期:2013-02-01 00:00:00
abstract::Stress fractures are common injuries frequently overlooked on first radiographs, especially in the early course. The gold standard for accurate diagnosis is MRI and scintigraphy. We report six cases of stress fractures of the lower limb diagnosed with sonography and describe typical sonographic features. ...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-004-2525-8
更新日期:2005-02-01 00:00:00
abstract:OBJECTIVE:To assess severity and factors of pain during high-intensity focused ultrasound (HIFU) ablation of benign thyroid nodules. METHODS:128 patients who underwent a HIFU ablation for a benign thyroid nodule were analysed. All patients received a bolus of intravenous pethidine and diazepam before treatment. After ...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-017-5200-6
更新日期:2018-06-01 00:00:00
abstract::This article presents a case of leiomyosarcomatosis with widespread lesions involving the soft tissues and the most unlikely organs such as thyroid and salivary glands, pancreas, ligamentum teres, bladder wall, and bones without lymph node or distant metastasis. The CT and US findings of this rare phenomenon are discu...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s003300050738
更新日期:1999-01-01 00:00:00
abstract:PURPOSE:We compared carotid plaque calcification detection sensitivity and apparent cross-sectional area on CT as a function of CT beam energy using conventional CT techniques and virtual mono-energetic CT images generated from dual-energy acquisitions. METHODS & MATERIALS:Five ex-vivo carotid endarterectomy (CEA) spe...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-014-3523-0
更新日期:2015-05-01 00:00:00
abstract:OBJECTIVE:To determine the diagnostic accuracy of diffusion-weighted (DW) magnetic resonance (MR) imaging in the preoperative assessment of myometrial invasion by endometrial cancer. MATERIALS AND METHODS:In this prospective study, 47 patients with histologically confirmed endometrial cancer underwent preoperative MR ...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-009-1597-x
更新日期:2010-03-01 00:00:00
abstract::The magnetic resonance (MR) guidance of endovascular interventions is probably one of the greatest challenges of clinical MR research. MR angiography is not only an imaging tool for the vasculature but can also simultaneously depict high tissue contrast, including the differentiation of the vascular wall and perivascu...
journal_title:European radiology
pub_type: 杂志文章,评审
doi:10.1007/s00330-007-0818-4
更新日期:2008-04-01 00:00:00
abstract::We report a case of renal cell carcinoma with solitary metachronous contralateral adrenal metastasis occurring 23 years after radical nephrectomy. The patient was treated with adrenalectomy. He is alive with no evidence of disease 1 year postoperatively. Solitary metachronous contralateral adrenal metastases from rena...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s003300050204
更新日期:1997-01-01 00:00:00
abstract::The purpose of the present study was to evaluate the usefulness of a new gray-scale test pattern (NGTP) that was developed to easily adjust the gradients of thoracic CT imaging and enable visual consistency. The Society of Motion Picture and Television Engineers (SMPTE) pattern and the NGTP were used for comparison. T...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-004-2315-3
更新日期:2004-12-01 00:00:00
abstract::The aim of this study was to determine the pathway of infrahyoid extension of the oropharyngeal abscess considering the anatomy of the fascial spaces by cross-sectional imaging. CT scans and MR images were retrospectively reviewed in ten patients with known infrahyoid extension of oropharyngeal abscesses (eight with a...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s003300050495
更新日期:1998-01-01 00:00:00
abstract:OBJECTIVE:To explore the predictive value of MRI parameters and tumour characteristics before neoadjuvant chemotherapy (NAC) and to compare changes in tumour size and tumour apparent diffusion coefficient (ADC) during treatment, between patients who achieved pathological complete response (pCR) and those who did not. ...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-010-2020-3
更新日期:2011-06-01 00:00:00
abstract:OBJECTIVES:To determine whether sirolimus has beneficial effects on lymphangioleiomyomatosis (LAM) lung cysts in CT with long-term follow-up (FU) and to investigate whether CT is an appropriate imaging biomarker to monitor and evaluate LAM progression. METHODS:In this retrospective study, 73 female patients diagnosed ...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-019-06412-4
更新日期:2020-02-01 00:00:00
abstract:OBJECTIVE:To investigate the value of pre-treatment amide proton transfer-weighted (APTw) imaging for predicting survival of patients with nasopharyngeal carcinoma (NPC). MATERIALS AND METHODS:Pre-treatment APTw imaging was performed in 77 NPC patients and the mean, 90th percentile, skewness, and kurtosis of APT asymm...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-020-06985-5
更新日期:2020-11-01 00:00:00
abstract::The purpose of this study was to use cine-MRI during continuous respiration to measure the respiratory lumenal diameter change in the pharynx and at an upper tracheal level. Fifteen non-smokers and 23 chronic obstructive pulmonary disease (COPD) patients with smoking history (median 50 pack-years) were included. Cine-...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-004-2461-7
更新日期:2004-12-01 00:00:00
abstract:OBJECTIVES:To compare image quality and radiation dose of abdominal split-filter dual-energy CT (SF-DECT) combined with monoenergetic imaging to single-energy CT (SECT) with automatic tube voltage selection (ATVS). METHODS:Two-hundred single-source abdominal CT scans were performed as SECT with ATVS (n = 100) and SF-D...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-018-5338-x
更新日期:2018-08-01 00:00:00
abstract:UNLABELLED:Imaging plays an increasingly important role in the early diagnosis, prognosis prediction and therapy response evaluation of central nervous system (CNS) diseases. The newly emerging hybrid positron emission tomography/magnetic resonance imaging (PET/MRI) can perform "one-stop-shop" evaluation, including ana...
