Abstract:
OBJECTIVES:To assess the risk of lung cancer and specific mortality rate in patients with and without solitary pulmonary nodules (SPN) on chest radiograph and CT. METHODS:This prospective study included 16,078 patients ≥35 years old (893 of them had an SPN detected with either chest radiograph or CT) and 15,185 without SPN. Patients were followed up for 18 months or until being diagnosed with lung cancer. Risk and mortality lung cancer were calculated in both groups with Poisson regression. RESULTS:In patients with SPN, incidence of lung cancer was 8.3 % (95 % CI 6.0-11.2) on radiograph and 12.4 % (95 % CI 9.3-15.9) on CT. A chronic obstructive pulmonary disease in patients with radiographs (odds ratio 2.62; 95 % CI 1.03, 6.67) and smoking habit (odds ratio 20.63; 95 % CI 3.84, 110.77) in patients with CT were associated with a higher probability of lung cancer. Large nodule size and spiculated edge were associated with lung cancer on both CT and radiograph. Lung cancer-specific mortality was lower in patients with SPN than in those without SPN (1.73/1000 person-years, 95 % CI 1.08-2.88 vs. 2.15/1000 person-years, 95 % CI 1.25-3.96). CONCLUSIONS:The risk of lung cancer for patients with SPN is higher in clinical populations than in screening studies. Moreover, patients with SPN showed lower mortality than those without SPN. KEY POINTS:• Lung cancer risk is 8 % for SPN detected on routine radiographs. • Lung cancer risk is 12.4 % for SPN detected in routine chest CT. • Smoking, COPD, SPN diameter and edge were predictors of malignancy. • Lung cancer risk of SPN in routine practice seems higher than in screening.
journal_name
Eur Radioljournal_title
European radiologyauthors
Gómez-Sáez N,Hernández-Aguado I,Vilar J,González-Alvarez I,Lorente MF,Domingo ML,Valero MP,Parker LA,Lumbreras Bdoi
10.1007/s00330-015-3775-3subject
Has Abstractpub_date
2015-12-01 00:00:00pages
3518-27issue
12eissn
0938-7994issn
1432-1084pii
10.1007/s00330-015-3775-3journal_volume
25pub_type
杂志文章abstract:OBJECTIVES:To develop and evaluate the performance of a deep learning-based system for automatic patellar height measurements using knee radiographs. METHODS:The deep learning-based algorithm was developed with a data set consisting of 1018 left knee radiographs for the prediction of patellar height parameters, specif...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-020-06856-z
更新日期:2020-09-01 00:00:00
abstract::This is a report of clinical, CT and MRI findings in a patient with toxic spongiform leucoencephalopathy after heroin ingestion. The disease is observed in drug addicts who inhale pre-heated heroin. The clinical onset, which usually occurs some days or even longer after the last heroin consumption, is characterized by...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s003300050467
更新日期:1998-01-01 00:00:00
abstract:OBJECTIVES:Irreversible electroporation (IRE) is a new ablation technique that relies on high-voltage electrical pulses. This clinical study evaluates the pathological response of colorectal liver metastases (CRLM) treated with IRE and the clinical safety and feasibility. METHODS:Ten patients with resectable CRLM were...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-014-3259-x
更新日期:2014-10-01 00:00:00
abstract::Osteochondritis (osteochondrosis) dissecans (OCD) is a common condition in children, adolescents, and young adults. Describing OCD together with osteochondral fractures and epiphyseal ossification disturbances and considering these three conditions as one entity has caused much confusion. Age distribution and localiza...
journal_title:European radiology
pub_type: 杂志文章,评审
doi:10.1007/s003300050348
更新日期:1998-01-01 00:00:00
abstract::The technique of using an electrode as a lever to increase the distance between renal cell carcinoma (RCC) and bowel during CT-guided radiofrequency ablation (RFA) is described. CT-guided percutaneous RFA was performed in two patients with two RCCs, which were in close proximity to the adjacent bowel. A sterile drape ...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-007-0816-6
更新日期:2008-04-01 00:00:00
abstract:OBJECTIVES:To evaluate the performance of radiomic features extracted from high-resolution computed tomography (HRCT) for the differentiation between cholesteatoma and middle ear inflammation (MEI), and to investigate the impact of post-reconstruction harmonization and data resampling. METHODS:One hundred patients wer...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-020-07564-4
更新日期:2020-12-04 00:00:00
abstract:OBJECTIVES:Opportunistic screening for osteoporosis using computed tomography (CT) examinations that happen to visualise the spine can be used to identify patients with osteoporosis. We sought to verify the diagnostic performance of vertebral Hounsfield unit (HU) measurements on routine CT examinations for diagnosing o...
