The effect of magnesium on glycolysis of permeabilized Ehrlich ascites tumor cells.

abstract：:Peptide biosynthesis within a neuron involves several steps occurring at the soma and during its travel to the nerve terminal, where it accumulates to be released under stimulatory conditions. We have measured hypothalamic TRH and TRH mRNA during ontogeny and circadian cycle and observed that TRH mRNA variations are m...

journal_title：Biochemical and biophysical research communications

authors： Covarrubias L,Uribe RM,Méndez M,Charli JL,Joseph-Bravo P

更新日期：1988-02-29 00:00:00

abstract：:The recently detected Rieske iron-sulfur center in the membrane of the thermoacidophilic archaeon Sulfolobus acidocaldarius (Anemüller et al., 1993, FEBS Lett. 318, 61-64) was further characterized by EPR spectroscopy, coupled to redox-potentiometry and functional studies. The reduction potential is pH-dependent above...

journal_title：Biochemical and biophysical research communications

authors： Anemüller S,Schmidt CL,Schäfer G,Bill E,Trautwein AX,Teixeira M

更新日期：1994-07-15 00:00:00

abstract：:This study examines the influence of insoluble matrix components of glioma (astrocytoma) cells on LPS-mediated inducible nitric oxide (NO)/NO synthase (iNOS) induction in microglia cells. Insoluble matrix components prepared from C6 rat glioma cells strongly suppressed iNOS induction and subsequent NO release induced ...

journal_title：Biochemical and biophysical research communications

authors： Kim YJ,Hwang SY,Han IO

更新日期：2006-09-01 00:00:00

abstract：:Dexamethasone (DEX) induces apoptosis in lymphocytes, while protecting some cancer cells from apoptosis, by a poorly understood mechanism. In this study, we examined the potential role of the forkhead transcription factor (FOXO3A) in DEX-induced apoptosis. Unphosphorylated FOXO3A, the active form of FOXO3A, can transl...

journal_title：Biochemical and biophysical research communications

authors： Ma J,Xie Y,Shi Y,Qin W,Zhao B,Jin Y

更新日期：2008-12-19 00:00:00

abstract：:Although cervical cancer screening in the UK has led to reductions in the incidence of invasive disease, this programme remains flawed. We set out to examine the potential of infrared (IR) microspectroscopy to allow the profiling of cellular biochemical constituents associated with disease progression. Attenuated tota...

journal_title：Biochemical and biophysical research communications

authors： Walsh MJ,Singh MN,Pollock HM,Cooper LJ,German MJ,Stringfellow HF,Fullwood NJ,Paraskevaidis E,Martin-Hirsch PL,Martin FL

更新日期：2007-01-05 00:00:00

abstract：:The RNase gene superfamily combines functionally divergent proteins which share statistically significant sequence similarity. Known members assigned to this family include secretory and nonsecretory RNases; angiogenin; eosinophil cationic protein; eosinophil-derived neurotoxin; sialic-acid binding lectin and anti-tum...

journal_title：Biochemical and biophysical research communications

authors： Klenova EM,Botezato I,Laudet V,Goodwin GH,Wallace JC,Lobanenkov VV

更新日期：1992-05-29 00:00:00

abstract：:Under nitrosative stressed condition intracellular GSNO accumulation is common to all cell types. Conserved NADH-dependent GSNO reductase was reported previously as an important cellular protective measure against this. In spite of the constitutive nature of the enzyme, we observed in vivo inactivation of two importan...

journal_title：Biochemical and biophysical research communications

authors： Sahoo R,Sengupta R,Ghosh S

更新日期：2003-03-21 00:00:00

abstract：:The regulatory role of long non-coding RNAs (lncRNAs) in various biological functions has been demonstrated. However, their role in fat deposition and lipid metabolism in pigs remains less understood. To explore the expression profile of lncRNAs in Jinhua and Landrace pigs, we investigated the expression levels of lnc...

journal_title：Biochemical and biophysical research communications

authors： Miao Z,Wang S,Zhang J,Wei P,Guo L,Liu D,Wang Y,Shi M

更新日期：2018-11-30 00:00:00

abstract：:Mutations in mitochondrial DNA are one of the important causes of hearing loss. We report here the clinical, genetic, and molecular characterization of two Han Chinese pedigrees with maternally transmitted aminoglycoside-induced and nonsyndromic bilateral hearing loss. Clinical evaluation revealed the wide range of se...

journal_title：Biochemical and biophysical research communications

authors： Yuan H,Chen J,Liu X,Cheng J,Wang X,Yang L,Yang S,Cao J,Kang D,Dai P,Zhai S,Han D,Young WY,Guan MX

更新日期：2007-10-12 00:00:00

abstract：:Previous studies have extensively demonstrated the effect of endothelin-1 (ET-1), angiotensin II (Ang II), and TGF-β1 on the stimulation of collagen type I expression in cardiac myofibroblasts. However, the role of pro-remodeling peptides in the transcriptional regulation of the collagen promoter remains unclear. Thus...

