Abstract:
OBJECTIVES:To describe a randomized controlled trial (RCT) of digital breast tomosynthesis including synthesized two-dimensional mammograms (DBT) versus digital mammography (DM) in a population-based screening program for breast cancer and to compare selected secondary screening outcomes for the two techniques. METHODS:This RCT, performed in Bergen as part of BreastScreen Norway, was approved by the Regional Committees for Medical Health Research Ethics. All screening attendees in Bergen were invited to participate, of which 89% (14,274/15,976) concented during the first year, and were randomized to DBT (n = 7155) or DM (n = 7119). Secondary screening outcomes were stratified by mammographic density and compared using two-sample t-tests, chi-square tests, ANOVA, negative binomial regression and tests of proportions (z tests). RESULTS:Mean reading time was 1 min 11 s for DBT and 41 s for DM (p < 0.01). Mean time spent at consensus was 3 min 12 s for DBT and 2 min 12 s for DM (p < 0.01), while the rate of cases discussed at consensus was 6.4% and 7.4%, respectively for DBT and DM (p = 0.03). The recall rate was 3.0% for DBT and 3.6% for DM (p = 0.03). For women with non-dense breasts, recall rate was 2.2% for DBT versus 3.4% for DM (p = 0.04). The rate did not differ for women with dense breasts (3.6% for both). Mean glandular dose per examination was 2.96 mGy for DBT and 2.95 mGy for DM (p = 0.433). CONCLUSIONS:Interim analysis of a screening RCT showed that DBT took longer to read than DM, but had significantly lower recall rate than DM. We found no differences in radiation dose between the two techniques. KEY POINTS:• In this RCT, DBT was associated with longer interpretation time than DM • Recall rates were lower for DBT than for DM • Mean glandular radiation dose did not differ between DBT and DM.
journal_name
Eur Radioljournal_title
European radiologyauthors
Aase HS,Holen ÅS,Pedersen K,Houssami N,Haldorsen IS,Sebuødegård S,Hanestad B,Hofvind Sdoi
10.1007/s00330-018-5690-xsubject
Has Abstractpub_date
2019-03-01 00:00:00pages
1175-1186issue
3eissn
0938-7994issn
1432-1084pii
10.1007/s00330-018-5690-xjournal_volume
29pub_type
杂志文章,多中心研究,随机对照试验abstract::The development and progression of a hepatocellular carcinoma (HCC) in a chronically diseased liver, i.e., the carcinogenesis, comprise a multistep and long-term process. Morphologically, this process is associated with the presence of distinct nodular lesions in the liver that are called 'preneoplastic lesions.' Thes...
journal_title:European radiology
pub_type: 杂志文章,评审
doi:10.1007/s00330-007-0602-5
更新日期:2007-10-01 00:00:00
abstract::Acute liver failure (ALF)-related encephalopathy was previously characterized by MR spectroscopy of single voxels containing both grey and white matter brain tissue. Quantitative multivoxel MRS was used here to compare grey and white matter brain tissue concentrations of glutamate/glutamine (Glx) and lactate in ALF an...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-008-1049-z
更新日期:2008-11-01 00:00:00
abstract::Magnetic resonance imaging can be used to measure the muscle volume of a given muscle or muscle group. The purpose of this study was to determine both the intra- and inter-observer variation of the manually outlined volume of the extensor muscles (tibialis anterior, extensor digitorum longus and extensor hallucis long...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-002-1334-1
更新日期:2002-12-01 00:00:00
abstract:OBJECTIVES:Diagnostic accuracy of conventional coronary CT angiography (CCTAconv) may be compromised by blooming artifacts from calcifications or stents. Blooming artifacts may be reduced by subtraction coronary CT angiography (CCTAsub) in which non-contrast and contrast CT data sets are subtracted digitally. We tested...
journal_title:European radiology
pub_type: 杂志文章,多中心研究
doi:10.1007/s00330-018-5418-y
更新日期:2018-10-01 00:00:00
abstract::Spinal vascular malformations are rare diseases that consist of true inborn cavernomas and arteriovenous malformations (including perimedullary fistulae, glomerular and juvenile AVMs) and presumably acquired dural arteriovenous fistulae. This review article gives an overview of the imaging features both on MRI and ang...
journal_title:European radiology
pub_type: 杂志文章,评审
doi:10.1007/s00330-004-2510-2
更新日期:2005-02-01 00:00:00
abstract::Varicocele can be very easily diagnosed by physical examination and subsequently treated when it is painful or associated with testicular hypotrophy. However, palpability of the spermatic vein and reflux in low grade or even questionable varicoceles can be difficult to assess without imaging modalities. This can be a ...