journal_title:European radiology
pub_type: 杂志文章,评审
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更新日期:2016-10-01 00:00:00
abstract:OBJECTIVE:To investigate the relationship between paraspinal and psoas muscle volumes and acute osteoporotic or low-bone-mass compression fractures of the lumbar spine in postmenopausal women. METHODS:Patient data were retrieved retrospectively for postmenopausal women with L-spine magnetic resonance imaging (MRI) and...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-019-06034-w
更新日期:2019-09-01 00:00:00
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journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-017-5293-y
更新日期:2018-08-01 00:00:00
abstract:PURPOSE:In this retrospective study we examined whether size is a viable marker of tumour malignancy in soft tissue masses (STM) and if the ratio of width and length (RALD) of an STM reflects tumour biology more accurately. METHODS:Measurements of maximal lesion size and perpendicular diameter were performed in availa...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-016-4300-z
更新日期:2016-12-01 00:00:00
abstract::The increasing availability of high-field (3 T) MR scanners requires adapting and optimizing clinical imaging protocols to exploit the theoretically higher signal-to-noise ratio (SNR) of the higher field strength. Our aim was to establish reliable and stable protocols meeting the clinical demands for imaging the neuro...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-003-1984-7
更新日期:2003-09-01 00:00:00
abstract::To purpose of this paper is to study the relation between normal lung maturation signal and changes in intensity ratios (SIR) and to determine which magnetic resonance imaging sequence provides the strongest correlation of normal lung SIs with gestational age. 126 normal singleton pregnancies (20-37 weeks) were examin...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-006-0409-9
更新日期:2007-03-01 00:00:00
abstract::The aim of this study was to evaluate the validity and reproducibility of breath-hold and respiratory triggered phase-contrast (PC) MR imaging techniques in the measurement of renal artery blood flow. In 12 healthy subjects cardiac-gated PC flow measurements were obtained in the renal arteries using a breath-hold and ...
journal_title:European radiology
pub_type: 临床试验,杂志文章
doi:10.1007/s003300000362
更新日期:2000-01-01 00:00:00
abstract::The purpose of the study was to evaluate a semiautomatic analysis tool for assessing global left ventricular myocardial function with multislice computed tomography (MSCT). We examined 33 patients with MSCT using 16x0.5 mm detector collimation and magnetic resonance imaging (MRI) on a 1.5-T scanner. MSCT data were ana...
journal_title:European radiology
pub_type: 临床试验,杂志文章
doi:10.1007/s00330-005-2817-7
更新日期:2006-01-01 00:00:00
abstract:OBJECTIVE:To objectively quantify intracranial hematoma (ICH) enlargement by analysing the image texture of head CT scans and to provide objective and quantitative imaging parameters for predicting early hematoma enlargement. METHODS:We retrospectively studied 108 ICH patients with baseline non-contrast computed tomog...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-018-5364-8
更新日期:2018-10-01 00:00:00
abstract:OBJECTIVES:Various imaging methods have been evaluated regarding non-invasive differentiation of renal cell carcinoma (RCC) subtypes. Dual-energy computed tomography (DECT) allows iodine concentration (IC) analysis as a correlate of tissue perfusion. Microvascular density (MVD) in histopathology specimens is evaluated ...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-019-06298-2
更新日期:2020-01-01 00:00:00
abstract:OBJECTIVES:To determine whether liver function as determined by indocyanine green (ICG) clearance can be estimated quantitatively from hepatic magnetic resonance (MR) relaxometry with gadoxetic acid (Gd-EOB-DTPA). METHODS:One hundred and seven patients underwent an ICG clearance test and Gd-EOB-DTPA-enhanced MRI, incl...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-015-3919-5
更新日期:2016-04-01 00:00:00