journal_title：Biochemical and biophysical research communications

authors： Kisling A,Katwa LC

更新日期：2019-08-06 00:00:00

abstract：:IL-1 alpha cDNA clone was isolated from a T cell line infected by the human T lymphotropic retrovirus type-I (HTLV-I/ATLV). We found significant amounts of mRNA hybridizing to IL-1 alpha cDNA not only in HTLV-I-transformed T cells but also in Epstein-Barr Virus-transformed B cells. A part of IL-2 receptor inducing act...

journal_title：Biochemical and biophysical research communications

authors： Noma T,Nakamura T,Maeda M,Okada M,Taniguchi Y,Tagaya Y,Yaoita Y,Yodoi J,Honjo T

更新日期：1986-08-29 00:00:00

abstract：:Mesoporous silica nanoparticles (MSNPs) of a small diameter were loaded with the anticancer drug temozolomide (TMZ), coated with polydopamine (PDA), and conjugated with Asn-Gly-Arg (NGR) for use in the treatment of glioma. The accumulation of NGR-MSNPs in C6 cells was shown to be higher than that of unmodified MSNPs. ...

journal_title：Biochemical and biophysical research communications

authors： Zhang P,Tang M,Huang Q,Zhao G,Huang N,Zhang X,Tan Y,Cheng Y

更新日期：2019-02-05 00:00:00

abstract：:The peroxisome proliferator-activated receptor gamma, co-activator 1 alpha(PGC1α) effectively induced the biosynthesis of the mitochondria and the energy metabolism, and also regulated the muscle fiber-type shift. Overexpression of PGC1α gene in mice led to higher oxidative muscle fiber composition in muscle. However,...

journal_title：Biochemical and biophysical research communications

authors： Ying F,Zhang L,Bu G,Xiong Y,Zuo B

更新日期：2016-11-25 00:00:00

abstract：:Follistatin, activin and inhibin proteins are produced by granulosa cells, but the mechanisms controlling their production remain unclear. Here, we examined how the protein kinase A (PKA) and protein kinase C (PKC) pathways act and interact to regulate production of these proteins. Granulosa cells from immature rats w...

journal_title：Biochemical and biophysical research communications

authors： Miyanaga K,Erickson GF,DePaolo LV,Ling N,Shimasaki S

更新日期：1993-07-15 00:00:00

abstract：:The rSK3 gene encodes a small conductance Ca(2+)-activated K(+) channel that is transcriptionally regulated by estrogen. To examine determinants of rSK3 gene expression, the CAP site was defined and the promoter was identified. A 33 bp sequence adjacent to the promoter was shown to act as an enhancer in L6 cells that ...

journal_title：Biochemical and biophysical research communications

authors： Jacobson D,Pribnow D,Herson PS,Maylie J,Adelman JP

更新日期：2003-04-04 00:00:00

abstract：:GALIG, an internal gene to the human galectin-3 gene, encodes two distinct proteins, Mitogaligin and Cytogaligin through translation of a unique mRNA in two overlapping alternative reading frames. When overexpressed GALIG induces apoptosis. In cultured cells, Mitogaligin destabilizes mitochondria membranes through int...

journal_title：Biochemical and biophysical research communications

authors： El Haddad S,Serrano A,Normand T,Robin C,Dubois M,Brulé-Morabito F,Mollet L,Charpentier S,Legrand A

更新日期：2018-01-01 00:00:00

abstract：:Diverse inner arm dyneins cooperate with outer arm dyneins to produce ciliary beating. This study demonstrates an expression system for inner arm dyneins in Tetrahymena. The motor domain of inner arm dynein (Dyh8p or Dyh12p) was fused with the tail of outer arm dynein (Dyh3p) and expressed in viable DYH3-knockout (vKO...

journal_title：Biochemical and biophysical research communications

authors： Edamatsu M

更新日期：2020-02-26 00:00:00

abstract：:Fibronectin, von Willebrand factor, and fibrinogen each bind to the glycoprotein IIb-IIIa complex on activated platelets via an arg-gly-asp-ser (RGDS) sequence present within the adhesive proteins. Both the IIb and IIIa polypeptides of the IIb-IIIa complex on thrombin activated platelets are specifically and extensive...

journal_title：Biochemical and biophysical research communications

authors： Santoro SA,Lawing WJ Jr

更新日期：1989-04-14 00:00:00

abstract：:Aberrant activation of the Wnt/β-catenin signaling pathway is common in human cervical cancers and has great potential therapeutic value. We show that tigecycline, a FDA-approved antibiotic drug, targets cervical squamous cell carcinoma through inhibiting Wnt/β-catenin signaling pathway. Tigecycline is effective in in...

journal_title：Biochemical and biophysical research communications

authors： Li H,Jiao S,Li X,Banu H,Hamal S,Wang X

更新日期：2015-11-06 00:00:00

abstract：:Hepatitis C virus (HCV) affects 2-3% of the global population. Approximately one-quarter of acute infections cause chronic hepatitis that leads to liver cirrhosis or hepatocellular carcinoma. The major obstacle of current research is the extremely narrow host tropism of HCV. A single HCV strain can replicate in the Hu...

