Abstract:
:The development and progression of a hepatocellular carcinoma (HCC) in a chronically diseased liver, i.e., the carcinogenesis, comprise a multistep and long-term process. Morphologically, this process is associated with the presence of distinct nodular lesions in the liver that are called 'preneoplastic lesions.' These preneoplastic lesions are associated with and can precede the growth and progression of well-differentiated HCCs . The characterization of nodular lesions and demonstration of the multistep development of HCC in the cirrhotic liver by imaging modalities represent a challenging issue. The arterial hypervascular supply, depicted by different dynamic studies, represents a fundamental radiological criterion for the diagnosis of HCC in cirrhosis. Magnetic resonance (MR) imaging performed with tissue-specific contrast media can help to investigate the "grey area" of carcinogenesis, in which significant histological changes are already present without any imaging evidence of neoangiogenesis. The purpose of this review is to provide information on the properties of tissue-specific MR contrast agents and on their usefulness in the demonstration of the pathologic changes that take place at the level of the biliary and reticuloendothelial systems during the carcinogenetic process in liver cirrhosis.
journal_name
Eur Radioljournal_title
European radiologyauthors
Bartolozzi C,Crocetti L,Lencioni R,Cioni D,Della Pina C,Campani Ddoi
10.1007/s00330-007-0602-5subject
Has Abstractpub_date
2007-10-01 00:00:00pages
2519-30issue
10eissn
0938-7994issn
1432-1084journal_volume
17pub_type
杂志文章,评审abstract::Vertebral fractures are the hallmark of osteoporosis and are associated with increased morbility and mortality. Because a majority of vertebral fractures often occur in absence of specific trauma and are asymptomatic, their identification is radiographic. The two most widely used methods to determine the severity of v...
journal_title:European radiology
pub_type: 杂志文章,评审
doi:10.1007/s00330-008-0899-8
更新日期:2008-07-01 00:00:00
abstract::The usefulness of diffusion-weighted magnetic resonance (MR) imaging (DWI) for differentiating central lung cancer from postobstructive lobar collapse (POC) was investigated. Thirty-three cases suspected of lung cancer and POC on chest bolus computed tomography (CT) underwent thoracic MR imaging examinations. MR exami...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-008-1134-3
更新日期:2009-02-01 00:00:00
abstract::The aim of this study was to assess whether magnetic resonance imaging could predict the outcome of attempted vaginal delivery in a group of pregnant women whose parturition had to be induced by oxytocin. The signal intensity and morphology alterations in the cervix of 21 full-term pregnant women were analyzed before ...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s003300051001
更新日期:2000-01-01 00:00:00
abstract::We report a case of neurilemoma arising from the renal capsule. Renal neurilemoma is an especially rare tumor, with only 15 cases previously reported. We attempted to correlate MR findings with microscopic components of the tumor. On T2-weighted images the solid part of the tumor was heterogeneous hyperintense. The MR...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s003300000767
更新日期:2001-01-01 00:00:00
abstract:OBJECTIVES:To assess whether with recent MR technology current patient preparation literature recommendations for female pelvic MRI are still valid and how they are influencing the position of the female pelvic organs, image quality, and diagnostic confidence. METHODS:This prospective study was performed in two centre...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-020-06869-8
更新日期:2020-10-01 00:00:00
abstract:OBJECTIVES:To evaluate the quantitative parameters obtained from dynamic MR T2*-weighted images as predictors of survival taking into consideration the biasing effects of other survival-related covariates. METHODS:Thirty-nine patients (60 ± 14 years; survival 267 ± 191 days) with high-grade gliomas (8 grade III, 31 gr...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-013-2967-y
更新日期:2013-12-01 00:00:00
abstract:OBJECTIVES:To investigate whether the addition of nitroglycerine to transcatheter arterial (chemo)embolization (TAE/TACE) can increase the delivery and effectiveness of TAE/TACE in patients with hepatocellular carcinoma (HCC) by dual-energy CT. METHODS:HCC patients (BCLC stage A or B) were randomized to (n = 51) or no...
journal_title:European radiology
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00330-012-2484-4
更新日期:2012-10-01 00:00:00
abstract:OBJECTIVES:To evaluate effects of a vascular-disrupting agent on rodent tumour models. METHODS:Twenty rats with liver rhabdomyosarcomas received ZD6126 intravenously at 20 mg/kg, and 10 vehicle-treated rats were used as controls. Multiple sequences, including diffusion-weighted imaging (DWI) and dynamic contrast-enhan...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-010-1743-5
更新日期:2010-08-01 00:00:00
abstract:OBJECTIVES:To evaluate the potential value of apparent diffusion coefficient (ADC) measurement in the assessment of cervical cancer. METHODS:One hundred twelve patients with cervical cancer and 67 control subjects underwent diffusion-weighted imaging (DWI) in addition to routine MR imaging at 3.0-T MRI before therapy....