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doi:10.1007/s00330-014-3584-0
更新日期:2015-07-01 00:00:00
abstract:OBJECTIVES:This study was conducted in order to assess the performance of the Liver Imaging Reporting and Data System (LI-RADS) treatment response (TR) (LR-TR) categorization on gadoxetic acid-enhanced MRI (Gd-EOB-MRI) for detecting viable tumors in hepatocellular carcinoma (HCC) treated with locoregional treatment (LR...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-019-06623-9
更新日期:2020-05-01 00:00:00
abstract:OBJECTIVES:Various imaging methods have been evaluated regarding non-invasive differentiation of renal cell carcinoma (RCC) subtypes. Dual-energy computed tomography (DECT) allows iodine concentration (IC) analysis as a correlate of tissue perfusion. Microvascular density (MVD) in histopathology specimens is evaluated ...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-019-06298-2
更新日期:2020-01-01 00:00:00
abstract::The aim of this study was to describe the MRI findings and clinical observations in a fatigue stress fracture of the sacrum. In this retrospective study, 380 conscripts (53 women, 327 men; age range 18-29 years, mean age 20.7 years) who suffered from stress-related hip pain were studied with MRI of the pelvis. The fin...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-003-1989-2
更新日期:2004-03-01 00:00:00
abstract:OBJECTIVES:This prospective trial was performed to verify whether microwave ablation (MWA) in combination with chemotherapy could provide superior survival benefit compared with chemotherapy alone. MATERIALS AND METHODS:From March 1, 2015, to June 20, 2017, treatment-naïve patients with pathologically verified advance...
journal_title:European radiology
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1007/s00330-019-06613-x
更新日期:2020-05-01 00:00:00
abstract::This technical note describes the use of dynamic MRI in the diagnosis of groin herniations. A review of the anatomy of the groin is presented and 4 representative cases are described. This paper indicates that dynamic MRI can be used to confirm the diagnosis in patients with clinically evident groin herniations. ...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s003300050377
更新日期:1998-01-01 00:00:00
abstract:OBJECTIVES:To evaluate the diagnostic performance of arterial spin labelling perfusion weighted images (ASL-PWIs) to differentiate primary CNS lymphoma (PCNSL) from glioblastoma (GBM). METHODS:ASL-PWIs of pathologically confirmed PCNSL (n = 21) or GBM (n = 93) were analysed. For qualitative analysis, tumours were visu...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-018-5359-5
更新日期:2018-09-01 00:00:00
abstract::Tumors of the hand and wrist most commonly result from dystrophic lesions and hamartomas. Neoplastic lesions are rare. Imaging modalities are required for their detection and accurate location, careful assessment of the internal structure and borders, evaluation of the relation with surrounding tendons, nerves, and ve...
journal_title:European radiology
pub_type: 杂志文章,评审
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更新日期:2001-01-01 00:00:00
abstract:PURPOSE:3D-FLAIR sequences with delayed acquisition after contrast medium injection have demonstrated new insights into blood-labyrinthine barrier (BLB) abnormalities in various diseases. The aim of this study was to assess the BLB in patients referred with unilateral acute vestibular syndrome (UAVS). MATERIALS AND ME...
journal_title:European radiology
pub_type: 杂志文章,多中心研究
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更新日期:2019-06-01 00:00:00
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journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-014-3570-6
更新日期:2015-06-01 00:00:00
abstract::The purpose was to evaluate low-dose CT colonography without cathartic cleansing in terms of image quality, polyp visualization and patient acceptance. Sixty-one patients scheduled for colonoscopy started a low-fiber diet, lactulose and amidotrizoic-acid for fecal tagging 2 days prior to the CT scan (standard dose, 5....
