Cystic angiomatosis with splenic involvement: unusual MRI findings.

Abstract:

:Cystic angiomatosis is a rare disorder with a poor prognosis. We describe a case of a 33-year-old woman who presented with longstanding bone pain, hemolytic anemia, and an enlarged spleen. Radiologically, multiple osseous lesions with a mixed pattern of lytic and sclerotic areas were seen within the shoulders, spine, and pelvis. On CT and MRI of the abdomen, the spleen was markedly enlarged, with internal hyperdense foci on non-contrast CT scan, corresponding to low signal intensity areas on all MR pulse sequences. After administration of contrast, a mottled enhancement pattern throughout the entire spleen was seen both on CT and MRI. Cystic angiomatosis was proven by histological analysis of a biopsy specimen of an involved vertebra and histopathological examination of the spleen after subsequent splenectomy. This is the first report of a patient with disseminated cystic angiomatosis with splenic involvement in which the MRI features differ from the previous reports. Instead of the usual pattern consisting of multiple well-defined cystic lesions, a diffuse involvement replacing the entire spleen, with heterogeneous signal intensities on T2-weighted images and heterogeneous enhancement pattern, was seen in our patient.

journal_name

Eur Radiol

journal_title

European radiology

authors

Vanhoenacker FM,Schepper AM,Raeve H,Berneman Z

doi

10.1007/s00330-002-1805-4

subject

Has Abstract

pub_date

2003-12-01 00:00:00

pages

L35-9

eissn

0938-7994

issn

1432-1084

journal_volume

13 Suppl 6

pub_type

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