journal_title：Biochemical and biophysical research communications

authors： Lee U,Nam YR,Ye JS,Lee KJ,Kim N,Joo CH

更新日期：2014-07-25 00:00:00

abstract：:We have used site-directed mutagenesis to investigate the requirement of cysteine residues in the extracellular domains of the human VIP 1 receptor for binding VIP. Cys37, Cys50, Cys63, Cys72, Cys86, Cys105 and Cys122 (N-terminal extracellular domain), Cys208 and Cys215 (second extracellular loop) and Cys288 (third ex...

journal_title：Biochemical and biophysical research communications

authors： Gaudin P,Couvineau A,Maoret JJ,Rouyer-Fessard C,Laburthe M

更新日期：1995-06-26 00:00:00

abstract：:Intestinal epithelial cells participate in an acute phase response (APR) by responding to cytokines and by expressing acute phase protein genes. We hypothesized that butyrate, a fermentation product of the bacterial intestinal flora with deacetylase activity, affects the APR in intestinal epithelial cells. Sodium buty...

journal_title：Biochemical and biophysical research communications

authors： Désilets A,Gheorghiu I,Yu SJ,Seidman EG,Asselin C

更新日期：2000-09-24 00:00:00

abstract：:Long-term glucocorticoid (GC) usage may cause non-traumatic femoral head osteonecrosis. Dexamethasone (Dex) is shown to exert potent cytotoxic effect to osteoblasts. Here, we investigated the potential activity of α-melanocyte stimulating hormone (α-MSH) against the process. Our data revealed that pretreatment of α-MS...

journal_title：Biochemical and biophysical research communications

authors： Guo S,Xie Y,Fan JB,Ji F,Wang S,Fei H

更新日期：2016-01-08 00:00:00

abstract：:Prostaglandins are known to be involved in bone metabolism as evidenced by the ability of PGE2 to induce bone resorption. It was, therefore, of interest to determine if there was an association of specific prostaglandin metabolites with the various stages of developing bone by utilizing the matrix-induced endochondral...

journal_title：Biochemical and biophysical research communications

authors： Wientroub S,Wahl LM,Feuerstein N,Winter CC,Reddi AH

更新日期：1983-12-28 00:00:00

abstract：:Ferrous oxygenated (Fe(II)O2) hemoglobins (Hb's) and myoglobins (Mb's) have been shown to react very rapidly with NO, yielding NO3(-) and the ferric heme-protein derivative (Fe(III)), by means of the ferric heme-bound peroxynitrite intermediate (Fe(III)OONO), according to the minimum reaction scheme: Fe(II)O2 + NO (k(...

journal_title：Biochemical and biophysical research communications

authors： Ascenzi P,Bocedi A,Bolognesi M,Fabozzi G,Milani M,Visca P

更新日期：2006-01-06 00:00:00

abstract：:Human natural killer enhancing factor genes (NKEF-A and B) share extensive homology with several genes from other organisms known to be induced by oxidative stress and to protect organisms and proteins from oxidative destruction. In this study, we have identified natural killer enhancing factor as an abundant protein ...

journal_title：Biochemical and biophysical research communications

authors： Shau H,Kim A

更新日期：1994-02-28 00:00:00

abstract：:The observation that spermine inhibits the endotoxin (lipopolysaccharide; LPS) induced production of nitric oxide (NO) in macrophages has been ascribed to the conversion of SP to active metabolites by the action of enzymes, such as diamine oxidases, found, for example, in bovine sera. Inhibitory effect is also observe...

journal_title：Biochemical and biophysical research communications

authors： Southan GJ,Szabó C,Thiemermann C

更新日期：1994-09-30 00:00:00

abstract：:Ubiquitin C-terminal hydrolase-L3 (UCH-L3) is among the deubiquitinating enzymes (DUBs) that cleave ubiquitin (Ub) from Ub precursors or protein substrates. Many DUBs have been shown to participate in cancer progression in various tissues. However, the mechanism and role of UCH-L3 in carcinogenesis has largely been un...

journal_title：Biochemical and biophysical research communications

authors： Song HM,Lee JE,Kim JH

更新日期：2014-09-26 00:00:00

abstract：:Cancer cells enhance autophagic activity as a survival measure against metabolic and therapeutic stresses. The inhibition of autophagy may represent a valuable sensitizing target for cancer treatment. Recently, we examined the ability of various cytochalasins to inhibit autophagy and demonstrated the potent inhibitory...

journal_title：Biochemical and biophysical research communications

authors： Takanezawa Y,Nakamura R,Kojima Y,Sone Y,Uraguchi S,Kiyono M

更新日期：2018-04-06 00:00:00

abstract：:Engineering of secreted protease variants exhibiting altered substrate specificity is a challenging task because effective screening methods for the desired property are not available yet. In this study, we sought to obtain variants of Kex2, a yeast Golgi protease, which exhibit altered P2 specificity. We first random...

journal_title：Biochemical and biophysical research communications

authors： Han HE,Rho SH,Lee YJ,Park WJ

更新日期：2005-12-02 00:00:00