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-007-0668-0
更新日期:2007-12-01 00:00:00
abstract::Severe thoracic sarcoidosis includes manifestations with significant clinical and functional impairment and a risk of mortality. Severe thoracic sarcoidosis can take on various clinical presentations and is associated with increased morbidity. The purpose of this article was to describe the CT findings in severe thora...
journal_title:European radiology
pub_type: 杂志文章,评审
doi:10.1007/s00330-004-2480-4
更新日期:2005-01-01 00:00:00
abstract:OBJECTIVE:To assess the heterogeneity of liver fat deposition with MR of the liver in type-2 diabetic (T2D) patients. METHODS:We enrolled 121 consecutive T2D patients. The reference standard was 3.0-T (1)H-MR spectroscopy. Hepatic steatosis was defined as liver fat content (LFC) ≥5.56 %. A triple-echo gradient-echo se...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-012-2468-4
更新日期:2012-10-01 00:00:00
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doi:10.1007/s00330-016-4525-x
更新日期:2017-05-01 00:00:00
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doi:10.1007/s00330-018-5665-y
更新日期:2019-03-01 00:00:00
abstract::This review provides an overview of structural magnetic resonance imaging and computed tomography findings of direct and indirect alcohol-related toxic effects on the brain. In addition to ethanol-related changes to the brain, this article will also describe imaging findings in the acute setting of methanol and ethyle...
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更新日期:2010-06-01 00:00:00
abstract::The objective of the study was to determine the values of Doppler resistance indices (RIs) in intrarenal arteries in healthy children. Color duplex Doppler sonography of intrarenal arteries was performed in 163 children and 58 adult patients, with the absence of clinical or laboratory pathologic changes of the urinary...
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pub_type: 杂志文章
doi:10.1007/s003300000466
更新日期:2000-01-01 00:00:00
abstract:OBJECTIVE:To demonstrate the non-inferiority of synthetic image (SI) mammography versus full-field digital mammography (FFDM) in breast tomosynthesis (DBT) examinations. METHODS:An observational, retrospective, single-centre, multireader blinded study was performed, using 2384 images to directly compare SI and FFDM ba...
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pub_type: 杂志文章,多中心研究
doi:10.1007/s00330-017-4991-9
更新日期:2018-02-01 00:00:00
abstract:OBJECTIVES:We wished to determine whether tumor morphology descriptors obtained from pretreatment magnetic resonance images and clinical variables could predict survival for glioblastoma patients. METHODS:A cohort of 404 glioblastoma patients (311 discoveries and 93 validations) was used in the study. Pretreatment vol...
journal_title:European radiology
pub_type: 杂志文章,多中心研究
doi:10.1007/s00330-018-5758-7
更新日期:2019-04-01 00:00:00
abstract::Lesion area measurement in multiple sclerosis (MS) is one of the key points in evaluating the natural history and in monitoring the efficacy of treatments. This study was performed to check the intra- and inter-observer agreement variability of a locally developed Growing Region Segmentation Software (GRES), comparing...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s003300100978
更新日期:2002-04-01 00:00:00
abstract:OBJECTIVES:To evaluate the relationship between contrast-enhanced (CE) ultrasound Liver Reporting and Data System (LI-RADS) classification of combined hepatocellular-cholangiocarcinoma (cHCC-CCA) and their histopathological component predominance, and to determine if the CEUS LI-RADS category can be used to predict the...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-020-07656-1
更新日期:2021-01-25 00:00:00
abstract:OBJECTIVES:To utilize a deep learning model for automatic detection of abnormalities in chest CT images from COVID-19 patients and compare its quantitative determination performance with radiological residents. METHODS:A deep learning algorithm consisted of lesion detection, segmentation, and location was trained and ...
journal_title:European radiology
pub_type: 杂志文章,多中心研究
doi:10.1007/s00330-020-07044-9
更新日期:2020-12-01 00:00:00
abstract::Our objective was to evaluate, in a routine clinical setting, the role of spiral CT as a second procedure in patients with clinically suspected pulmonary embolism (PE) and abnormal perfusion scan. We prospectively studied the role of spiral CT in 279 patients suspected of PE. All patients started their diagnostic algo...
journal_title:European radiology
pub_type: 杂志文章,多中心研究
doi:10.1007/s00330-002-1709-3
更新日期:2003-07-01 00:00:00
abstract::The application of image registration and subtraction to detect change in multiple sclerosis (MS) disease burden on serial MR scans benefits from the use of isotropic voxels. An optimised 3D fast fluid-attenuated inversion recovery (FLAIR) sequence with 1.2- and 1.8-mm cubic voxels was compared with a 2D T2 SE sequenc...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-001-1170-8
更新日期:2002-03-01 00:00:00