Abstract:
OBJECTIVES:To determine whether phase-contrast X-ray imaging can be used to visualise directly the accumulated extracellular matrix proteins associated with liver fibrosis in common bile duct ligated mice. METHODS:Twenty-six-week-old C57BL female mice were randomised into three groups. In groups 1 (n = 5) and 2 (n = 10), common bile duct ligation was conducted to produce secondary biliary cirrhosis. Mouse livers were then excised 15 (group 1) and 40 days (group 2) after the ligation of the common bile duct for imaging. In the control group, the livers of 5 mice were excised 40 days after the sham operation. Images were then acquired using the analyser crystal set at different positions of the rocking curve. RESULTS:The results show that the fibrotic septa and hepatic lobules enclosed by fibrotic septa can be visualised clearly at the whole organ level via phase-contrast X-ray imaging without any contrast agent. CONCLUSION:These results suggest that phase-contrast X-ray imaging can easily reveal the accumulated extracellular matrix proteins associated with liver fibrosis without using any contrast agent and has great potential in the study of liver fibrosis.
journal_name
Eur Radioljournal_title
European radiologyauthors
Zhang X,Yang XR,Chen Y,Li HQ,Li RM,Yuan QX,Zhu PP,Huang WX,Peng WJdoi
10.1007/s00330-012-2630-zsubject
Has Abstractpub_date
2013-02-01 00:00:00pages
417-23issue
2eissn
0938-7994issn
1432-1084journal_volume
23pub_type
杂志文章abstract::Here we report our experience of a neuroprotective adaptation of the technique of CT-guided radiofrequency (RF) ablation of spinal osteoid osteomas. Over 9 years seven patients underwent eight CT-guided RF treatments for osteoid osteoma. CT-guided RF ablation was performed with general anaesthesia. The lesion was heat...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-009-1404-8
更新日期:2009-09-01 00:00:00
abstract:OBJECTIVE:The purpose of this study is to describe a new method to quickly estimate left atrial enlargement (LAE) on Computed Tomography. METHODS:Left atrial (LA) volume was assessed with a 3D-threshold Hounsfield unit detection technique, including left atrial appendage and excluding pulmonary venous confluence, in 2...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-017-5041-3
更新日期:2018-03-01 00:00:00
abstract:OBJECTIVE:To compare cardiac left ventricular (LV) parameters in simultaneously acquired hybrid fluorine-18-fluorodeoxyglucose ([18F] FDG) positron emission tomography/magnetic resonance imaging (PET/MRI) in patients with residual tracer activity of upstream PET/CT. METHODS:Twenty-nine patients (23 men, age 58±17 year...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-017-4896-7
更新日期:2017-12-01 00:00:00
abstract:KEY POINTS:• Abbreviated MRI (AMRI) protocols consist of acquiring only a minimal number of MRI sequences for HCC surveillance with acceptable diagnostic performance compared to complete MRI.• AMRI protocol options include non-contrast AMRI, dynamic AMRI or hepatobiliary phase AMRI post gadoxetate injection.• The best ...
journal_title:European radiology
pub_type: 社论
doi:10.1007/s00330-020-06904-8
更新日期:2020-08-01 00:00:00
abstract::The original version of this article, published on 14 March 2019, unfortunately contained a mistake. ...
journal_title:European radiology
pub_type: 已发布勘误
doi:10.1007/s00330-019-06184-x
更新日期:2019-07-01 00:00:00
abstract:OBJECTIVE:To assess the efficacy of computed diffusion-weighted images (cDWIs) of b = 2000 s/mm(2) (cDWI2000) generated from DWIs of b = 0 and 1000 for prostate cancer (PCa) diagnosis in comparison with that of measured original DWIs of b = 1000 (mDWI1000) and b = 2000(mDWI2000) using 3-T MRI. METHODS:Eighty patients ...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-013-2958-z
更新日期:2013-12-01 00:00:00
abstract::Diffusion-weighted imaging allows for measurement of tissue microstructure and reflects the random motion of water protons. It provides a new method to study bone marrow and bone marrow alterations on the basis of altered water-proton mobility in various diseases. Different diffusion-weighted methods have proved to be...
journal_title:European radiology
pub_type: 杂志文章,评审
doi:10.1007/s00330-003-1873-0
更新日期:2003-07-01 00:00:00
abstract::The diagnostic relevance of the relative T1-weighted (T1W) and T2-weighted (T2W)/short tau inversion recovery (STIR) MRI signal intensity characteristics of the superior to inferior fluid layers within fluid-fluid levels (FFLs) found in bone tumours was investigated. A retrospective analysis was performed of MRI studi...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-008-1060-4
更新日期:2008-11-01 00:00:00
abstract::The purpose was to evaluate low-dose CT colonography without cathartic cleansing in terms of image quality, polyp visualization and patient acceptance. Sixty-one patients scheduled for colonoscopy started a low-fiber diet, lactulose and amidotrizoic-acid for fecal tagging 2 days prior to the CT scan (standard dose, 5....
