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Identification of natural killer enhancing factor as a major antioxidant in human red blood cells.

Abstract：

:Human natural killer enhancing factor genes (NKEF-A and B) share extensive homology with several genes from other organisms known to be induced by oxidative stress and to protect organisms and proteins from oxidative destruction. In this study, we have identified natural killer enhancing factor as an abundant protein in red blood cell cytosol. Highly purified natural killer enhancing factor blocks inactivation of enzymes by mixed metal-thiol oxidation. Thus, natural killer enhancing factor is a major antioxidant protecting red blood cells from oxidative injuries.

journal_name

Biochem Biophys Res Commun

journal_title

Biochemical and biophysical research communications

authors

Shau H,Kim A

doi

10.1006/bbrc.1994.1197

subject

Has Abstract

pub_date

1994-02-28 00:00:00

pages

83-8

issue

1

eissn

0006-291X

issn

1090-2104

pii

S0006291X84711971

journal_volume

199

pub_type

杂志文章

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