journal_title:European radiology
pub_type: 杂志文章,评审
doi:10.1007/s003300050706
更新日期:1999-01-01 00:00:00
abstract::Gadoxetic acid-enhanced magnetic resonance imaging (MRI) plays important roles in diagnosis of hepatic lesions because of its superiority in the detectability of small lesions, its differentiation ability, and its utility for the early diagnosis of hepatocellular carcinoma (HCC). In HCC, expression of organic anion tr...
journal_title:European radiology
pub_type: 杂志文章,评审
doi:10.1007/s00330-020-06687-y
更新日期:2020-06-01 00:00:00
abstract:OBJECTIVE:To investigate the feasibility and clinical efficacy of ultrasound (US)-guided diffused optical tomography (DOT) in differentiating malignant breast lesions from benign lesions. MATERIAL AND METHODS:From October 2007 to August 2008, 198 women with 214 lesions scheduled for open biopsy were included in this s...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-009-1551-y
更新日期:2010-02-01 00:00:00
abstract::The arrival of new surgical transplantation techniques, such as split living donor or auxiliary liver transplantation, have increased the incidence of vascular and biliary complications. The causes, symptoms, and diagnostic modalities of arterial, portal caval, and biliary complications are detailed. Interventional te...
journal_title:European radiology
pub_type: 杂志文章,评审
doi:10.1007/s00330-003-2196-x
更新日期:2004-03-01 00:00:00
abstract:OBJECTIVE:To design clear guidelines for the staging and follow-up of patients with uterine cervical cancer, and to provide the radiologist with a framework for use in multidisciplinary conferences. METHODS:Guidelines for uterine cervical cancer staging and follow-up were defined by the female imaging subcommittee of ...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-010-1998-x
更新日期:2011-05-01 00:00:00
abstract::The appearances of knee injuries on MR imaging are less well documented in children than adults. Some patterns of injury are shared by both groups of patients, e. g. meniscal damage. The frequency of specific injuries may differ, e. g. anterior cruciate ligament (ACL) tear. Congenital abnormality, coexistent pathology...
journal_title:European radiology
pub_type: 杂志文章,评审
doi:10.1007/s003300050284
更新日期:1997-01-01 00:00:00
abstract::We report the case of a 32-year-old female presenting with two pulmonary artery false aneurysms of mycotic origin. Considering the natural history and potential complications, we treated the patient by intrasaccular embolization with steel coils. No complication occurred. ...
journal_title:European radiology
pub_type: 杂志文章,评审
doi:10.1007/s003300050130
更新日期:1997-01-01 00:00:00
abstract:OBJECTIVE:To investigate comparative effectiveness of drug-eluting bead transarterial chemoembolization (DEB-TACE) versus Yttrium-90 (90Y)-radioembolization for hepatocellular carcinoma (HCC). METHODS:Studies comparing conventional (c)TACE versus 90Y-radioembolization or DEB-TACE for HCC treatment were identified usin...
journal_title:European radiology
pub_type: 杂志文章,meta分析
doi:10.1007/s00330-016-4548-3
更新日期:2017-05-01 00:00:00
abstract:OBJECTIVES:To evaluate the frequency of diagnosis of high-risk lesions at MRI-guided vacuum-assisted breast biopsy (MRgVABB) and to determine whether underestimation may be predicted. METHODS:Retrospective review of the medical records of 161 patients who underwent MRgVABB was performed. The underestimation rate was d...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-010-1949-6
更新日期:2011-03-01 00:00:00
abstract:OBJECTIVE:To assess the value of time-intensity curves obtained after sulphur hefluoride-filled microbubble contrast agent injection to discriminate responders from non-responders among patients with Crohn's disease (CD). METHODS:Forty-three patients (29 male and 14 female; mean age ± SD, 48.5 ± 17.17 years) with init...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-012-2754-1
更新日期:2013-06-01 00:00:00
abstract:OBJECTIVES:To assess the coronary atherosclerosis profile by coronary computed tomography angiography (CTA) in patients with end-stage liver disease (ESLD) due to alcohol-related liver disease (ARLD) evaluated for liver transplantation (LT), in a retrospective matched case-controlled cohort study. METHODS:One hundred ...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-020-07037-8
更新日期:2021-01-01 00:00:00
abstract:OBJECTIVES:The purpose of this study was to retrospectively assess the incidence of bowel wall oedema on computed tomography (CT) in patients with renal cell carcinoma (RCC) treated with sunitinib, and to investigate its association with diarrhoea. METHODS:We conducted a retrospective analysis of all RCC patients trea...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-014-3389-1
更新日期:2015-02-01 00:00:00
abstract::Magnetic resonance angiography (MRA) has become an imaging modality which comprises various techniques based on two concepts: methods relying on the natural flow effects, the time-of-flight and phase-contrast technique, either in two- or three-dimensional acquisition mode, and the more recently developed contrast-enha...