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-007-0668-0
更新日期:2007-12-01 00:00:00
abstract::Axillary management in patients with breast cancer has become much less invasive with the introduction of sentinel lymph node biopsy (SLNB). However, over 70 % of SLNBs are negative, questioning the generic use of this invasive procedure. Emerging evidence indicates that breast cancer patients with a low axillary burd...
journal_title:European radiology
pub_type: 杂志文章,评审
doi:10.1007/s00330-013-3009-5
更新日期:2014-02-01 00:00:00
abstract::The aim of this study was to evaluate the value of automatic bolus tracking for monophasic spiral CT of the liver and to assess the liver-to-lesion conspicuity in comparison with time-delay examinations. In 40 patients scheduled for therapy control of known hypovascular hepatic metastases a monophasic spiral CT was co...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s003300000637
更新日期:2001-01-01 00:00:00
abstract::Multi-detector-row computed tomography (MDCT) has emerged as a rapidly developing method for non-invasive imaging of the heart. An understanding of ECG synchronization, contrast material administration, patient preparation and image post-processing is needed to optimize image quality. The basic technical principles an...
journal_title:European radiology
pub_type: 杂志文章,评审
doi:10.1007/s00330-006-0433-9
更新日期:2007-04-01 00:00:00
abstract:OBJECTIVES:To investigate if brain gamma-aminobutyric acid (GABA) levels in patients with relapsing-remitting multiple sclerosis (RRMS) are abnormal compared with healthy controls, and their relationship to cognitive function in RRMS. METHODS:Twenty-eight RRMS patients and twenty-six healthy controls underwent magneti...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-017-5064-9
更新日期:2018-03-01 00:00:00
abstract:OBJECTIVES:To develop and prospectively validate a novel weighted quantitative scoring system based on CT findings, namely, the renal cyst index (RCI), aimed at preoperatively predicting the pathological features of cystic renal masses (CRMs). METHODS:The RCI was based on four critical features of CRMs: the cyst wall,...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-018-5722-6
更新日期:2019-04-01 00:00:00
abstract::The aim was to compare the performances of contrast-enhanced (CE) ultrasonography (US) and spiral computed tomography (CT) in the detection and characterization of portal vein thrombosis complicating hepatocellular carcinoma (HCC). We studied 50 patients with HCC who had biopsy-proven portal vein thrombi that had been...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-008-0931-z
更新日期:2008-08-01 00:00:00
abstract:OBJECTIVES:To investigate the diagnostic performance of reduced-dose CT with a hybrid iterative reconstruction (IR) algorithm for the detection of hypervascular liver lesions. METHODS:Thirty liver phantoms with or without simulated hypervascular lesions were scanned with a 320-slice CT scanner with control-dose (40 mA...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-016-4687-6
更新日期:2017-07-01 00:00:00
abstract:OBJECTIVE:To investigate dual-energy CT of hypervascular liver lesions in patients with HCC. METHODS:Forty patients with hepatocellular carcinomas were investigated with abdominal dual-energy CT. In each patient unenhanced and contrast-enhanced imaging with arterial und portovenous delay were performed. Hypervascular ...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-010-1964-7
更新日期:2011-04-01 00:00:00
abstract::The development and progression of a hepatocellular carcinoma (HCC) in a chronically diseased liver, i.e., the carcinogenesis, comprise a multistep and long-term process. Morphologically, this process is associated with the presence of distinct nodular lesions in the liver that are called 'preneoplastic lesions.' Thes...