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-012-2681-1
更新日期:2013-04-01 00:00:00
abstract::This review provides an overview of structural magnetic resonance imaging and computed tomography findings of direct and indirect alcohol-related toxic effects on the brain. In addition to ethanol-related changes to the brain, this article will also describe imaging findings in the acute setting of methanol and ethyle...
journal_title:European radiology
pub_type: 杂志文章,评审
doi:10.1007/s00330-009-1668-z
更新日期:2010-06-01 00:00:00
abstract:OBJECTIVE:To determine the possible influence of segmentation margin on each step (feature reproducibility, selection, and classification) of the machine learning (ML)-based high-dimensional quantitative computed tomography (CT) texture analysis (qCT-TA) of renal clear cell carcinomas (RcCCs). MATERIALS AND METHODS:Fo...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-019-6003-8
更新日期:2019-09-01 00:00:00
abstract:OBJECTIVE:This study aims to establish and validate a radiomics nomogram based on contrast-enhanced spectral mammography (CESM) for prediction of axillary lymph node (ALN) metastasis in breast cancer. METHODS:This retrospective study included 394 patients with breast cancer who underwent CESM examination in two hospit...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-020-07016-z
更新日期:2020-12-01 00:00:00
abstract::There is little published long-term survival data for patients with colorectal liver metastases treated with radiofrequency ablation (RFA). We present a multivariate analysis of 5-year survival in 309 patients (198 male, aged 64 (24-92)) treated at 617 sessions. Our standard protocol used internally cooled electrodes ...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-008-1258-5
更新日期:2009-05-01 00:00:00
abstract:OBJECTIVES:The purpose of this study was to investigate the association of relaxation-compensated chemical exchange saturation transfer (CEST) MRI with overall survival (OS) and progression-free survival (PFS) in newly diagnosed high-grade glioma (HGG) patients. METHODS:Twenty-six patients with newly diagnosed high-gr...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-019-06066-2
更新日期:2019-09-01 00:00:00
abstract:OBJECTIVES:Pre-therapeutic prediction of outcome is important for clinicians and patients in determining whether selective internal radiation therapy (SIRT) is indicated for hepatic metastases of colorectal cancer (CRC). METHODS:Pre-therapeutic characteristics of 100 patients with colorectal liver metastases (CRLM) tr...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-015-3658-7
更新日期:2015-09-01 00:00:00
abstract:OBJECTIVES:To develop an MRI enterography global score (MEGS) of Crohn's disease (CD) activity compared with a reference standard of faecal calprotectin (fC), C-reactive protein (CRP) and Harvey-Bradshaw index (HBI). METHODS:Calprotectin, CRP and HBI were prospectively recorded for 71 patients (median age 33, male 35)...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-013-3010-z
更新日期:2014-02-01 00:00:00
abstract:OBJECTIVES:In dual-source CT, dual-energy (DE) performance is affected by various X-ray tube voltage combinations with and without tin filter (Sn). The purpose of this study was to assess the utility of the 80/150 Sn kV voltage combination in terms of image artefact and radiation dose for DECT gout protocol, compared w...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-018-5622-9
更新日期:2019-03-01 00:00:00
abstract::Preoperative MRI of the breasts has been proven to be the most sensitive imaging modality in the detection of multifocal or multicentric tumor manifestations as well as simultaneous contralateral breast cancer. The aim of the presented retrospective study was to evaluate the benefit of preoperative MRI for patients wi...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-004-2351-z
更新日期:2004-10-01 00:00:00
abstract:OBJECTIVES:To compare the value of functional future liver remnant (functFLR) to established clinical and imaging variables in prediction of post-hepatectomy liver failure (PHLF) after major liver resection. METHODS:This retrospective, cross-sectional study included 62 patients, who underwent gadoxetic acid enhanced M...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-018-5487-y
更新日期:2018-11-01 00:00:00
abstract:PURPOSE:To evaluate the prognosis of "strict" high-risk nodules (small hepatocellular nodules detected only in the hepatobiliary phase of initial Gd-EOB-DTPA-enhanced MR examination) in patients with cirrhosis or chronic hepatitis. METHODS AND MATERIALS:The study included thirty-three patients with 60 "strict" high-ri...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-014-3293-8
更新日期:2014-10-01 00:00:00
abstract:OBJECTIVES:To evaluate whole-body MRI with diffusion-weighted sequence (WB-DWI/MRI) for staging and assessing operability compared with CT and FDG-PET/CT in patients with suspected ovarian cancer. METHODS:Thirty-two patients underwent 3-T WB-DWI/MRI, (18) F-fluorodeoxyglucose positron emission tomography/computed tomo...