journal_title:European radiology
pub_type: 杂志文章,评审
doi:10.1007/s003300050834
更新日期:1999-01-01 00:00:00
abstract::Aneurysmal bone cysts (ABC) are rare, benign, but locally destructive bone tumors. They occur in the spine in 14% of cases, but only 2% are found in the cervical spine. This case report presents a 16-year-old female with an expansive aneurysmatic bone cyst with extensive bone destruction and instability in the cervica...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-008-0944-7
更新日期:2008-10-01 00:00:00
abstract::The purpose of this study was to evaluate the diagnostic utility of sonoelastography in differentiating benign from malignant non-palpable breast lesions. A total of 293 BI-RADS 3-5 (Breast Imaging Reporting And Data System) impalpable breast lesions in 278 women was evaluated with B-mode ultrasound (US) and subsequen...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-008-1032-8
更新日期:2008-11-01 00:00:00
abstract:OBJECTIVES:To investigate the impact of mesorectal fat area (MFA) on oncologic outcomes in patients with mid-to-lower rectal cancer who received curative-intent surgery. METHODS:Patients with mid-to-lower rectal cancer who underwent preoperative abdominopelvic computed tomography (CT) and curative-intent surgery in 20...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-018-5723-5
更新日期:2019-03-01 00:00:00
abstract::The aim of this study was to evaluate the radiation dose given by semicoronal CT of the sacroiliac joints (SIJs) in comparison with axial CT and conventional radiography. The total effective radiation doses given by serial contiguous semicoronal and axial CT, using 5-mm slices, 120 kV and 330 mAs, were determined by m...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-001-1297-7
更新日期:2002-11-01 00:00:00
abstract:OBJECTIVE:This study determined the effect of dose reduction and kernel selection on quantifying emphysema using low-dose computed tomography (LDCT) and evaluated the efficiency of a deep learning-based kernel conversion technique in normalizing kernels for emphysema quantification. METHODS:A sample of 131 participant...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-020-07020-3
更新日期:2020-12-01 00:00:00
abstract::The safety of the non-ionic contrast medium iopentol (Imagopaque, Nycomed Imaging AS, Oslo, Norway) when used in cerebral angiography and aortic arch angiography, was the focus of this investigation. Overall quality of visualization and changes in heart rate and blood pressure were, however, also assessed. In total, 3...
journal_title:European radiology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1007/pl00006884
更新日期:1997-01-01 00:00:00
abstract::A single center's procedural and follow-up results of radiological chest port placement in pediatric oncology patients are presented. Between July 2002 and December 2003, 37 children (20 boys, 17 girls; age range, 4 months to 16 years; mean 6.7 years) underwent chest port placement. All patients received only one port...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-004-2380-7
更新日期:2004-11-01 00:00:00
abstract:OBJECTIVES:This study was conducted in order to evaluate whether enhancement types on preoperative MRI can reflect prognostic factors and surgical outcomes in invasive breast cancer. METHODS:Among 484 consecutive patients who underwent preoperative breast MRI from October 2014 to July 2017 for biopsy-proven breast can...
journal_title:European radiology
pub_type: 杂志文章,多中心研究
doi:10.1007/s00330-019-06236-2
更新日期:2019-12-01 00:00:00
abstract:OBJECTIVE:Assessing the advantage of x-ray dark-field contrast over x-ray transmission contrast in radiography for the detection of developing radiation-induced lung damage in mice. METHODS:Two groups of female C57BL/6 mice (irradiated and control) were imaged obtaining both contrasts monthly for 28 weeks post irradia...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-020-07459-4
更新日期:2020-11-19 00:00:00
abstract:OBJECTIVE:To investigate the prognostic significance of T1 mapping using T1 long and short in hypertrophic cardiomyopathy (HCM) patients. METHODS:A total of 263 consecutive patients with HCM referred for cardiovascular magnetic resonance (CMR) imaging were enrolled in this study. The imaging protocol consisted of cine...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-020-07650-7
更新日期:2021-01-15 00:00:00
abstract:OBJECTIVES:To explain the technical principles of and differences between commercially available iterative reconstruction (IR) algorithms for computed tomography (CT) in non-mathematical terms for radiologists and clinicians. METHODS:Technical details of the different proprietary IR techniques were distilled from avai...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-012-2765-y
更新日期:2013-06-01 00:00:00
abstract:KEY POINT:• The term "pericolic" is wrongly used to describe an abscess adjacent to the colon in patients with acute diverticulitis. We explain why the proper term is the word "paracolic." ...
journal_title:European radiology
pub_type: 信件
doi:10.1007/s00330-018-5827-y
更新日期:2019-08-01 00:00:00