journal_title:European radiology
pub_type: 杂志文章,评审
doi:10.1007/s00330-007-0602-5
更新日期:2007-10-01 00:00:00
abstract:OBJECTIVES:To compare the conspicuity of different histopathological types of breast cancer according to breast density and mammographic imaging in patients with screen-detected breast cancers undergoing both full-field digital mammography (FFDM) and screen-film mammography (SFM) in the United Kingdom National Health S...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-010-1906-4
更新日期:2011-01-01 00:00:00
abstract:OBJECTIVES:To assess the usefulness of C-arm cone-beam computed tomography (CBCT) virtual navigation-guided percutaneous mediastinal mass biopsy in terms of diagnostic accuracy and complication rates. METHODS:Seventy-eight CBCT virtual navigation-guided percutaneous mediastinal mass biopsies were performed in 75 patie...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-015-3762-8
更新日期:2015-12-01 00:00:00
abstract:OBJECTIVES:To establish the role of unenhanced CT in predicting the outcome of liver hydatid cysts. We sought to determine whether the presence of laminated membrane detachment (LMD) or pericyst degenerative changes (PDCs) detected on CT were reliable signs for predicting a favorable outcome of liver hydatids. METHODS...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-020-07681-0
更新日期:2021-01-16 00:00:00
abstract:PURPOSE:To evaluate magnetic resonance imaging (MRI) for diaphragmatic endometriosis diagnosis. MATERIALS AND METHODS:Over a 2-year period, all diaphragmatic MRI performed in the context of diaphragmatic endometriosis were reviewed. Axial and coronal fat-suppressed T1- and T2-weighted sequences were analyzed by two in...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-016-4226-5
更新日期:2016-11-01 00:00:00
abstract:OBJECTIVES:To determine whether dynamic contrast-enhanced (DCE) magnetic resonance imaging (MRI) can differentiate benign from malignant cartilage tumours compared to standard MRI. To investigate whether a cutoff value could be determined to differentiate enchondroma from low-grade chondrosarcoma (CS) more accurately. ...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-013-2913-z
更新日期:2013-11-01 00:00:00
abstract::The purpose of this study was to use cine-MRI during continuous respiration to measure the respiratory lumenal diameter change in the pharynx and at an upper tracheal level. Fifteen non-smokers and 23 chronic obstructive pulmonary disease (COPD) patients with smoking history (median 50 pack-years) were included. Cine-...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-004-2461-7
更新日期:2004-12-01 00:00:00
abstract:OBJECTIVE:To evaluate the performance of a computer-aided algorithm for automated stenosis detection at coronary CT angiography (cCTA). METHODS:We investigated 59 patients (38 men, mean age 58 +/- 12 years) who underwent cCTA and quantitative coronary angiography (QCA). All cCTA data sets were analyzed using a softwar...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-009-1644-7
更新日期:2010-05-01 00:00:00
abstract::The aim of this study was to evaluate MR imaging findings of the associated findings in surrounding tissues of the extra-articular soft tissue ganglion cysts around the knee. We retrospectively reviewed MR images of 30 patients who had surgically confirmed extra-articular soft tissue ganglion cysts around the knee wit...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-003-1969-6
更新日期:2004-01-01 00:00:00
abstract:OBJECTIVE:Determination of coronary artery calcium scoring (CACS) in non-contrast computed tomography (CT) images has been shown to be an important prognostic factor in coronary artery disease (CAD). The objective of this study was to evaluate the accuracy of CACS from virtual non-contrast (VNC) imaging generated from ...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-020-07677-w
更新日期:2021-01-20 00:00:00
abstract::The aim of this study was to describe a new magnetic resonance imaging (MRI) classification system for intra-articular soft tissue tumours based on the morphology of the lesion, with the aim to aid the differential diagnosis. We performed a retrospective review of 52 consecutive patients presenting to a specialist mus...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-006-0381-4
更新日期:2007-04-01 00:00:00
abstract::CT pneumocolon is a promising new technique in the diagnosis and management of colon pathology. CT pneumocolon can detect (sensitivity >95%) and stage (accuracy 79%) colorectal cancer and is very accurate in the differentiation of malignant from benign colonic pathologies. It has excellent detection rates for polyps >...
journal_title:European radiology
pub_type: 杂志文章,评审
doi:10.1007/s003300100890
更新日期:2001-01-01 00:00:00
abstract::The safety of the non-ionic contrast medium iopentol (Imagopaque, Nycomed Imaging AS, Oslo, Norway) when used in cerebral angiography and aortic arch angiography, was the focus of this investigation. Overall quality of visualization and changes in heart rate and blood pressure were, however, also assessed. In total, 3...
journal_title:European radiology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1007/pl00006884
更新日期:1997-01-01 00:00:00