journal_title:European radiology
pub_type: 临床试验,杂志文章
doi:10.1007/s00330-013-3083-8
更新日期:2014-04-01 00:00:00
abstract::This Editorial Comment refers to the article "Citation Bias in Imaging Research: Are studies with higher diagnostic accuracy estimates cited more often?" by Frank RA, Sharifabadi AD, Salameh JP et al, Eur Radiol. 2018 Nov 15. https://doi.org/10.1007/s00330-018-5801-8 [1]. ...
journal_title:European radiology
pub_type: 评论,社论
doi:10.1007/s00330-018-5974-1
更新日期:2019-04-01 00:00:00
abstract:OBJECTIVES:To determine the feasibility of MRI texture analysis as a method of quantifying subchondral bone architecture in knee osteoarthritis (OA). METHODS:Asymptomatic subjects aged 20-30 (group 1, n = 10), symptomatic patients aged 40-50 (group 2, n = 10) and patients scheduled for knee replacement aged 55-85 (gro...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-015-4142-0
更新日期:2016-09-01 00:00:00
abstract::The aim of this study was to assess the capability of a 3D isotropic MRI T2-weighted sequence (3D T2 ISO) in the depiction of changes of neurovascular bundles (NVBs) after bilateral nerve-sparing radical retropubic prostatectomy (RRP). Furthermore, our aim was also to introduce a new MRI classification score of the NV...
journal_title:European radiology
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00330-008-1102-y
更新日期:2009-01-01 00:00:00
abstract:OBJECTIVES:To correlate hepatic and splenic CT perfusion parameters with hepatic venous pressure gradient (HVPG) measurements in patients with cirrhosis. METHODS:Twenty-one patients with cirrhosis (males, 17; females, 4; mean ± SD age, 57 ± 7 years) underwent hepatic and splenic perfusion CT on a 320-detector row volu...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-017-4788-x
更新日期:2017-10-01 00:00:00
abstract::Although the predominant form of tuberculosis is pulmonary disease, an increasing number of cases with extra-pulmonary involvement have been reported. The diagnosis of extra-pulmonary tuberculosis is often difficult because of its protean clinical manifestations and non-specific laboratory findings. Abdominal lymph no...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-003-1943-3
更新日期:2004-04-01 00:00:00
abstract::We assessed the effect of intra-coronary attenuation on diagnostic accuracy using 64-slice computed tomography coronary angiography (CT-CA). We enrolled 170 patients with suspected coronary artery disease who underwent conventional coronary angiography (CA) and 64-slice CT-CA (100 ml of Iomeprol 400 mg I/ml at 4 ml/s)...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-007-0773-0
更新日期:2008-03-01 00:00:00
abstract::To investigate the influence of age, sex and spinal level on perfusion parameters of normal lumbar bone marrow with dynamic contrast-enhanced MRI (DCE MRI). Sixty-seven subjects referred for evaluation of low back pain or sciatica underwent DCE MRI of the lumbar spine. After subtraction of dynamic images, a region of ...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-008-0943-8
更新日期:2008-09-01 00:00:00
abstract:OBJECTIVES:To investigate the feasibility of low-concentration contrast media (LC-CM) in cerebral and cervical dual-energy CT angiography (DE-CTA) using an advanced monoenergetic (Mono+) reconstruction technique. METHODS:Sixty-five consecutive patients prospectively selected to undergo cerebral and cervical DE-CTA wer...
journal_title:European radiology
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00330-018-5407-1
更新日期:2018-10-01 00:00:00
abstract:OBJECTIVE:To evaluate the risk factors affecting early diffuse recurrence within 1 year of percutaneous ultrasound-guided radiofrequency ablation (RFA) for hepatocellular carcinoma (HCC). METHODS:Out of 146 patients who received transcatheter arterial chemoembolisation (TACE) for treatment of recurrent HCC after percu...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-012-2561-8
更新日期:2013-01-01 00:00:00